ZA9810136B - Anti-estrogen plus progestin containing oral contraceptives. - Google Patents

Anti-estrogen plus progestin containing oral contraceptives.

Info

Publication number
ZA9810136B
ZA9810136B ZA9810136A ZA9810136A ZA9810136B ZA 9810136 B ZA9810136 B ZA 9810136B ZA 9810136 A ZA9810136 A ZA 9810136A ZA 9810136 A ZA9810136 A ZA 9810136A ZA 9810136 B ZA9810136 B ZA 9810136B
Authority
ZA
South Africa
Prior art keywords
oral contraceptives
containing oral
estrogen plus
plus progestin
progestin containing
Prior art date
Application number
ZA9810136A
Other languages
English (en)
Inventor
Michael Jay Gast
Christopher Paul Miller
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA9810136B publication Critical patent/ZA9810136B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA9810136A 1997-11-06 1998-11-05 Anti-estrogen plus progestin containing oral contraceptives. ZA9810136B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96508397A 1997-11-06 1997-11-06

Publications (1)

Publication Number Publication Date
ZA9810136B true ZA9810136B (en) 2000-05-05

Family

ID=25509417

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810136A ZA9810136B (en) 1997-11-06 1998-11-05 Anti-estrogen plus progestin containing oral contraceptives.

Country Status (28)

Country Link
EP (1) EP1051179B1 (cs)
JP (1) JP2001522798A (cs)
CN (1) CN1278732A (cs)
AR (1) AR016667A1 (cs)
AT (1) ATE304359T1 (cs)
AU (2) AU760540B2 (cs)
BG (1) BG104451A (cs)
BR (1) BR9813982A (cs)
CA (1) CA2307210A1 (cs)
CZ (1) CZ294155B6 (cs)
DE (1) DE69831605T2 (cs)
DK (1) DK1051179T3 (cs)
EA (1) EA200000492A1 (cs)
EE (1) EE04092B1 (cs)
ES (1) ES2246541T3 (cs)
GE (1) GEP20043290B (cs)
HR (1) HRP20000269A2 (cs)
HU (1) HUP0100293A3 (cs)
ID (1) ID24568A (cs)
IL (1) IL135621A0 (cs)
NO (1) NO20002167L (cs)
NZ (1) NZ503890A (cs)
PL (1) PL340623A1 (cs)
SK (1) SK6482000A3 (cs)
TR (1) TR200001268T2 (cs)
UA (1) UA68365C2 (cs)
WO (1) WO1999024027A2 (cs)
ZA (1) ZA9810136B (cs)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120263A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to prevent bone loss-progesterone and estrogen agonists
ID26890A (id) * 1998-05-15 2001-02-15 American Home Prod 2-fenil-1-(4-(2-aminoetoksi) -benzil)-indol dalam kombinasinya dengan estrogen
US6479535B1 (en) 1998-05-15 2002-11-12 Wyeth 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
HK1044777B (en) * 1999-09-13 2006-04-13 Wyeth Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1h-indol-5-ols
US6380166B1 (en) 1999-09-13 2002-04-30 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
US6376486B1 (en) * 2000-07-06 2002-04-23 American Home Products Corporation Methods of inhibiting sphincter incontinence
EP1411922A1 (en) 2001-07-31 2004-04-28 Pfizer Products Inc. Pharmaceutical compositions, kits and methods comprising combinations of estrogen agonists/antagonists, estrogens and progestins
EP1809602B1 (en) * 2004-10-27 2008-10-29 Janssen Pharmaceutica N.V. Indole derivatives useful as progesterone receptor modulators
FR2880625B1 (fr) * 2005-01-07 2007-03-09 Sanofi Aventis Sa Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
UY29527A1 (es) * 2005-05-13 2006-12-29 Schering Ag Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato.
DE102008057230A1 (de) * 2008-11-11 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Synergistische pharmazeutische Kombination mit einem Estrogenrezeptorantagonisten und einem Progestin
HUE033581T2 (hu) 2010-06-10 2017-12-28 Seragon Pharmaceuticals Inc Ösztrogén receptor modulátorok és alkalmazásaik
JP6112625B2 (ja) 2011-12-14 2017-04-12 セラゴン ファーマシューティカルズ,インク. フッ素化したエストロゲン受容体モジュレーターおよびその使用
KR102710603B1 (ko) 2015-10-01 2024-09-27 올레마 파마슈티컬스 인코포레이티드 테트라히드로-1H-피리도[3,4-b]인돌 항에스트로겐 약물
SMT202300018T1 (it) 2015-12-09 2023-03-17 Univ Illinois Downregolatori del recettore degli estrogeni a base di benzotiofene
CN109641874A (zh) 2016-05-10 2019-04-16 C4医药公司 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体
EP4491236A3 (en) 2016-05-10 2025-04-02 C4 Therapeutics, Inc. Heterocyclic degronimers for target protein degradation
EP3454862B1 (en) 2016-05-10 2024-09-11 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
CN109790143A (zh) 2016-05-10 2019-05-21 C4医药公司 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体
EP3858835A1 (en) 2016-07-01 2021-08-04 G1 Therapeutics, Inc. Pyrimidine-based antiproliferative agents
WO2018081168A2 (en) 2016-10-24 2018-05-03 The Board Of Trustees Of The University Of Illinois Benzothiophene-based selective mixed estrogen receptor downregulators
EP3565558B1 (en) 2017-01-06 2023-12-06 G1 Therapeutics, Inc. Combination therapy with a serd compound and a cdk4/6 inhibitor for the treatment of cancer
KR20190117582A (ko) 2017-02-10 2019-10-16 쥐원 쎄라퓨틱스, 인크. 벤조티오펜 에스트로겐 수용체 조정제
EP4717317A2 (en) 2017-06-20 2026-04-01 C4 Therapeutics, Inc. N/o-linked degrons and degronimers for protein degradation
FI3645001T3 (fi) 2017-06-29 2024-09-25 G1 Therapeutics Inc Git38:n morfisia muotoja ja niiden valmistusmenetelmiä
CN120698983A (zh) 2018-12-20 2025-09-26 C4医药公司 靶向蛋白降解
MX2022000279A (es) 2019-07-07 2022-02-03 Olema Pharmaceuticals Inc Regimenes de antagonistas del receptor de estrogeno.
BR112022011827A2 (pt) 2019-12-20 2022-08-30 C4 Therapeutics Inc Composto, composição farmacêutica, uso de um composto, métodos para tratamento ou profilaxia de câncer e para tratar um paciente com um distúrbio mediado por receptor do fator de crescimento epidérmico, e, invenção
AU2021231898A1 (en) 2020-03-05 2022-10-27 C4 Therapeutics, Inc. Compounds for targeted degradation of BRD9
EP4192458A4 (en) 2020-08-05 2024-09-04 C4 Therapeutics, Inc. COMPOUNDS FOR TARGETED DEGRADATION OF RET
WO2022261250A1 (en) 2021-06-08 2022-12-15 C4 Therapeutics, Inc. Therapeutics for the degradation of mutant braf
JP2025525917A (ja) 2022-08-03 2025-08-07 ブリストル-マイヤーズ スクイブ カンパニー Retタンパク質を調節するための化合物
CN120530116A (zh) 2022-11-04 2025-08-22 百时美施贵宝公司 Ret-ldd蛋白抑制剂
CN120569388A (zh) 2022-11-04 2025-08-29 百时美施贵宝公司 Ret-ldd蛋白降解剂
WO2025006753A2 (en) 2023-06-30 2025-01-02 Merck Patent Gmbh Heterobifunctional compounds for the degradation of kras protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA716118B (en) * 1970-10-05 1972-05-31 Richardson Merrell Inc Contraception
ZA9510926B (en) * 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
IL120263A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to prevent bone loss-progesterone and estrogen agonists
IL120266A (en) * 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
DE69707189T2 (de) * 1996-04-19 2002-06-20 American Home Products Corp., Madison Östrogene Verbindungen
US5747480A (en) * 1996-05-08 1998-05-05 American Home Products Corporation Oral contraceptive

Also Published As

Publication number Publication date
EE200000211A (et) 2001-04-16
CA2307210A1 (en) 1999-05-20
AU760540B2 (en) 2003-05-15
ID24568A (id) 2000-07-27
EP1051179A2 (en) 2000-11-15
EA200000492A1 (ru) 2000-10-30
NO20002167L (no) 2000-06-28
PL340623A1 (en) 2001-02-12
DK1051179T3 (da) 2005-10-31
WO1999024027A3 (en) 1999-07-15
ES2246541T3 (es) 2006-02-16
NO20002167D0 (no) 2000-04-27
ATE304359T1 (de) 2005-09-15
WO1999024027A2 (en) 1999-05-20
CZ20001661A3 (cs) 2000-12-13
HUP0100293A3 (en) 2002-12-28
AU2003204896B2 (en) 2006-06-15
NZ503890A (en) 2002-08-28
EP1051179B1 (en) 2005-09-14
BG104451A (en) 2000-12-29
JP2001522798A (ja) 2001-11-20
CZ294155B6 (cs) 2004-10-13
AR016667A1 (es) 2001-07-25
DE69831605T2 (de) 2006-06-14
HRP20000269A2 (en) 2000-12-31
HUP0100293A2 (hu) 2001-10-28
SK6482000A3 (en) 2000-11-07
AU1303199A (en) 1999-05-31
DE69831605D1 (de) 2005-10-20
CN1278732A (zh) 2001-01-03
GEP20043290B (en) 2004-07-26
EE04092B1 (et) 2003-08-15
TR200001268T2 (tr) 2001-01-22
BR9813982A (pt) 2000-09-26
UA68365C2 (en) 2004-08-16
IL135621A0 (en) 2001-05-20

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