AR068043A1 - Uso de glicosaminoglicanos para reducir la union inespecifica en inmunoensayos - Google Patents

Uso de glicosaminoglicanos para reducir la union inespecifica en inmunoensayos

Info

Publication number
AR068043A1
AR068043A1 ARP080103711A ARP080103711A AR068043A1 AR 068043 A1 AR068043 A1 AR 068043A1 AR P080103711 A ARP080103711 A AR P080103711A AR P080103711 A ARP080103711 A AR P080103711A AR 068043 A1 AR068043 A1 AR 068043A1
Authority
AR
Argentina
Prior art keywords
analyte
glycosaminoglycan
sample
immunoensays
glycosaminoglycans
Prior art date
Application number
ARP080103711A
Other languages
English (en)
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39967577&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR068043(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of AR068043A1 publication Critical patent/AR068043A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Se proporciona un reactivo de inmunoensayo que comprende un agente de union al analito en un diluyente y un glicosaminoglicano en una cantidad suficiente para reducir la union inespecífica en un ensayo de una muestra con el analito. Se proporciona dicho inmunoensayo en que el analito es troponina 1, el agente de union al analito es un anticuerpo anti-troponina 1 biotinilado y el glicosaminoglicano es sulfato de condroitina. También se proporciona una composicion de muestra que comprende una muestra de ensayo para determinar la presencia de un analito, un agente de union al analito, y un glicosaminoglicano diferente de heparina. Además se proporciona un método para detectar un analito en una muestra, en el que se reduce la union inespecífica mediante un glicosaminoglicano.
ARP080103711A 2007-08-28 2008-08-27 Uso de glicosaminoglicanos para reducir la union inespecifica en inmunoensayos AR068043A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/846,390 US8617820B2 (en) 2007-08-28 2007-08-28 Use of glycosaminoglycans to reduce non-specific binding in immunoassays

Publications (1)

Publication Number Publication Date
AR068043A1 true AR068043A1 (es) 2009-10-28

Family

ID=39967577

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080103711A AR068043A1 (es) 2007-08-28 2008-08-27 Uso de glicosaminoglicanos para reducir la union inespecifica en inmunoensayos

Country Status (12)

Country Link
US (1) US8617820B2 (es)
EP (1) EP2031392B1 (es)
JP (1) JP5274934B2 (es)
KR (1) KR101557034B1 (es)
CN (1) CN101377488B (es)
AR (1) AR068043A1 (es)
AU (1) AU2008207454B2 (es)
BR (1) BRPI0803650A2 (es)
CA (1) CA2639196C (es)
CL (1) CL2008002525A1 (es)
ES (1) ES2525330T3 (es)
RU (1) RU2490648C2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010073182A1 (en) * 2008-12-22 2010-07-01 Koninklijke Philips Electronics N.V. Assay for troponin i using magnetic labels
CN103975241B (zh) * 2011-08-03 2016-01-20 奎德尔公司 用于提高a型链球菌免疫测定法的特异性的n-乙酰基-d-葡糖胺
WO2013161614A1 (ja) 2012-04-27 2013-10-31 コニカミノルタ株式会社 酵素処理工程を含むレクチンを用いた抗原検出方法
EP2940473B1 (en) * 2012-12-28 2018-08-01 Konica Minolta, Inc. Immunoassay method less affected by impurities
JP6414078B2 (ja) 2013-12-27 2018-10-31 コニカミノルタ株式会社 診断用情報の分析方法およびそのためのキット
US10222385B2 (en) 2013-12-27 2019-03-05 Konica Minolta, Inc. Methods for discriminating between prostate cancer and a benign prostate-disease
WO2015194350A1 (ja) 2014-06-20 2015-12-23 コニカミノルタ株式会社 標識化レクチンを用いるサンドイッチ型アッセイおよびそのためのキット
JP6651794B2 (ja) * 2015-11-05 2020-02-19 富士レビオ株式会社 心筋トロポニンｉ測定試薬及び方法
ES2910089T3 (es) * 2016-04-13 2022-05-11 Lsi Medience Corp Inmunoensayo que emplea polisacárido sulfatado
EP3574324A2 (en) 2017-01-27 2019-12-04 Roche Diagnostics GmbH Methods for modulating signal intensity in interaction assays
EP3593122A4 (en) * 2017-03-07 2021-01-06 Ortho-Clinical Diagnostics, Inc. METHOD OF DETECTION OF ANALYTES
US20200048723A1 (en) * 2017-03-22 2020-02-13 Fujifilm Wako Pure Chemical Corporation Method for forming complex of substance having sugar chain and lectin
CA3203751A1 (en) * 2020-12-03 2022-06-09 Ortho-Clinical Diagnostics, Inc. Lithium heparin as a blocking agent
KR20230165290A (ko) 2021-04-01 2023-12-05 벡톤 디킨슨 앤드 컴퍼니 그룹 a 연쇄상구균 면역검정의 특이성 및 민감도를 향상시키기 위한 방법들
CN113671195A (zh) * 2021-09-13 2021-11-19 迈克生物股份有限公司 抗双链dna抗体检测试剂盒及其应用

Family Cites Families (19)

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JPH02238361A (ja) 1989-03-10 1990-09-20 Sekisui Chem Co Ltd 免疫反応測定法および免疫反応測定用試薬
DE3922873A1 (de) * 1989-04-25 1990-10-31 Boehringer Mannheim Gmbh Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen
US5529985A (en) * 1990-04-23 1996-06-25 Akzo Nobel Nv Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
WO1992021769A1 (en) 1991-05-30 1992-12-10 Abbott Laboratories Reagents containing a nonspecific binding blocker in ion-capture binding assays
FR2718849B1 (fr) * 1994-04-14 1996-06-14 Pasteur Sanofi Diagnostics Procédé d'immunodosage de l'antithrombine III activée par un glycosaminoglycane, anticorps monoclonaux correspondants et leur procédé d'obtention.
JP2649016B2 (ja) 1994-07-15 1997-09-03 三洋化成工業株式会社 免疫反応干渉作用の除去方法
AU3483395A (en) 1994-09-28 1996-04-19 Spectral Diagnostics Inc. A monoclonal antibody to human cardiac troponin i
US5639626A (en) * 1994-11-15 1997-06-17 Chiron Diagnostics Corporation Reagents for specific binding assays
US6627404B1 (en) * 1995-04-18 2003-09-30 Biosite, Inc. Methods for improving the recovery of troponin I and T in membranes, filters and vessels
US6991907B1 (en) * 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
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RU2122736C1 (ru) * 1996-01-31 1998-11-27 Научно-технический центр "Лекбиотех" Набор для выявления сенсибилизирующих аллергенов методом твердофазного иммуноферментного анализа
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WO2007058654A1 (en) * 2005-11-17 2007-05-24 Siemens Healthcare Diagnostics Inc. Reduction of non-specific binding in assays

Also Published As

Publication number Publication date
RU2490648C2 (ru) 2013-08-20
RU2008135060A (ru) 2010-03-10
US20090061455A1 (en) 2009-03-05
EP2031392B1 (en) 2014-09-24
ES2525330T3 (es) 2014-12-22
CL2008002525A1 (es) 2009-01-16
CA2639196A1 (en) 2009-02-28
US8617820B2 (en) 2013-12-31
JP2009053195A (ja) 2009-03-12
HK1130089A1 (en) 2009-12-18
KR20090023223A (ko) 2009-03-04
AU2008207454B2 (en) 2015-03-26
BRPI0803650A2 (pt) 2009-05-05
CA2639196C (en) 2016-07-19
CN101377488B (zh) 2015-04-01
CN101377488A (zh) 2009-03-04
JP5274934B2 (ja) 2013-08-28
AU2008207454A1 (en) 2009-03-19
KR101557034B1 (ko) 2015-10-02
EP2031392A1 (en) 2009-03-04

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