AR041132A1 - Derivados de aminoindazol utilizados como medicamentos y composiciones farmaceuticas que los contienen - Google Patents

Derivados de aminoindazol utilizados como medicamentos y composiciones farmaceuticas que los contienen

Info

Publication number: AR041132A1
Authority: AR; Argentina
Prior art keywords: alkyl; heteroaryl; aryl; nhc; nr10r11
Prior art date: 2002-12-12

Application number

ARP030103187A

Other languages

English (en)

Spanish (es)

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-12

Filing date

2003-09-03

Publication date

2005-05-04

2003-09-03 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-05-04 Publication of AR041132A1 publication Critical patent/AR041132A1/es

Links

239000000203 mixture Substances 0.000 title abstract 2
YDTDKKULPWTHRV-UHFFFAOYSA-N 1H-indazol-3-amine Chemical class C1=CC=C2C(N)=NNC2=C1 YDTDKKULPWTHRV-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000001072 heteroaryl group Chemical group 0.000 abstract 8
125000003118 aryl group Chemical group 0.000 abstract 7
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052736 halogen Inorganic materials 0.000 abstract 5
150000002367 halogens Chemical class 0.000 abstract 5
125000000896 monocarboxylic acid group Chemical group 0.000 abstract 5
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 5
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
-1 aryl (C1-6) alkyl Chemical group 0.000 abstract 4
125000001424 substituent group Chemical group 0.000 abstract 4
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 4
125000003342 alkenyl group Chemical group 0.000 abstract 3
125000000304 alkynyl group Chemical group 0.000 abstract 3
125000000753 cycloalkyl group Chemical group 0.000 abstract 3
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 3
125000000623 heterocyclic group Chemical group 0.000 abstract 3
150000003254 radicals Chemical class 0.000 abstract 3
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000005592 polycycloalkyl group Polymers 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000005840 aryl radicals Chemical class 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000000335 thiazolyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Immunology (AREA)
Hematology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ARP030103187A 2002-12-12 2003-09-03 Derivados de aminoindazol utilizados como medicamentos y composiciones farmaceuticas que los contienen AR041132A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0215720A FR2848554A1 (fr)	2002-12-12	2002-12-12	Nouveaux derives d'aminoindazoles a titre de medicaments et compositions pharmaceutiques les renfermant

Publications (1)

Publication Number	Publication Date
AR041132A1 true AR041132A1 (es)	2005-05-04

Family

ID=32338720

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP030103187A AR041132A1 (es)	2002-12-12	2003-09-03	Derivados de aminoindazol utilizados como medicamentos y composiciones farmaceuticas que los contienen

Country Status (11)

Country	Link
JP (1)	JP4764168B2 (de)
CN (2)	CN1713909A (de)
AR (1)	AR041132A1 (de)
AT (1)	ATE520399T1 (de)
FR (1)	FR2848554A1 (de)
ME (1)	MEP25308A (de)
MY (1)	MY138085A (de)
PE (2)	PE20091629A1 (de)
RS (1)	RS20050421A (de)
TW (1)	TWI345561B (de)
ZA (1)	ZA200504681B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102007002717A1 (de)	2007-01-18	2008-07-24	Merck Patent Gmbh	Heterocyclische Indazolderivate
DE102007022565A1 (de)	2007-05-14	2008-11-20	Merck Patent Gmbh	Heterocyclische Indazolderivate
PT2401270E (pt) *	2009-02-26	2014-01-20	Glaxo Group Ltd	Derivados de pirazole utilizados como antagonistas do receptor ccr4
US10273252B2 (en)	2015-06-15	2019-04-30	Ube Industries, Ltd.	Substituted dihydropyrrolopyrazole derivative
CN115260165B (zh) *	2021-04-29	2024-08-06	中国科学院上海药物研究所	苯并含氮五元杂环化合物及其合成和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS51143010A (en) *	1975-06-04	1976-12-09	Kao Corp	Stable bleaching detergent composition
ES2266258T3 (es) *	2000-09-15	2007-03-01	Vertex Pharmaceuticals Incorporated	Compuestos de pirazol utiles como inhibidores de proteina cinasas.
US6593349B2 (en) *	2001-03-19	2003-07-15	Icagen, Inc.	Bisarylamines as potassium channel openers
CZ2004359A3 (cs) *	2001-09-26	2004-09-15	Pharmacia Italia S.P.A.	Aminoindazolové deriváty aktivní jako inhibitory kinázy, způsob jejich přípravy a farmaceutické prostředky obsahující tyto deriváty
FR2836915B1 (fr) *	2002-03-11	2008-01-11	Aventis Pharma Sa	Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
KR101166745B1 (ko) *	2002-09-05	2012-07-23	아방티 파르마 소시에테 아노님	의약으로서의 신규한 아미노인다졸 유도체 및 이를 함유하는 약제학적 조성물

2002
- 2002-12-12 FR FR0215720A patent/FR2848554A1/fr active Pending
2003
- 2003-09-01 PE PE2009001071A patent/PE20091629A1/es not_active Application Discontinuation
- 2003-09-01 PE PE2003000886A patent/PE20040996A1/es not_active Application Discontinuation
- 2003-09-03 AR ARP030103187A patent/AR041132A1/es unknown
- 2003-09-03 AT AT03769560T patent/ATE520399T1/de not_active IP Right Cessation
- 2003-09-03 ME MEP-253/08A patent/MEP25308A/xx unknown
- 2003-09-03 CN CNA038256169A patent/CN1713909A/zh active Pending
- 2003-09-03 JP JP2005512867A patent/JP4764168B2/ja not_active Expired - Fee Related
- 2003-09-03 CN CN2010105043043A patent/CN101979382A/zh active Pending
- 2003-09-03 RS YUP-2005/0421A patent/RS20050421A/sr unknown
- 2003-09-04 MY MYPI20033346A patent/MY138085A/en unknown
- 2003-09-04 TW TW092124409A patent/TWI345561B/zh not_active IP Right Cessation
2005
- 2005-06-08 ZA ZA200504681A patent/ZA200504681B/en unknown

Also Published As

Publication number	Publication date
CN101979382A (zh)	2011-02-23
TW200422293A (en)	2004-11-01
TWI345561B (en)	2011-07-21
ATE520399T1 (de)	2011-09-15
MY138085A (en)	2009-04-30
JP2006516266A (ja)	2006-06-29
ZA200504681B (en)	2006-08-30
RS20050421A (sr)	2007-08-03
JP4764168B2 (ja)	2011-08-31
PE20091629A1 (es)	2009-11-16
PE20040996A1 (es)	2005-01-28
CN1713909A (zh)	2005-12-28
MEP25308A (en)	2010-06-10
FR2848554A1 (fr)	2004-06-18

Legal Events

Date	Code	Title	Description
2012-04-27	FB	Suspension of granting procedure

Publication	Publication Date	Title
AR038915A1 (es)	2005-02-02	Derivados de aminoindazoles, procedimiento de preparacion e intermedios de este procedimiento, medicamentos y composiciones farmaceuticas que contienen al compuesto
AR045462A1 (es)	2005-10-26	DERIVADOS DE INDOLES SUSTITUIDOS eTILES COMO COMPUESTOS FARMACEUTICOS PARA EL TRATAMIENTO DE ENFERMEDADES RESPIRATORIAS
AR039933A1 (es)	2005-03-09	Indoles sustituidos para tratamiento de desordenes respiratorios
AR064258A1 (es)	2009-03-25	Inhibidores macrociclicos del virus de hepatitis c
AR058769A1 (es)	2008-02-20	Inhibidores de peptidil-deformilasa(pdf),utiles para el tratamiento de la tuberculosis y composiciones farmaceuticas que los contienen.
AR039934A1 (es)	2005-03-09	Indoles sustituidos para el tratamiento de desordenes respiratorios
AR044552A1 (es)	2005-09-21	Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios
AR046244A1 (es)	2005-11-30	Activadores de glucoquinasa heteroaromaticos de seis miembros 5- sustituidos
HUP0303652A2 (hu)	2004-03-01	Ciklikus származékok, mint kemokin receptor aktivitás modulátorai és ezeket tartalmazó gyógyszerkészítmények
CO5280046A1 (es)	2003-05-30	Agonistas alfa 7 y sus composiciones farmaceuticas
AR039403A1 (es)	2005-02-16	Derivados de acil-4-carboxifenilurea y su uso como antidiabetico
AR049739A1 (es)	2006-08-30	Derivados de aril-piridina
AR042024A1 (es)	2005-06-08	Compuestos farmaceuticos derivados de piridona, pirimidona y pirazinona
AR055592A1 (es)	2007-08-29	Derivados de 2-amino-5-cicloalquil-hidantoina como moduladores y/o inhibidores de la beta-secretasa(bace)
CO5601012A2 (es)	2006-01-31	Compuestos que modulan la actividad de ppar
ATE455119T1 (de)	2010-01-15	Thiazolo-, oxazalo und imidazolo- chinazolinverbindungen, die dazu fähig sind, proteinkinasen zu hemmen
HUP0402529A2 (hu)	2005-03-29	Xa faktor és más, a koagulációs kaszkádban részt vevő szerin-proteázok inhibitorai, eljárás előállításukra és ezeket hatóanyagként tartalmazó gyógyszerkészítmények
HUP0201988A2 (hu)	2002-11-28	N-(indolkarbonil)piperazin-származékok
AR053405A1 (es)	2007-05-09	Derivados de urea sustituidas, composiciones farmaceuticas y metodos para el tratamiento de cardiopatias
AR040498A1 (es)	2005-04-06	Indoles sustituidos utiles para el tratamiento de enfermedades respiratorias
AR042851A1 (es)	2005-07-06	Acidos hidroxamicos inhibidores de histona desacetilasa
CO5251467A1 (es)	2003-02-28	Derivados de piperazina
AR066561A1 (es)	2009-08-26	Derivados de imidazol, composiciones farmaceuticas y usos
MXPA03010584A (es)	2004-03-09	Derivados de tiazol u oxazol que son utiles en el tratamiento de enfermedades cardiovasculares y relacionadas.
AR040338A1 (es)	2005-03-30	Uso de derivados de tio-oxindol en el tratamiento de trastornos de la piel