ZA983602B - Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination - Google Patents

Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination

Info

Publication number
ZA983602B
ZA983602B ZA983602A ZA983602A ZA983602B ZA 983602 B ZA983602 B ZA 983602B ZA 983602 A ZA983602 A ZA 983602A ZA 983602 A ZA983602 A ZA 983602A ZA 983602 B ZA983602 B ZA 983602B
Authority
ZA
South Africa
Prior art keywords
drugs
diseases
preparation
treatment
tetrahydropyridine derivatives
Prior art date
Application number
ZA983602A
Other languages
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Jean-Pierre Maffrand
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA983602B publication Critical patent/ZA983602B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA983602A 1997-04-29 1998-04-29 Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination ZA983602B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9705275A FR2762514B1 (fr) 1997-04-29 1997-04-29 Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation

Publications (1)

Publication Number Publication Date
ZA983602B true ZA983602B (en) 1998-11-02

Family

ID=9506415

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA983602A ZA983602B (en) 1997-04-29 1998-04-29 Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination

Country Status (18)

Country Link
US (1) US6344464B1 (da)
EP (1) EP0979079B1 (da)
JP (1) JP3956059B2 (da)
AR (1) AR012504A1 (da)
AT (1) ATE269077T1 (da)
AU (1) AU7436498A (da)
BR (1) BR9810234A (da)
CA (1) CA2288241C (da)
DE (1) DE69824576T2 (da)
DK (1) DK0979079T3 (da)
ES (1) ES2222593T3 (da)
FR (1) FR2762514B1 (da)
NO (1) NO325163B1 (da)
PT (1) PT979079E (da)
SI (1) SI0979079T1 (da)
UY (1) UY24973A1 (da)
WO (1) WO1998048802A1 (da)
ZA (1) ZA983602B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
US7186720B2 (en) 2001-04-20 2007-03-06 Sanofi-Aventis Tetrahydropyridyl-alkyl-heterocycles, method for preparing the same and pharmaceutical compositions containing the same
FR2823748B1 (fr) * 2001-04-20 2004-02-20 Sanofi Synthelabo Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant
WO2003002187A2 (en) * 2001-06-26 2003-01-09 Photomed Technologies, Inc. Multiple wavelength illuminator
EP2295081B1 (en) 2001-06-26 2018-10-31 Amgen Inc. Antibodies to OPGL
FR2831166B1 (fr) * 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
KR101317045B1 (ko) 2002-09-06 2013-10-16 암젠 인코포레이티드 치료학적 인체 항-ｉｌ-1ｒ1 모노클로날 항체
WO2004060911A2 (en) * 2002-12-30 2004-07-22 Amgen Inc. Combination therapy with co-stimulatory factors
US7838522B2 (en) 2004-11-17 2010-11-23 Ares Trading S.A. Benzothiazole formulations and use thereof
PT1828160E (pt) 2004-12-21 2012-01-05 Merck Serono Sa Derivados cíclicos de sulfonilamino e sua utilização
RS51957B (sr) 2005-01-31 2012-02-29 Merck Serono Sa. Derivati n-hidroksiamida i njihova upotreba
BRPI0613042A2 (pt) 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
RS52116B (sr) * 2005-07-15 2012-08-31 Merck Serono Sa Glepp-1 inhibitori u lečenju autoimunih i/ili inflamatornih poremećaja
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 ｊｎｋ 억제제
EA013816B1 (ru) 2005-09-01 2010-08-30 Арес Трейдинг С.А. Лечение неврита зрительного нерва
JP2011504505A (ja) * 2007-11-21 2011-02-10 デコード ジェネティクス イーエイチエフ 肺および心血管障害を治療するためのビアリールｐｄｅ４抑制剤
KR101707597B1 (ko) * 2010-12-07 2017-02-17 한국전자통신연구원 홀 센서리스 ｂｌｄｃ 모터용 전원 공급 모듈
US12403181B2 (en) 2018-08-13 2025-09-02 Iltoo Pharma Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
EP4452267B1 (en) 2021-12-23 2025-04-23 Cilcare Dev 4-phenyl-tetrahydropyridine derivatives for treating hearing diseases
WO2023222565A1 (en) 2022-05-16 2023-11-23 Institut National de la Santé et de la Recherche Médicale Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
FR2662355B1 (fr) 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2740343B1 (fr) * 1995-10-26 1999-01-22 Sanofi Sa Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique

Also Published As

Publication number Publication date
US6344464B1 (en) 2002-02-05
JP3956059B2 (ja) 2007-08-08
AR012504A1 (es) 2000-10-18
ES2222593T3 (es) 2005-02-01
WO1998048802A1 (fr) 1998-11-05
FR2762514A1 (fr) 1998-10-30
SI0979079T1 (en) 2004-10-31
AU7436498A (en) 1998-11-24
FR2762514B1 (fr) 1999-10-22
EP0979079B1 (fr) 2004-06-16
BR9810234A (pt) 2000-09-19
UY24973A1 (es) 1998-07-16
EP0979079A1 (fr) 2000-02-16
NO995245L (no) 1999-12-27
PT979079E (pt) 2004-10-29
DE69824576T2 (de) 2005-06-30
NO995245D0 (no) 1999-10-27
JP2002501498A (ja) 2002-01-15
DK0979079T3 (da) 2004-10-25
CA2288241C (en) 2006-10-03
ATE269077T1 (de) 2004-07-15
DE69824576D1 (de) 2004-07-22
NO325163B1 (no) 2008-02-11
CA2288241A1 (en) 1998-11-05

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