AR018596A1 - Compuestos azapoliciclicos fusionados con arilo utiles en el tratamiento de desordenes neurologicos y fisiologicos, composiciones farmaceuticas,metodos de tratamiento que los utilizan - Google Patents
Compuestos azapoliciclicos fusionados con arilo utiles en el tratamiento de desordenes neurologicos y fisiologicos, composiciones farmaceuticas,metodos de tratamiento que los utilizanInfo
- Publication number
- AR018596A1 AR018596A1 ARP990101941A ARP990101941A AR018596A1 AR 018596 A1 AR018596 A1 AR 018596A1 AR P990101941 A ARP990101941 A AR P990101941A AR P990101941 A ARP990101941 A AR P990101941A AR 018596 A1 AR018596 A1 AR 018596A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- amino
- alkoxy
- aryl
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Un compuesto azapolicíclico fusionado con arilo de la formula (I), en la que Z es CH2, C(=O) o CF2; R1 es hidrogeno, alquilo C1-6, alquenilo C3-6 noconjugado, bencilo, XC(=O)R13 o -CH2CH2-O-alquilo C1-4; R2 y R3 se seleccionan independientemente entre hidrogeno, alquenilo C2-6, alquinilo C2-6, hidroxi,nitro, amino, halo, ciano, -SOq-alquilo C1-6 donde q es 0, 1 o 2, alquilamino C1-6, [alquil C1-6]2 amino, CO2R4, CONR5R6, SO2NR7R8, C(=O)R13, XC(=O)R13,aril-alquilo C0-3 o aril-alquilo C0-3-O dondedicho arilo se selecciona entre fenilo y naftilo, heteroaril-alquilo C0-3 o heteroaril-alquilo C0-3-O, dondedicho heteroarilo se selecciona entre anillos aromáticos de 5-7 miembros que contienen de 1-4 heteroátomos seleccionados entre oxígeno, nitrogeno y azufrey X2-alcoxi C0-6-alquilo C0-6, donde X2 está ausente o X2 es alquilamino C1-6 o [alquil C1-6]2 amino y donde el radical alcoxi C0-6 -alquilo C0-6 de dichoX2-alcoxi C0-6-alquilo C0-6 contiene al menos un átomo de carbono, y donde de 1-3 de los átomos de carbono de dicho radical alcoxi C0-6-alquilo C0-6 puedenreemplazarse opcionalmente por un átomo de oxígeno, nitrogeno o azufre, con la condicion de que dos cualesquiera de tales heteroátomos tienen queestar separados por al menos dosátomos de carbono, y donde cualquiera de los radicales alquilo de dicho alcoxi C0-6-alquilo C0-6 puede estaropcionalmente sustituido con 2 -7 átomos de fluor, y donde uno de los átomos de carbono de cada uno de los radicales alquilo de dicho aril-alquiloC0-3 y dicho heteroaril-alquilo C0-3 puede reemplazarse opcionalmente por un átomo de oxígeno, nitrogeno o azufre, y donde cada uno de los grupos arilo yheteroarilo anteriores puede estar opcionalmente sustituido con uno o más sustituyentes, preferiblemente de 0 a 2 sustituyentes, seleccionadosindependientemente entre alquilo C1-6 opcionalmente sustituido con 1-7 átomos de fluor, alcoxi C1-6 opcionalmente sustituido con 2 a 7 átomos de fluor,halo (por ejemplo, cloro, fluor, bromo o yodo), hidroxi, nitro, ciano, amino, alquilamino C1-6 y [alquil C1-6]2 amino; o R2 y R3, junto con los
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8355698P | 1998-04-29 | 1998-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018596A1 true AR018596A1 (es) | 2001-11-28 |
Family
ID=22179102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990101941A AR018596A1 (es) | 1998-04-29 | 1999-04-27 | Compuestos azapoliciclicos fusionados con arilo utiles en el tratamiento de desordenes neurologicos y fisiologicos, composiciones farmaceuticas,metodos de tratamiento que los utilizan |
Country Status (41)
| Country | Link |
|---|---|
| US (3) | US6462035B1 (es) |
| EP (1) | EP1076650B1 (es) |
| JP (1) | JP2002513007A (es) |
| KR (1) | KR100420423B1 (es) |
| CN (1) | CN1144787C (es) |
| AP (1) | AP1154A (es) |
| AR (1) | AR018596A1 (es) |
| AT (1) | ATE258921T1 (es) |
| AU (1) | AU749831B2 (es) |
| BG (1) | BG64556B1 (es) |
| BR (1) | BR9910058A (es) |
| CA (1) | CA2330576A1 (es) |
| CO (1) | CO5021124A1 (es) |
| DE (1) | DE69914594T2 (es) |
| DK (1) | DK1076650T3 (es) |
| DZ (1) | DZ2778A1 (es) |
| EA (1) | EA003669B1 (es) |
| ES (1) | ES2213354T3 (es) |
| GT (1) | GT199900059A (es) |
| HR (1) | HRP20000731A2 (es) |
| HU (1) | HUP0103340A3 (es) |
| ID (1) | ID26700A (es) |
| IL (1) | IL138917A0 (es) |
| IS (1) | IS5649A (es) |
| MA (1) | MA26623A1 (es) |
| MY (1) | MY133474A (es) |
| NO (1) | NO317300B1 (es) |
| NZ (1) | NZ507035A (es) |
| OA (1) | OA11506A (es) |
| PA (1) | PA8471301A1 (es) |
| PE (1) | PE20000435A1 (es) |
| PL (1) | PL344010A1 (es) |
| PT (1) | PT1076650E (es) |
| SK (1) | SK15952000A3 (es) |
| TN (1) | TNSN99080A1 (es) |
| TR (1) | TR200003122T2 (es) |
| UA (1) | UA61991C2 (es) |
| UY (1) | UY25636A1 (es) |
| WO (1) | WO1999055680A1 (es) |
| YU (1) | YU64400A (es) |
| ZA (1) | ZA992971B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605610B1 (en) * | 1997-12-31 | 2003-08-12 | Pfizer Inc | Aryl fused azapolycyclic compounds |
| PT1044189E (pt) | 1997-12-31 | 2008-04-22 | Pfizer Prod Inc | Compostos azapolicíclicos condensados com arilo |
| US20010036943A1 (en) * | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
| PT1383733E (pt) | 2001-04-20 | 2008-04-15 | Pfizer Prod Inc | Processo para a preparação de indenos 1,3-substituídos e compostos azapolicíclicos fundidos com arilo |
| PL370549A1 (en) * | 2001-10-31 | 2005-05-30 | Pfizer Products Inc. | Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome |
| DE60228478D1 (de) | 2001-11-30 | 2008-10-02 | Pfizer Prod Inc | Aryl-annellierte azapolyzyklische verbindungen |
| US20060089400A1 (en) * | 2002-05-03 | 2006-04-27 | The Vernalis Group Of Companies | Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases |
| US20040224963A1 (en) * | 2003-05-09 | 2004-11-11 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal |
| US20040224962A1 (en) * | 2003-05-09 | 2004-11-11 | Pfizer Inc | Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss |
| ES2331245T3 (es) * | 2003-07-21 | 2009-12-28 | Pfizer Products Inc. | Compuestos azapoliciclicos condensados con heteroarilo que reducen la adiccion a la nicotina. |
| MXPA06000892A (es) * | 2003-07-21 | 2006-03-30 | Pfizer Prod Inc | Compuestos azapoliciclicos arilo fusionados. |
| US20050043407A1 (en) * | 2003-08-22 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| CA2591330A1 (en) * | 2004-12-07 | 2006-06-15 | Pfizer Products Inc. | 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a] inden-7-one derivatives which bind to neuronal nicotinic acetylcholine specific receptor sites and are useful in modulatingcholinergic function and in the treatment of addictive disorders |
| US20060210497A1 (en) * | 2005-03-18 | 2006-09-21 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Novel resorcinol derivatives |
| US20060210498A1 (en) | 2005-03-18 | 2006-09-21 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Novel resorcinol derivatives for skin |
| DE102005061426A1 (de) * | 2005-12-22 | 2007-07-05 | Grünenthal GmbH | Substituierte tricyclische Piperidon-Derivate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3687937A (en) * | 1970-06-23 | 1972-08-29 | Us Of America The | 1,5-methano-3-benzazocine derivatives |
| JPS4914473A (es) * | 1972-06-09 | 1974-02-07 | ||
| JPS4924968A (es) * | 1972-07-01 | 1974-03-05 |
-
1999
- 1999-04-08 WO PCT/IB1999/000617 patent/WO1999055680A1/en not_active Ceased
- 1999-04-08 DK DK99910600T patent/DK1076650T3/da active
- 1999-04-08 PL PL99344010A patent/PL344010A1/xx unknown
- 1999-04-08 CA CA002330576A patent/CA2330576A1/en not_active Abandoned
- 1999-04-08 US US09/582,513 patent/US6462035B1/en not_active Expired - Fee Related
- 1999-04-08 AT AT99910600T patent/ATE258921T1/de not_active IP Right Cessation
- 1999-04-08 YU YU64400A patent/YU64400A/sh unknown
- 1999-04-08 DE DE69914594T patent/DE69914594T2/de not_active Expired - Fee Related
- 1999-04-08 HR HR20000731A patent/HRP20000731A2/hr not_active Application Discontinuation
- 1999-04-08 HU HU0103340A patent/HUP0103340A3/hu unknown
- 1999-04-08 PT PT99910600T patent/PT1076650E/pt unknown
- 1999-04-08 TR TR2000/03122T patent/TR200003122T2/xx unknown
- 1999-04-08 JP JP2000545840A patent/JP2002513007A/ja not_active Withdrawn
- 1999-04-08 NZ NZ507035A patent/NZ507035A/en unknown
- 1999-04-08 EP EP99910600A patent/EP1076650B1/en not_active Expired - Lifetime
- 1999-04-08 KR KR10-2000-7012039A patent/KR100420423B1/ko not_active Expired - Fee Related
- 1999-04-08 BR BR9910058-4A patent/BR9910058A/pt not_active Application Discontinuation
- 1999-04-08 ES ES99910600T patent/ES2213354T3/es not_active Expired - Lifetime
- 1999-04-08 ID IDW20002185A patent/ID26700A/id unknown
- 1999-04-08 EA EA200000996A patent/EA003669B1/ru not_active IP Right Cessation
- 1999-04-08 SK SK1595-2000A patent/SK15952000A3/sk unknown
- 1999-04-08 IL IL13891799A patent/IL138917A0/xx unknown
- 1999-04-08 AU AU29516/99A patent/AU749831B2/en not_active Ceased
- 1999-04-08 CN CNB998054542A patent/CN1144787C/zh not_active Expired - Fee Related
- 1999-04-20 GT GT199900059A patent/GT199900059A/es unknown
- 1999-04-23 PE PE1999000340A patent/PE20000435A1/es not_active Application Discontinuation
- 1999-04-27 MY MYPI99001648A patent/MY133474A/en unknown
- 1999-04-27 AR ARP990101941A patent/AR018596A1/es unknown
- 1999-04-28 MA MA25556A patent/MA26623A1/fr unknown
- 1999-04-28 TN TNTNSN99080A patent/TNSN99080A1/fr unknown
- 1999-04-28 DZ DZ990078A patent/DZ2778A1/xx active
- 1999-04-28 ZA ZA9902971A patent/ZA992971B/xx unknown
- 1999-04-29 PA PA19998471301A patent/PA8471301A1/es unknown
- 1999-04-29 AP APAP/P/1999/001524A patent/AP1154A/en active
- 1999-04-29 CO CO99026005A patent/CO5021124A1/es unknown
- 1999-08-03 UY UY25636A patent/UY25636A1/es not_active Application Discontinuation
- 1999-08-04 UA UA2000095418A patent/UA61991C2/uk unknown
-
2000
- 2000-09-29 IS IS5649A patent/IS5649A/is unknown
- 2000-10-25 OA OA1200000295A patent/OA11506A/en unknown
- 2000-10-26 NO NO20005397A patent/NO317300B1/no unknown
- 2000-11-24 BG BG104983A patent/BG64556B1/bg unknown
-
2002
- 2002-08-13 US US10/217,771 patent/US6706702B2/en not_active Expired - Fee Related
-
2004
- 2004-01-23 US US10/764,167 patent/US7122534B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR017967A1 (es) | Compuestos azapoliciclicos condensados con arilo, composiciones farmaceuticas de los mismos, su uso en la preparacion de medicamentos. | |
| AR017236A1 (es) | Compuestos biciclo [2.2.1] heptanos, composiciones farmaceuticas, procedimientos para tratar | |
| FI904327A0 (fi) | N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. | |
| EA200300777A1 (ru) | N-фенпропилциклопентил-замещенные производные глутарамида в качестве nep ингибиторов для fsad | |
| EA200100755A1 (ru) | 4-оксо-1,4-дигидро-3-хинолинкарбоксамиды как антивирусные агенты | |
| EP1052254A4 (en) | NITROGENIC HETEROCYCLIC DERIVATIVES AND DRUGS PRODUCED FROM SUCH DERIVATIVES | |
| DK0842661T3 (da) | Anvendelse af estrogenagonister og -antagonister til fremstilling af et lægemiddel til behandling af atherosclerose, uafhængigt af lipidsænkning | |
| PE20030772A1 (es) | Derivados de pirimidina | |
| DK0756595T3 (da) | Substituerede 1,3-oxathiolaner med antivirale egenskaber | |
| DK0790987T3 (da) | Aminotetrazol-derivater, der er anvendelige som nitrogenoxidsynthaseinhibitorer | |
| DK0657422T3 (da) | Naphthyloxyeddikesyrederivater som PEG2-agonister og -antagonister | |
| DK374085A (da) | Tryptamin-derivater, deres fremstilling og anvendelse som laegemidler | |
| AR016644A1 (es) | Compuestos de 2-aminopiridinas con sustituyentes alcoxi ramificados, composicion farmaceutica y uso para la manufactura de medicamentos | |
| ATE243209T1 (de) | Tetrahydro gamma-carboline | |
| PT96030A (pt) | Processo para a preparacao de aminocarbonilcarbamatos relacionados com fisoestigmina e de composicoes farmaceuticas que os contem | |
| NO162421C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylinderivater og syreaddisjonssalter derav. | |
| AR060498A1 (es) | Compuestos de tieno [2,3-b] piridinas | |
| DK12584A (da) | Bicyclo(4.2.0)1,3,5-octatrienderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse | |
| FI914219A0 (fi) | 3-(1h-indazol-3-yl)-4-pyridinaminer, foerfarande och mellanprodukter foer deras framstaellning och deras anvaendning som laekemedel. | |
| ATE56967T1 (de) | Amidderivate. | |
| DE69527854D1 (de) | Derivate substituierter amidinonaphthylester | |
| ES2183500T3 (es) | Nuevos compuestos y composiciones farmaceuticas que los contienen. | |
| FI822706A0 (fi) | Foerfarande foer framstaellning av farmakologiskt aktiva heteroaryloxipropanolaminer | |
| GR82272B (es) | ||
| ES2031921T3 (es) | Derivados 5-aminoetilados de la oxazolidinona-2, su procedimiento de fabricacion y su aplicacion terapeutica. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |