AP2006003559A0 - Heteroaryl fused pyridines, pyrazines and pyrimidines as CRF 1 receptor ligands - Google Patents

Heteroaryl fused pyridines, pyrazines and pyrimidines as CRF 1 receptor ligands

Info

Publication number
AP2006003559A0
AP2006003559A0 AP2006003559A AP2006003559A AP2006003559A0 AP 2006003559 A0 AP2006003559 A0 AP 2006003559A0 AP 2006003559 A AP2006003559 A AP 2006003559A AP 2006003559 A AP2006003559 A AP 2006003559A AP 2006003559 A0 AP2006003559 A0 AP 2006003559A0
Authority
AP
ARIPO
Prior art keywords
pyrazines
crf
pyrimidines
receptor ligands
heteroaryl fused
Prior art date
Application number
AP2006003559A
Other languages
English (en)
Inventor
Ping Ge
Raymond F Horvath
Lu-Yan Zhang
Original Assignee
Neurogen Corp Ventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34272952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2006003559(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurogen Corp Ventis Pharmaceuticals Inc filed Critical Neurogen Corp Ventis Pharmaceuticals Inc
Publication of AP2006003559A0 publication Critical patent/AP2006003559A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AP2006003559A 2003-09-05 2004-09-03 Heteroaryl fused pyridines, pyrazines and pyrimidines as CRF 1 receptor ligands AP2006003559A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50041403P 2003-09-05 2003-09-05
PCT/US2004/028899 WO2005023806A2 (fr) 2003-09-05 2004-09-03 Pyridines, pyrazines et pyrimidines fusionnees avec heteroaryle utilisees comme ligands de recepteurs crf1

Publications (1)

Publication Number Publication Date
AP2006003559A0 true AP2006003559A0 (en) 2006-04-30

Family

ID=34272952

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003559A AP2006003559A0 (en) 2003-09-05 2004-09-03 Heteroaryl fused pyridines, pyrazines and pyrimidines as CRF 1 receptor ligands

Country Status (19)

Country Link
US (2) US20050113379A1 (fr)
EP (1) EP1680424A2 (fr)
JP (1) JP2007504271A (fr)
KR (1) KR20060088534A (fr)
CN (1) CN1878773A (fr)
AP (1) AP2006003559A0 (fr)
AR (1) AR045582A1 (fr)
AU (1) AU2004270713A1 (fr)
BR (1) BRPI0414087A (fr)
CA (1) CA2537829A1 (fr)
CR (1) CR8274A (fr)
EA (1) EA200600372A1 (fr)
EC (1) ECSP066408A (fr)
IL (1) IL174084A0 (fr)
MA (1) MA28086A1 (fr)
NO (1) NO20061180L (fr)
TW (1) TW200530232A (fr)
WO (1) WO2005023806A2 (fr)
ZA (1) ZA200601978B (fr)

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Also Published As

Publication number Publication date
WO2005023806A2 (fr) 2005-03-17
US20060199823A1 (en) 2006-09-07
ECSP066408A (es) 2006-09-18
KR20060088534A (ko) 2006-08-04
EA200600372A1 (ru) 2006-08-25
IL174084A0 (en) 2008-02-09
AU2004270713A1 (en) 2005-03-17
BRPI0414087A (pt) 2006-10-31
MA28086A1 (fr) 2006-08-01
CA2537829A1 (fr) 2005-03-17
CN1878773A (zh) 2006-12-13
EP1680424A2 (fr) 2006-07-19
CR8274A (es) 2008-06-10
TW200530232A (en) 2005-09-16
NO20061180L (no) 2006-03-31
JP2007504271A (ja) 2007-03-01
WO2005023806A3 (fr) 2005-06-02
ZA200601978B (en) 2007-05-30
US20050113379A1 (en) 2005-05-26
AR045582A1 (es) 2005-11-02

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