MA33063B1 - Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci - Google Patents

Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci

Info

Publication number
MA33063B1
MA33063B1 MA34120A MA34120A MA33063B1 MA 33063 B1 MA33063 B1 MA 33063B1 MA 34120 A MA34120 A MA 34120A MA 34120 A MA34120 A MA 34120A MA 33063 B1 MA33063 B1 MA 33063B1
Authority
MA
Morocco
Prior art keywords
hydrohalogenide
agomelatin
preparing
complex
same
Prior art date
Application number
MA34120A
Other languages
Arabic (ar)
English (en)
Inventor
Peng Zhang
Hanbin Shan
Zhedong Yuan
Xudong Jiang
Yu Huang
Hubo Wang
Xufeng Cao
Xingdong Cheng
Hongjuan Pan
Xiong Yu
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40878634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33063(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of MA33063B1 publication Critical patent/MA33063B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/01—Chlorine; Hydrogen chloride
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/09—Bromine; Hydrogen bromide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UN COMPLEXE D'HYDROHALOGÉNURE D'AGOMÉLATINE ET UN PROCÉDÉ DE PRÉPARATION DE CELUI-CI. COMPARÉ À L'AGOMÉLATINE, UN COMPLEXE D'HYDROHALOGÉNURE D'AGOMÉLATINE OBTENU PAR LE PRÉSENT PROCÉDÉ A UNE SOLUBILITÉ AMÉLIORÉE, ET EST ADAPTÉ À L'APPLICATION NÉCESSAIRE DE PRÉPARATION DE PRODUITS FINIS DE MÉDICAMENTS. DE PLUS, LE PRODUIT A UNE BONNE STABILITÉ ET UNE PURETÉ ÉLEVÉE. LE PROCÉDÉ DE PRÉPARATION EST SIMPLE ET COMMODE ET LE PRODUIT AYANT UNE PURETÉ ÉLEVÉ PEUT ÊTRE OBTENU SANS OPÉRATIONS SPÉCIALES.
MA34120A 2009-02-27 2010-02-26 Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci MA33063B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2009100467821A CN101481321B (zh) 2009-02-27 2009-02-27 阿戈美拉汀卤化氢复合物及其制备方法
PCT/CN2010/070780 WO2010097052A1 (fr) 2009-02-27 2010-02-26 Complexe d'hydrohalogénure d'agomélatine et procédé de préparation de celui-ci

Publications (1)

Publication Number Publication Date
MA33063B1 true MA33063B1 (fr) 2012-02-01

Family

ID=40878634

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34120A MA33063B1 (fr) 2009-02-27 2010-02-26 Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci

Country Status (36)

Country Link
US (1) US8524949B2 (fr)
EP (1) EP2418195B1 (fr)
JP (1) JP5426693B2 (fr)
KR (1) KR101284202B1 (fr)
CN (1) CN101481321B (fr)
AP (1) AP3048A (fr)
AU (1) AU2010217082B2 (fr)
BR (1) BRPI1008767B1 (fr)
CA (1) CA2753449C (fr)
CL (1) CL2011002090A1 (fr)
CO (1) CO6420335A2 (fr)
CR (1) CR20110446A (fr)
CU (1) CU20110163A7 (fr)
CY (1) CY1117100T1 (fr)
DK (1) DK2418195T3 (fr)
EA (1) EA021939B1 (fr)
EC (1) ECSP11011290A (fr)
ES (1) ES2530730T3 (fr)
GE (1) GEP20156221B (fr)
HN (1) HN2011002291A (fr)
HR (1) HRP20150072T1 (fr)
IL (1) IL214682A (fr)
MA (1) MA33063B1 (fr)
MX (1) MX2011008946A (fr)
MY (1) MY154015A (fr)
NI (1) NI201100163A (fr)
NZ (1) NZ594773A (fr)
PE (1) PE20120652A1 (fr)
PL (1) PL2418195T3 (fr)
PT (1) PT2418195E (fr)
RS (1) RS53751B1 (fr)
SG (1) SG173691A1 (fr)
SI (1) SI2418195T1 (fr)
UA (1) UA97619C2 (fr)
WO (1) WO2010097052A1 (fr)
ZA (1) ZA201106048B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106806B (zh) * 2009-12-29 2013-04-17 上海中西制药有限公司 一种固体制剂的制备方法及所得固体制剂
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CN101870662B (zh) * 2010-05-21 2013-03-20 中山大学 结晶型阿戈美拉汀溶剂化物及其制备方法
WO2012046253A2 (fr) * 2010-10-08 2012-04-12 Msn Laboratories Limited Procédé de préparation de n-[2- (7-méthoxy-l-naphthyl) éthyl] acétamide et ses nouvelles formes cristallines
RS52982B (sr) * 2011-04-28 2014-02-28 Zentiva, K.S. Farmaceutski prihvatljivi kokristali n-[2-(7-metoksi-1-naftil]acetamida i postupci njihove izrade
EP2551257A1 (fr) * 2011-07-28 2013-01-30 Laboratorios Del. Dr. Esteve, S.A. Co-cristaux d'agomélatine avec formeurs de co-cristaux
FR2978916B1 (fr) 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
EP2851363B1 (fr) * 2012-05-14 2018-01-03 Shanghai Righthand Pharmtech. Co., Ltd. Composite à base de radical acide d'agomélatine et procédé de préparation et application associés
CN102702041B (zh) * 2012-05-14 2013-08-14 上海右手医药科技开发有限公司 阿戈美拉汀苯磺酸类复合物及其制备方法
CN102718675B (zh) * 2012-06-07 2015-03-25 上海右手医药科技开发有限公司 阿戈美拉汀甲磺酸复合物及其制备方法
CN102702008B (zh) * 2012-06-03 2014-05-28 上海右手医药科技开发有限公司 阿戈美拉汀硫酸复合物及其制备方法
ES2590908T3 (es) * 2012-12-17 2016-11-24 Dr. Reddy's Laboratories Ltd. Cocristal de agomelatina con ácido fosfórico
WO2014096373A1 (fr) 2012-12-21 2014-06-26 Laboratorios Lesvi, S. L. Procédé de préparation de n-(2-(7-méthoxy-1-naphtalényl)éthyl)acétamide et de formes solides de celui-ci
FR3001894A1 (fr) 2013-02-08 2014-08-15 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
HK1223088A1 (zh) * 2013-07-29 2017-07-21 Les Laboratoires Servier 阿戈美拉汀和磺酸的新复合物、其制备方法和包含其的药物组合物
ES2734562T3 (es) * 2013-07-31 2019-12-10 Servier Lab Co-cristales de agomelatina y ácido p-toluensulfónico, su procedimiento de preparación y composiciones farmacéuticas que los contienen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795326B1 (fr) * 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee
DK1511724T3 (da) 2002-05-24 2014-06-16 Bayer Cropscience Ag Fremgangsmåde til fremstilling af thioalkylaminderivater
TW200533634A (en) * 2004-01-15 2005-10-16 Tosoh Corp Amine compound having fluorine group as framework, process for producing the amine compound, and use of the amine compound
FR2866335B1 (fr) 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
FR2889523B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2899472B1 (fr) * 2006-04-07 2008-09-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee

Also Published As

Publication number Publication date
US20110313198A1 (en) 2011-12-22
AP3048A (en) 2014-11-30
IL214682A0 (en) 2011-11-30
UA97619C2 (ru) 2012-02-27
SI2418195T1 (sl) 2015-03-31
CO6420335A2 (es) 2012-04-16
MX2011008946A (es) 2011-09-27
EA021939B1 (ru) 2015-10-30
US8524949B2 (en) 2013-09-03
CN101481321A (zh) 2009-07-15
AU2010217082A1 (en) 2011-09-08
CL2011002090A1 (es) 2012-02-03
DK2418195T3 (en) 2015-03-02
ECSP11011290A (es) 2011-09-30
HN2011002291A (es) 2014-04-07
CY1117100T1 (el) 2017-04-05
PT2418195E (pt) 2014-12-26
IL214682A (en) 2015-10-29
BRPI1008767B1 (pt) 2021-06-15
SG173691A1 (en) 2011-09-29
CA2753449A1 (fr) 2010-09-02
AP2011005845A0 (en) 2011-08-31
CN101481321B (zh) 2012-04-18
EP2418195A4 (fr) 2013-01-16
KR20110117721A (ko) 2011-10-27
CU20110163A7 (es) 2012-02-15
NI201100163A (es) 2011-12-12
JP2012519155A (ja) 2012-08-23
ZA201106048B (en) 2012-10-31
CR20110446A (es) 2011-10-18
AU2010217082B2 (en) 2012-05-03
PE20120652A1 (es) 2012-06-14
GEP20156221B (en) 2015-01-26
NZ594773A (en) 2013-03-28
EA201101208A1 (ru) 2012-04-30
EP2418195B1 (fr) 2014-11-19
CA2753449C (fr) 2014-01-07
BRPI1008767A2 (pt) 2016-06-28
EP2418195A1 (fr) 2012-02-15
HRP20150072T1 (xx) 2015-03-13
WO2010097052A1 (fr) 2010-09-02
PL2418195T3 (pl) 2015-04-30
RS53751B1 (sr) 2015-06-30
ES2530730T3 (es) 2015-03-05
JP5426693B2 (ja) 2014-02-26
MY154015A (en) 2015-04-30
KR101284202B1 (ko) 2013-07-09

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