ATE341614T1 - Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten - Google Patents

Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten

Info

Publication number
ATE341614T1
ATE341614T1 AT99906690T AT99906690T ATE341614T1 AT E341614 T1 ATE341614 T1 AT E341614T1 AT 99906690 T AT99906690 T AT 99906690T AT 99906690 T AT99906690 T AT 99906690T AT E341614 T1 ATE341614 T1 AT E341614T1
Authority
AT
Austria
Prior art keywords
virus
concentration
methods
containing compositions
preparations
Prior art date
Application number
AT99906690T
Other languages
English (en)
Inventor
Andreas Frei
Henry K H Kwan
Varda E Sandweiss
Gary J Vellekamp
Pui-Ho Yuen
Laureano L Bondoc Jr
Frederick William Porter Iv
John Chu-Tay Tang
Peter Ihnat
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE341614T1 publication Critical patent/ATE341614T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99906690T 1998-02-17 1999-02-12 Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten ATE341614T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2446298A 1998-02-17 1998-02-17
US7964398A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
ATE341614T1 true ATE341614T1 (de) 2006-10-15

Family

ID=26698472

Family Applications (3)

Application Number Title Priority Date Filing Date
AT04030395T ATE371020T1 (de) 1998-02-17 1999-02-12 Virusenthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten
AT99906690T ATE341614T1 (de) 1998-02-17 1999-02-12 Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten
AT06019642T ATE478945T1 (de) 1998-02-17 1999-02-12 Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04030395T ATE371020T1 (de) 1998-02-17 1999-02-12 Virusenthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06019642T ATE478945T1 (de) 1998-02-17 1999-02-12 Virus enthaltende zusammensetzungen und methoden zur konzentration von viruspräparaten

Country Status (24)

Country Link
EP (4) EP1741777B1 (de)
JP (3) JP4358434B2 (de)
KR (5) KR100862169B1 (de)
CN (2) CN101164623B (de)
AR (3) AR020054A1 (de)
AT (3) ATE371020T1 (de)
AU (1) AU757976B2 (de)
BR (1) BR9908015A (de)
CA (2) CA2723040A1 (de)
CO (1) CO4820440A1 (de)
DE (3) DE69933433T2 (de)
DK (1) DK1054955T3 (de)
ES (2) ES2290613T3 (de)
HU (1) HU226015B1 (de)
ID (1) ID28298A (de)
IL (2) IL137510A0 (de)
MY (1) MY141641A (de)
NO (1) NO20004104L (de)
PE (1) PE20000265A1 (de)
PL (1) PL197747B1 (de)
PT (1) PT1054955E (de)
SK (1) SK11842000A3 (de)
TW (1) TWI232107B (de)
WO (1) WO1999041416A2 (de)

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AU2005305347A1 (en) 2004-11-03 2006-05-18 Introgen Therapeutics Inc. Method of producing and purifying of adenoviral vectors
US7851218B2 (en) 2004-12-13 2010-12-14 Schering Corporation Cell lines for production of replication-defective adenovirus
CA2602944C (en) 2005-04-11 2015-08-11 Crucell Holland B.V. Virus purification using ultrafiltration
CN1961961B (zh) * 2005-11-11 2010-05-26 深圳市源兴生物医药科技有限公司 一种药物制剂及其制备方法
DE602006019916D1 (de) 2005-12-12 2011-03-10 Canji Inc Adenovirale expressionsvektoren mit einer expressionskassette im e1-bereich und einer inaktivierten e2b-polymerase
US7875446B2 (en) * 2006-04-20 2011-01-25 Wyeth Llc Purification processes for isolating purified vesicular stomatitis virus from cell culture
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HRP20250897T1 (hr) 2009-05-02 2025-09-26 Genzyme Corporation Genska terapija za neurodegenerativne poremećaje
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US9119813B2 (en) 2012-03-22 2015-09-01 Crucell Holland B.V. Vaccine against RSV
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KR102236497B1 (ko) 2013-04-25 2021-04-06 얀센 백신스 앤드 프리벤션 비.브이. 안정화된 가용성 예비융합 rsv f 폴리펩타이드
CN105408348B (zh) 2013-06-17 2021-07-06 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f多肽
US10280195B2 (en) * 2014-05-28 2019-05-07 Agency For Science, Technology And Research Virus reduction method
JP6735288B2 (ja) 2015-04-14 2020-08-05 ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. 双方向性プロモーターを有する2つの導入遺伝子を発現する組換えアデノウイルス
US10457708B2 (en) 2015-07-07 2019-10-29 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
EA039065B1 (ru) 2015-07-07 2021-11-29 Янссен Вэксинс Энд Превеншн Б.В. Вакцина против rsv
IL262108B2 (en) 2016-04-05 2023-04-01 Janssen Vaccines Prevention B V Soluble pre-fusion rsv f proteins are stabilized
JP7233928B2 (ja) 2016-04-05 2023-03-07 ヤンセン ファッシンズ アンド プリベンション ベーフェー Rsvに対するワクチン
CN109311946A (zh) 2016-05-30 2019-02-05 扬森疫苗与预防公司 稳定化的融合前rsv f蛋白
RU2745500C2 (ru) 2016-06-20 2021-03-25 Янссен Вэксинс Энд Превеншн Б.В. Эффективный и сбалансированный двунаправленный промотор
WO2018011196A1 (en) 2016-07-14 2018-01-18 Janssen Vaccines & Prevention B.V. Hpv vaccines
WO2018210871A1 (en) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
AU2018267971A1 (en) 2017-05-17 2019-11-07 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
WO2019021305A1 (en) * 2017-07-24 2019-01-31 Ella Foundation VACCINE AGAINST FOOT AND MOUTH DISEASE
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JP2023512519A (ja) 2020-01-31 2023-03-27 ベス イスラエル ディーコネス メディカル センター インコーポレイテッド コロナウイルス感染症を予防および処置するための組成物および方法-sars-cov-2ワクチン
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Also Published As

Publication number Publication date
CN1297478A (zh) 2001-05-30
MY141641A (en) 2010-05-31
HK1097413A1 (en) 2007-06-22
WO1999041416A2 (en) 1999-08-19
AU2653899A (en) 1999-08-30
EP1054955B1 (de) 2006-10-04
EP1526173A2 (de) 2005-04-27
HK1073481A1 (en) 2005-10-07
DK1054955T3 (da) 2007-01-15
HK1028416A1 (en) 2001-02-16
JP2006166925A (ja) 2006-06-29
HU226015B1 (en) 2008-02-28
KR101018992B1 (ko) 2011-03-07
PL342847A1 (en) 2001-07-16
KR20080065615A (ko) 2008-07-14
JP2002503484A (ja) 2002-02-05
DE69933433T2 (de) 2007-08-23
KR100862169B1 (ko) 2008-10-09
DE69933433D1 (de) 2006-11-16
AR063315A2 (es) 2009-01-21
CN101164623A (zh) 2008-04-23
KR20080065614A (ko) 2008-07-14
NO20004104L (no) 2000-10-17
AR020054A1 (es) 2002-04-10
AR063314A2 (es) 2009-01-21
EP1526174A3 (de) 2005-08-31
EP1526174B1 (de) 2007-08-22
KR100991683B1 (ko) 2010-11-04
CN101164623B (zh) 2012-11-14
CA2723040A1 (en) 1999-08-19
CA2320419C (en) 2011-02-08
DE69936948T2 (de) 2008-05-15
ATE478945T1 (de) 2010-09-15
EP1526173B1 (de) 2012-11-21
JP4358434B2 (ja) 2009-11-04
HUP0100670A2 (hu) 2001-06-28
DE69942708D1 (de) 2010-10-07
IL137510A0 (en) 2001-07-24
DE69936948D1 (de) 2007-10-04
PT1054955E (pt) 2007-01-31
EP1054955A2 (de) 2000-11-29
EP1741777A1 (de) 2007-01-10
EP1526173A3 (de) 2005-08-10
JP2010213727A (ja) 2010-09-30
ES2272053T3 (es) 2007-04-16
KR20090127947A (ko) 2009-12-14
TWI232107B (en) 2005-05-11
SK11842000A3 (sk) 2001-05-10
PE20000265A1 (es) 2000-04-25
BR9908015A (pt) 2001-04-24
WO1999041416A3 (en) 1999-11-18
CO4820440A1 (es) 1999-07-28
ATE371020T1 (de) 2007-09-15
CA2320419A1 (en) 1999-08-19
KR20090038927A (ko) 2009-04-21
ES2290613T3 (es) 2008-02-16
KR20010072547A (ko) 2001-07-31
KR100912362B1 (ko) 2009-08-19
EP1741777B1 (de) 2010-08-25
HUP0100670A3 (en) 2003-10-28
ID28298A (id) 2001-05-10
NO20004104D0 (no) 2000-08-16
PL197747B1 (pl) 2008-04-30
EP1526174A2 (de) 2005-04-27
IL137510A (en) 2012-10-31
KR100918187B1 (ko) 2009-09-22
CN100374551C (zh) 2008-03-12
AU757976B2 (en) 2003-03-13

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