AP1882A - Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-Benzothiazole. - Google Patents

Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-Benzothiazole.

Info

Publication number: AP1882A
Authority: AP; ARIPO
Prior art keywords: benzothiazole; diamino; tetrahydro; preparing
Prior art date: 2002-11-04

Application number

AP2005003306A

Other languages

English (en)

Other versions

AP2005003306A0 (en

Inventor

Dharmaraj Ramachandra Rao

Rajendra Narayanrao Kankan

Original Assignee

Cipla Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-04

Filing date

2003-11-03

Publication date

2008-08-21

2003-11-03 Application filed by Cipla Ltd filed Critical Cipla Ltd

2005-06-30 Publication of AP2005003306A0 publication Critical patent/AP2005003306A0/xx

2008-08-21 Application granted granted Critical

2008-08-21 Publication of AP1882A publication Critical patent/AP1882A/xx

Links

DRRYZHHKWSHHFT-UHFFFAOYSA-N 4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine Chemical compound C1C(N)CCC2=C1SC(N)=N2 DRRYZHHKWSHHFT-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Thiazole And Isothizaole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

AP2005003306A 2002-11-04 2003-11-03 Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-Benzothiazole. AP1882A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0225701A GB2394951A (en)	2002-11-04	2002-11-04	One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole
PCT/GB2003/004734 WO2004041797A1 (en)	2002-11-04	2003-11-03	Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole

Publications (2)

Publication Number	Publication Date
AP2005003306A0 AP2005003306A0 (en)	2005-06-30
AP1882A true AP1882A (en)	2008-08-21

Family

ID=9947186

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2005003306A AP1882A (en)	2002-11-04	2003-11-03	Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-Benzothiazole.

Country Status (25)

Country	Link
US (1)	US7285669B2 (pl)
EP (1)	EP1562921B1 (pl)
JP (1)	JP4708792B2 (pl)
KR (1)	KR101086844B1 (pl)
CN (1)	CN100551918C (pl)
AP (1)	AP1882A (pl)
AT (1)	ATE396180T1 (pl)
AU (1)	AU2003278396B2 (pl)
BR (1)	BR0315919A (pl)
CA (1)	CA2505179C (pl)
DE (1)	DE60321208D1 (pl)
EC (1)	ECSP055835A (pl)
GB (1)	GB2394951A (pl)
HR (1)	HRPK20050403B3 (pl)
IS (1)	IS7882A (pl)
MA (1)	MA27534A1 (pl)
MX (1)	MXPA05004815A (pl)
NO (1)	NO20052189L (pl)
NZ (1)	NZ539953A (pl)
PL (1)	PL376543A1 (pl)
PT (1)	PT1562921E (pl)
RU (1)	RU2305097C2 (pl)
TN (1)	TNSN05125A1 (pl)
WO (1)	WO2004041797A1 (pl)
ZA (1)	ZA200503548B (pl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0221513D0 (en) *	2002-09-17	2002-10-23	Generics Uk Ltd	Novel compounds and processes
WO2006012277A2 (en) *	2004-06-30	2006-02-02	Amr Technology, Inc.	Biocatalytic process for preparing enantiomerically enriched pramipexole
US20070123573A1 (en) *	2004-07-01	2007-05-31	Alembic Limited	Process for the preparation of biologically active tetrahydrobenzthiazole derivative
US8518926B2 (en)	2006-04-10	2013-08-27	Knopp Neurosciences, Inc.	Compositions and methods of using (R)-pramipexole
PL2026803T3 (pl)	2006-05-16	2012-05-31	Knopp Neurosciences Inc	Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania
US8524695B2 (en)	2006-12-14	2013-09-03	Knopp Neurosciences, Inc.	Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
SI22446A (sl) *	2007-02-07	2008-08-31	Krka, Tovarna Zdravil, D.D., Novo Mesto	Nov postopek za sintezo pramipeksola in njegovih farmacevtsko sprejemljivih soli
WO2008104847A2 (en) *	2007-02-26	2008-09-04	Wockhardt Research Centre	Processes for the preparation of pramipexole and salts thereof
EP2137171A4 (en) *	2007-03-14	2010-05-19	Knopp Neurosciences Inc	SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE
CN101429173B (zh) *	2007-11-09	2012-12-05	重庆医药工业研究院有限责任公司	一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢-苯并噻唑的制备方法
US20110190356A1 (en)	2008-08-19	2011-08-04	Knopp Neurosciences Inc.	Compositions and Methods of Using (R)- Pramipexole
WO2011021214A2 (en) *	2009-08-07	2011-02-24	Msn Laboratories Limited	Improved process for the preparation of (s)-2-amino-4,5,6,7-tetrahydro-6 - (propylamino) benzothiazole and its pharmaceutically acceptable salts
US9512096B2 (en)	2011-12-22	2016-12-06	Knopp Biosciences, LLP	Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9662313B2 (en)	2013-02-28	2017-05-30	Knopp Biosciences Llc	Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en)	2013-07-12	2016-10-18	Knopp Biosciences Llc	Compositions and methods for treating conditions related to increased eosinophils
HRP20251187T1 (hr)	2013-07-12	2025-11-21	Areteia Therapeutics, Inc.	Liječenje povišenih razina eozinofila i/ili bazofila
US9642840B2 (en)	2013-08-13	2017-05-09	Knopp Biosciences, Llc	Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders
US9763918B2 (en)	2013-08-13	2017-09-19	Knopp Biosciences Llc	Compositions and methods for treating chronic urticaria
CN104311507A (zh) *	2013-10-09	2015-01-28	安徽万邦医药科技有限公司	(6s)-2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法
CN103613562B (zh) *	2013-11-25	2015-09-30	浙江美诺华药物化学有限公司	一种普拉克索的制备方法
CN107573301B (zh) *	2017-11-08	2020-08-11	江苏长青农化股份有限公司	一种三环唑中间体的制备方法
CN109232471B (zh) *	2018-10-31	2022-05-10	安徽省庆云医药股份有限公司	一种盐酸普拉克索的制备方法
CN111362884A (zh) *	2018-12-26	2020-07-03	江苏神龙药业股份有限公司	一种2,6-二氨基-4,5,6,7-四氢-苯并噻唑的工业化制备方法
CN110734413A (zh) *	2019-12-02	2020-01-31	山东铂源药业有限公司	一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0186087A1 (de) *	1984-12-22	1986-07-02	Dr. Karl Thomae GmbH	Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3447075A1 (de) *	1984-12-22	1986-07-03	Dr. Karl Thomae Gmbh, 7950 Biberach	Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE4241013A1 (de) *	1992-12-05	1994-06-09	Boehringer Ingelheim Kg	Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
ES2187249B1 (es) *	2000-09-18	2004-09-16	Synthon Bv	Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.

2002
- 2002-11-04 GB GB0225701A patent/GB2394951A/en not_active Withdrawn
2003
- 2003-11-03 EP EP03769701A patent/EP1562921B1/en not_active Expired - Lifetime
- 2003-11-03 DE DE60321208T patent/DE60321208D1/de not_active Expired - Lifetime
- 2003-11-03 PL PL376543A patent/PL376543A1/pl not_active IP Right Cessation
- 2003-11-03 PT PT03769701T patent/PT1562921E/pt unknown
- 2003-11-03 AP AP2005003306A patent/AP1882A/xx active
- 2003-11-03 BR BR0315919-1A patent/BR0315919A/pt not_active IP Right Cessation
- 2003-11-03 RU RU2005117364/04A patent/RU2305097C2/ru not_active IP Right Cessation
- 2003-11-03 WO PCT/GB2003/004734 patent/WO2004041797A1/en not_active Ceased
- 2003-11-03 MX MXPA05004815A patent/MXPA05004815A/es active IP Right Grant
- 2003-11-03 AU AU2003278396A patent/AU2003278396B2/en not_active Ceased
- 2003-11-03 HR HR20050403A patent/HRPK20050403B3/xx not_active IP Right Cessation
- 2003-11-03 JP JP2004549326A patent/JP4708792B2/ja not_active Expired - Fee Related
- 2003-11-03 AT AT03769701T patent/ATE396180T1/de not_active IP Right Cessation
- 2003-11-03 NZ NZ539953A patent/NZ539953A/en not_active IP Right Cessation
- 2003-11-03 KR KR1020057007963A patent/KR101086844B1/ko not_active Expired - Fee Related
- 2003-11-03 CN CNB2003801082013A patent/CN100551918C/zh not_active Expired - Fee Related
- 2003-11-03 CA CA2505179A patent/CA2505179C/en not_active Expired - Fee Related
- 2003-11-03 ZA ZA200503548A patent/ZA200503548B/en unknown
- 2003-11-03 US US10/533,637 patent/US7285669B2/en not_active Expired - Fee Related
2005
- 2005-05-04 NO NO20052189A patent/NO20052189L/no unknown
- 2005-05-04 TN TNP2005000125A patent/TNSN05125A1/en unknown
- 2005-06-02 MA MA28311A patent/MA27534A1/fr unknown
- 2005-06-02 IS IS7882A patent/IS7882A/is unknown
- 2005-06-03 EC EC2005005835A patent/ECSP055835A/es unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0186087A1 (de) *	1984-12-22	1986-07-02	Dr. Karl Thomae GmbH	Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 2, 1958, pages 64-74 *

Also Published As

Publication number	Publication date
PL376543A1 (pl)	2006-01-09
US7285669B2 (en)	2007-10-23
RU2005117364A (ru)	2006-02-27
AU2003278396B2 (en)	2010-04-01
JP4708792B2 (ja)	2011-06-22
HRPK20050403B3 (en)	2007-05-31
KR101086844B1 (ko)	2011-11-24
AU2003278396A1 (en)	2004-06-07
MA27534A1 (fr)	2005-09-01
AP2005003306A0 (en)	2005-06-30
CA2505179A1 (en)	2004-05-21
CN100551918C (zh)	2009-10-21
MXPA05004815A (es)	2005-08-18
NO20052189L (no)	2005-06-03
KR20050072474A (ko)	2005-07-11
US20060100256A1 (en)	2006-05-11
ATE396180T1 (de)	2008-06-15
GB2394951A (en)	2004-05-12
IS7882A (is)	2005-06-02
EP1562921A1 (en)	2005-08-17
CN1735604A (zh)	2006-02-15
ECSP055835A (es)	2005-11-22
CA2505179C (en)	2012-10-16
RU2305097C2 (ru)	2007-08-27
PT1562921E (pt)	2008-06-11
TNSN05125A1 (en)	2007-05-14
BR0315919A (pt)	2005-09-20
GB0225701D0 (en)	2002-12-11
JP2006506412A (ja)	2006-02-23
EP1562921B1 (en)	2008-05-21
NZ539953A (en)	2007-11-30
WO2004041797A1 (en)	2004-05-21
HRP20050403A2 (en)	2005-12-31
ZA200503548B (en)	2006-12-27
DE60321208D1 (de)	2008-07-03

Publication	Publication Date	Title
AP1882A (en)	2008-08-21	Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-Benzothiazole.
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MXPA03004826A (es)	2003-12-09	Articulos agricolas.
IL174919A0 (en)	2006-08-20	Diamine derivatives, process for the production thereof and plant disease control compositions containing the same
SI1555267T1 (sl)	2013-05-31	2,3-DIHIDRO-6-NITROIMIDAZO(2,1-b)OKSAZOLI
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PL376399A1 (pl)	2005-12-27	Nowe związki pirydopirymidynowe, proces ich wytwarzania i zawierające je mieszanki farmaceutyczne
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