ZW9979A1 - Benzylpyrimidine compositions - Google Patents

Benzylpyrimidine compositions

Info

Publication number
ZW9979A1
ZW9979A1 ZW99/79A ZW9979A ZW9979A1 ZW 9979 A1 ZW9979 A1 ZW 9979A1 ZW 99/79 A ZW99/79 A ZW 99/79A ZW 9979 A ZW9979 A ZW 9979A ZW 9979 A1 ZW9979 A1 ZW 9979A1
Authority
ZW
Zimbabwe
Prior art keywords
benzylpyrimidine
compositions
benzylpyrimidine compositions
Prior art date
Application number
ZW99/79A
Other languages
English (en)
Inventor
Stanley Robert Morris Bushby
James Joseph Burchall
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZW9979A1 publication Critical patent/ZW9979A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZW99/79A 1978-05-24 1979-05-23 Benzylpyrimidine compositions ZW9979A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2193878 1978-05-24

Publications (1)

Publication Number Publication Date
ZW9979A1 true ZW9979A1 (en) 1980-12-24

Family

ID=10171323

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW99/79A ZW9979A1 (en) 1978-05-24 1979-05-23 Benzylpyrimidine compositions

Country Status (12)

Country Link
EP (1) EP0006987A1 (fr)
JP (1) JPS54154775A (fr)
AU (1) AU4732579A (fr)
DK (1) DK214479A (fr)
FI (1) FI791638A7 (fr)
IL (1) IL57375A0 (fr)
IT (1) IT1117752B (fr)
MA (1) MA18450A1 (fr)
MC (1) MC1264A1 (fr)
NO (1) NO791699L (fr)
PT (1) PT69656A (fr)
ZW (1) ZW9979A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054756B1 (fr) * 1980-11-27 1986-07-23 The Wellcome Foundation Limited Benzylpyrimidines antibactériennes
HU188588B (en) * 1982-08-13 1986-04-28 Egyt Gyogyszervegyeszeti Gyar Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives
FR2652812A1 (fr) * 1989-10-09 1991-04-12 Rhone Poulenc Chimie Procede de preparation de difluoro-2,2 benzodioxole-1,3.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB875562A (en) * 1957-02-21 1961-08-23 Wellcome Found Improvements in and relating to pyrimidine derivatives and the preparation thereof
GB1128234A (en) * 1966-02-19 1968-09-25 Wellcome Found 5-benzylpyrimidine derivatives and process for the preparation thereof
CH544053A (de) * 1966-05-09 1973-11-15 Hoffmann La Roche Verfahren zur Herstellung von Sulfonamidderivaten
US3684810A (en) * 1970-03-11 1972-08-15 Hoffmann La Roche Process for 2,4-diamino-5-(3,5-dimethoxy-4-hydroxybenzyl) pyrimidine
GB1375162A (fr) * 1970-10-22 1974-11-27
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
GB1413472A (en) * 1971-10-12 1975-11-12 Wellcome Found 2,4-diamino pyrimidines
DE2546667C3 (de) * 1975-10-17 1978-10-12 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-DiamüH»-5-(3-methoxy-4-hydroxy-5-halogenbenzyl)-pyrimidine, und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NO791699L (no) 1979-11-27
JPS54154775A (en) 1979-12-06
EP0006987A1 (fr) 1980-01-23
DK214479A (da) 1979-11-25
FI791638A7 (fi) 1979-11-25
IT7949150A0 (it) 1979-05-23
PT69656A (en) 1979-06-01
IT1117752B (it) 1986-02-24
IL57375A0 (en) 1979-09-30
AU4732579A (en) 1979-11-29
MC1264A1 (fr) 1980-03-28
MA18450A1 (fr) 1979-12-31

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