AR241185A1 - Procedimiento para la preparacion de derivados de acilaminometil-3-imidazo¡1,2-a¿piridinas. - Google Patents

Procedimiento para la preparacion de derivados de acilaminometil-3-imidazo¡1,2-a¿piridinas.

Info

Publication number: AR241185A1
Authority: AR; Argentina
Prior art keywords: formula; methyl; phenyl; alkyl; pyridines
Prior art date: 1984-08-07

Application number

AR85301203A

Other languages

English (en)

Spanish (es)

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-07

Filing date

1985-08-06

Publication date

1992-01-31

1985-08-06 Application filed by Synthelabo filed Critical Synthelabo

1992-01-31 Application granted granted Critical

1992-01-31 Publication of AR241185A1 publication Critical patent/AR241185A1/es

Links

150000003222 pyridines Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
-1 METHYL SULPHONYL Chemical class 0.000 abstract 3
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 3
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AR85301203A 1984-08-07 1985-08-06 Procedimiento para la preparacion de derivados de acilaminometil-3-imidazo¡1,2-a¿piridinas. AR241185A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8412447A FR2568880B1 (fr)	1984-08-07	1984-08-07	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
AR241185A1 true AR241185A1 (es)	1992-01-31

Family

ID=9306856

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AR85301203A AR241185A1 (es)	1984-08-07	1985-08-06	Procedimiento para la preparacion de derivados de acilaminometil-3-imidazo¡1,2-a¿piridinas.

Country Status (23)

Country	Link
US (1)	US4650796A (2)
EP (1)	EP0172096B1 (2)
JP (1)	JPS6147485A (2)
KR (1)	KR910004450B1 (2)
AR (1)	AR241185A1 (2)
AT (1)	ATE40365T1 (2)
AU (1)	AU575190B2 (2)
CA (1)	CA1261830A (2)
CZ (1)	CZ357691A3 (2)
DE (1)	DE3567867D1 (2)
DK (1)	DK163923C (2)
ES (1)	ES8604592A1 (2)
FI (1)	FI80696C (2)
FR (1)	FR2568880B1 (2)
GR (1)	GR851928B (2)
HU (1)	HU193799B (2)
IE (1)	IE58347B1 (2)
IL (1)	IL76020A (2)
MX (1)	MX160845A (2)
NO (1)	NO162189C (2)
NZ (1)	NZ213013A (2)
PT (1)	PT80921B (2)
ZA (1)	ZA855939B (2)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2593180B1 (fr) *	1986-01-22	1990-10-26	Synthelabo	Derives d'acylaminomethyl-1 imidazo (1,2-a)quinoleines, leur preparation et leur application en therapeutique
FR2593818B1 (fr) *	1986-02-05	1988-04-29	Synthelabo	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
ES2032455T3 (es) *	1986-01-22	1993-02-16	Synthelabo	Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
US4990506A (en) *	1986-02-05	1991-02-05	Synthelabo	3-(acylaminomethyl)imidazo[1,2-a]pyridine derivatives and their application in therapy
FR2606409B1 (fr) *	1986-11-07	1989-05-05	Synthelabo	Derives d'imidazopyridine, leur preparation et leur application en therapeutique
DE3865073D1 (de) *	1987-03-27	1991-10-31	Synthelabo	Imidazopyridinderivate, ihre herstellung und therapeutische verwendung.
FR2615513B1 (fr) *	1987-05-21	1989-07-13	Synthelabo	Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2654933B1 (fr) *	1989-11-30	1994-06-10	Synthelabo	Utilisation d'une imidazopyridine pour la fabrication de medicaments anesthesiques.
US5716964A (en) *	1989-12-04	1998-02-10	G.D. Searle & Co.	Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
KR910011852A (ko) *	1989-12-04	1991-08-07	폴 디. 매튜카이티스	신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
IE904346A1 (en) *	1989-12-04	1991-06-05	Searle & Co	IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
US5464843A (en) *	1992-06-23	1995-11-07	G.D. Searle & Co.	Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AUPP278498A0 (en) *	1998-04-03	1998-04-30	Australian Nuclear Science & Technology Organisation	Peripheral benzodiazepine receptor binding agents
DE10019714A1 (de) *	2000-04-20	2002-01-10	Gruenenthal Gmbh	Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
AU2001270297A1 (en)	2000-06-30	2002-01-14	Neurogen Corporation	2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
DE10247269A1 (de)	2002-10-10	2004-04-22	Grünenthal GmbH	Substituierte C-Imidazo[1,2-a]pyridin-3-yl-methylamine
US7148353B2 (en) *	2003-10-28	2006-12-12	Sepracor Inc.	Imidazo[1,2-a] pyridine anxiolytics
WO2005081749A2 (en) *	2004-01-23	2005-09-09	Avanir Pharmaceuticals, Inc.	Neutralizing human antibodies to anthraxtoxin
FR2874611B1 (fr) *	2004-08-31	2006-11-17	Servier Lab	Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101065377B (zh) *	2004-11-11	2011-07-27	菲尔若国际公司	咪唑并[1,2-a]吡啶化合物、组合物、与其有关的应用和方法
JP2008542323A (ja)	2005-06-01	2008-11-27	ユセベファルマソシエテアノニム	２−オキソ−１−ピロリジン誘導体、その製造方法及びその使用
WO2008132142A2 (en) *	2007-04-27	2008-11-06	Ucb Pharma S.A.	New heterocyclic derivatives useful for the treatment of cns disorders
EP2300470A2 (en) *	2008-05-19	2011-03-30	Sepracor Inc.	Imidazo[1,2-a]pyridine compounds as gaba-a receptor modulators
DK2376490T3 (da) *	2008-12-04	2013-04-15	Proximagen Ltd	Imidazopyridinforbindelser
WO2014187922A1 (en)	2013-05-24	2014-11-27	Iomet Pharma Ltd.	Slc2a transporter inhibitors
US12282014B2 (en)	2015-11-19	2025-04-22	Dana-Farber Cancer Institute, Inc.	Methods of identifying compounds that interfere with ERG-driven misguidance of BAF complexes in TMPRSS2-ERG driven prostate cancers
US11497752B2 (en)	2018-01-30	2022-11-15	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2020081588A1 (en)	2018-10-17	2020-04-23	Dana-Farber Cancer Institute, Inc.	Swi/snf family chromatin remodeling complexes and uses thereof
AU2019416589B2 (en) *	2018-12-29	2023-04-06	Wuhan Ll Science And Technology Development Co., Ltd.	Heterocyclic compound intermediate, preparation method therefor and application thereof
WO2020160196A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2020160100A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
EP4096668A4 (en) *	2020-01-29	2024-02-28	Foghorn Therapeutics Inc.	COMPOUNDS AND USES THEREOF
BR112022015004A2 (pt)	2020-01-29	2022-09-20	Foghorn Therapeutics Inc	Composto, composição farmacêutica, métodos para diminuir a atividade de um complexo baf, induzir apoptose, reduzir o crescimento tumoral, suprimir a progressão e a colonização metastática do câncer e reduzir o nível e/ou a atividade de brg1 e/ou brm em um câncer e métodos de tratamento e de inibição de brm e brg1
US12383555B2 (en)	2020-05-20	2025-08-12	Foghorn Therapeutics Inc.	Methods of treating cancers
JP2024509268A (ja)	2021-03-09	2024-02-29	フォグホーンセラピューティクスインコーポレイテッド	結晶形、それらを含有する組成物、及びそれらの使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB991589A (en) *	1963-04-30	1965-05-12	Selvi & C Lab Bioterapico	Novel [1,2-ª‡]imidazopyridines and a process for the manufacture thereof
GB1076089A (en) *	1965-11-09	1967-07-19	Selvi & C Lab Bioterapico	New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

1984
- 1984-08-07 FR FR8412447A patent/FR2568880B1/fr not_active Expired
1985
- 1985-07-30 DE DE8585401554T patent/DE3567867D1/de not_active Expired
- 1985-07-30 EP EP85401554A patent/EP0172096B1/fr not_active Expired
- 1985-07-30 AT AT85401554T patent/ATE40365T1/de not_active IP Right Cessation
- 1985-08-06 NZ NZ213013A patent/NZ213013A/en unknown
- 1985-08-06 ES ES545928A patent/ES8604592A1/es not_active Expired
- 1985-08-06 PT PT80921A patent/PT80921B/pt not_active IP Right Cessation
- 1985-08-06 GR GR851928A patent/GR851928B/el unknown
- 1985-08-06 DK DK356885A patent/DK163923C/da not_active IP Right Cessation
- 1985-08-06 AU AU45809/85A patent/AU575190B2/en not_active Ceased
- 1985-08-06 HU HU852991A patent/HU193799B/hu not_active IP Right Cessation
- 1985-08-06 CA CA000488165A patent/CA1261830A/en not_active Expired
- 1985-08-06 FI FI853026A patent/FI80696C/fi not_active IP Right Cessation
- 1985-08-06 NO NO853100A patent/NO162189C/no unknown
- 1985-08-06 IL IL76020A patent/IL76020A/xx not_active IP Right Cessation
- 1985-08-06 MX MX206217A patent/MX160845A/es unknown
- 1985-08-06 KR KR1019850005660A patent/KR910004450B1/ko not_active Expired
- 1985-08-06 ZA ZA855939A patent/ZA855939B/xx unknown
- 1985-08-06 IE IE193785A patent/IE58347B1/en not_active IP Right Cessation
- 1985-08-06 AR AR85301203A patent/AR241185A1/es active
- 1985-08-06 JP JP60173977A patent/JPS6147485A/ja active Granted
1986
- 1986-02-07 US US06/826,966 patent/US4650796A/en not_active Expired - Lifetime
1991
- 1991-11-25 CZ CS913576A patent/CZ357691A3/cs unknown

Also Published As

Publication number	Publication date
DK163923C (da)	1992-09-14
CZ357691A3 (en)	1993-06-16
FR2568880B1 (fr)	1986-12-12
NO853100L (no)	1986-02-10
ZA855939B (en)	1986-03-26
FI80696C (fi)	1990-07-10
ES545928A0 (es)	1986-02-01
PT80921A (fr)	1985-09-01
ES8604592A1 (es)	1986-02-01
EP0172096A1 (fr)	1986-02-19
PT80921B (pt)	1987-12-30
DK356885D0 (da)	1985-08-06
DK163923B (da)	1992-04-21
HUT38637A (en)	1986-06-30
IE58347B1 (en)	1993-09-08
MX160845A (es)	1990-05-31
JPH0523267B2 (2)	1993-04-02
NO162189C (no)	1989-11-29
US4650796A (en)	1987-03-17
KR860001809A (ko)	1986-03-22
IL76020A0 (en)	1985-12-31
AU575190B2 (en)	1988-07-21
HU193799B (en)	1987-11-30
NZ213013A (en)	1988-05-30
DK356885A (da)	1986-02-08
IL76020A (en)	1989-01-31
EP0172096B1 (fr)	1989-01-25
JPS6147485A (ja)	1986-03-07
NO162189B (no)	1989-08-14
GR851928B (2)	1985-12-09
CA1261830A (en)	1989-09-26
FI853026A0 (fi)	1985-08-06
FI853026L (fi)	1986-02-08
FI80696B (fi)	1990-03-30
AU4580985A (en)	1986-02-13
IE851937L (en)	1986-02-07
DE3567867D1 (en)	1989-03-02
KR910004450B1 (ko)	1991-06-29
FR2568880A1 (fr)	1986-02-14
ATE40365T1 (de)	1989-02-15

Publication	Publication Date	Title
ES8702400A1 (es)	1987-01-01	Procedimiento para la obtencion de acidos 7-amino-1-ciclopropil-6,8-dihalogeno-1,4-dihidro-4-oxo-3-quinolincarboxilico
DK157543C (da)	1990-06-11	Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse
AR240794A2 (es)	1991-02-28	Derivados de 2-(2'-nitrobenzoil)-1,3-ciclohexanodiona composicion herbicida que los comprende y procedimiento para prepararlos.
ES2033423T3 (es)	1993-03-16	Procedimientos para preparar derivados de 2-fenilpurinona.
ATE116303T1 (de)	1995-01-15	Aryl-heteroaryl-karbinol-derivate mit analgetischer aktivität.
AR240916A2 (es)	1991-03-27	"un procedimiento para la preparacion de nuevos derivados de n(fenil)amino)carbonil) bencensulfonamida".
ES8606304A1 (es)	1986-04-16	Un procedimiento para preparar derivados de tiazina
FI884132A0 (fi)	1988-09-08	1-/ (2-pyrimidinyl) -aminoalkyl/-piperidiner, deras framstaellning och anvaendning i terapi.
DK71780A (da)	1980-08-21	Fremgangsmaade til fremstilling af difenylhydantoinderivater
DK138982A (da)	1982-09-28	Fremgangsmaade til fremstilling af bispidinderivater
ES8301220A1 (es)	1982-12-01	Procedimiento para la preparacion de derivados de imidazol
ES2028042T3 (es)	1992-07-01	Procedimiento para la obtencion de derivados de 1,8-naftiridina y fungidas que les contienen.
NO177995C (no)	1996-01-03	Analogifremgangsmåte for fremstilling av terapeutisk aktive 1,3-dioksanderivater
ATE57184T1 (de)	1990-10-15	Gamma-carboline.
ES493527A0 (es)	1981-07-01	Procedimiento para la obtencion de derivados de triazo- lil-alquenos de efecto fungicida
DK247888D0 (da)	1988-05-06	Aminosyrederivater af 4-benzyl-1-(2h)-phthalazinon
DK624586A (da)	1987-06-25	10beta-alkynyloestrenderivater og fremgangsmaade til fremstilling deraf
DK1582A (da)	1982-01-05	Substituerede thienotricycler fremgangsmaade til fremstilling deraf og anvendelse af saadanne forbindelser
ES8705421A1 (es)	1987-05-01	Un procedimiento para la preparacion de 4-amino-2-fenil-quinolinas
DE3672352D1 (de)	1990-08-09	Aminoacrylsaeure-derivate.
SE8700914D0 (sv)	1987-03-04	Anvendning av adenosinderivat
ES2038684T3 (es)	1993-08-01	Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion.
ES2059550T3 (es)	1994-11-16	Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica.
ES519005A0 (es)	1984-12-16	Procedimiento para preparar 3-(1h-tetrazol-5-il)-4 (3 h)-quinazolinonas.
DE3661833D1 (de)	1989-02-23	Steroidic aromatase inhibitors