ZA984798B - Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus - Google Patents

Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus

Info

Publication number
ZA984798B
ZA984798B ZA984798A ZA984798A ZA984798B ZA 984798 B ZA984798 B ZA 984798B ZA 984798 A ZA984798 A ZA 984798A ZA 984798 A ZA984798 A ZA 984798A ZA 984798 B ZA984798 B ZA 984798B
Authority
ZA
South Africa
Prior art keywords
progressing
risk
treatment
disease states
polycystic ovary
Prior art date
Application number
ZA984798A
Other languages
English (en)
Inventor
Tammy Antonucci
Dean Lockwood
Rebecca Norris
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA984798B publication Critical patent/ZA984798B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA984798A 1997-06-04 1998-06-03 Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus ZA984798B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/868,608 US6046222A (en) 1993-09-15 1997-06-04 Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus

Publications (1)

Publication Number Publication Date
ZA984798B true ZA984798B (en) 1998-12-29

Family

ID=25352002

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA984798A ZA984798B (en) 1997-06-04 1998-06-03 Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus

Country Status (15)

Country Link
US (3) US6046222A (is)
EP (1) EP0984780B1 (is)
JP (1) JP2002511859A (is)
KR (1) KR20010013337A (is)
AT (1) ATE303147T1 (is)
BR (1) BR9809968A (is)
CA (1) CA2283319A1 (is)
DE (1) DE69831406D1 (is)
HU (1) HUP0003876A3 (is)
IL (1) IL131801A0 (is)
IS (1) IS5194A (is)
NO (1) NO995932L (is)
PL (1) PL348773A1 (is)
WO (1) WO1998055121A1 (is)
ZA (1) ZA984798B (is)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046222A (en) * 1993-09-15 2000-04-04 Warner-Lambert Company Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
US20020177612A1 (en) * 1997-06-05 2002-11-28 Smithkline Beecham P.I.C. Composition comprising 5-[4-[2-(N-methyl-N-2-pyridy)amino)ethoxy]benzyl]thiazolidine-2,4-dione
US20010031776A1 (en) * 1997-10-13 2001-10-18 Smithkline Beecham P.L.C. Use of thiazolidinediones for the treatment of hyperglycaemia
US20020006939A1 (en) * 1997-10-13 2002-01-17 Smithkline Beecham P.L.C. Use of thiazolidinediones for the treatment of hyperglycaemia
US7105552B2 (en) 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6605642B2 (en) 1999-04-05 2003-08-12 City Of Hope Inhibitors of formation of advanced glycation endproducts (AGES)
US7030133B2 (en) 1999-04-05 2006-04-18 City Of Hope Inhibitors of formation of advanced glycation endproducts (AGEs)
US7407978B2 (en) * 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
EP1210087A2 (en) * 1999-04-29 2002-06-05 City of Hope Pentoxifylline, pioglitazone and metformin are inhibitors of formation of advanced glycation endproducts (age's)
US6468507B1 (en) * 2000-05-01 2002-10-22 Aeropharm Technology, Inc. Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer
PT1333887E (pt) * 2000-10-30 2006-10-31 Ortho Mcneil Pharm Inc Metodo de tratamento de desordens musculares
CN100577175C (zh) * 2001-04-04 2010-01-06 奥索-麦克尼尔药品公司 包括葡萄糖重吸收抑制剂和ppar调节剂的联合疗法
WO2002080935A1 (en) * 2001-04-04 2002-10-17 Ortho Mcneil Pharmaceutical, Inc. Combination therapy comprising glucose reabsorption inhibitors and retinoid-x receptor modulators
GB0108863D0 (en) * 2001-04-10 2001-05-30 Leuven K U Res & Dev Combinational therapy
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
KR100450700B1 (ko) 2002-03-22 2004-10-01 주식회사종근당 티아졸리딘디온 유도체 화합물 및 이를 함유하는 약제학적조성물
US20030220300A1 (en) * 2002-05-14 2003-11-27 Hwang Cheng Shine Reduction of hair growth
US8911781B2 (en) 2002-06-17 2014-12-16 Inventia Healthcare Private Limited Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides
US20050107387A1 (en) * 2003-05-13 2005-05-19 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
EP1682114A2 (en) 2003-10-27 2006-07-26 City of Hope Methods of lowering lipid levels in a mammal
US20050112075A1 (en) * 2003-11-25 2005-05-26 Hwang Cheng S. Reduction of hair growth
US20050249685A1 (en) * 2004-04-27 2005-11-10 Natalia Botchkareva Reduction of hair growth
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
CA2589875A1 (en) * 2004-12-22 2006-06-29 The Gillette Company Reduction of hair growth
MX2007007624A (es) * 2004-12-22 2007-08-03 Gillette Co Reduccion del crecimiento del pelo con inhibidores de survivina.
US7618956B2 (en) * 2005-05-31 2009-11-17 The Gillette Company Reduction of hair growth
US20070249561A1 (en) * 2006-04-25 2007-10-25 Taylor Bradley K Pharmacological method for treatment of neuropathic pain
EP2254576B1 (en) * 2008-02-22 2013-08-28 The Ohio State University Research Foundation Androgen receptor-ablative agents
WO2011014649A1 (en) 2009-07-29 2011-02-03 Duke University Compositions and methods for inhibiting hair growth
CN102638980A (zh) 2009-10-09 2012-08-15 俄亥俄州州立大学研究基金会 噻唑烷二酮能量限制拟似剂
GB201518979D0 (en) * 2015-10-27 2015-12-09 Univ Leuven Kath Treatment of hepatic steatosis related oligo-ovulation

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3174901A (en) * 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
FR2449446A1 (fr) * 1979-02-22 1980-09-19 Somachim Medicament a base d'acide iodothyroacetiques et de sel de metformine
JPS58118577A (ja) * 1982-01-07 1983-07-14 Takeda Chem Ind Ltd チアゾリジン誘導体
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
HU210339B (en) * 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
US4873255A (en) * 1987-02-04 1989-10-10 Sankyo Company Limited Thiazolidinone derivatives, their preparation and their use
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
EP0295828A1 (en) * 1987-06-13 1988-12-21 Beecham Group Plc Novel compounds
US5194443A (en) * 1987-09-04 1993-03-16 Beecham Group P.L.C. Compounds
US5260445A (en) * 1987-09-04 1993-11-09 Beecham Group P.L.C. 2,4-thiazolidinediones
US5232925A (en) * 1987-09-04 1993-08-03 Beecham Group P.L.C. Compounds
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
US5223522A (en) * 1988-03-08 1993-06-29 Pfizer Inc. Thiazolidinedione hypoglycemic agents
WO1989008650A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione hypoglycemic agents
MX15171A (es) * 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
US5120754A (en) * 1988-03-08 1992-06-09 Pfizer Inc. Thiazolidinedione hypoglycemic agents
US4897405A (en) * 1989-04-21 1990-01-30 American Home Products Corporation Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
GB8919434D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
WO1991003474A1 (en) * 1989-08-29 1991-03-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
DE3942236A1 (de) * 1989-12-21 1991-06-27 Bosch Siemens Hausgeraete Katalytisches ueberzugsmittel, verfahren zu seiner herstellung und mit dem ueberzugsmittel erhaeltliche koch-, back-, brat- oder grillgeraete oder teile
WO1991012003A1 (en) * 1990-02-09 1991-08-22 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
GB9023583D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
GB9023585D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
US5221685A (en) * 1991-02-01 1993-06-22 Ube Industries, Ltd. Thiazoline derivative, process for preparing the same and chemical for controlling noxious organisms containing the same
ATE142631T1 (de) * 1991-06-25 1996-09-15 Pfizer Thiazolidindione als hypoglykämische wirkstoffe
WO1994001433A1 (fr) * 1992-07-13 1994-01-20 Japan Tobacco Inc. Nouveau compose de thiazolidinedione et son utilisation
US5221686A (en) * 1992-08-04 1993-06-22 American Home Products Corporation Spiro[1,2-benzisothiazole-3(2H),5'-oxazolidine]-2',4'-dione 1,1-dioxides as antihyperglycemic agents
TJ286B (en) * 1992-10-29 2000-12-13 Genentech Inc A method for treatment or prevention of obesity
US5478852C1 (en) * 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
US5874454A (en) * 1993-09-15 1999-02-23 Warner-Lambert Company Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
US6046222A (en) * 1993-09-15 2000-04-04 Warner-Lambert Company Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
NZ274346A (en) * 1993-09-15 1997-06-24 Sankyo Co Use of various thiazolidine-2,4-dione and oxazolidine-2,4-dione derivatives to prevent or delay onset of non-insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
IL131801A0 (en) 2001-03-19
HUP0003876A2 (hu) 2002-01-28
BR9809968A (pt) 2000-08-01
ATE303147T1 (de) 2005-09-15
US6046222A (en) 2000-04-04
KR20010013337A (ko) 2001-02-26
IS5194A (is) 1999-09-24
EP0984780A1 (en) 2000-03-15
DE69831406D1 (de) 2005-10-06
PL348773A1 (en) 2002-06-17
HUP0003876A3 (en) 2002-04-29
WO1998055121A1 (en) 1998-12-10
JP2002511859A (ja) 2002-04-16
CA2283319A1 (en) 1998-12-10
US5972944A (en) 1999-10-26
EP0984780B1 (en) 2005-08-31
US6130216A (en) 2000-10-10
NO995932D0 (no) 1999-12-03
NO995932L (no) 1999-12-03

Similar Documents

Publication Publication Date Title
ZA984798B (en) Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus
WO1995007697A3 (en) Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
IL213041A0 (en) Use of hypoglycemic agent for treating impaired glucose metabolism
NZ504258A (en) Exendin 3 and 4 agonist compounds for the treatment of diabetes
WO2002064210A3 (en) Combination therapy comprising anti-diabetic and anticonvulsant agents
IL188471A0 (en) Combinations of dipeptidyl peptidase iv inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
CA2294582A1 (en) Treatment of diabetes with thiazolidinedione and metformin
NO20014792D0 (no) Med sukkerrester substituerte 1,4-benzotiazepin-1,1-dioksid- derivater, fremgangsmåte for deres fremstilling, legemidler sominneholder disse og forbindelser og deres anvendelse
MY143051A (en) Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
NO20083276L (no) Behandling av diabetes med tiazolidindion og sulfonylurea
MY155219A (en) Treatment of diabetes with thiazolidinedione, insulin secretagogue and biguanide
ZA984084B (en) Use of thiazolidinedione derivatives in the treatment of polycistic ovary syndrome gestational diabetes and disease states at risk for progressing to noninsulindependent diabetes mellitus
NO984572L (no) Anvendelse av 2,5-dihydroksybenzensulfonderivater for fremstilling av legemidler ment for normalisering av den endoteliale funksjon, for behandling av seksuell dysfunksjon og vaskulµre komplikasjoner i diabetes, sÕvel som vaskulµre lidelser av e
AP9901720A0 (en) Treatment of diabetes with thiazolidinedione and alpha-glucosidase inhibitors.
EP0908180A3 (en) Use of phenyl oxazole or phenyl thiazole derivatives for treating pain
SI0998291T2 (sl) Zdravljenje diabetesa s tiazolidindionom in sulfonilseäśnino
AU6478800A (en) Novel use of polysaccharide from phellinus linteus for treating diabetes mellitus
AU2002215059A1 (en) Combination of amines and vanadium (IV)/(V) compounds for the treatment and/or prevention of diabetes mellitus
AU6648200A (en) Method and composition for preventing or treating adverse physiological effects associated with cardiac disease
HUP0301137A3 (en) Thiazolidinedione salt for treatment of diabetes mellitus, process for its preparation and pharmaceutical composition containing the same
AU2382701A (en) Thiazolidinedione derivatives in treatment of diabetes mellitus of type
WO2004082582A3 (fr) Utilisation du diazoxide dans le traitement de l'ischemie retinienne
HUP0003673A2 (hu) Dioxo-tiazolidinek alkalmazása a hyperglykaemia kezelésére
AU2003226768A1 (en) Combination of insulin and a thiazolidinedione derivative, and use thereof for treating diabetes
GB9705041D0 (en) Thiazole benzenesulfonamides as selective B3 agonists for the treatment of diabetes and obesity