OA10665A - Pharmaceutical preparation with trypanocidal properties containing diminazene pentamidine and phenazone - Google Patents

Pharmaceutical preparation with trypanocidal properties containing diminazene pentamidine and phenazone Download PDF

Info

Publication number: OA10665A
Authority: OA; OAPI
Prior art keywords: volume; water; préparation; pharmaceutical; pharmaceutical préparation
Prior art date: 1995-08-21

Application number

OA9800022A

Other languages

English (en)

Inventor

Alain Jacques Bourdichon

Original Assignee

Alain Jacques Bourdichon

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-21

Filing date

1998-02-20

Publication date

2002-09-25

1998-02-20 Application filed by Alain Jacques Bourdichon filed Critical Alain Jacques Bourdichon

2002-09-25 Publication of OA10665A publication Critical patent/OA10665A/en

Links

VEQOALNAAJBPNY-UHFFFAOYSA-N antipyrine Chemical compound CN1C(C)=CC(=O)N1C1=CC=CC=C1 VEQOALNAAJBPNY-UHFFFAOYSA-N 0.000 title claims abstract description 10
XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 title claims abstract description 10
229960004448 pentamidine Drugs 0.000 title claims abstract description 10
229960005222 phenazone Drugs 0.000 title claims abstract description 9
230000000654 trypanocidal effect Effects 0.000 title claims abstract description 7
XNYZHCFCZNMTFY-UHFFFAOYSA-N diminazene Chemical compound C1=CC(C(=N)N)=CC=C1N\N=N\C1=CC=C(C(N)=N)C=C1 XNYZHCFCZNMTFY-UHFFFAOYSA-N 0.000 title description 2
229950007095 diminazene Drugs 0.000 title description 2
239000000825 pharmaceutical preparation Substances 0.000 title 1
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 21
239000007864 aqueous solution Substances 0.000 claims abstract description 7
239000003814 drug Substances 0.000 claims abstract description 7
229920003086 cellulose ether Polymers 0.000 claims abstract description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
229950010741 aceturate Drugs 0.000 claims description 11
206010037660 Pyrexia Diseases 0.000 claims description 6
229940079593 drug Drugs 0.000 claims description 5
229920000609 methyl cellulose Polymers 0.000 claims description 3
239000001923 methylcellulose Substances 0.000 claims description 3
235000010981 methylcellulose Nutrition 0.000 claims description 3
229960004919 procaine Drugs 0.000 claims description 3
MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 claims description 3
239000002904 solvent Substances 0.000 claims description 3
BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims description 2
229960001138 acetylsalicylic acid Drugs 0.000 claims description 2
230000003444 anaesthetic effect Effects 0.000 claims 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
230000003119 painkilling effect Effects 0.000 claims 2
239000001913 cellulose Substances 0.000 claims 1
229920002678 cellulose Polymers 0.000 claims 1
230000007935 neutral effect Effects 0.000 claims 1
229920000642 polymer Polymers 0.000 claims 1
239000011780 sodium chloride Substances 0.000 claims 1
235000011187 glycerol Nutrition 0.000 abstract description 7
229960005150 glycerol Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000243 solution Substances 0.000 description 7
239000000203 mixture Substances 0.000 description 6
239000013543 active substance Substances 0.000 description 5
208000015181 infectious disease Diseases 0.000 description 5
238000002347 injection Methods 0.000 description 5
239000007924 injection Substances 0.000 description 5
239000003795 chemical substances by application Substances 0.000 description 4
239000003995 emulsifying agent Substances 0.000 description 4
NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 3
208000002193 Pain Diseases 0.000 description 3
201000008680 babesiosis Diseases 0.000 description 3
229960004194 lidocaine Drugs 0.000 description 3
238000011282 treatment Methods 0.000 description 3
208000035473 Communicable disease Diseases 0.000 description 2
229910052785 arsenic Inorganic materials 0.000 description 2
RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 2
239000003139 biocide Substances 0.000 description 2
230000000973 chemotherapeutic effect Effects 0.000 description 2
238000002512 chemotherapy Methods 0.000 description 2
201000010099 disease Diseases 0.000 description 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
229940102223 injectable solution Drugs 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
230000036407 pain Effects 0.000 description 2
208000000230 African Trypanosomiasis Diseases 0.000 description 1
241000223836 Babesia Species 0.000 description 1
241000223840 Babesia bigemina Species 0.000 description 1
241000223846 Babesia canis Species 0.000 description 1
241000675161 Babesia motasi Species 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
206010007269 Carcinogenicity Diseases 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
208000035415 Reinfection Diseases 0.000 description 1
241000489254 Tetranychus takafujii Species 0.000 description 1
241000223778 Theileria annulata Species 0.000 description 1
241000700605 Viruses Species 0.000 description 1
230000006978 adaptation Effects 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
230000007670 carcinogenicity Effects 0.000 description 1
231100000260 carcinogenicity Toxicity 0.000 description 1
210000003169 central nervous system Anatomy 0.000 description 1
229940116592 central nervous system diagnostic radiopharmaceuticals Drugs 0.000 description 1
239000003638 chemical reducing agent Substances 0.000 description 1
238000011109 contamination Methods 0.000 description 1
239000013078 crystal Substances 0.000 description 1
239000000975 dye Substances 0.000 description 1
150000002170 ethers Chemical class 0.000 description 1
208000021760 high fever Diseases 0.000 description 1
208000029080 human African trypanosomiasis Diseases 0.000 description 1
229940071826 hydroxyethyl cellulose Drugs 0.000 description 1
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
239000001863 hydroxypropyl cellulose Substances 0.000 description 1
235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
229940071676 hydroxypropylcellulose Drugs 0.000 description 1
244000045947 parasite Species 0.000 description 1
-1 pentamethylenedioxy Chemical group 0.000 description 1
239000000843 powder Substances 0.000 description 1
208000028172 protozoa infectious disease Diseases 0.000 description 1
230000035939 shock Effects 0.000 description 1
201000002612 sleeping sickness Diseases 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
229940126585 therapeutic drug Drugs 0.000 description 1
239000002690 trypanocidal agent Substances 0.000 description 1
201000002311 trypanosomiasis Diseases 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

OA9800022A 1995-08-21 1998-02-20 Pharmaceutical preparation with trypanocidal properties containing diminazene pentamidine and phenazone OA10665A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1995130708 DE19530708C2 (de)	1995-08-21	1995-08-21	Pharmazeutisches Präparat mit trypanoziden Eigenschaften

Publications (1)

Publication Number	Publication Date
OA10665A true OA10665A (en)	2002-09-25

Family

ID=7769997

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA9800022A OA10665A (en)	1995-08-21	1998-02-20	Pharmaceutical preparation with trypanocidal properties containing diminazene pentamidine and phenazone

Country Status (7)

Country	Link
EP (1)	EP0845983A2 (de)
AP (1)	AP827A (de)
AU (1)	AU6875096A (de)
DE (1)	DE19530708C2 (de)
EA (1)	EA199800218A1 (de)
OA (1)	OA10665A (de)
WO (1)	WO1997006769A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE29618094U1 (de) *	1996-10-18	1998-02-12	Bourdichon, Alain Jaques, 22301 Hamburg	Pharmazeutisches Präparat
DE19853937A1 (de) *	1998-11-24	2000-05-25	Chambord Ltd	Pharmazeutisches Präparat
DE10325672A1 (de) *	2003-06-03	2004-12-23	Tropmed Gmbh	Pharmazeutisches Präparat zur Behandlung von parasitären Tropenkrankheiten
CN105168121A (zh) *	2015-08-28	2015-12-23	重庆布尔动物药业有限公司	兽用复方三氮脒注射液及其制备方法
RU2638433C1 (ru) *	2016-12-15	2017-12-13	Федеральное государственное бюджетное образовательное учреждение высшего образования "Горский государственный аграрный университет"	Способ повышения лечебной эффективности Диминазина-70 при пироплазмозе крупного рогатого скота
RU2638444C1 (ru) *	2016-12-15	2017-12-13	Федеральное государственное бюджетное образовательное учреждение высшего образования "Горский государственный аграрный университет"	Способ повышения лечебной эффективности пироплазмоза крупного рогатого скота Неозидином-М в сочетании с лазеропунктурой

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4309415C2 (de) *	1993-03-19	1996-11-07	Alain Jaques Bourdichon	Pharmazeutisches Präparat

1995
- 1995-08-21 DE DE1995130708 patent/DE19530708C2/de not_active Expired - Fee Related
1996
- 1996-08-20 EA EA199800218A patent/EA199800218A1/ru unknown
- 1996-08-20 EP EP96929285A patent/EP0845983A2/de not_active Ceased
- 1996-08-20 WO PCT/EP1996/003657 patent/WO1997006769A2/de not_active Ceased
- 1996-08-20 AP APAP/P/1998/001196A patent/AP827A/en active
- 1996-08-20 AU AU68750/96A patent/AU6875096A/en not_active Abandoned
1998
- 1998-02-20 OA OA9800022A patent/OA10665A/en unknown

Also Published As

Publication number	Publication date
DE19530708C2 (de)	1999-01-07
WO1997006769A2 (de)	1997-02-27
EA199800218A1 (ru)	1998-12-24
DE19530708A1 (de)	1997-02-27
EP0845983A2 (de)	1998-06-10
AU6875096A (en)	1997-03-12
AP9801196A0 (en)	1998-03-31
AP827A (en)	2000-04-28
WO1997006769A3 (de)	1997-05-09

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