AT335428B - PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN - Google Patents

PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN

Info

Publication number
AT335428B
AT335428B AT310175A AT310175A AT335428B AT 335428 B AT335428 B AT 335428B AT 310175 A AT310175 A AT 310175A AT 310175 A AT310175 A AT 310175A AT 335428 B AT335428 B AT 335428B
Authority
AT
Austria
Prior art keywords
biphenylyl
sep
olen
buten
butanols
Prior art date
Application number
AT310175A
Other languages
German (de)
Other versions
ATA310175A (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2330838A external-priority patent/DE2330838A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Priority to AT310175A priority Critical patent/AT335428B/en
Publication of ATA310175A publication Critical patent/ATA310175A/en
Application granted granted Critical
Publication of AT335428B publication Critical patent/AT335428B/en

Links

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Description

  

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<tb> 
<tb> betrifftSubstanz <SEP> Kaolinödem <SEP> Carrageenin- <SEP> Mittelwert <SEP> aknte <SEP> Toxizität <SEP> Ratte <SEP> Therapeutischer <SEP> Index <SEP> 
<tb> ED35 <SEP> per <SEP> os <SEP> ödem <SEP> ED35 <SEP> mg/kg
<tb> mg/kg <SEP> ED35 <SEP> per <SEP> os <SEP> LD50 <SEP> mg/kg <SEP> Verhältnis <SEP> zwischen
<tb> mg/kg <SEP> toxischer <SEP> und <SEP> antiexsudativer <SEP> Wirkung
<tb> LD50/ED35
<tb> Phenylbutazon <SEP> 58 <SEP> 69 <SEP> 63,

   <SEP> 5 <SEP> 864 <SEP> (793 <SEP> - <SEP> 942) <SEP> 13, <SEP> 6
<tb> A <SEP> 11, <SEP> 5 <SEP> 13, <SEP> 0 <SEP> 12, <SEP> 3 <SEP> 910 <SEP> (664 <SEP> - <SEP> 1247) <SEP> 74, <SEP> 0
<tb> B <SEP> 22, <SEP> 5 <SEP> 9, <SEP> 6 <SEP> 16, <SEP> 1 <SEP> 720 <SEP> (550 <SEP> - <SEP> 943) <SEP> 44, <SEP> 7
<tb> C <SEP> 15, <SEP> 5 <SEP> 12, <SEP> 5 <SEP> 14 <SEP> > 4000 <SEP> (1/10) <SEP> > 286
<tb> D <SEP> 12, <SEP> 0 <SEP> 8, <SEP> 7 <SEP> 10, <SEP> 4 <SEP> 825 <SEP> (665 <SEP> - <SEP> 1023) <SEP> 79,3
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<tb>
<tb> concerns substance <SEP> kaolin edema <SEP> carrageenin <SEP> mean value <SEP> acne <SEP> toxicity <SEP> rat <SEP> therapeutic <SEP> index <SEP>
<tb> ED35 <SEP> per <SEP> os <SEP> edema <SEP> ED35 <SEP> mg / kg
<tb> mg / kg <SEP> ED35 <SEP> per <SEP> os <SEP> LD50 <SEP> mg / kg <SEP> ratio <SEP> between
<tb> mg / kg <SEP> toxic <SEP> and <SEP> antiexudative <SEP> effect
<tb> LD50 / ED35
<tb> Phenylbutazon <SEP> 58 <SEP> 69 <SEP> 63,

   <SEP> 5 <SEP> 864 <SEP> (793 <SEP> - <SEP> 942) <SEP> 13, <SEP> 6
<tb> A <SEP> 11, <SEP> 5 <SEP> 13, <SEP> 0 <SEP> 12, <SEP> 3 <SEP> 910 <SEP> (664 <SEP> - <SEP> 1247) < SEP> 74, <SEP> 0
<tb> B <SEP> 22, <SEP> 5 <SEP> 9, <SEP> 6 <SEP> 16, <SEP> 1 <SEP> 720 <SEP> (550 <SEP> - <SEP> 943) < SEP> 44, <SEP> 7
<tb> C <SEP> 15, <SEP> 5 <SEP> 12, <SEP> 5 <SEP> 14 <SEP>> 4000 <SEP> (1/10) <SEP>> 286
<tb> D <SEP> 12, <SEP> 0 <SEP> 8, <SEP> 7 <SEP> 10, <SEP> 4 <SEP> 825 <SEP> (665 <SEP> - <SEP> 1023) < SEP> 79.3
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Claims (1)

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AT310175A 1973-06-16 1975-04-23 PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN AT335428B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT310175A AT335428B (en) 1973-06-16 1975-04-23 PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2330838A DE2330838A1 (en) 1973-06-16 1973-06-16 NEW CARBONIC ACID ESTERS OF 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) 2-BUTEN-1-OLEN
AT485374A AT329037B (en) 1973-06-16 1974-06-12 PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN
AT310175A AT335428B (en) 1973-06-16 1975-04-23 PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN

Publications (2)

Publication Number Publication Date
ATA310175A ATA310175A (en) 1976-07-15
AT335428B true AT335428B (en) 1977-03-10

Family

ID=27149167

Family Applications (1)

Application Number Title Priority Date Filing Date
AT310175A AT335428B (en) 1973-06-16 1975-04-23 PROCESS FOR THE PREPARATION OF NEW CARBON ACID ESTERS FROM 3- (4-BIPHENYLYL) -1-BUTANOLS AND 3- (4-BIPHENYLYL) -2-BUTEN-1-OLEN

Country Status (1)

Country Link
AT (1) AT335428B (en)

Also Published As

Publication number Publication date
ATA310175A (en) 1976-07-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee