BRPI0410340A - vetores e células para preparar composições imunoprotetoras derivadas de plantas transgênicas - Google Patents

vetores e células para preparar composições imunoprotetoras derivadas de plantas transgênicas

Info

Publication number
BRPI0410340A
BRPI0410340A BRPI0410340-8A BRPI0410340A BRPI0410340A BR PI0410340 A BRPI0410340 A BR PI0410340A BR PI0410340 A BRPI0410340 A BR PI0410340A BR PI0410340 A BRPI0410340 A BR PI0410340A
Authority
BR
Brazil
Prior art keywords
vectors
cells
derived
transgenic plant
preparing
Prior art date
Application number
BRPI0410340-8A
Other languages
English (en)
Inventor
Guy A Cardineau
Hugh Stanley Mason
Joyce M Vaneck
Dwayne D Kirk
Amanda Maree Walmsley
Original Assignee
Dow Agrosciences Llc
Thompson Boyce Plant Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc, Thompson Boyce Plant Res filed Critical Dow Agrosciences Llc
Publication of BRPI0410340A publication Critical patent/BRPI0410340A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"VETORES E CéLULAS PARA PREPARAR COMPOSIçõES IMUNOPROTETORAS DERIVADAS DE PLANTAS TRANSGêNICAS". A invenção é dirigida aos vetores e aos métodos úteis para preparar células de plantas geneticamente transformadas, que expressam imunógenos de organismos patogênicos que são usados para produzir partículas imunoprotetoras úteis em preparações de vacinas. A invenção inclui os genes otimizados em plantas que codificam a proteína HN do Vírus da Doença de Newcastle. A invenção também se relaciona aos métodos de produzir um antígeno em uma planta transgênica.
BRPI0410340-8A 2003-05-05 2004-05-04 vetores e células para preparar composições imunoprotetoras derivadas de plantas transgênicas BRPI0410340A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46799803P 2003-05-05 2003-05-05
PCT/US2004/014182 WO2004098533A2 (en) 2003-05-05 2004-05-04 Vectors and cells for preparing immunoprotective compositions derived from transgenic plants

Publications (1)

Publication Number Publication Date
BRPI0410340A true BRPI0410340A (pt) 2006-05-30

Family

ID=33435152

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410340-8A BRPI0410340A (pt) 2003-05-05 2004-05-04 vetores e células para preparar composições imunoprotetoras derivadas de plantas transgênicas

Country Status (13)

Country Link
US (3) US7132291B2 (pt)
EP (1) EP1620550B1 (pt)
KR (1) KR20060035596A (pt)
CN (1) CN100393870C (pt)
AR (1) AR044246A1 (pt)
AT (1) ATE473271T1 (pt)
AU (1) AU2004235813B2 (pt)
BR (1) BRPI0410340A (pt)
CA (1) CA2524293A1 (pt)
DE (1) DE602004028004D1 (pt)
NZ (1) NZ543348A (pt)
WO (1) WO2004098533A2 (pt)
ZA (1) ZA200508930B (pt)

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CN1326998C (zh) * 2004-11-25 2007-07-18 中国农业科学院哈尔滨兽医研究所 编码h5亚型禽流感病毒血凝素蛋白的基因及其应用
EP1919504B1 (en) 2005-08-03 2013-10-16 iBio, Inc. Antibody to bacillus anthracis protective antigen
JP2009514547A (ja) 2005-11-04 2009-04-09 ダウ・アグロサイエンス・エル・エル・シー 組み換え植物懸濁培養物を使用するワクチンマスター細胞系統の調製
US8277816B2 (en) * 2006-02-13 2012-10-02 Fraunhofer Usa, Inc. Bacillus anthracis antigens, vaccine compositions, and related methods
WO2007095320A2 (en) * 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Hpv antigens, vaccine compositions, and related methods
AU2007215080A1 (en) * 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
JP2009535306A (ja) * 2006-04-21 2009-10-01 ダウ・アグロサイエンス・エル・エル・シー 鳥インフルエンザに対するワクチンおよび使用方法
KR100766775B1 (ko) * 2006-04-24 2007-11-01 대한민국 장출혈성대장균(ｅｈｅｃ) 감염증 예방용 톡소이드 백신
CN100487119C (zh) * 2006-05-09 2009-05-13 中国农业科学院哈尔滨兽医研究所 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株
EP2029167A4 (en) * 2006-06-16 2010-06-16 Dow Agrosciences Llc NEW DNA SEQUENCES, VECTORS AND PROTEINS OF BIRD FLUID HEMOGGLUTININE
US20080241188A1 (en) * 2007-03-30 2008-10-02 Zeon Corporation Turkey herpesvirus vectored recombinant containing avian influenza genes
BRPI0810865A2 (pt) * 2007-04-28 2017-05-09 Fraunhofer Usa Inc antígenos de tripanossoma, composições vacinais, e métodos relacionados
BRPI0812538B1 (pt) * 2007-06-15 2021-03-16 Medicago Inc. processo para a síntese de uma proteína de interesse com fucosilação e xilosilação reduzidas, ácido nucleico, e proteína híbrida gnt1-galt
KR100964462B1 (ko) * 2007-07-10 2010-06-16 성균관대학교산학협력단 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법
US8404252B2 (en) * 2007-07-11 2013-03-26 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
CA2615372A1 (en) * 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
CN101820903A (zh) * 2007-08-20 2010-09-01 美国弗劳恩霍夫股份有限公司 预防性和治疗性流感疫苗、抗原、组合物和方法
EP2610345B1 (en) * 2007-11-27 2015-08-19 Medicago Inc. Recombinant influenza virus-like particles (VLPS) produced in transgenic plants expressing hemagglutinin
EA034733B1 (ru) 2008-01-21 2020-03-13 Медикаго Инк. Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение
DK2294202T3 (en) 2008-07-08 2015-08-31 Medicago Inc SOLUBLE RECOMBINANT INFLUENZA ANTIGENES
JP5813505B2 (ja) 2008-07-18 2015-11-17 メディカゴ インコーポレイテッド 新規インフルエンザウイルス免疫エピトープ
WO2010037046A1 (en) 2008-09-28 2010-04-01 Fraunhofer Usa, Inc. Humanized neuraminidase antibody and methods of use thereof
US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
WO2010117786A1 (en) 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Influenza virus vaccines and uses thereof
DK2445928T3 (en) 2009-06-24 2018-05-28 Medicago Inc CHEMICAL INFLUENZA VIRUS-LIKE PARTICLES INCLUDING HEMAGGLUTIN
ES2642631T3 (es) 2009-09-22 2017-11-17 Medicago Inc. Método de preparación de VLP derivadas de plantas
EP2483307A1 (en) 2009-09-29 2012-08-08 Fraunhofer USA, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
EA030095B1 (ru) 2009-12-28 2018-06-29 ДиЭсЭм АйПи АССЕТС Б.В. Получение белка гемагглютинин-нейраминидазы в микроводорослях
WO2011090708A2 (en) 2009-12-28 2011-07-28 Merial Limited Recombinant ndv antigen and uses thereof
CN102939096B (zh) 2010-02-18 2016-03-02 西奈山医学院 用于预防和治疗流感病毒疾病的疫苗
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ES2953393T3 (es) 2011-09-20 2023-11-10 Icahn School Med Mount Sinai Vacunas contra el virus de la influenza y sus usos
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Also Published As

Publication number Publication date
EP1620550A4 (en) 2006-06-14
EP1620550B1 (en) 2010-07-07
DE602004028004D1 (de) 2010-08-19
ZA200508930B (en) 2007-03-28
ATE473271T1 (de) 2010-07-15
EP1620550A2 (en) 2006-02-01
CN100393870C (zh) 2008-06-11
US7132291B2 (en) 2006-11-07
US20080076177A1 (en) 2008-03-27
US20050048074A1 (en) 2005-03-03
AU2004235813A1 (en) 2004-11-18
CN1788077A (zh) 2006-06-14
WO2004098533A3 (en) 2005-08-04
NZ543348A (en) 2008-08-29
KR20060035596A (ko) 2006-04-26
CA2524293A1 (en) 2004-11-18
AR044246A1 (es) 2005-09-07
AU2004235813B2 (en) 2010-07-29
US20090017065A1 (en) 2009-01-15
WO2004098533A2 (en) 2004-11-18
US7407802B2 (en) 2008-08-05

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.