AT390254B - Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen - Google Patents

Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen Download PDF

Info

Publication number
AT390254B
AT390254B AT0388782A AT388782A AT390254B AT 390254 B AT390254 B AT 390254B AT 0388782 A AT0388782 A AT 0388782A AT 388782 A AT388782 A AT 388782A AT 390254 B AT390254 B AT 390254B
Authority
AT
Austria
Prior art keywords
group
compound
general formula
alkyl group
acid
Prior art date
Application number
AT0388782A
Other languages
German (de)
English (en)
Other versions
ATA388782A (de
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ATA388782A publication Critical patent/ATA388782A/de
Application granted granted Critical
Publication of AT390254B publication Critical patent/AT390254B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0388782A 1981-10-22 1982-10-22 Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen AT390254B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49549/81A IT1171605B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
ATA388782A ATA388782A (de) 1989-09-15
AT390254B true AT390254B (de) 1990-04-10

Family

ID=11270996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0388782A AT390254B (de) 1981-10-22 1982-10-22 Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen

Country Status (13)

Country Link
US (1) US4486429A (fr)
JP (1) JPS5883664A (fr)
AT (1) AT390254B (fr)
BE (1) BE894767A (fr)
CA (1) CA1189526A (fr)
CH (1) CH655715A5 (fr)
DE (1) DE3239209A1 (fr)
FR (1) FR2534909B1 (fr)
GB (1) GB2108500B (fr)
IT (1) IT1171605B (fr)
LU (1) LU84430A1 (fr)
NL (1) NL8204060A (fr)
SE (1) SE456502B (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2112716A1 (de) * 1971-03-17 1972-10-05 Thomae Gmbh Dr K Neue 4-(4-Biphenylyl)-4-oxobuttersaeuren,ihre Salze und ihre Ester

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
US2555955A (en) * 1948-03-25 1951-06-05 Searle & Co Phenyl amino benzoyl alkanoic acids
US3046301A (en) * 1959-10-29 1962-07-24 Burroughs Wellcome Co Method of making chlorambucil
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
GR37790B (el) * 1966-12-30 1969-07-15 F. Hoffmann - La Roche & Co. Aktiengesellschaft Μεθοδος δια την παρασκευην παραγωγων του αρουλακρυλικου οξεος.
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
DE2123246C2 (de) * 1971-05-11 1982-11-25 Basf Ag, 6700 Ludwigshafen 6-[p-(β-Phenyläthylaminoacetylamino)-phenyl]-4,5-dihydropyridazon-(3)
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
CH591415A5 (en) * 1972-09-13 1977-09-15 Takeda Chemical Industries Ltd 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
FR2270856B1 (fr) * 1974-01-17 1978-07-21 Screen
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
IL48319A0 (en) * 1974-10-26 1975-12-31 Merck Patent Gmbh Araliphatic nitrogen compounds and a process for their preparation
JPS5536434A (en) * 1978-09-07 1980-03-14 Sankyo Co Ltd 4-phenyl-4-oxo-2-butenoic acid derivative and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2112716A1 (de) * 1971-03-17 1972-10-05 Thomae Gmbh Dr K Neue 4-(4-Biphenylyl)-4-oxobuttersaeuren,ihre Salze und ihre Ester

Also Published As

Publication number Publication date
DE3239209A1 (de) 1983-05-05
FR2534909A1 (fr) 1984-04-27
CH655715A5 (fr) 1986-05-15
JPS5883664A (ja) 1983-05-19
ATA388782A (de) 1989-09-15
LU84430A1 (fr) 1983-06-13
CA1189526A (fr) 1985-06-25
BE894767A (fr) 1983-04-21
IT1171605B (it) 1987-06-10
SE8205869L (sv) 1983-04-23
SE456502B (sv) 1988-10-10
GB2108500B (en) 1985-05-15
NL8204060A (nl) 1983-05-16
IT8149549A1 (it) 1983-04-22
GB2108500A (en) 1983-05-18
US4486429A (en) 1984-12-04
SE8205869D0 (sv) 1982-10-15
FR2534909B1 (fr) 1986-02-14
IT8149549A0 (it) 1981-10-22

Similar Documents

Publication Publication Date Title
DE2938302A1 (de) Neue derivate des 3-(aminoaethyl)- phenols und deren salze, deren herstellungsverfahren, deren verwendung als arzneimittel und die diese enthaltenden pharmazeutischen zusammensetzungen
AT391689B (de) Verfahren zur herstellung von neuen 4-phenyl-4-oxo-2-butensaeurederivaten und von deren salzen
DE69313640T2 (de) Zink-tranexamat derivat
EP0006114B1 (fr) Acide 7-méthoxy-5-oxo-5H-thiazolo(2,3-b)quinazoline-2-carboxylique et ses sels pharmaceutiquement acceptables, leur procédé de préparation et médicaments les contenant
DE2044172C3 (de) Pyrrolderivate, ein Verfahren zu ihrer Herstellung und Arzneimittel
DE3804936C2 (de) Piperazincarbonsäure, ihre Herstellung und diese enthaltende Arzneimittel
DE1932389B2 (de) Neue 2-Naphthyl-2-methyläthanole und deren Acetate, sie enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
AT390254B (de) Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen
DE2336670A1 (de) Aminoaether von o-thymotinsaeureestern
DE3239189A1 (de) Zur verwendung als arzneimittel bestimmte derivate der 4-phenyl-4-oxo-2-butensaeure und diese enthaltende zusammensetzungen
DE69509091T2 (de) Salze von 2-[(2,6-dichlorophenyl)amin]phenylacetoxyessigsäure mit organischen basischen kationen
DE2238280A1 (de) Furanderivate enthaltende arzneimittel und neue n-furoylmorpholinverbindungen
DE2336671A1 (de) Oxyessigsaeureaether von o-thymotinsaeureestern
DE2736268A1 (de) Neue 5-thiazolalkylamin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE2618936C3 (de) N-Acyl-glutamine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DD283375A5 (de) Verwendung des tromethamin-salzes von 1-methyl-beta-oxo-alpha-(phenylcarbamoyl);2-pyrrol-propionitril
DE2530515C2 (de) 4- bzw. 7-Hydroxy-4,5,6,7-tetrahydrothieno-[3,2-c] bzw.[2,3-c] pyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittelzubereitungen
DE2931319A1 (de) 6-methoxy-2-acetylnaphthalinoxim- derivate, verfahren zu ihrer herstellung sowie sie enthaltende arzneimittel
DE69608983T2 (de) Thiophenverbindungen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
CH516593A (de) Verfahren zur Herstellung von neuen Estern von a-Aminobenzyl-penicillin
DE3239220C2 (fr)
DE69012213T2 (de) Phenylessigsäurederivat.
DE3214081A1 (de) Verwendung von phenyl-aliphatischen carbonsaeurederivaten als arzneimittel
EP0137499A2 (fr) Procédé de production d'acide bêta-élémonique, et préparations pharmaceutiques les contenant
DE2024045A1 (de) Derivate von Dibenzo(a,d)-5Hcyclohepten

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time