AP370A - Process for the preparation of substituted steroidal dienes. - Google Patents

Process for the preparation of substituted steroidal dienes. Download PDF

Info

Publication number: AP370A
Authority: AP; ARIPO
Prior art keywords: reagent; process according; chloride; vilsmeier reagent; source
Prior art date: 1992-01-06

Application number

APAP/P/1993/000473A

Other languages

English (en)

Other versions

AP9300473A0 (en

Inventor

Neil Howard Baine

Donald Nathaniel Kline

Richard Eric Mewshaw

Franklin Owings

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-06

Filing date

1993-01-05

Publication date

1994-11-10

1993-01-05 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1993-01-31 Publication of AP9300473A0 publication Critical patent/AP9300473A0/xx

1994-11-10 Application granted granted Critical

1994-11-10 Publication of AP370A publication Critical patent/AP370A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

APAP/P/1993/000473A 1992-01-06 1993-01-05 Process for the preparation of substituted steroidal dienes. AP370A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US81717992A	1992-01-06	1992-01-06
US94134892A	1992-09-04	1992-09-04

Publications (2)

Publication Number	Publication Date
AP9300473A0 AP9300473A0 (en)	1993-01-31
AP370A true AP370A (en)	1994-11-10

Family

ID=27124147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/1993/000473A AP370A (en)	1992-01-06	1993-01-05	Process for the preparation of substituted steroidal dienes.

Country Status (23)

Country	Link
EP (1)	EP0643723A4 (fr)
JP (1)	JPH07505138A (fr)
KR (1)	KR940703849A (fr)
CN (1)	CN1077201A (fr)
AP (1)	AP370A (fr)
AU (1)	AU666167B2 (fr)
BG (1)	BG98887A (fr)
BR (1)	BR9305786A (fr)
CA (1)	CA2127272A1 (fr)
CZ (1)	CZ161994A3 (fr)
FI (1)	FI943214A0 (fr)
HU (1)	HUT68273A (fr)
IL (1)	IL104302A (fr)
MA (1)	MA22761A1 (fr)
MX (1)	MX9300025A (fr)
NO (1)	NO942535L (fr)
NZ (1)	NZ246788A (fr)
OA (1)	OA09961A (fr)
RU (1)	RU94038223A (fr)
SI (1)	SI9300006A (fr)
SK (1)	SK80094A3 (fr)
TW (1)	TW300226B (fr)
WO (1)	WO1993014106A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5641765A (en) *	1992-11-18	1997-06-24	Smithkline Beecham Corporation	17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) *	1992-11-18	1997-11-04	Smithkline Beecham Corporation	17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
MXPA06014230A (es)	2004-06-08	2007-02-14	Univ Temple	Heteroarilsulfonas y sulfonamidas y usos terapeuticos de las mismas.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017568A (en) *	1987-04-29	1991-05-21	Smithkline Beecham Corporation	Steriod 5-alpha-reductase inhibitors

1993
- 1993-01-04 IL IL104302A patent/IL104302A/en not_active IP Right Cessation
- 1993-01-05 MA MA23050A patent/MA22761A1/fr unknown
- 1993-01-05 AP APAP/P/1993/000473A patent/AP370A/en active
- 1993-01-06 SI SI19939300006A patent/SI9300006A/sl unknown
- 1993-01-06 EP EP93902957A patent/EP0643723A4/fr not_active Ceased
- 1993-01-06 HU HU9402030A patent/HUT68273A/hu unknown
- 1993-01-06 MX MX9300025A patent/MX9300025A/es unknown
- 1993-01-06 SK SK800-94A patent/SK80094A3/sk unknown
- 1993-01-06 CN CN93101175A patent/CN1077201A/zh active Pending
- 1993-01-06 WO PCT/US1993/000079 patent/WO1993014106A1/fr not_active Ceased
- 1993-01-06 FI FI943214A patent/FI943214A0/fi unknown
- 1993-01-06 NZ NZ246788A patent/NZ246788A/en unknown
- 1993-01-06 JP JP5512542A patent/JPH07505138A/ja active Pending
- 1993-01-06 CA CA002127272A patent/CA2127272A1/fr not_active Abandoned
- 1993-01-06 CZ CZ941619A patent/CZ161994A3/cs unknown
- 1993-01-06 BR BR9305786A patent/BR9305786A/pt not_active Application Discontinuation
- 1993-01-06 AU AU34348/93A patent/AU666167B2/en not_active Ceased
- 1993-01-06 KR KR1019940702343A patent/KR940703849A/ko not_active Withdrawn
- 1993-01-06 RU RU94038223/04A patent/RU94038223A/ru unknown
- 1993-01-29 TW TW082100552A patent/TW300226B/zh active
1994
- 1994-07-04 OA OA60533A patent/OA09961A/en unknown
- 1994-07-05 NO NO942535A patent/NO942535L/no unknown
- 1994-07-05 BG BG98887A patent/BG98887A/bg unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017568A (en) *	1987-04-29	1991-05-21	Smithkline Beecham Corporation	Steriod 5-alpha-reductase inhibitors

Also Published As

Publication number	Publication date
NZ246788A (en)	1996-11-26
NO942535D0 (no)	1994-07-05
OA09961A (en)	1995-12-11
SI9300006A (en)	1993-09-30
CA2127272A1 (fr)	1993-07-22
FI943214A7 (fi)	1994-07-05
WO1993014106A1 (fr)	1993-07-22
FI943214L (fi)	1994-07-05
MA22761A1 (fr)	1993-10-01
JPH07505138A (ja)	1995-06-08
KR940703849A (ko)	1994-12-12
AP9300473A0 (en)	1993-01-31
RU94038223A (ru)	1997-04-20
AU666167B2 (en)	1996-02-01
CZ161994A3 (en)	1995-03-15
MX9300025A (es)	1994-01-31
AU3434893A (en)	1993-08-03
IL104302A (en)	1998-02-22
BG98887A (bg)	1995-05-31
EP0643723A1 (fr)	1995-03-22
HUT68273A (en)	1995-06-28
HU9402030D0 (en)	1994-09-28
EP0643723A4 (fr)	1995-05-10
IL104302A0 (en)	1993-05-13
FI943214A0 (fi)	1994-07-05
CN1077201A (zh)	1993-10-13
NO942535L (no)	1994-07-05
SK80094A3 (en)	1994-12-07
TW300226B (fr)	1997-03-11
BR9305786A (pt)	1997-02-18

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