AP3048A - Agomelatine hydrohalide complex and preparation method thereof - Google Patents

Agomelatine hydrohalide complex and preparation method thereof

Info

Publication number: AP3048A
Authority: AP; ARIPO
Prior art keywords: preparation; agomelatine; complex; hydrohalide complex; agomelatine hydrohalide
Prior art date: 2009-02-27

Application number

AP2011005845A

Other languages

English (en)

Other versions

AP2011005845A0 (en

Inventor

Peng Zhang

Hanbin Shan

Zhedong Yuan

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-02-27

Filing date

2010-02-26

Publication date

2014-11-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40878634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3048(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-02-26 Application filed by Servier Lab filed Critical Servier Lab

2011-08-31 Publication of AP2011005845A0 publication Critical patent/AP2011005845A0/xx

2014-11-30 Application granted granted Critical

2014-11-30 Publication of AP3048A publication Critical patent/AP3048A/xx

Links

YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title 1
229960002629 agomelatine Drugs 0.000 title 1
238000010668 complexation reaction Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B7/00—Halogens; Halogen acids
- C01B7/01—Chlorine; Hydrogen chloride
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B7/00—Halogens; Halogen acids
- C01B7/09—Bromine; Hydrogen bromide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AP2011005845A 2009-02-27 2010-02-26 Agomelatine hydrohalide complex and preparation method thereof AP3048A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CN2009100467821A CN101481321B (zh)	2009-02-27	2009-02-27	阿戈美拉汀卤化氢复合物及其制备方法
PCT/CN2010/070780 WO2010097052A1 (fr)	2009-02-27	2010-02-26	Complexe d'hydrohalogénure d'agomélatine et procédé de préparation de celui-ci

Publications (2)

Publication Number	Publication Date
AP2011005845A0 AP2011005845A0 (en)	2011-08-31
AP3048A true AP3048A (en)	2014-11-30

Family

ID=40878634

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2011005845A AP3048A (en)	2009-02-27	2010-02-26	Agomelatine hydrohalide complex and preparation method thereof

Country Status (36)

Country	Link
US (1)	US8524949B2 (fr)
EP (1)	EP2418195B1 (fr)
JP (1)	JP5426693B2 (fr)
KR (1)	KR101284202B1 (fr)
CN (1)	CN101481321B (fr)
AP (1)	AP3048A (fr)
AU (1)	AU2010217082B2 (fr)
BR (1)	BRPI1008767B1 (fr)
CA (1)	CA2753449C (fr)
CL (1)	CL2011002090A1 (fr)
CO (1)	CO6420335A2 (fr)
CR (1)	CR20110446A (fr)
CU (1)	CU20110163A7 (fr)
CY (1)	CY1117100T1 (fr)
DK (1)	DK2418195T3 (fr)
EA (1)	EA021939B1 (fr)
EC (1)	ECSP11011290A (fr)
ES (1)	ES2530730T3 (fr)
GE (1)	GEP20156221B (fr)
HN (1)	HN2011002291A (fr)
HR (1)	HRP20150072T1 (fr)
IL (1)	IL214682A (fr)
MA (1)	MA33063B1 (fr)
MX (1)	MX2011008946A (fr)
MY (1)	MY154015A (fr)
NI (1)	NI201100163A (fr)
NZ (1)	NZ594773A (fr)
PE (1)	PE20120652A1 (fr)
PL (1)	PL2418195T3 (fr)
PT (1)	PT2418195E (fr)
RS (1)	RS53751B1 (fr)
SG (1)	SG173691A1 (fr)
SI (1)	SI2418195T1 (fr)
UA (1)	UA97619C2 (fr)
WO (1)	WO2010097052A1 (fr)
ZA (1)	ZA201106048B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102106806B (zh) *	2009-12-29	2013-04-17	上海中西制药有限公司	一种固体制剂的制备方法及所得固体制剂
CN102190594A (zh) *	2010-03-17	2011-09-21	上海医药工业研究院	阿戈美拉汀氯化氢水合物及其制备方法
CN102190595A (zh) *	2010-03-17	2011-09-21	上海医药工业研究院	阿戈美拉汀溴化氢水合物及其制备方法
CN101870662B (zh) *	2010-05-21	2013-03-20	中山大学	结晶型阿戈美拉汀溶剂化物及其制备方法
WO2012046253A2 (fr) *	2010-10-08	2012-04-12	Msn Laboratories Limited	Procédé de préparation de n-[2- (7-méthoxy-l-naphthyl) éthyl] acétamide et ses nouvelles formes cristallines
RS52982B (sr) *	2011-04-28	2014-02-28	Zentiva, K.S.	Farmaceutski prihvatljivi kokristali n-[2-(7-metoksi-1-naftil]acetamida i postupci njihove izrade
EP2551257A1 (fr) *	2011-07-28	2013-01-30	Laboratorios Del. Dr. Esteve, S.A.	Co-cristaux d'agomélatine avec formeurs de co-cristaux
FR2978916B1 (fr)	2011-08-10	2013-07-26	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
EP2851363B1 (fr) *	2012-05-14	2018-01-03	Shanghai Righthand Pharmtech. Co., Ltd.	Composite à base de radical acide d'agomélatine et procédé de préparation et application associés
CN102702041B (zh) *	2012-05-14	2013-08-14	上海右手医药科技开发有限公司	阿戈美拉汀苯磺酸类复合物及其制备方法
CN102718675B (zh) *	2012-06-07	2015-03-25	上海右手医药科技开发有限公司	阿戈美拉汀甲磺酸复合物及其制备方法
CN102702008B (zh) *	2012-06-03	2014-05-28	上海右手医药科技开发有限公司	阿戈美拉汀硫酸复合物及其制备方法
ES2590908T3 (es) *	2012-12-17	2016-11-24	Dr. Reddy's Laboratories Ltd.	Cocristal de agomelatina con ácido fosfórico
WO2014096373A1 (fr)	2012-12-21	2014-06-26	Laboratorios Lesvi, S. L.	Procédé de préparation de n-(2-(7-méthoxy-1-naphtalényl)éthyl)acétamide et de formes solides de celui-ci
FR3001894A1 (fr)	2013-02-08	2014-08-15	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
HK1223088A1 (zh) *	2013-07-29	2017-07-21	Les Laboratoires Servier	阿戈美拉汀和磺酸的新复合物、其制备方法和包含其的药物组合物
ES2734562T3 (es) *	2013-07-31	2019-12-10	Servier Lab	Co-cristales de agomelatina y ácido p-toluensulfónico, su procedimiento de preparación y composiciones farmacéuticas que los contienen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050182276A1 (en) *	2004-02-13	2005-08-18	Jean-Claude Souvie	Process for the synthesis and crystalline form of agomelatine
CN1907958A (zh) *	2005-08-03	2007-02-07	瑟维尔实验室	阿戈美拉汀的新晶形ⅴ、它的制备方法和包含它的药物组合物
EP1752440A1 (fr) *	2004-01-15	2007-02-14	Tosoh Corporation	Compose amine comprenant un groupe fluorene en tant que structure, procede de production dudit compose amine, et utilisation de ce dernier

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2658818B1 (fr) *	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2778662B1 (fr) *	1998-05-12	2000-06-16	Adir	Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795326B1 (fr) *	1999-06-28	2001-08-31	Adir	Composition pharmaceutique solide thermoformable a liberation controlee
DK1511724T3 (da)	2002-05-24	2014-06-16	Bayer Cropscience Ag	Fremgangsmåde til fremstilling af thioalkylaminderivater
FR2899472B1 (fr) *	2006-04-07	2008-09-12	Servier Lab	Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee

2009
- 2009-02-27 CN CN2009100467821A patent/CN101481321B/zh not_active Expired - Fee Related
2010
- 2010-02-26 DK DK10745836T patent/DK2418195T3/en active
- 2010-02-26 US US13/138,511 patent/US8524949B2/en not_active Expired - Fee Related
- 2010-02-26 EA EA201101208A patent/EA021939B1/ru unknown
- 2010-02-26 PT PT107458366T patent/PT2418195E/pt unknown
- 2010-02-26 MY MYPI2011003884A patent/MY154015A/en unknown
- 2010-02-26 JP JP2011551399A patent/JP5426693B2/ja not_active Expired - Fee Related
- 2010-02-26 ES ES10745836T patent/ES2530730T3/es active Active
- 2010-02-26 UA UAA201111232A patent/UA97619C2/ru unknown
- 2010-02-26 KR KR1020117021812A patent/KR101284202B1/ko not_active Expired - Fee Related
- 2010-02-26 EP EP10745836.6A patent/EP2418195B1/fr active Active
- 2010-02-26 BR BRPI1008767-2A patent/BRPI1008767B1/pt not_active IP Right Cessation
- 2010-02-26 HR HRP20150072AT patent/HRP20150072T1/hr unknown
- 2010-02-26 WO PCT/CN2010/070780 patent/WO2010097052A1/fr not_active Ceased
- 2010-02-26 PL PL10745836T patent/PL2418195T3/pl unknown
- 2010-02-26 MA MA34120A patent/MA33063B1/fr unknown
- 2010-02-26 AP AP2011005845A patent/AP3048A/xx active
- 2010-02-26 GE GEAP201012388A patent/GEP20156221B/en unknown
- 2010-02-26 CA CA2753449A patent/CA2753449C/fr active Active
- 2010-02-26 PE PE2011001512A patent/PE20120652A1/es not_active Application Discontinuation
- 2010-02-26 MX MX2011008946A patent/MX2011008946A/es active IP Right Grant
- 2010-02-26 SI SI201030872T patent/SI2418195T1/sl unknown
- 2010-02-26 AU AU2010217082A patent/AU2010217082B2/en not_active Ceased
- 2010-02-26 SG SG2011058542A patent/SG173691A1/en unknown
- 2010-02-26 RS RS20150040A patent/RS53751B1/sr unknown
- 2010-02-26 NZ NZ594773A patent/NZ594773A/xx not_active IP Right Cessation
2011
- 2011-08-16 IL IL214682A patent/IL214682A/en active IP Right Grant
- 2011-08-17 ZA ZA2011/06048A patent/ZA201106048B/en unknown
- 2011-08-19 CR CR20110446A patent/CR20110446A/es unknown
- 2011-08-23 CU CU20110163A patent/CU20110163A7/es unknown
- 2011-08-26 NI NI201100163A patent/NI201100163A/es unknown
- 2011-08-26 CO CO11109274A patent/CO6420335A2/es not_active Application Discontinuation
- 2011-08-26 HN HN2011002291A patent/HN2011002291A/es unknown
- 2011-08-26 EC EC2011011290A patent/ECSP11011290A/es unknown
- 2011-08-26 CL CL2011002090A patent/CL2011002090A1/es unknown
2015
- 2015-01-22 CY CY20151100070T patent/CY1117100T1/el unknown

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1752440A1 (fr) *	2004-01-15	2007-02-14	Tosoh Corporation	Compose amine comprenant un groupe fluorene en tant que structure, procede de production dudit compose amine, et utilisation de ce dernier
US20050182276A1 (en) *	2004-02-13	2005-08-18	Jean-Claude Souvie	Process for the synthesis and crystalline form of agomelatine
CN1907958A (zh) *	2005-08-03	2007-02-07	瑟维尔实验室	阿戈美拉汀的新晶形ⅴ、它的制备方法和包含它的药物组合物

Also Published As

Publication number	Publication date
US20110313198A1 (en)	2011-12-22
IL214682A0 (en)	2011-11-30
UA97619C2 (ru)	2012-02-27
SI2418195T1 (sl)	2015-03-31
CO6420335A2 (es)	2012-04-16
MX2011008946A (es)	2011-09-27
EA021939B1 (ru)	2015-10-30
US8524949B2 (en)	2013-09-03
CN101481321A (zh)	2009-07-15
AU2010217082A1 (en)	2011-09-08
CL2011002090A1 (es)	2012-02-03
DK2418195T3 (en)	2015-03-02
ECSP11011290A (es)	2011-09-30
HN2011002291A (es)	2014-04-07
CY1117100T1 (el)	2017-04-05
PT2418195E (pt)	2014-12-26
MA33063B1 (fr)	2012-02-01
IL214682A (en)	2015-10-29
BRPI1008767B1 (pt)	2021-06-15
SG173691A1 (en)	2011-09-29
CA2753449A1 (fr)	2010-09-02
AP2011005845A0 (en)	2011-08-31
CN101481321B (zh)	2012-04-18
EP2418195A4 (fr)	2013-01-16
KR20110117721A (ko)	2011-10-27
CU20110163A7 (es)	2012-02-15
NI201100163A (es)	2011-12-12
JP2012519155A (ja)	2012-08-23
ZA201106048B (en)	2012-10-31
CR20110446A (es)	2011-10-18
AU2010217082B2 (en)	2012-05-03
PE20120652A1 (es)	2012-06-14
GEP20156221B (en)	2015-01-26
NZ594773A (en)	2013-03-28
EA201101208A1 (ru)	2012-04-30
EP2418195B1 (fr)	2014-11-19
CA2753449C (fr)	2014-01-07
BRPI1008767A2 (pt)	2016-06-28
EP2418195A1 (fr)	2012-02-15
HRP20150072T1 (xx)	2015-03-13
WO2010097052A1 (fr)	2010-09-02
PL2418195T3 (pl)	2015-04-30
RS53751B1 (sr)	2015-06-30
ES2530730T3 (es)	2015-03-05
JP5426693B2 (ja)	2014-02-26
MY154015A (en)	2015-04-30
KR101284202B1 (ko)	2013-07-09

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