ZA981352B - Pharmaceutical preparation comprising lyophilized liposomes encapsulating an active principle which is highly insoluble in water and the process for preparing the said preparation - Google Patents

Pharmaceutical preparation comprising lyophilized liposomes encapsulating an active principle which is highly insoluble in water and the process for preparing the said preparation

Info

Publication number
ZA981352B
ZA981352B ZA981352A ZA981352A ZA981352B ZA 981352 B ZA981352 B ZA 981352B ZA 981352 A ZA981352 A ZA 981352A ZA 981352 A ZA981352 A ZA 981352A ZA 981352 B ZA981352 B ZA 981352B
Authority
ZA
South Africa
Prior art keywords
preparation
preparing
water
active principle
highly insoluble
Prior art date
Application number
ZA981352A
Other languages
English (en)
Inventor
Giovanni Cavallo
Leonardo Marchitto
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Publication of ZA981352B publication Critical patent/ZA981352B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA981352A 1997-02-20 1998-02-18 Pharmaceutical preparation comprising lyophilized liposomes encapsulating an active principle which is highly insoluble in water and the process for preparing the said preparation ZA981352B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000362A IT1289938B1 (it) 1997-02-20 1997-02-20 Preparazione farmaceutica comprendente liposomi liofilizzati in cui e' incapsulato un principio attivo altamente insolubile in acqua e

Publications (1)

Publication Number Publication Date
ZA981352B true ZA981352B (en) 1998-08-19

Family

ID=11376097

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981352A ZA981352B (en) 1997-02-20 1998-02-18 Pharmaceutical preparation comprising lyophilized liposomes encapsulating an active principle which is highly insoluble in water and the process for preparing the said preparation

Country Status (25)

Country Link
US (1) US6319517B1 (de)
EP (1) EP0981332B1 (de)
JP (1) JP4290767B2 (de)
KR (1) KR100496802B1 (de)
CN (1) CN1089581C (de)
AR (1) AR011681A1 (de)
AT (1) ATE285754T1 (de)
AU (1) AU744115B2 (de)
BG (1) BG64580B1 (de)
CA (1) CA2288958C (de)
CZ (1) CZ295998B6 (de)
DE (1) DE69828394T2 (de)
EA (1) EA001637B1 (de)
ES (1) ES2235320T3 (de)
GE (1) GEP20022734B (de)
HU (1) HU225593B1 (de)
IL (1) IL131327A (de)
IT (1) IT1289938B1 (de)
PL (1) PL190628B1 (de)
PT (1) PT981332E (de)
SK (1) SK282931B6 (de)
TR (1) TR199902025T2 (de)
UA (1) UA70296C2 (de)
WO (1) WO1998036736A1 (de)
ZA (1) ZA981352B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000079283A1 (en) * 1999-06-23 2000-12-28 Cornell Research Foundation, Inc. Dehydration/rehydration of marked liposomes on a test device
US6576460B1 (en) 1999-10-28 2003-06-10 Cornell Research Foundation, Inc. Filtration-detection device and method of use
KR20050098249A (ko) * 2003-01-17 2005-10-11 쓰레솔드 파마슈티컬스, 인코포레이티드 양성 전립선 비대증의 치료방법
BRPI0609071A2 (pt) 2005-04-12 2010-11-16 Elan Pharma Int Ltd composicão estável de ciclosporina nanoparticulada, método para preparar uma ciclosporina nanoparticulada, uso da composição de ciclosporina nanoparticulada estável, e, composição de liberação controlada
WO2008036979A2 (en) * 2006-09-22 2008-03-27 Guilford F Timothy Topical application of melatonin directly or in liposomes for the amelioration of itching and histamine and non-histamine related inflammatory skin changes
CN101049504B (zh) * 2007-04-05 2010-05-19 广州立恩生物科技有限公司 一种脂质体药物载体及其制备方法
US9446147B2 (en) 2011-02-24 2016-09-20 The Ohio State University Membrane stabilizing compositions and methods
KR102284689B1 (ko) 2011-10-21 2021-08-02 셀라토 파마슈티칼즈, 인코포레이티드 동결건조된 리포좀
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
JP5957610B2 (ja) * 2012-08-31 2016-07-27 チュンアン ユニバーシティー インダストリー アカデミック コアポレイション ファウンデイション 塞栓用のミクロスフェアの製造方法及び薬物含有ナノ輸送体が結合されたミクロスフェアの製造方法
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
KR102649069B1 (ko) 2018-05-31 2024-03-19 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물
EP3813788A1 (de) * 2018-06-27 2021-05-05 Breath Therapeutics GmbH Pharmazeutische zusammensetzungen in lyophilisierter form
BR112020026635A2 (pt) 2018-06-27 2021-04-20 Breath Therapeutics Gmbh composições inaláveis compreendendo imunosupressores macrocíclicos
WO2020027466A1 (ko) * 2018-07-28 2020-02-06 주식회사 엑소코바이오 엑소좀의 동결건조 방법
KR102163806B1 (ko) 2018-07-30 2020-10-07 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물
EA202092892A1 (ru) 2018-12-04 2021-05-27 Брес Терапьютикс Гмбх Ингаляционные композиции, содержащие макроциклические иммуносупрессанты
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method
EP3990433B1 (de) 2019-06-25 2026-05-20 Translatum Medicus Inc Verfahren zur herstellung von 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropansäure und ihren derivaten
CN111358955B (zh) * 2020-04-01 2023-05-02 重庆理工大学 一种用于治疗脂质代谢疾病的炎症靶向的宾达利纳米粒、制备方法及其应用
JP7508359B2 (ja) * 2020-12-11 2024-07-01 株式会社東芝 脂質粒子の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
FR2542749B1 (fr) * 1983-03-18 1985-07-12 Beghin Say Sa Copolymere allyloligosaccharide-acrylique salifie, procede de preparation du copolymere et application comme super-absorbant
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
US5683714A (en) * 1991-04-19 1997-11-04 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin pharmaceutical formulation
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
GB9320668D0 (en) * 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
EP0678017B1 (de) * 1993-11-05 1998-04-01 Amgen Inc. Herstellung von liposomen und verfahren zur substanzverkapselung

Also Published As

Publication number Publication date
EP0981332A1 (de) 2000-03-01
PT981332E (pt) 2005-05-31
IT1289938B1 (it) 1998-10-19
CZ292599A3 (cs) 2000-01-12
EA001637B1 (ru) 2001-06-25
DE69828394T2 (de) 2005-12-08
BG103738A (en) 2000-05-31
KR20000075479A (ko) 2000-12-15
PL335207A1 (en) 2000-04-10
CN1089581C (zh) 2002-08-28
JP2001519776A (ja) 2001-10-23
EA199900751A1 (ru) 2000-10-30
HK1026148A1 (en) 2000-12-08
JP4290767B2 (ja) 2009-07-08
IL131327A (en) 2004-07-25
ATE285754T1 (de) 2005-01-15
HU225593B1 (en) 2007-05-02
AR011681A1 (es) 2000-08-30
SK111099A3 (en) 2000-05-16
TR199902025T2 (xx) 1999-11-22
PL190628B1 (pl) 2005-12-30
ES2235320T3 (es) 2005-07-01
HUP0001464A2 (hu) 2000-10-28
UA70296A (uk) 2004-10-15
IL131327A0 (en) 2001-01-28
AU6496998A (en) 1998-09-09
CA2288958A1 (en) 1998-08-27
US6319517B1 (en) 2001-11-20
AU744115B2 (en) 2002-02-14
EP0981332B1 (de) 2004-12-29
ITMI970362A1 (it) 1998-08-20
UA70296C2 (uk) 2004-10-15
CN1248163A (zh) 2000-03-22
HUP0001464A3 (en) 2001-12-28
CA2288958C (en) 2007-08-21
GEP20022734B (en) 2002-07-25
KR100496802B1 (ko) 2005-06-22
DE69828394D1 (de) 2005-02-03
SK282931B6 (sk) 2003-01-09
WO1998036736A1 (en) 1998-08-27
CZ295998B6 (cs) 2005-12-14
BG64580B1 (bg) 2005-08-31

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