AP2008004656A0 - Substituted biphenyl carboxylic acids and derivatives thereof - Google Patents

Substituted biphenyl carboxylic acids and derivatives thereof

Info

Publication number: AP2008004656A0
Authority: AP; ARIPO
Prior art keywords: derivatives; carboxylic acids; substituted biphenyl; biphenyl carboxylic; substituted
Prior art date: 2006-04-21

Application number

AP2008004656A

Other languages

English (en)

Inventor

Jess Taylor

Francis Wilson

Yan Zhang

Original Assignee

Cellzome Ltd

Orthomcneil Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-21

Filing date

2007-04-20

Publication date

2008-10-31

2007-04-20 Application filed by Cellzome Ltd, Orthomcneil Pharmaceutical Inc filed Critical Cellzome Ltd

2008-10-31 Publication of AP2008004656A0 publication Critical patent/AP2008004656A0/xx

Links

ILYSAKHOYBPSPC-UHFFFAOYSA-N 2-phenylbenzoic acid Chemical class OC(=O)C1=CC=CC=C1C1=CC=CC=C1 ILYSAKHOYBPSPC-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AP2008004656A 2006-04-21 2007-04-20 Substituted biphenyl carboxylic acids and derivatives thereof AP2008004656A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06112938A EP1849762B1 (en)	2006-04-21	2006-04-21	Substituted biphenyl carboxylic acids and derivatives thereof
PCT/US2007/067039 WO2007124394A1 (en)	2006-04-21	2007-04-20	Substituted biphenyl carboxylic acids and derivatives thereof

Publications (1)

Publication Number	Publication Date
AP2008004656A0 true AP2008004656A0 (en)	2008-10-31

Family

ID=36688012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2008004656A AP2008004656A0 (en)	2006-04-21	2007-04-20	Substituted biphenyl carboxylic acids and derivatives thereof

Country Status (35)

Country	Link
US (1)	US7557244B2 (es)
EP (2)	EP1849762B1 (es)
JP (1)	JP5479088B2 (es)
KR (1)	KR101542255B1 (es)
CN (1)	CN101687758B (es)
AP (1)	AP2008004656A0 (es)
AR (1)	AR060568A1 (es)
AU (1)	AU2007240335B2 (es)
BR (1)	BRPI0710656A2 (es)
CA (1)	CA2650006C (es)
CR (2)	CR10375A (es)
CY (1)	CY1109399T1 (es)
DE (1)	DE602006007810D1 (es)
DK (1)	DK1849762T3 (es)
EA (1)	EA016129B9 (es)
ES (2)	ES2328616T3 (es)
GE (1)	GEP20115269B (es)
GT (1)	GT200900120A (es)
IL (2)	IL194852A0 (es)
MA (1)	MA30475B1 (es)
MX (1)	MX2008013445A (es)
MY (1)	MY148953A (es)
NO (1)	NO20084517L (es)
NZ (1)	NZ573000A (es)
PE (1)	PE20080364A1 (es)
PL (1)	PL1849762T3 (es)
PT (1)	PT1849762E (es)
SI (1)	SI1849762T1 (es)
SM (1)	SMP200800061B (es)
TN (1)	TNSN08413A1 (es)
TW (1)	TWI399362B (es)
UA (1)	UA95952C2 (es)
UY (1)	UY30301A1 (es)
WO (1)	WO2007124394A1 (es)
ZA (1)	ZA200809856B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20100081350A (ko) *	2007-10-19	2010-07-14	얀센 파마슈티카 엔.브이.	Ｇｓｍ 중간체
BRPI0818773A2 (pt)	2007-10-19	2015-04-14	Janssen Pharmaceutica Nv	Moduladores de gama-secretase ligados a carbono
AU2008312612B2 (en)	2007-10-19	2013-11-28	Janssen Pharmaceutica, N.V.	Piperidinyl and piperazinyl modulators of gamma-secretase
KR20100082351A (ko) *	2007-10-19	2010-07-16	얀센 파마슈티카 엔.브이.	γ-세크레타아제의 아민 결합된 조절제
WO2009067493A2 (en) *	2007-11-19	2009-05-28	Envivo Pharmaceuticals, Inc.	1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
US8217064B2 (en)	2007-12-20	2012-07-10	Envivo Pharmaceuticals, Inc.	Tetrasubstituted benzenes
EP2488031A4 (en)	2009-10-16	2014-07-23	Merck Sharp & Dohme	DIARYL ETHER DERIVATIVES AS A NOTCH-PROOFING GAMMETRETASE INHIBITOR
US8785481B2 (en)	2010-09-29	2014-07-22	Merck Sharp & Dohme Corp.	Ether benzotriazole derivatives
CA2828764A1 (en) *	2011-03-03	2012-09-07	Treventis Corporation	Anti-amyloid compounds and methods
WO2015109109A1 (en)	2014-01-15	2015-07-23	Forum Pharmaceuticals Inc.	Fused morpholinopyrimidines and methods of use thereof
WO2016201168A1 (en)	2015-06-10	2016-12-15	Forum Pharmceuticals Inc.	Oxadiazine compounds and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877399A (en) *	1994-01-27	1999-03-02	Johns Hopkins University	Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
JP3802581B2 (ja) *	1995-03-01	2006-07-26	富山化学工業株式会社	新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤
WO2001078721A1 (en)	2000-04-13	2001-10-25	Mayo Foundation For Medical Education And Research	Aβ42 LOWERING AGENTS
DE10131899A1 (de)	2001-07-04	2003-02-27	Boehringer Ingelheim Pharma	In vitro-Screening-Assay für gamma-Secretase
NZ537206A (en) *	2002-06-27	2007-06-29	Astellas Pharma Inc	Aminoalcohol derivatives
GB0305918D0 (en) *	2003-03-14	2003-04-23	Glaxo Group Ltd	Novel compounds
WO2005110963A1 (en) *	2004-05-19	2005-11-24	Cellzome Ag	(biphenyl-3-yl)-carboxylic acids and derivatives thereof and their use in therapy
GB0416508D0 (en) *	2004-07-23	2004-08-25	Merck Sharp & Dohme	Therapeutic agents
TW200621227A (en) *	2004-08-24	2006-07-01	Kissei Pharmaceutical	Medicament for preventing or treating fatty liver
JP5155171B2 (ja) *	2005-10-06	2013-02-27	アストラゼネカ・アクチエボラーグ	新規化合物

2006
- 2006-04-21 EP EP06112938A patent/EP1849762B1/en not_active Not-in-force
- 2006-04-21 ES ES06112938T patent/ES2328616T3/es active Active
- 2006-04-21 SI SI200630391T patent/SI1849762T1/sl unknown
- 2006-04-21 PL PL06112938T patent/PL1849762T3/pl unknown
- 2006-04-21 DE DE602006007810T patent/DE602006007810D1/de active Active
- 2006-04-21 DK DK06112938T patent/DK1849762T3/da active
- 2006-04-21 PT PT06112938T patent/PT1849762E/pt unknown
2007
- 2007-04-20 NZ NZ573000A patent/NZ573000A/en not_active IP Right Cessation
- 2007-04-20 EP EP07760976A patent/EP2021314B1/en active Active
- 2007-04-20 ES ES07760976T patent/ES2400530T3/es active Active
- 2007-04-20 AR ARP070101725A patent/AR060568A1/es not_active Application Discontinuation
- 2007-04-20 SM SM200800061T patent/SMP200800061B/it unknown
- 2007-04-20 UY UY30301A patent/UY30301A1/es unknown
- 2007-04-20 AP AP2008004656A patent/AP2008004656A0/xx unknown
- 2007-04-20 AU AU2007240335A patent/AU2007240335B2/en not_active Ceased
- 2007-04-20 CN CN200780018586.2A patent/CN101687758B/zh not_active Expired - Fee Related
- 2007-04-20 GE GEAP200710983A patent/GEP20115269B/en unknown
- 2007-04-20 WO PCT/US2007/067039 patent/WO2007124394A1/en not_active Ceased
- 2007-04-20 KR KR1020087028566A patent/KR101542255B1/ko not_active Expired - Fee Related
- 2007-04-20 PE PE2007000496A patent/PE20080364A1/es active IP Right Grant
- 2007-04-20 MY MYPI20084201A patent/MY148953A/en unknown
- 2007-04-20 US US11/737,938 patent/US7557244B2/en not_active Expired - Fee Related
- 2007-04-20 EA EA200802172A patent/EA016129B9/ru not_active IP Right Cessation
- 2007-04-20 TW TW096114160A patent/TWI399362B/zh not_active IP Right Cessation
- 2007-04-20 BR BRPI0710656-4A patent/BRPI0710656A2/pt not_active IP Right Cessation
- 2007-04-20 UA UAA200813476A patent/UA95952C2/ru unknown
- 2007-04-20 CA CA2650006A patent/CA2650006C/en not_active Expired - Fee Related
- 2007-04-20 MX MX2008013445A patent/MX2008013445A/es active IP Right Grant
- 2007-04-20 JP JP2009506782A patent/JP5479088B2/ja not_active Expired - Fee Related
2008
- 2008-10-17 CR CR10375A patent/CR10375A/es not_active Application Discontinuation
- 2008-10-17 TN TNP2008000413A patent/TNSN08413A1/en unknown
- 2008-10-22 IL IL194852A patent/IL194852A0/en unknown
- 2008-10-22 IL IL194790A patent/IL194790A/en not_active IP Right Cessation
- 2008-10-27 NO NO20084517A patent/NO20084517L/no not_active Application Discontinuation
- 2008-11-19 ZA ZA200809856A patent/ZA200809856B/xx unknown
- 2008-11-20 MA MA31395A patent/MA30475B1/fr unknown
- 2008-11-21 CR CR10451A patent/CR10451A/es not_active Application Discontinuation
2009
- 2009-05-11 GT GT200900120A patent/GT200900120A/es unknown
- 2009-09-21 CY CY20091100982T patent/CY1109399T1/el unknown

Also Published As

Publication number	Publication date
SI1849762T1 (sl)	2009-12-31
TNSN08413A1 (en)	2010-04-14
AR060568A1 (es)	2008-06-25
CA2650006A1 (en)	2007-11-01
EP2021314A1 (en)	2009-02-11
PE20080364A1 (es)	2008-05-16
ES2400530T3 (es)	2013-04-10
WO2007124394A1 (en)	2007-11-01
TW200815320A (en)	2008-04-01
ES2328616T3 (es)	2009-11-16
DE602006007810D1 (de)	2009-08-27
EP1849762B1 (en)	2009-07-15
CN101687758B (zh)	2014-05-14
CR10451A (es)	2009-03-31
EA016129B9 (ru)	2012-06-29
AU2007240335A1 (en)	2007-11-01
BRPI0710656A2 (pt)	2011-08-16
EP2021314B1 (en)	2013-01-23
NO20084517L (no)	2009-01-13
US7557244B2 (en)	2009-07-07
IL194790A (en)	2012-12-31
PL1849762T3 (pl)	2009-12-31
UY30301A1 (es)	2007-08-31
DK1849762T3 (da)	2009-10-12
CA2650006C (en)	2016-08-23
US20070293567A1 (en)	2007-12-20
CY1109399T1 (el)	2014-07-02
KR101542255B1 (ko)	2015-08-06
EA200802172A1 (ru)	2009-06-30
AU2007240335B2 (en)	2013-05-02
KR20090024679A (ko)	2009-03-09
GEP20115269B (en)	2011-08-25
GT200900120A (es)	2009-11-16
SMP200800061B (it)	2009-07-14
TWI399362B (zh)	2013-06-21
ZA200809856B (en)	2009-06-24
SMAP200800061A (it)	2008-11-19
EP1849762A1 (en)	2007-10-31
NZ573000A (en)	2011-11-25
JP2009544573A (ja)	2009-12-17
PT1849762E (pt)	2009-09-16
CR10375A (es)	2009-02-26
UA95952C2 (ru)	2011-09-26
MX2008013445A (es)	2009-03-10
IL194852A0 (en)	2009-08-03
EA016129B1 (ru)	2012-02-28
IL194790A0 (en)	2009-08-03
CN101687758A (zh)	2010-03-31
MA30475B1 (fr)	2009-06-01
JP5479088B2 (ja)	2014-04-23
MY148953A (en)	2013-06-14

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IL192846A0 (en)	2009-02-11	Anthranilamide/2-amino-heteroarene carboxamide derivatives
NO20084762L (no)	2009-01-06	Process for the preparation of carboxylic acids and/or derivates thereof
ZA200800348B (en)	2009-01-28	Derivatives of seleno-amino acids
ZA201003432B (en)	2012-07-25	Biphenyl carboxylic acids and derivatives thereof
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ZA200703258B (en)	2009-04-29	(Biphenyl) carboxylic acids and derivatives thereof
GB0605195D0 (en)	2006-04-26	Starbon acids
ZA200704358B (en)	2008-09-25	Biaryloxymethylarene carboxylic acids
AP2006003847A0 (en)	2006-12-31	Benzhimidazolone carboxylic acid derivatives
AU311019S (en)	2006-10-27	Tagging spike