AR044246A1 - Vectores y celulas para la preparacion de composiciones inmunoprotectoras derivadas de plantas transgenicas - Google Patents

Vectores y celulas para la preparacion de composiciones inmunoprotectoras derivadas de plantas transgenicas

Info

Publication number
AR044246A1
AR044246A1 ARP040101521A ARP040101521A AR044246A1 AR 044246 A1 AR044246 A1 AR 044246A1 AR P040101521 A ARP040101521 A AR P040101521A AR P040101521 A ARP040101521 A AR P040101521A AR 044246 A1 AR044246 A1 AR 044246A1
Authority
AR
Argentina
Prior art keywords
preparation
vectors
cells
immunoprotector
transgenic plants
Prior art date
Application number
ARP040101521A
Other languages
English (en)
Original Assignee
Dow Agrosciences Llc
Thompson Boyce Plant Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc, Thompson Boyce Plant Res filed Critical Dow Agrosciences Llc
Publication of AR044246A1 publication Critical patent/AR044246A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente se refiere a la producción de vectores y métodos útiles para la preparación de células de plantas genéticamente transformadas que expresan inmunógenos de organismos patógenos los cuales son utilizados para producir partículas inmunoprotectoras útiles en la preparación de vacunas, incluye genes vegetales optimizados que codifican la proteína HN del virus de la enfermedad de Newcastle, también se refiere a métodos de producción de un antígeno en una planta transgénica. Reivindicación 1: Una secuencia nucleotídica optimizada vegetal aislada que codifica el antígeno HN del virus de la enfermedad de Newcastle que comprende la secuencia de SEQ ID Nº:1.
ARP040101521A 2003-05-05 2004-05-05 Vectores y celulas para la preparacion de composiciones inmunoprotectoras derivadas de plantas transgenicas AR044246A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46799803P 2003-05-05 2003-05-05

Publications (1)

Publication Number Publication Date
AR044246A1 true AR044246A1 (es) 2005-09-07

Family

ID=33435152

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040101521A AR044246A1 (es) 2003-05-05 2004-05-05 Vectores y celulas para la preparacion de composiciones inmunoprotectoras derivadas de plantas transgenicas

Country Status (13)

Country Link
US (3) US7132291B2 (es)
EP (1) EP1620550B1 (es)
KR (1) KR20060035596A (es)
CN (1) CN100393870C (es)
AR (1) AR044246A1 (es)
AT (1) ATE473271T1 (es)
AU (1) AU2004235813B2 (es)
BR (1) BRPI0410340A (es)
CA (1) CA2524293A1 (es)
DE (1) DE602004028004D1 (es)
NZ (1) NZ543348A (es)
WO (1) WO2004098533A2 (es)
ZA (1) ZA200508930B (es)

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JP2009540801A (ja) * 2006-06-16 2009-11-26 ダウ・アグロサイエンス・エル・エル・シー トリインフルエンザ赤血球凝集素の新規なｄｎａ配列、ベクターおよびタンパク質
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CN101687024A (zh) * 2007-04-28 2010-03-31 美国弗劳恩霍夫股份有限公司 锥虫抗原、疫苗组合物和相关方法
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US8404252B2 (en) 2007-07-11 2013-03-26 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
WO2009076778A1 (en) * 2007-11-27 2009-06-25 Medicago Inc. Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin
CA2615372A1 (en) * 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
CA2696764A1 (en) * 2007-08-20 2009-02-26 Fraunhofer Usa, Inc. Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods
EA034733B1 (ru) * 2008-01-21 2020-03-13 Медикаго Инк. Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение
WO2010003235A1 (en) * 2008-07-08 2010-01-14 Medicago Inc. Soluble recombinant influenza antigens
DK2318530T3 (en) 2008-07-18 2016-10-03 Medicago Inc Ny epitope to immunization against influenza
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US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
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Also Published As

Publication number Publication date
EP1620550B1 (en) 2010-07-07
US7407802B2 (en) 2008-08-05
WO2004098533A2 (en) 2004-11-18
US20090017065A1 (en) 2009-01-15
US20080076177A1 (en) 2008-03-27
EP1620550A4 (en) 2006-06-14
US20050048074A1 (en) 2005-03-03
ATE473271T1 (de) 2010-07-15
CN1788077A (zh) 2006-06-14
AU2004235813A1 (en) 2004-11-18
BRPI0410340A (pt) 2006-05-30
DE602004028004D1 (de) 2010-08-19
EP1620550A2 (en) 2006-02-01
CA2524293A1 (en) 2004-11-18
ZA200508930B (en) 2007-03-28
KR20060035596A (ko) 2006-04-26
WO2004098533A3 (en) 2005-08-04
NZ543348A (en) 2008-08-29
US7132291B2 (en) 2006-11-07
AU2004235813B2 (en) 2010-07-29
CN100393870C (zh) 2008-06-11

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