AP827A - Pharmaceutical preparation with trypanocidal qualities for veterinary use. - Google Patents
Pharmaceutical preparation with trypanocidal qualities for veterinary use. Download PDFInfo
- Publication number
- AP827A AP827A APAP/P/1998/001196A AP9801196A AP827A AP 827 A AP827 A AP 827A AP 9801196 A AP9801196 A AP 9801196A AP 827 A AP827 A AP 827A
- Authority
- AP
- ARIPO
- Prior art keywords
- volume
- pharmaceutical preparation
- preparation according
- water
- trypanocidal
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 18
- 230000000654 trypanocidal effect Effects 0.000 title claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 26
- XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960004448 pentamidine Drugs 0.000 claims abstract description 10
- VEQOALNAAJBPNY-UHFFFAOYSA-N antipyrine Chemical compound CN1C(C)=CC(=O)N1C1=CC=CC=C1 VEQOALNAAJBPNY-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims abstract description 9
- 229960005222 phenazone Drugs 0.000 claims abstract description 8
- 239000007864 aqueous solution Substances 0.000 claims abstract description 7
- 229920003086 cellulose ether Polymers 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 229950010741 aceturate Drugs 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 7
- 206010037660 Pyrexia Diseases 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 229920000609 methyl cellulose Polymers 0.000 claims description 4
- 239000001923 methylcellulose Substances 0.000 claims description 4
- 235000010981 methylcellulose Nutrition 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 claims description 3
- 229960004919 procaine Drugs 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 230000003444 anaesthetic effect Effects 0.000 claims 3
- 230000003119 painkilling effect Effects 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 1
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 229960005150 glycerol Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000013543 active substance Substances 0.000 description 5
- 239000003995 emulsifying agent Substances 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 3
- 201000008680 babesiosis Diseases 0.000 description 3
- 239000003139 biocide Substances 0.000 description 3
- 229940102223 injectable solution Drugs 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 239000002690 trypanocidal agent Substances 0.000 description 3
- 208000035473 Communicable disease Diseases 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 2
- 229910052785 arsenic Inorganic materials 0.000 description 2
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000000973 chemotherapeutic effect Effects 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229960004194 lidocaine Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 208000000230 African Trypanosomiasis Diseases 0.000 description 1
- 241000223836 Babesia Species 0.000 description 1
- 241000223840 Babesia bigemina Species 0.000 description 1
- 241000223846 Babesia canis Species 0.000 description 1
- 241000675161 Babesia motasi Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010007269 Carcinogenicity Diseases 0.000 description 1
- 241000324343 Causa Species 0.000 description 1
- 208000035415 Reinfection Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007670 carcinogenicity Effects 0.000 description 1
- 231100000260 carcinogenicity Toxicity 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- XNYZHCFCZNMTFY-UHFFFAOYSA-N diminazene Chemical compound C1=CC(C(=N)N)=CC=C1N\N=N\C1=CC=C(C(N)=N)C=C1 XNYZHCFCZNMTFY-UHFFFAOYSA-N 0.000 description 1
- 229950007095 diminazene Drugs 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000029080 human African trypanosomiasis Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 208000028172 protozoa infectious disease Diseases 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 201000002612 sleeping sickness Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 201000002311 trypanosomiasis Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1995130708 DE19530708C2 (de) | 1995-08-21 | 1995-08-21 | Pharmazeutisches Präparat mit trypanoziden Eigenschaften |
| PCT/EP1996/003657 WO1997006769A2 (de) | 1995-08-21 | 1996-08-20 | Pharmazeutisches präparat mit trypanoziden eigenschaften enthaltend diminazen, pentamidin und phenazon |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9801196A0 AP9801196A0 (en) | 1998-03-31 |
| AP827A true AP827A (en) | 2000-04-28 |
Family
ID=7769997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1998/001196A AP827A (en) | 1995-08-21 | 1996-08-20 | Pharmaceutical preparation with trypanocidal qualities for veterinary use. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0845983A2 (de) |
| AP (1) | AP827A (de) |
| AU (1) | AU6875096A (de) |
| DE (1) | DE19530708C2 (de) |
| EA (1) | EA199800218A1 (de) |
| OA (1) | OA10665A (de) |
| WO (1) | WO1997006769A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE29618094U1 (de) * | 1996-10-18 | 1998-02-12 | Bourdichon, Alain Jaques, 22301 Hamburg | Pharmazeutisches Präparat |
| DE19853937A1 (de) * | 1998-11-24 | 2000-05-25 | Chambord Ltd | Pharmazeutisches Präparat |
| DE10325672A1 (de) * | 2003-06-03 | 2004-12-23 | Tropmed Gmbh | Pharmazeutisches Präparat zur Behandlung von parasitären Tropenkrankheiten |
| CN105168121A (zh) * | 2015-08-28 | 2015-12-23 | 重庆布尔动物药业有限公司 | 兽用复方三氮脒注射液及其制备方法 |
| RU2638433C1 (ru) * | 2016-12-15 | 2017-12-13 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Горский государственный аграрный университет" | Способ повышения лечебной эффективности Диминазина-70 при пироплазмозе крупного рогатого скота |
| RU2638444C1 (ru) * | 2016-12-15 | 2017-12-13 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Горский государственный аграрный университет" | Способ повышения лечебной эффективности пироплазмоза крупного рогатого скота Неозидином-М в сочетании с лазеропунктурой |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4309415A1 (de) * | 1993-03-19 | 1994-09-22 | Alan Jacques Bourdichon | Pharmazeutisches Präparat |
-
1995
- 1995-08-21 DE DE1995130708 patent/DE19530708C2/de not_active Expired - Fee Related
-
1996
- 1996-08-20 EA EA199800218A patent/EA199800218A1/ru unknown
- 1996-08-20 EP EP96929285A patent/EP0845983A2/de not_active Ceased
- 1996-08-20 WO PCT/EP1996/003657 patent/WO1997006769A2/de not_active Ceased
- 1996-08-20 AP APAP/P/1998/001196A patent/AP827A/en active
- 1996-08-20 AU AU68750/96A patent/AU6875096A/en not_active Abandoned
-
1998
- 1998-02-20 OA OA9800022A patent/OA10665A/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4309415A1 (de) * | 1993-03-19 | 1994-09-22 | Alan Jacques Bourdichon | Pharmazeutisches Präparat |
Also Published As
| Publication number | Publication date |
|---|---|
| DE19530708C2 (de) | 1999-01-07 |
| WO1997006769A2 (de) | 1997-02-27 |
| EA199800218A1 (ru) | 1998-12-24 |
| DE19530708A1 (de) | 1997-02-27 |
| EP0845983A2 (de) | 1998-06-10 |
| AU6875096A (en) | 1997-03-12 |
| AP9801196A0 (en) | 1998-03-31 |
| OA10665A (en) | 2002-09-25 |
| WO1997006769A3 (de) | 1997-05-09 |
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