AP371A - Amine salts of leukotrine antagonist and its use for crystallizing selectively optical isomers thereof. - Google Patents

Amine salts of leukotrine antagonist and its use for crystallizing selectively optical isomers thereof. Download PDF

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Publication number
AP371A
AP371A APAP/P/1992/000462A AP9200462A AP371A AP 371 A AP371 A AP 371A AP 9200462 A AP9200462 A AP 9200462A AP 371 A AP371 A AP 371A
Authority
AP
ARIPO
Prior art keywords
alkyl
salt
alkoxy
formula
acid
Prior art date
Application number
APAP/P/1992/000462A
Other languages
English (en)
Other versions
AP9200462A0 (en
Inventor
Robert John Mills
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AP9200462A0 publication Critical patent/AP9200462A0/xx
Application granted granted Critical
Publication of AP371A publication Critical patent/AP371A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
APAP/P/1992/000462A 1991-12-12 1992-12-11 Amine salts of leukotrine antagonist and its use for crystallizing selectively optical isomers thereof. AP371A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/806,031 US5214201A (en) 1991-12-12 1991-12-12 Crystallization of optical isomers of leukotriene antagonists

Publications (2)

Publication Number Publication Date
AP9200462A0 AP9200462A0 (en) 1993-01-31
AP371A true AP371A (en) 1994-11-10

Family

ID=25193150

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1992/000462A AP371A (en) 1991-12-12 1992-12-11 Amine salts of leukotrine antagonist and its use for crystallizing selectively optical isomers thereof.

Country Status (21)

Country Link
US (1) US5214201A (fr)
EP (1) EP0638055A1 (fr)
JP (1) JPH07501823A (fr)
CN (1) CN1074212A (fr)
AP (1) AP371A (fr)
AU (1) AU3243993A (fr)
BG (1) BG98842A (fr)
BR (1) BR9207022A (fr)
CA (1) CA2125495A1 (fr)
CZ (1) CZ141294A3 (fr)
FI (1) FI942746A0 (fr)
HU (1) HUT70850A (fr)
IL (1) IL104077A0 (fr)
MA (1) MA22742A1 (fr)
MX (1) MX9207252A (fr)
NO (1) NO942187D0 (fr)
OA (1) OA10025A (fr)
SI (1) SI9200386A (fr)
SK (1) SK69094A3 (fr)
WO (1) WO1993012054A1 (fr)
ZA (1) ZA929677B (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845272A (en) * 1987-07-10 1989-07-04 Kuraray Co., Ltd. Process for the optical resolution of (±)-cis or (±)-trans-permethric acid
US4904822A (en) * 1988-02-19 1990-02-27 Kuraray Co., Ltd. Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid
US4939295A (en) * 1988-07-26 1990-07-03 Zambon Group S.P.A. Process for the preparation of intermediates for the synthesis of diltiazem

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
CA2018437A1 (fr) * 1989-06-14 1990-12-14 James Simpson Frazee Antagonistes des leukotrienes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845272A (en) * 1987-07-10 1989-07-04 Kuraray Co., Ltd. Process for the optical resolution of (±)-cis or (±)-trans-permethric acid
US4904822A (en) * 1988-02-19 1990-02-27 Kuraray Co., Ltd. Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid
US4939295A (en) * 1988-07-26 1990-07-03 Zambon Group S.P.A. Process for the preparation of intermediates for the synthesis of diltiazem

Also Published As

Publication number Publication date
JPH07501823A (ja) 1995-02-23
CA2125495A1 (fr) 1993-06-24
NO942187L (fr) 1994-06-10
HUT70850A (en) 1995-11-28
FI942746L (fi) 1994-06-10
WO1993012054A1 (fr) 1993-06-24
MA22742A1 (fr) 1993-07-01
AP9200462A0 (en) 1993-01-31
CN1074212A (zh) 1993-07-14
HU9401744D0 (en) 1994-09-28
US5214201A (en) 1993-05-25
BR9207022A (pt) 1995-12-12
BG98842A (bg) 1995-05-31
CZ141294A3 (en) 1995-01-18
IL104077A0 (en) 1993-05-13
EP0638055A4 (fr) 1994-10-19
SI9200386A (en) 1993-06-30
FI942746A7 (fi) 1994-06-10
FI942746A0 (fi) 1994-06-10
MX9207252A (es) 1993-07-01
OA10025A (en) 1996-10-14
EP0638055A1 (fr) 1995-02-15
ZA929677B (en) 1993-10-13
SK69094A3 (en) 1995-03-08
NO942187D0 (no) 1994-06-10
AU3243993A (en) 1993-07-19

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