ZW14480A1 - Pharmaceutical ethers preparation use and intermediates therefore and their preparation - Google Patents

Pharmaceutical ethers preparation use and intermediates therefore and their preparation

Info

Publication number
ZW14480A1
ZW14480A1 ZW144/80A ZW14480A ZW14480A1 ZW 14480 A1 ZW14480 A1 ZW 14480A1 ZW 144/80 A ZW144/80 A ZW 144/80A ZW 14480 A ZW14480 A ZW 14480A ZW 14480 A1 ZW14480 A1 ZW 14480A1
Authority
ZW
Zimbabwe
Prior art keywords
preparation
intermediates
pharmaceutical
ethers
preparation use
Prior art date
Application number
ZW144/80A
Other languages
English (en)
Inventor
Geoffrey Kneen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZW14480A1 publication Critical patent/ZW14480A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZW144/80A 1979-06-29 1980-06-27 Pharmaceutical ethers preparation use and intermediates therefore and their preparation ZW14480A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7922781 1979-06-29

Publications (1)

Publication Number Publication Date
ZW14480A1 true ZW14480A1 (en) 1982-03-17

Family

ID=10506199

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW144/80A ZW14480A1 (en) 1979-06-29 1980-06-27 Pharmaceutical ethers preparation use and intermediates therefore and their preparation

Country Status (18)

Country Link
US (1) US4410537A (2)
EP (1) EP0022229B1 (2)
JP (1) JPS5649335A (2)
KR (2) KR850000073B1 (2)
AU (1) AU545274B2 (2)
DE (1) DE3061269D1 (2)
DK (1) DK159770C (2)
FI (1) FI71929C (2)
GB (1) GB2053218B (2)
GR (1) GR68748B (2)
HU (1) HU190774B (2)
IL (1) IL60422A (2)
IT (1) IT1133025B (2)
MW (1) MW2380A1 (2)
OA (1) OA06699A (2)
ZA (1) ZA803880B (2)
ZM (1) ZM5780A1 (2)
ZW (1) ZW14480A1 (2)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193786B (it) * 1980-12-18 1988-08-24 Wellcome Found Composti eterei dotati di attivita' mitigatrice delle emoglobinopatie intermedi e procedimento per la loro preparazione
GB8606913D0 (en) * 1986-03-20 1986-04-23 Hider R C Treatment of sickle cell disease
AU6021598A (en) 1997-01-09 1998-08-03 Cohesion Technologies, Inc. Methods and apparatuses for making swellable uniformly shaped devices from polymeric materials
KR100788970B1 (ko) * 1999-11-05 2007-12-27 에미스페어 테크놀로지스, 인코포레이티드 활성제 전달용 페녹시 카르복시산 화합물 및 조성물
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
RU2300516C2 (ru) * 1999-11-05 2007-06-10 Эмисфере Текнолоджиз, Инк. Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ
AU2001245823A1 (en) * 2000-03-17 2001-10-03 Corixa Corporation Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors
US8246969B2 (en) 2001-11-16 2012-08-21 Skinmedica, Inc. Compositions containing aromatic aldehydes and their use in treatments
EP2661264B1 (en) 2011-01-07 2018-12-05 Allergan, Inc. Melanin modification compositions and methods of use
ES2643403T3 (es) 2011-12-28 2017-11-22 Global Blood Therapeutics, Inc. Compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular
HK1203412A1 (en) * 2011-12-28 2015-10-30 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
CN105073728A (zh) 2013-03-15 2015-11-18 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2014150258A1 (en) 2013-03-15 2014-09-25 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MX379235B (es) 2013-03-15 2025-03-11 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina.
WO2015027067A2 (en) * 2013-08-23 2015-02-26 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CN114181195A (zh) 2014-02-07 2022-03-15 全球血液疗法股份有限公司 一种化合物的结晶多晶型物
MX383691B (es) 2015-03-06 2025-03-14 Beyondspring Pharmaceuticals Inc Método de tratamiento de cáncer asociado con una mutación de ras.
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
SG11201804647TA (en) 2015-12-04 2018-06-28 Global Blood Therapeutics Inc Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
WO2017139231A1 (en) * 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
RU2760348C2 (ru) 2016-06-06 2021-11-24 Бейондспринг Фармасьютикалс, Инк. Способ уменьшения нейтропении
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
JP2020503363A (ja) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド チューブリン結合化合物およびその治療的使用
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
WO2019182938A1 (en) * 2018-03-22 2019-09-26 Virginia Commonwealth University Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin
PT3880654T (pt) 2018-11-19 2022-04-08 Global Blood Therapeutics Inc Compostos de 2-formil-3-hidroxifeniloximetil capazes de modular hemoglobina
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
CA3215047A1 (en) 2021-04-09 2022-10-13 Lan Huang Therapeutic compositions and methods for treating tumors
WO2024102304A1 (en) * 2022-11-07 2024-05-16 Virginia Commonwealth University Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL105100C (2) * 1958-04-30
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
CH550776A (de) 1971-03-05 1974-06-28 Ciba Geigy Ag Herstellung neuer bis-stilbenverbindungen.
DE2209128C3 (de) 1971-03-05 1981-10-22 CIBA-GEIGY AG, 4002 Basel Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
GB1511645A (en) 1974-05-31 1978-05-24 Univ Ife Sickle cell anaemia treatment
US4137309A (en) * 1976-10-14 1979-01-30 The Procter & Gamble Company Therapeutic treatment

Also Published As

Publication number Publication date
GB2053218B (en) 1984-01-25
IL60422A0 (en) 1980-09-16
KR830002693A (ko) 1983-05-30
FI71929B (fi) 1986-11-28
KR850000072B1 (ko) 1985-02-18
AU5969780A (en) 1981-01-08
ZA803880B (en) 1982-02-24
DK159770B (da) 1990-12-03
GB2053218A (en) 1981-02-04
HU190774B (en) 1986-11-28
KR850000073B1 (ko) 1985-02-18
OA06699A (fr) 1982-05-31
IT1133025B (it) 1986-07-09
GR68748B (2) 1982-02-16
KR840004668A (ko) 1984-10-22
JPH0154339B2 (2) 1989-11-17
MW2380A1 (en) 1982-03-10
FI71929C (fi) 1987-03-09
AU545274B2 (en) 1985-07-11
IL60422A (en) 1984-06-29
ZM5780A1 (en) 1983-11-21
DK159770C (da) 1991-04-22
FI802052A7 (fi) 1980-12-30
EP0022229B1 (en) 1982-12-08
JPS5649335A (en) 1981-05-02
EP0022229A1 (en) 1981-01-14
US4410537A (en) 1983-10-18
IT8049108A0 (it) 1980-06-27
DE3061269D1 (en) 1983-01-13
DK279780A (da) 1980-12-30

Similar Documents

Publication Publication Date Title
ZW14480A1 (en) Pharmaceutical ethers preparation use and intermediates therefore and their preparation
GB2055800B (en) Guanidinothiazoles and their preparation and use
ZA818741B (en) Pharmaceutical compounds,preparation,use and intermediates therefor and their preparation
ZA803567B (en) Pharmaceutical preparations
GB2065122B (en) Basic ethers their preparation and pharmaceutical compositions containing the same
IL60874A (en) Preparation of 4-fluoro-3-phenoxy-benzaldehyde,intermediates therefor and their preparation
NZ191709A (en) Naphtylmethyl-piperidines and pharmaceutical compostions intermediates
GB2052488B (en) 3 - vinyl - cephalosporins and their preparation
ZA804196B (en) Pharmaceutical formulations
JPS565207A (en) Tireeliner and its preparation
GB2051062B (en) 3-vinyl-cephalosporin derivatives and their preparation
JPS5422497A (en) Novel polyether compound* preparation thereof and use as pharmaceutical
GB2051794B (en) Hydroxyamino-eburnane derivatives their preparation and use pharmalceutical compositions containing them and intermediates therefor
DE3064789D1 (en) New 25-hydroxy-24-oxocholestane derivatives and preparation thereof
GB2010806A (en) Pyrindines and their preparation formulations and use
NZ193557A (en) 4-phenylchroman derivatives intermediates and pharmaceutical compositions
DE3071198D1 (en) Acridinones, their preparation and use; intermediates and their preparation
GB2048250B (en) 2-amino-6-aryl-4-pyrimidinols and their pharmaceutical uses
NZ192886A (en) Preparation of 7-acylindolin-2-ones and intermediates therein
DE3060100D1 (en) Omega-halogeno-acetophenone oxime ethers, preparation thereof and their use as intermediates in the preparation of omega-azolyl-acetophenone oxime ethers
ZW11780A1 (en) Novel pesticides preparation and use
EP0044954A3 (en) Anthracyclinglycosides, their preparation and intermediates, and pharmaceutical preparations
GB2009739B (en) A-40104 antibiotics their preparation use and formulations containing them
DE2962784D1 (en) Isoquinoline compounds, their preparation, pharmaceutical formulations containing them and intermediates
ZA783677B (en) Sulphonamide-containing pharmaceutical composition and preparation thereof