ZA9894B - Specific inhibitors of pancreatic lipase and their applications - Google Patents

Specific inhibitors of pancreatic lipase and their applications

Info

Publication number
ZA9894B
ZA9894B ZA9894A ZA9894A ZA9894B ZA 9894 B ZA9894 B ZA 9894B ZA 9894 A ZA9894 A ZA 9894A ZA 9894 A ZA9894 A ZA 9894A ZA 9894 B ZA9894 B ZA 9894B
Authority
ZA
South Africa
Prior art keywords
pancreatic lipase
applications
specific inhibitors
inhibitors
lyperlipemia
Prior art date
Application number
ZA9894A
Other languages
English (en)
Inventor
Catherine Chapus
Original Assignee
Laphal Laboratoire De Pharmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laphal Laboratoire De Pharmaco filed Critical Laphal Laboratoire De Pharmaco
Publication of ZA9894B publication Critical patent/ZA9894B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA9894A 1997-01-07 1998-01-07 Specific inhibitors of pancreatic lipase and their applications ZA9894B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9700071A FR2758143B1 (fr) 1997-01-07 1997-01-07 Inhibiteurs specifiques de la lipase pancreatique et leurs applications

Publications (1)

Publication Number Publication Date
ZA9894B true ZA9894B (en) 1998-07-08

Family

ID=9502405

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9894A ZA9894B (en) 1997-01-07 1998-01-07 Specific inhibitors of pancreatic lipase and their applications

Country Status (14)

Country Link
US (1) US6432400B1 (de)
EP (1) EP0970118B1 (de)
CN (1) CN1248264A (de)
AT (1) ATE273995T1 (de)
AU (1) AU727469B2 (de)
BR (1) BR9806857A (de)
CA (1) CA2277778C (de)
CZ (1) CZ294206B6 (de)
DE (1) DE69825733T2 (de)
FR (1) FR2758143B1 (de)
HU (1) HUP0001458A3 (de)
NZ (1) NZ337087A (de)
WO (1) WO1998030588A1 (de)
ZA (1) ZA9894B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000226335A (ja) * 1998-12-04 2000-08-15 Amano Pharmaceut Co Ltd 経口用酵素製剤、酵素含有食材及び酵素製剤の服用方法
US6697668B2 (en) 2001-01-25 2004-02-24 Iomed, Inc. Ocular iontophoretic device and method for using the same
FR2824334B1 (fr) * 2001-05-03 2003-10-10 Coletica Procede pour tester une substance eventuellement active dans le domaine de la lipolyse et son utilisation principalement cosmetique
US20040018197A1 (en) * 2002-04-26 2004-01-29 Promega Corporation Treatment for weight loss
US20040077530A1 (en) * 2002-10-18 2004-04-22 Robert Portman Composition for reducing caloric intake
WO2004090551A2 (en) * 2003-04-08 2004-10-21 Genova, Ltd. Secreted polypeptide species associated with cardiovascular disorders
SE0302253D0 (sv) * 2003-08-21 2003-08-21 Forskarpatent I Syd Ab Lipase-colipase inhibitor
GB0920633D0 (en) 2009-11-25 2010-01-13 Rdbiomed Ltd Inhibition of pancreatic lipase
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
US20130144540A1 (en) * 2011-12-06 2013-06-06 Palo Alto Research Center Incorporated Constrained de novo sequencing of peptides
WO2017079299A1 (en) * 2015-11-03 2017-05-11 Mayo Foundation For Medical Education And Research Using colipase inhibitors to treat pancreatitis
EP3651784B1 (de) 2017-07-12 2022-09-28 Mayo Foundation for Medical Education and Research Verbindungen zur verringerung der lipotoxischen beschädigung
CN114621336B (zh) * 2020-12-14 2024-08-16 西北农林科技大学 一种酪蛋白源胰脂肪酶抑制肽及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248598A (en) * 1989-05-25 1993-09-28 Ivan E. Modrovich Lipase single reagent system

Also Published As

Publication number Publication date
CA2277778C (fr) 2013-07-02
FR2758143B1 (fr) 1999-02-19
US6432400B1 (en) 2002-08-13
AU727469B2 (en) 2000-12-14
NZ337087A (en) 2001-01-26
CZ294206B6 (cs) 2004-10-13
CN1248264A (zh) 2000-03-22
CZ241499A3 (cs) 2000-01-12
DE69825733T2 (de) 2005-09-01
HUP0001458A2 (hu) 2000-10-28
AU5868698A (en) 1998-08-03
WO1998030588A1 (fr) 1998-07-16
EP0970118A1 (de) 2000-01-12
CA2277778A1 (fr) 1998-07-16
ATE273995T1 (de) 2004-09-15
EP0970118B1 (de) 2004-08-18
HUP0001458A3 (en) 2001-04-28
FR2758143A1 (fr) 1998-07-10
DE69825733D1 (de) 2004-09-23
BR9806857A (pt) 2000-03-14

Similar Documents

Publication Publication Date Title
AU5868698A (en) Specific pancreatic lipase inhibitors and their applications
ZA99133B (en) Transgenic rabbit that expresses a functional human lipoprotein (A).
PT1019040E (pt) Inibicao da actividade de p38-quinase por meio de arilureias
MXPA05003493A (es) Metodos para generar y seleccionar proteasas con especificidad alterada.
PL344022A1 (en) Lipase inhibiting polymers
AU7321598A (en) Use of cholinesterase inhibitors to treat disorders of attention
MX9702204A (es) Tratamiento con ribozimas de enfermedades o condiciones relacionadas con niveles de lipoproteina (a) [lp(a)] en plasma, inhibiendo apolipoproteina (a) [apo(a)].
FR2846667B1 (fr) Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
PL336788A1 (en) Probucol monoesters in treating circulatory system and inflammatory diseases
WO2004047760A3 (en) Novel chemical compounds
DE69631471D1 (de) Verfahren zur verflüssigung von stärke
GB9924957D0 (en) Novel treatment
EP1023005A4 (de) Verfahren zum beschichten von stents mit dna sowie zur in vivo expression von rekombinanten genen von mit dna beschichteten
ATE429927T1 (de) Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
EA199700241A1 (ru) Новые, определенные по составу смеси ферментов для выделения клеток и лечения ран
PT996709E (pt) Inibidores de enzimas celuloliticas, xilanoliticas e betaglucanoliticas
DE58909121D1 (de) Katabolische Enzyme zur Induktion des Tumornekrose-Faktors (TNF).
AU1278600A (en) Novel therapeutic application of nicergoline
ID23184A (id) Garam-garam peptida bpc dengan aktivitas organoprotektif proses pembuatan dan penggunaannya dalam terapi
ATE278014T1 (de) Target zur behandlung von atherosklerose, fettleibigkeit und diabetis typ ii
AU4390597A (en) Combination therapy for treatment of arthritic diseases
WO2000037022A3 (en) Combination therapy for the treatment of sepsis
WO2004094608A3 (en) Human procolipase like nucleic acids and polypeptides and their methods of use threof
DE59902857D1 (de) Mittel zur spezifischen hemmung osteoklastärer knochenresorption
DE59813159D1 (de) Kombination der proteolytischen enzyme trypsin, bromelain und papain zur behandlung von glomerulonephritis