ZA977596B - Process for preparing paclitaxel. - Google Patents

Process for preparing paclitaxel.

Info

Publication number: ZA977596B
Authority: ZA; South Africa
Prior art keywords: preparing paclitaxel; paclitaxel; preparing
Prior art date: 1996-08-27

Application number

ZA9707596A

Other languages

English (en)

Inventor

Kyoung Soo Kim

Ki Byung Chai

Young Ho Moon

Kwang Ok Lee

Nam Du Kim

Tae Hee Ha

Jung Ae Shin

Gwan Sun Lee

Wan Joo Kim

Original Assignee

Hanmi Pharm Ind Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-27

Filing date

1997-08-25

Publication date

1998-04-06

1997-08-25 Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd

1998-04-06 Publication of ZA977596B publication Critical patent/ZA977596B/xx

Links

229930012538 Paclitaxel Natural products 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229960001592 paclitaxel Drugs 0.000 title 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ZA9707596A 1996-08-27 1997-08-25 Process for preparing paclitaxel. ZA977596B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
KR19960035754		1996-08-27

Publications (1)

Publication Number	Publication Date
ZA977596B true ZA977596B (en)	1998-04-06

Family

ID=19470938

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9707596A ZA977596B (en)	1996-08-27	1997-08-25	Process for preparing paclitaxel.

Country Status (17)

Country	Link
US (1)	US6130336A (de)
EP (1)	EP0923565B1 (de)
JP (1)	JP3294280B2 (de)
KR (1)	KR100225535B1 (de)
AR (1)	AR009349A1 (de)
AT (1)	ATE208383T1 (de)
AU (1)	AU3953297A (de)
DE (1)	DE69708126T2 (de)
DK (1)	DK0923565T3 (de)
ES (1)	ES2167777T3 (de)
ID (1)	ID19799A (de)
IL (1)	IL121599A (de)
PT (1)	PT923565E (de)
TR (1)	TR199700863A2 (de)
WO (1)	WO1998008832A1 (de)
YU (1)	YU35997A (de)
ZA (1)	ZA977596B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5917062A (en) *	1997-11-21	1999-06-29	Indena S.P.A	Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
IT1308636B1 (it)	1999-03-02	2002-01-09	Indena Spa	Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
US6900342B2 (en) *	2002-05-10	2005-05-31	Dabur India Limited	Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
DK1854799T3 (da) *	2006-05-12	2011-07-18	Indena Spa	Fremgangsmåde til fremstilling af et taxanderivat
WO2016098015A1 (en) *	2014-12-16	2016-06-23	Khashayar Karimian	New efficient methods for the synthesis of taxane derivatives such as docetaxel and their structural analogous, and a method for the preparation thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2688499B1 (fr)	1992-03-10	1994-05-06	Rhone Poulenc Rorer Sa	Procede de preparation de la beta-phenylisoserine et de ses analogues.
US5948919A (en) *	1993-02-05	1999-09-07	Napro Biotherapeutics, Inc.	Paclitaxel synthesis from precursor compounds and methods of producing the same
FR2702212B1 (fr)	1993-03-02	1995-04-07	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5475011A (en) *	1993-03-26	1995-12-12	The Research Foundation Of State University Of New York	Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
FR2706457B1 (fr) *	1993-06-16	1995-07-28	Rhone Poulenc Rorer Sa	Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
CA2170661A1 (en) *	1995-03-22	1996-09-23	John K. Thottathil	Novel methods for the preparation of taxanes using oaxzolidine intermediates
US5675025A (en) *	1995-06-07	1997-10-07	Napro Biotherapeutics, Inc.	Paclitaxel synthesis from precursor compounds and methods of producing the same
FR2740451B1 (fr) *	1995-10-27	1998-01-16	Seripharm	Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
DE69715417T2 (de) *	1996-05-08	2003-06-05	Pharmacia & Upjohn Co., Kalamazoo	Oxazolidinester
US5635531A (en) *	1996-07-08	1997-06-03	Bristol-Myers Squibb Company	3'-aminocarbonyloxy paclitaxels

1997
- 1997-08-20 KR KR1019970039557A patent/KR100225535B1/ko not_active Expired - Fee Related
- 1997-08-21 IL IL12159997A patent/IL121599A/en not_active IP Right Cessation
- 1997-08-25 ZA ZA9707596A patent/ZA977596B/xx unknown
- 1997-08-25 DK DK97936872T patent/DK0923565T3/da active
- 1997-08-25 PT PT97936872T patent/PT923565E/pt unknown
- 1997-08-25 DE DE69708126T patent/DE69708126T2/de not_active Expired - Lifetime
- 1997-08-25 WO PCT/KR1997/000157 patent/WO1998008832A1/en not_active Ceased
- 1997-08-25 AU AU39532/97A patent/AU3953297A/en not_active Abandoned
- 1997-08-25 ES ES97936872T patent/ES2167777T3/es not_active Expired - Lifetime
- 1997-08-25 AT AT97936872T patent/ATE208383T1/de active
- 1997-08-25 EP EP97936872A patent/EP0923565B1/de not_active Expired - Lifetime
- 1997-08-25 US US09/242,736 patent/US6130336A/en not_active Expired - Fee Related
- 1997-08-25 JP JP51149698A patent/JP3294280B2/ja not_active Expired - Fee Related
- 1997-08-27 TR TR97/00863A patent/TR199700863A2/xx unknown
- 1997-08-27 YU YU35997A patent/YU35997A/sh unknown
- 1997-08-27 AR ARP970103887A patent/AR009349A1/es active IP Right Grant
- 1997-08-27 ID IDP972984A patent/ID19799A/id unknown

Also Published As

Publication number	Publication date
WO1998008832A1 (en)	1998-03-05
IL121599A0 (en)	1998-02-08
ES2167777T3 (es)	2002-05-16
ATE208383T1 (de)	2001-11-15
AU3953297A (en)	1998-03-19
IL121599A (en)	2004-06-20
JP3294280B2 (ja)	2002-06-24
DE69708126D1 (de)	2001-12-13
ID19799A (id)	1998-08-06
US6130336A (en)	2000-10-10
TR199700863A3 (tr)	1999-10-21
JP2000501425A (ja)	2000-02-08
EP0923565A1 (de)	1999-06-23
PT923565E (pt)	2002-04-29
KR100225535B1 (ko)	1999-10-15
DK0923565T3 (da)	2001-12-27
AR009349A1 (es)	2000-04-12
TR199700863A2 (xx)	1999-10-21
EP0923565B1 (de)	2001-11-07
KR19980018801A (ko)	1998-06-05
DE69708126T2 (de)	2002-07-11
YU35997A (sh)	1999-09-27

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