AR033600A1 - Difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para preparar medicamentos - Google Patents

Difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para preparar medicamentos

Info

Publication number: AR033600A1
Authority: AR; Argentina
Prior art keywords: alkyl; phenyl; substituted; compounds; medications
Prior art date: 2000-12-21

Application number

ARP010105908A

Other languages

English (en)

Spanish (es)

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-21

Filing date

2001-12-19

Publication date

2003-12-26

2000-12-21 Priority claimed from DE10064402A external-priority patent/DE10064402A1/de

2001-12-19 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2003-12-26 Publication of AR033600A1 publication Critical patent/AR033600A1/es

Links

150000001875 compounds Chemical class 0.000 title abstract 4
239000003814 drug Substances 0.000 title abstract 4
229940079593 drug Drugs 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
229910052731 fluorine Inorganic materials 0.000 abstract 8
229910052794 bromium Inorganic materials 0.000 abstract 6
229910052801 chlorine Inorganic materials 0.000 abstract 6
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 4
229910052740 iodine Inorganic materials 0.000 abstract 4
125000000896 monocarboxylic acid group Chemical group 0.000 abstract 4
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 4
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
-1 COO- (C1-6) -alkyl Chemical group 0.000 abstract 2
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
239000011737 fluorine Substances 0.000 abstract 2
125000001153 fluoro group Chemical group F* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
VDOXIAUNJCHYRC-UHFFFAOYSA-N 1,3-diphenylazetidin-2-one Chemical compound O=C1C(C=2C=CC=CC=2)CN1C1=CC=CC=C1 VDOXIAUNJCHYRC-UHFFFAOYSA-N 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
230000000055 hyoplipidemic effect Effects 0.000 abstract 1
238000002483 medication Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000565 sulfonamide group Chemical group 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ARP010105908A 2000-12-21 2001-12-19 Difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para preparar medicamentos AR033600A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10064402A DE10064402A1 (de)	2000-12-21	2000-12-21	Diphenylazetidinonderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE10154518		2001-11-07

Publications (1)

Publication Number	Publication Date
AR033600A1 true AR033600A1 (es)	2003-12-26

Family

ID=26008044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP010105908A AR033600A1 (es)	2000-12-21	2001-12-19	Difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para preparar medicamentos

Country Status (23)

Country	Link
US (1)	US6703386B2 (cs)
EP (1)	EP1345924B1 (cs)
JP (1)	JP2004516289A (cs)
KR (1)	KR20030063462A (cs)
CN (1)	CN1221546C (cs)
AR (1)	AR033600A1 (cs)
AT (1)	ATE338039T1 (cs)
AU (1)	AU2002231688A1 (cs)
BR (1)	BR0116322A (cs)
CA (1)	CA2431995A1 (cs)
CZ (1)	CZ20031733A3 (cs)
DE (1)	DE50110906D1 (cs)
EE (1)	EE200300238A (cs)
HR (1)	HRP20030501A2 (cs)
HU (1)	HUP0401073A2 (cs)
IL (1)	IL156548A0 (cs)
MX (1)	MXPA03005019A (cs)
NO (1)	NO20032735L (cs)
NZ (1)	NZ526594A (cs)
PL (1)	PL362512A1 (cs)
SK (1)	SK7782003A3 (cs)
WO (1)	WO2002050060A1 (cs)
YU (1)	YU47803A (cs)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
PL364178A1 (en) *	2001-01-26	2004-12-13	Schering Corporation	Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
HU230253B1 (hu)	2001-01-26	2015-11-30	Merck Sharp & Dohme Corp	Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
DK1355644T3 (da)	2001-01-26	2006-10-23	Schering Corp	Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
IL156585A0 (en) *	2001-01-26	2004-01-04	Schering Corp	Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
US20020183305A1 (en) *	2001-01-26	2002-12-05	Schering Corporation	Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
AU2002241956A1 (en) *	2001-01-26	2002-08-06	Schering Corporation	Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
TWI291957B (en) *	2001-02-23	2008-01-01	Kotobuki Pharmaceutical Co Ltd	Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same
JP2005504091A (ja)	2001-09-21	2005-02-10	シェーリング　コーポレイション	ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US20030119808A1 (en) *	2001-09-21	2003-06-26	Schering Corporation	Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7176194B2 (en)	2002-06-19	2007-02-13	Sanofi-Aventis Deutschland Gmbh	Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
DE10227507A1 (de) *	2002-06-19	2004-01-08	Aventis Pharma Deutschland Gmbh	Kationisch substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US7671047B2 (en)	2002-06-19	2010-03-02	Sanofi-Aventis Deutschland Gmbh	Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
US7176193B2 (en)	2002-06-19	2007-02-13	Sanofi-Aventis Deutschland Gmbh	Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
DE10227508A1 (de) *	2002-06-19	2004-01-08	Aventis Pharma Deutschland Gmbh	Säuregruppen-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
GB0215579D0 (en) *	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
DE10303900A1 (de) *	2003-01-31	2004-08-12	Nutrinova Nutrition Specialties & Food Ingredients Gmbh	Cholesterinsenkendes Mittel, enthaltend Levane
WO2004043457A1 (en)	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
JP4589919B2 (ja)	2003-03-07	2010-12-01	シェーリングコーポレイション	高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7459442B2 (en)	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2517571C (en)	2003-03-07	2011-07-05	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja)	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
WO2005021497A2 (en) *	2003-08-28	2005-03-10	Microbia, Inc.	Tethered dimers and trimers of 1,4-diphenylazetidn-2-ones
EP1918000A2 (en)	2003-11-05	2008-05-07	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
ATE485267T1 (de) *	2003-12-23	2010-11-15	Astrazeneca Ab	Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung
RU2380360C2 (ru) *	2003-12-23	2010-01-27	Астразенека Аб	Дифенилазетидиноновые производные, обладающие активностью, ингибирующей всасывание холестерина
GB0329778D0 (en) *	2003-12-23	2004-01-28	Astrazeneca Ab	Chemical compounds
DE102004024454A1 (de) *	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1807070A1 (en) *	2004-09-29	2007-07-18	Schering Corporation	Combinations of substituted azetidinones and cb1 antagonists
CN102633730A (zh)	2004-12-03	2012-08-15	先灵公司	作为cb1拮抗剂的取代哌嗪
TW200738676A (en) *	2005-06-20	2007-10-16	Schering Corp	Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists
SA06270191B1 (ar)	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
JP2009528266A (ja) *	2006-01-18	2009-08-06	シェーリングコーポレイション	カンナビノイド受容体修飾因子
TW200811098A (en)	2006-04-27	2008-03-01	Astrazeneca Ab	Chemical compounds
EP2061767B1 (de)	2006-08-08	2014-12-17	Sanofi	Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
US20080103122A1 (en) *	2006-09-05	2008-05-01	Schering Corporation	Pharmaceutical combinations for lipid management and in the treatment of atherosclerosis and hepatic steatosis
WO2008130616A2 (en) *	2007-04-19	2008-10-30	Schering Corporation	Diaryl morpholines as cb1 modulators
CA2694264A1 (en) *	2007-06-28	2009-01-08	Intervet International B.V.	Substituted piperazines as cb1 antagonists
CA2692268A1 (en) *	2007-06-28	2009-01-08	Intervet International B.V.	Substituted piperazines as cb1 antagonists
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de)	2007-11-13	2009-07-23	Sanofi-Aventis Deutschland Gmbh	Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
UY31968A (es)	2008-07-09	2010-01-29	Sanofi Aventis	Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
EP2403848A1 (en)	2009-03-06	2012-01-11	Lipideon Biotechnology AG	Pharmaceutical hypocholesterolemic compositions
CN101993403B (zh)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	氮杂环丁酮类化合物及医药应用
KR20120060207A (ko)	2009-08-26	2012-06-11	사노피	신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
EP2582709B1 (de)	2010-06-18	2018-01-24	Sanofi	Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
EP2766349B1 (de)	2011-03-08	2016-06-01	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828994B2 (en)	2011-03-08	2014-09-09	Sanofi	Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (de)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de)	2011-03-08	2015-06-24	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683704B1 (de)	2011-03-08	2014-12-17	Sanofi	Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
AU2019318209B2 (en)	2018-08-10	2025-09-25	Diapin Therapeutics, Llc	Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2191455A1 (en) *	1994-06-20	1995-12-28	Wayne Vaccaro	Substituted azetidinone compounds useful as hypocholesterolemic agents
EP0876379A1 (en)	1996-01-17	1998-11-11	Novo Nordisk A/S	Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
IL128332A0 (en)	1996-08-30	2000-01-31	Novo Nordisk As	GLP-1 derivatives
DE19845402B4 (de) *	1998-10-02	2005-04-07	Aventis Pharma Deutschland Gmbh	Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP0869121B1 (de) *	1997-04-04	2004-06-09	Aventis Pharma Deutschland GmbH	Hypolipidämische Propanolaminderivate
RU2215004C2 (ru)	1997-07-16	2003-10-27	Ново Нордиск А/С	Конденсированное производное 1,2,4-тиадиазина, фармацевтическая композиция и способ получения лекарственного препарата
DE19845406C2 (de) *	1998-10-02	2001-10-18	Aventis Pharma Gmbh	Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

2001
- 2001-12-11 MX MXPA03005019A patent/MXPA03005019A/es active IP Right Grant
- 2001-12-11 WO PCT/EP2001/014533 patent/WO2002050060A1/de not_active Ceased
- 2001-12-11 SK SK778-2003A patent/SK7782003A3/sk unknown
- 2001-12-11 IL IL15654801A patent/IL156548A0/xx unknown
- 2001-12-11 AT AT01991821T patent/ATE338039T1/de not_active IP Right Cessation
- 2001-12-11 HU HU0401073A patent/HUP0401073A2/hu unknown
- 2001-12-11 HR HR20030501A patent/HRP20030501A2/xx not_active Application Discontinuation
- 2001-12-11 AU AU2002231688A patent/AU2002231688A1/en not_active Abandoned
- 2001-12-11 EP EP01991821A patent/EP1345924B1/de not_active Expired - Lifetime
- 2001-12-11 CZ CZ20031733A patent/CZ20031733A3/cs unknown
- 2001-12-11 NZ NZ526594A patent/NZ526594A/en unknown
- 2001-12-11 EE EEP200300238A patent/EE200300238A/xx unknown
- 2001-12-11 JP JP2002551556A patent/JP2004516289A/ja not_active Abandoned
- 2001-12-11 BR BR0116322-1A patent/BR0116322A/pt not_active IP Right Cessation
- 2001-12-11 KR KR10-2003-7008503A patent/KR20030063462A/ko not_active Withdrawn
- 2001-12-11 CN CNB018210430A patent/CN1221546C/zh not_active Expired - Fee Related
- 2001-12-11 DE DE50110906T patent/DE50110906D1/de not_active Expired - Lifetime
- 2001-12-11 PL PL01362512A patent/PL362512A1/xx not_active Application Discontinuation
- 2001-12-11 YU YU47803A patent/YU47803A/sh unknown
- 2001-12-11 CA CA002431995A patent/CA2431995A1/en not_active Abandoned
- 2001-12-19 AR ARP010105908A patent/AR033600A1/es unknown
- 2001-12-19 US US10/021,044 patent/US6703386B2/en not_active Expired - Lifetime
2003
- 2003-06-16 NO NO20032735A patent/NO20032735L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL156548A0 (en)	2004-01-04
KR20030063462A (ko)	2003-07-28
YU47803A (sh)	2006-05-25
CA2431995A1 (en)	2002-06-27
HRP20030501A2 (en)	2005-04-30
NO20032735L (no)	2003-08-06
NZ526594A (en)	2004-08-27
MXPA03005019A (es)	2003-09-25
CN1481378A (zh)	2004-03-10
ATE338039T1 (de)	2006-09-15
JP2004516289A (ja)	2004-06-03
EP1345924A1 (de)	2003-09-24
SK7782003A3 (en)	2003-12-02
BR0116322A (pt)	2003-10-14
CZ20031733A3 (cs)	2003-09-17
EE200300238A (et)	2003-08-15
US6703386B2 (en)	2004-03-09
US20020128253A1 (en)	2002-09-12
NO20032735D0 (no)	2003-06-16
HUP0401073A2 (hu)	2004-09-28
DE50110906D1 (de)	2006-10-12
AU2002231688A1 (en)	2002-07-01
EP1345924B1 (de)	2006-08-30
CN1221546C (zh)	2005-10-05
PL362512A1 (en)	2004-11-02
WO2002050060A1 (de)	2002-06-27
HK1060119A1 (en)	2004-07-30

Legal Events

Date	Code	Title	Description
2006-07-12	FB	Suspension of granting procedure

Publication	Publication Date	Title
AR033600A1 (es)	2003-12-26	Difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para preparar medicamentos
AR034282A1 (es)	2004-02-18	Derivados de difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para la preparacion de medicamentos
AR040474A1 (es)	2005-04-06	Derivados de tiofenolglicosido, procedimientos para la preparacion de los mismos, medicamentos que contienen estos compuestos, y el uso de los mismos
AR039690A1 (es)	2005-03-09	Difenilazetidinonas sustituidas por grupos acidos, medicamentos que comprenden estos compuestos y su uso
HRP20080023T3 (en)	2008-06-30	Novel fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof
DK1585739T3 (da)	2011-06-20	Substituerede arylcyclopropylacetamider som glucokinaseaktivatorer
MXPA03011981A (es)	2004-06-03	3-fluoruro-pirrolidinas como agentes antidiabeticos.
EA200401056A1 (ru)	2005-04-28	Комбинация, содержащая производные тропана, полезные в терапии
BR0211472A (pt)	2004-11-09	Novos compostos
HUP0202655A2 (hu)	2002-11-28	N-[(amino-imino-metil)- és N-[(amino-metil)-fenil]-propil-amid származékok
ES2187983T3 (es)	2003-06-16	Derivados 1,2,3,4-tetrahidronaftaleno sustituidos.
SE0102616D0 (sv)	2001-07-25	Novel compounds
CO5140087A1 (es)	2002-03-22	Derivados de 3-fenil-piridina su procedimiento de sintesis y medicamentos que los contienen
HUP0400206A2 (hu)	2004-08-30	Metalloproteináz inhibitor hatású imidazolidin-dion-származékok, ezek alkalmazása gyógyszerkészítmények előállítására és ezeket tartalmazó gyógyszerkészítmények
CA2508226A1 (en)	2004-06-24	Novel heterocyclic fluoroglycoside derivatives, pharmaceutical products containing said compounds and the use thereof
DK1109813T3 (da)	2004-12-20	Pyrroloindoler, pyridoindoler og azepinoindoler som 5-HT2C-agonister
WO2003106428A8 (fr)	2004-05-06	Derives d'arylsulfonamides et leur utilisation en tant que antagonistes au recepteur b1 de la bradykinine
CO4930276A1 (es)	2000-06-27	Nuevos derivados de aminofosfohato y proceso de prepara cion
AR014868A1 (es)	2001-04-11	UN COMPUESTO DERIVADO DE N,N ( SUSTITUIDO) FENIL (ARILO O HETEROARILO) PROPANAMINA, UNA COMPOSICIoN FARMACÉUTICA, USO DE DICHO COMPUESTO Y UN MÉTODO PARA PREPARARLO.
AR028914A1 (es)	2003-05-28	2-guanidino-4-aril-quinazolinas como inhibidores de nhe-3
CO5540284A2 (es)	2005-07-29	Sulfonamidas
ATE175661T1 (de)	1999-01-15	Benzamid-derivate als vasopressin-antagonisten
CO5261565A1 (es)	2003-03-31	Inhibidores de n-(5-(((5-alquil-2-oxazolil)metil)tio)-2-tiazolil)-carboxamida de cinasas dependientes de ciclina
UY27244A1 (es)	2002-07-31	Uso del acido- (4´-trifluormetilfenil) - amida (z) -2- ciano-3- hidroxi-but-2-enoico para el tratamiento de la esclerosis multiple
HRP20070286T3 (en)	2007-08-31	Substituted diketopiperazines and their use as oxytocyn antagonists