ES8604592A1 - Un procedimiento para preparar derivados de acilaminometil- 3-imidazo(1,2-a)piridinas - Google Patents

Un procedimiento para preparar derivados de acilaminometil- 3-imidazo(1,2-a)piridinas

Info

Publication number: ES8604592A1
Authority: ES; Spain
Prior art keywords: alkyl; acylaminomethylimidazo; pyridines; preparation; substd
Prior art date: 1984-08-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES545928A

Other languages

English (en)

Spanish (es)

Other versions

ES545928A0 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Synthelabo SA

Original Assignee

Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-07

Filing date

1985-08-06

Publication date

1986-02-01

1985-08-06 Application filed by Synthelabo SA filed Critical Synthelabo SA

1986-02-01 Publication of ES8604592A1 publication Critical patent/ES8604592A1/es

1986-02-01 Publication of ES545928A0 publication Critical patent/ES545928A0/es

Status Expired legal-status Critical Current

Links

150000003222 pyridines Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
-1 propen-1-yl Chemical group 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
ZBZJXHCVGLJWFG-UHFFFAOYSA-N trichloromethyl(.) Chemical compound Cl[C](Cl)Cl ZBZJXHCVGLJWFG-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ES545928A 1984-08-07 1985-08-06 Un procedimiento para preparar derivados de acilaminometil- 3-imidazo(1,2-a)piridinas Expired ES8604592A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8412447A FR2568880B1 (fr)	1984-08-07	1984-08-07	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number	Publication Date
ES8604592A1 true ES8604592A1 (es)	1986-02-01
ES545928A0 ES545928A0 (es)	1986-02-01

Family

ID=9306856

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES545928A Expired ES8604592A1 (es)	1984-08-07	1985-08-06	Un procedimiento para preparar derivados de acilaminometil- 3-imidazo(1,2-a)piridinas

Country Status (23)

Country	Link
US (1)	US4650796A (2)
EP (1)	EP0172096B1 (2)
JP (1)	JPS6147485A (2)
KR (1)	KR910004450B1 (2)
AR (1)	AR241185A1 (2)
AT (1)	ATE40365T1 (2)
AU (1)	AU575190B2 (2)
CA (1)	CA1261830A (2)
CZ (1)	CZ357691A3 (2)
DE (1)	DE3567867D1 (2)
DK (1)	DK163923C (2)
ES (1)	ES8604592A1 (2)
FI (1)	FI80696C (2)
FR (1)	FR2568880B1 (2)
GR (1)	GR851928B (2)
HU (1)	HU193799B (2)
IE (1)	IE58347B1 (2)
IL (1)	IL76020A (2)
MX (1)	MX160845A (2)
NO (1)	NO162189C (2)
NZ (1)	NZ213013A (2)
PT (1)	PT80921B (2)
ZA (1)	ZA855939B (2)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2593818B1 (fr) *	1986-02-05	1988-04-29	Synthelabo	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
FR2593180B1 (fr) *	1986-01-22	1990-10-26	Synthelabo	Derives d'acylaminomethyl-1 imidazo (1,2-a)quinoleines, leur preparation et leur application en therapeutique
DE3769333D1 (de) *	1986-01-22	1991-05-23	Synthelabo	Acylaminomethylimidazo(1,2-a)pyrimidinderivate, ihre herstellung und therapeutische verwendung.
US4990506A (en) *	1986-02-05	1991-02-05	Synthelabo	3-(acylaminomethyl)imidazo[1,2-a]pyridine derivatives and their application in therapy
FR2606409B1 (fr) *	1986-11-07	1989-05-05	Synthelabo	Derives d'imidazopyridine, leur preparation et leur application en therapeutique
ES2026666T3 (es) *	1987-03-27	1992-05-01	Synthelabo	Procedimiento para preparar derivados de imidazopiridinas.
FR2615513B1 (fr) *	1987-05-21	1989-07-13	Synthelabo	Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2654933B1 (fr) *	1989-11-30	1994-06-10	Synthelabo	Utilisation d'une imidazopyridine pour la fabrication de medicaments anesthesiques.
US5716964A (en) *	1989-12-04	1998-02-10	G.D. Searle & Co.	Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
KR910011852A (ko) *	1989-12-04	1991-08-07	폴 디. 매튜카이티스	신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
IE904346A1 (en) *	1989-12-04	1991-06-05	Searle & Co	IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
US5464843A (en) *	1992-06-23	1995-11-07	G.D. Searle & Co.	Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AUPP278498A0 (en)	1998-04-03	1998-04-30	Australian Nuclear Science & Technology Organisation	Peripheral benzodiazepine receptor binding agents
DE10019714A1 (de) *	2000-04-20	2002-01-10	Gruenenthal Gmbh	Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
AU2001270297A1 (en)	2000-06-30	2002-01-14	Neurogen Corporation	2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
DE10247269A1 (de) *	2002-10-10	2004-04-22	Grünenthal GmbH	Substituierte C-Imidazo[1,2-a]pyridin-3-yl-methylamine
ATE482211T1 (de) *	2003-10-28	2010-10-15	Sepracor Inc	Imidazoä1,2-aüpyridin-anxiolytika
WO2005081749A2 (en) *	2004-01-23	2005-09-09	Avanir Pharmaceuticals, Inc.	Neutralizing human antibodies to anthraxtoxin
FR2874611B1 (fr) *	2004-08-31	2006-11-17	Servier Lab	Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1814880B1 (en) *	2004-11-11	2009-01-28	Ferrer Internacional, S.A.	Imidazo[1,2-a]pyridine compounds, compositions, uses and methods related thereto
AU2006254335A1 (en)	2005-06-01	2006-12-07	Ucb Pharma, S.A.	2-oxo-1-pyrrolidine derivatives and their therapeutic use on the central nervous system
EP2152262A2 (en) *	2007-04-27	2010-02-17	UCB Pharma, S.A.	New heterocyclic derivatives useful for the treatment of cns disorders
WO2009143156A2 (en) *	2008-05-19	2009-11-26	Sepracor Inc.	IMIDAZO[1,2-a]PYRIDINE COMPOUNDS
WO2010064020A1 (en) *	2008-12-04	2010-06-10	Proximagen Ltd.	Imidazopyridine compounds
US20160120863A1 (en)	2013-05-24	2016-05-05	Iomet Pharma Ltd.	Slc2a transporter inhibitors
WO2017087885A1 (en)	2015-11-19	2017-05-26	Dana-Farber Cancer Institute, Inc.	Methods of identifying compounds that interfere with erg-driven misguidance of baf complexes in tmprss2-erg driven prostate cancers
WO2019152437A1 (en)	2018-01-30	2019-08-08	Foghorn Therapeutics Inc.	Compounds and uses thereof
US12473334B2 (en)	2018-10-17	2025-11-18	Dana-Farber Cancer Institute, Inc.	SWI/SNF family chromatin remodeling complexes and uses thereof
AU2019416589B2 (en) *	2018-12-29	2023-04-06	Wuhan Ll Science And Technology Development Co., Ltd.	Heterocyclic compound intermediate, preparation method therefor and application thereof
WO2020160196A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2020160100A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2021155262A1 (en)	2020-01-29	2021-08-05	Foghorn Therapeutics Inc.	Compounds and uses thereof
US20230121497A1 (en) *	2020-01-29	2023-04-20	Foghorn Therapeutics Inc.	Compounds and uses thereof
US12383555B2 (en)	2020-05-20	2025-08-12	Foghorn Therapeutics Inc.	Methods of treating cancers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB991589A (en) *	1963-04-30	1965-05-12	Selvi & C Lab Bioterapico	Novel [1,2-ª‡]imidazopyridines and a process for the manufacture thereof
GB1076089A (en) *	1965-11-09	1967-07-19	Selvi & C Lab Bioterapico	New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

1984
- 1984-08-07 FR FR8412447A patent/FR2568880B1/fr not_active Expired
1985
- 1985-07-30 AT AT85401554T patent/ATE40365T1/de not_active IP Right Cessation
- 1985-07-30 EP EP85401554A patent/EP0172096B1/fr not_active Expired
- 1985-07-30 DE DE8585401554T patent/DE3567867D1/de not_active Expired
- 1985-08-06 FI FI853026A patent/FI80696C/fi not_active IP Right Cessation
- 1985-08-06 HU HU852991A patent/HU193799B/hu not_active IP Right Cessation
- 1985-08-06 IE IE193785A patent/IE58347B1/en not_active IP Right Cessation
- 1985-08-06 AR AR85301203A patent/AR241185A1/es active
- 1985-08-06 PT PT80921A patent/PT80921B/pt not_active IP Right Cessation
- 1985-08-06 ES ES545928A patent/ES8604592A1/es not_active Expired
- 1985-08-06 KR KR1019850005660A patent/KR910004450B1/ko not_active Expired
- 1985-08-06 CA CA000488165A patent/CA1261830A/en not_active Expired
- 1985-08-06 AU AU45809/85A patent/AU575190B2/en not_active Ceased
- 1985-08-06 NO NO853100A patent/NO162189C/no unknown
- 1985-08-06 NZ NZ213013A patent/NZ213013A/en unknown
- 1985-08-06 DK DK356885A patent/DK163923C/da not_active IP Right Cessation
- 1985-08-06 GR GR851928A patent/GR851928B/el unknown
- 1985-08-06 JP JP60173977A patent/JPS6147485A/ja active Granted
- 1985-08-06 IL IL76020A patent/IL76020A/xx not_active IP Right Cessation
- 1985-08-06 ZA ZA855939A patent/ZA855939B/xx unknown
- 1985-08-06 MX MX206217A patent/MX160845A/es unknown
1986
- 1986-02-07 US US06/826,966 patent/US4650796A/en not_active Expired - Lifetime
1991
- 1991-11-25 CZ CS913576A patent/CZ357691A3/cs unknown

Also Published As

Publication number	Publication date
ZA855939B (en)	1986-03-26
FR2568880A1 (fr)	1986-02-14
DK356885A (da)	1986-02-08
JPS6147485A (ja)	1986-03-07
FI80696C (fi)	1990-07-10
EP0172096A1 (fr)	1986-02-19
IE851937L (en)	1986-02-07
CZ357691A3 (en)	1993-06-16
NO162189B (no)	1989-08-14
DE3567867D1 (en)	1989-03-02
AU575190B2 (en)	1988-07-21
GR851928B (2)	1985-12-09
MX160845A (es)	1990-05-31
DK356885D0 (da)	1985-08-06
IL76020A0 (en)	1985-12-31
PT80921B (pt)	1987-12-30
KR860001809A (ko)	1986-03-22
FR2568880B1 (fr)	1986-12-12
ES545928A0 (es)	1986-02-01
EP0172096B1 (fr)	1989-01-25
JPH0523267B2 (2)	1993-04-02
HU193799B (en)	1987-11-30
IE58347B1 (en)	1993-09-08
US4650796A (en)	1987-03-17
AU4580985A (en)	1986-02-13
PT80921A (fr)	1985-09-01
AR241185A1 (es)	1992-01-31
NO853100L (no)	1986-02-10
ATE40365T1 (de)	1989-02-15
HUT38637A (en)	1986-06-30
DK163923B (da)	1992-04-21
NO162189C (no)	1989-11-29
DK163923C (da)	1992-09-14
FI853026L (fi)	1986-02-08
NZ213013A (en)	1988-05-30
FI853026A0 (fi)	1985-08-06
KR910004450B1 (ko)	1991-06-29
IL76020A (en)	1989-01-31
CA1261830A (en)	1989-09-26
FI80696B (fi)	1990-03-30

Legal Events

Date	Code	Title	Description
2006-11-01	FD1A	Patent lapsed	Effective date: 20041127

Publication	Publication Date	Title
ES8604592A1 (es)	1986-02-01	Un procedimiento para preparar derivados de acilaminometil- 3-imidazo(1,2-a)piridinas
EP0321846A3 (en)	1990-03-28	Pyrimidine derivatives, processes for their production, and herbicidal method and compositions
AU7874187A (en)	1988-03-24	4-aminoquinoline derivatives
IL73608A (en)	1987-12-31	Pyridine-2-(thio)ether derivatives having a nitrogen containing ring,their preparation and pharmaceutical compositions containing them
IL80033A (en)	1992-05-25	1-substituted 7-bridged-diazabicyclo-alkyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids,related compounds and antibacterial pharmaceutical compositions containing them
EP0223385A3 (en)	1988-12-21	8-azabicycloû3,2,1¨octane and 9-azabicycloû3,3,1¨nonane derivatives
NZ229861A (en)	1989-10-27	2,5,6-trisubstituted pyridine-3-carboxylic acids and acid derivatives
DE3471934D1 (en)	1988-07-14	7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments
EP0288275A3 (en)	1989-01-11	Novel phenoxypropionic acid derivatives for use as herbicides
ES8801280A1 (es)	1988-01-01	Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas
AU573899B2 (en)	1988-06-23	Pyrazolo(3,4-b)-pyridine amided
EP0222283A3 (en)	1989-09-06	Amino-acid derivatives
ES8407477A1 (es)	1984-10-01	Procedimiento de preparar nuevos derivados de sales inertes de hidroxido de aminopiridinio y sus sales correspondientes
DE3568045D1 (en)	1989-03-09	Furoû3,2-c¨pyridine derivatives, their preparation and their therapeutical use
PT80221B (en)	1987-02-17	Improved process for preparing benzamide derivatives useful as anticonvulsant agents
ZA845931B (en)	1985-06-26	1-(4'-alkylsulphonylphenyl)-2-amino-1,3-propanediol n-substituted derivatives
ES8603416A1 (es)	1985-12-16	Un procedimiento para preparar derivados de dihidropiridina
IL81051A0 (en)	1987-03-31	6h-isoxazolo(5,4-d)pyrazol(3,4-b)pyridines,a process and intermediates for their preparation and pharmaceutical compositions containing them
ES8801295A1 (es)	1987-12-16	Un procedimiento para preparar derivados de fosfina
PL338009A1 (en)	2000-09-25	2,4,4-three-substituted 1,3-dioxolane based antimycotic agents
ATE88176T1 (de)	1993-04-15	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
MY110277A (en)	1998-03-31	Acylsulfonamido-and sulfonamidopyridine-2-carboxylic acid esters and their pyridine n-oxides, processes for their preparation and their use as medicaments
ES8604583A1 (es)	1986-02-01	Procedimiento para preparar derivados de 4,5,6,7-tetrahidro-furo- 0 1h-pirrolo-(2,3-c)piridina
ES8603175A1 (es)	1985-12-16	Procedimiento para preparar derivados de benzotiazol
GR3004095T3 (2)	1993-03-31