AR020054A1 - COMPOSICIoN QUE COMPRENDE UN ADENOVIRUS - Google Patents

COMPOSICIoN QUE COMPRENDE UN ADENOVIRUS

Info

Publication number
AR020054A1
AR020054A1 ARP990100656A ARP990100656A AR020054A1 AR 020054 A1 AR020054 A1 AR 020054A1 AR P990100656 A ARP990100656 A AR P990100656A AR P990100656 A ARP990100656 A AR P990100656A AR 020054 A1 AR020054 A1 AR 020054A1
Authority
AR
Argentina
Prior art keywords
adenovirus
composition understanding
virus
virus preparations
composition
Prior art date
Application number
ARP990100656A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR020054A1 publication Critical patent/AR020054A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composicion que contiene virus en una formulacion que contiene un polihidroxi hidrocarburo regulada para mantener un ph en el intervalo de aproximadamente7 a aproximadamente 8,5 a una temperatura en el orden de aproximadamente 2sC a 27sC; preparadosde virus concentrado y purificado y métodos para concentrar ypurificar dichos preparados de virus. Estos virus se utilizan para terapia génica.
ARP990100656A 1998-02-17 1999-02-23 COMPOSICIoN QUE COMPRENDE UN ADENOVIRUS AR020054A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2446298A 1998-02-17 1998-02-17
US7964398A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
AR020054A1 true AR020054A1 (es) 2002-04-10

Family

ID=26698472

Family Applications (3)

Application Number Title Priority Date Filing Date
ARP990100656A AR020054A1 (es) 1998-02-17 1999-02-23 COMPOSICIoN QUE COMPRENDE UN ADENOVIRUS
ARP070104577A AR063315A2 (es) 1998-02-17 2007-10-16 Composicion que comprende un virus, y metodos para concentrar y purificar preparados de virus
ARP070104576A AR063314A2 (es) 1998-02-17 2007-10-16 Metodos para purificar preparados de virus

Family Applications After (2)

Application Number Title Priority Date Filing Date
ARP070104577A AR063315A2 (es) 1998-02-17 2007-10-16 Composicion que comprende un virus, y metodos para concentrar y purificar preparados de virus
ARP070104576A AR063314A2 (es) 1998-02-17 2007-10-16 Metodos para purificar preparados de virus

Country Status (24)

Country Link
EP (4) EP1054955B1 (es)
JP (3) JP4358434B2 (es)
KR (5) KR100912362B1 (es)
CN (2) CN100374551C (es)
AR (3) AR020054A1 (es)
AT (3) ATE371020T1 (es)
AU (1) AU757976B2 (es)
BR (1) BR9908015A (es)
CA (2) CA2723040A1 (es)
CO (1) CO4820440A1 (es)
DE (3) DE69942708D1 (es)
DK (1) DK1054955T3 (es)
ES (2) ES2290613T3 (es)
HU (1) HU226015B1 (es)
ID (1) ID28298A (es)
IL (2) IL137510A0 (es)
MY (1) MY141641A (es)
NO (1) NO20004104L (es)
PE (1) PE20000265A1 (es)
PL (1) PL197747B1 (es)
PT (1) PT1054955E (es)
SK (1) SK11842000A3 (es)
TW (1) TWI232107B (es)
WO (1) WO1999041416A2 (es)

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US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
EP2420247A1 (en) 2000-03-07 2012-02-22 Merck Sharp & Dohme Corp. Adenovirus formulations
US7456009B2 (en) 2000-03-07 2008-11-25 Merck & Co., Inc. Adenovirus formulations
US20020064860A1 (en) 2000-11-29 2002-05-30 Schering Corporation Method for purifying adenoviruses
JP2002241311A (ja) * 2000-12-12 2002-08-28 Japan Tobacco Inc 界面活性剤を含む医薬組成物
EP1453536A4 (en) 2001-12-12 2009-08-26 Mayne Pharma Int Pty Ltd COMPOSITION FOR PRESERVING VIRUSES
US20030153065A1 (en) * 2002-01-14 2003-08-14 Genvec, Inc. Composition and method for maintaining non-enveloped viral vectors
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EP1815029A4 (en) 2004-11-03 2009-06-10 Introgen Therapeutics Inc NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF ADENOVIRAL VECTORS
CA2590943C (en) 2004-12-13 2013-10-22 Canji, Inc. Cell lines for production of replication-defective adenovirus
DK1869171T4 (en) 2005-04-11 2016-01-18 Crucell Holland Bv Virus cleaning using ultrafiltration
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DE602006019916D1 (de) 2005-12-12 2011-03-10 Canji Inc Adenovirale expressionsvektoren mit einer expressionskassette im e1-bereich und einer inaktivierten e2b-polymerase
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AU2011336413B2 (en) 2010-12-02 2015-01-22 Oncolytics Biotech Inc. Liquid viral formulations
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US8932607B2 (en) 2012-03-12 2015-01-13 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
JP5770952B2 (ja) 2012-03-12 2015-08-26 クルセル ホランド ベー ヴェー 改変末端を有する組換えアデノウイルスのバッチ
EA026504B1 (ru) 2012-03-22 2017-04-28 Круселл Холланд Б.В. Вакцина против rsv
US9119813B2 (en) 2012-03-22 2015-09-01 Crucell Holland B.V. Vaccine against RSV
JP6469081B2 (ja) 2013-04-25 2019-02-13 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． 安定化された可溶性融合前ｒｓｖｆポリペプチド
MY171210A (en) 2013-06-17 2019-10-02 Janssen Vaccines & Prevention Bv Stabilized soluble pre-fusion rsv f polypeptides
SG11201609908VA (en) * 2014-05-28 2016-12-29 Agency Science Tech & Res Virus reduction method
WO2016166088A1 (en) 2015-04-14 2016-10-20 Janssen Vaccines & Prevention B.V. Recombinant adenovirus expressing two transgenes with a bidirectional promoter
CN107847581B (zh) 2015-07-07 2022-03-22 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f多肽
ES2839880T3 (es) 2015-07-07 2021-07-06 Janssen Vaccines & Prevention Bv Vacuna contra el VRS
PH12022552125A1 (en) 2016-04-05 2023-04-12 Janssen Vaccines & Prevention Bv Stabilized soluble pre-fusion rsv f proteins
KR102500970B1 (ko) 2016-04-05 2023-02-17 얀센 백신스 앤드 프리벤션 비.브이. Rsv에 대한 백신
IL264119B2 (en) 2016-05-30 2023-04-01 Janssen Vaccines Prevention B V f proteins of rsv are stabilized before fusion
KR102307065B1 (ko) 2016-06-20 2021-09-30 얀센 백신스 앤드 프리벤션 비.브이. 강력하고 균형 잡힌 양방향성 프로모터
US10744196B2 (en) 2016-07-14 2020-08-18 Janssen Vaccines & Prevention B.V. HPV vaccines
US11229692B2 (en) 2017-05-17 2022-01-25 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
WO2018210871A1 (en) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
WO2019021305A1 (en) * 2017-07-24 2019-01-31 Ella Foundation VACCINE AGAINST FOOT AND MOUTH DISEASE
WO2019053109A1 (en) 2017-09-15 2019-03-21 Janssen Vaccines & Prevention B.V. METHOD FOR SAFE INDUCTION OF IMMUNITY AGAINST RSV
JP2022513025A (ja) 2018-11-13 2022-02-07 ヤンセン ファッシンズ アンド プリベンション ベーフェー 安定化された融合前ｒｓｖ ｆタンパク質
EP3990031A4 (en) * 2019-06-28 2023-08-09 Takeda Pharmaceutical Company Limited Adeno-associated virus purification methods
TW202204380A (zh) 2020-01-31 2022-02-01 美商詹森藥物公司 用於預防及治療冠狀病毒感染之組合物及方法－sars-cov-2疫苗
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Also Published As

Publication number Publication date
KR20080065614A (ko) 2008-07-14
CO4820440A1 (es) 1999-07-28
KR100912362B1 (ko) 2009-08-19
EP1526174B1 (en) 2007-08-22
KR100862169B1 (ko) 2008-10-09
CN1297478A (zh) 2001-05-30
ES2290613T3 (es) 2008-02-16
IL137510A0 (en) 2001-07-24
EP1526173A2 (en) 2005-04-27
KR101018992B1 (ko) 2011-03-07
DE69942708D1 (de) 2010-10-07
ATE371020T1 (de) 2007-09-15
AU2653899A (en) 1999-08-30
EP1054955B1 (en) 2006-10-04
DK1054955T3 (da) 2007-01-15
NO20004104D0 (no) 2000-08-16
HU226015B1 (en) 2008-02-28
KR100991683B1 (ko) 2010-11-04
KR20080065615A (ko) 2008-07-14
ATE478945T1 (de) 2010-09-15
TWI232107B (en) 2005-05-11
CN100374551C (zh) 2008-03-12
PL342847A1 (en) 2001-07-16
ES2272053T3 (es) 2007-04-16
MY141641A (en) 2010-05-31
WO1999041416A2 (en) 1999-08-19
CN101164623B (zh) 2012-11-14
CA2320419C (en) 2011-02-08
HUP0100670A3 (en) 2003-10-28
PT1054955E (pt) 2007-01-31
KR20090127947A (ko) 2009-12-14
NO20004104L (no) 2000-10-17
IL137510A (en) 2012-10-31
JP2010213727A (ja) 2010-09-30
ID28298A (id) 2001-05-10
ATE341614T1 (de) 2006-10-15
AR063315A2 (es) 2009-01-21
PL197747B1 (pl) 2008-04-30
SK11842000A3 (sk) 2001-05-10
HK1097413A1 (en) 2007-06-22
DE69936948D1 (de) 2007-10-04
BR9908015A (pt) 2001-04-24
KR100918187B1 (ko) 2009-09-22
AU757976B2 (en) 2003-03-13
CN101164623A (zh) 2008-04-23
HUP0100670A2 (hu) 2001-06-28
EP1054955A2 (en) 2000-11-29
EP1741777A1 (en) 2007-01-10
CA2723040A1 (en) 1999-08-19
CA2320419A1 (en) 1999-08-19
EP1526173B1 (en) 2012-11-21
DE69936948T2 (de) 2008-05-15
EP1526174A3 (en) 2005-08-31
EP1526174A2 (en) 2005-04-27
WO1999041416A3 (en) 1999-11-18
JP4358434B2 (ja) 2009-11-04
HK1028416A1 (en) 2001-02-16
KR20010072547A (ko) 2001-07-31
EP1526173A3 (en) 2005-08-10
PE20000265A1 (es) 2000-04-25
DE69933433T2 (de) 2007-08-23
AR063314A2 (es) 2009-01-21
DE69933433D1 (de) 2006-11-16
KR20090038927A (ko) 2009-04-21
EP1741777B1 (en) 2010-08-25
JP2002503484A (ja) 2002-02-05
JP2006166925A (ja) 2006-06-29
HK1073481A1 (en) 2005-10-07

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