ATA216984A - Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen - Google Patents

Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Info

Publication number
ATA216984A
ATA216984A AT0216984A AT216984A ATA216984A AT A216984 A ATA216984 A AT A216984A AT 0216984 A AT0216984 A AT 0216984A AT 216984 A AT216984 A AT 216984A AT A216984 A ATA216984 A AT A216984A
Authority
AT
Austria
Prior art keywords
lactam
beta
salts
amino
sulphonic acids
Prior art date
Application number
AT0216984A
Other languages
English (en)
Other versions
AT380472B (de
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0055081A external-priority patent/AT378367B/de
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Priority to AT0216984A priority Critical patent/AT380472B/de
Publication of ATA216984A publication Critical patent/ATA216984A/de
Application granted granted Critical
Publication of AT380472B publication Critical patent/AT380472B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0216984A 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen AT380472B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0216984A AT380472B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18889380A 1980-09-29 1980-09-29
AT0055081A AT378367B (de) 1981-02-06 1981-02-06 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen
AT0216984A AT380472B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Publications (2)

Publication Number Publication Date
ATA216984A true ATA216984A (de) 1985-10-15
AT380472B AT380472B (de) 1986-05-26

Family

ID=26884568

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0216884A AT381089B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen
AT0216984A AT380472B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0216884A AT381089B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Country Status (2)

Country Link
US (1) US4775670A (de)
AT (2) AT381089B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113072475A (zh) * 2021-03-30 2021-07-06 山东金城医药化工有限公司 氨曲南中间体的合成方法

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US5077432A (en) * 1990-01-22 1991-12-31 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
US5194604A (en) * 1990-06-29 1993-03-16 E. R. Squibb & Sons, Inc. Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains
ZA918014B (en) * 1990-11-05 1992-07-29 Squibb & Sons Inc Heteroaroyl derivatives of monocyclic beta-lactam antibiotics
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DE69232825D1 (de) * 1991-08-14 2002-11-21 Procter & Gamble Pharma Zyklische Harnstoffe mit antiarrhythmischer und antifibrillatorischer Wirkung
WO1993004064A1 (en) * 1991-08-14 1993-03-04 Procter & Gamble Pharmaceuticals, Inc. Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
US5888998A (en) * 1997-04-24 1999-03-30 Synphar Laboratories, Inc. 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors
US5994340A (en) * 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors
US6335324B1 (en) 1998-06-25 2002-01-01 Bristol-Myers Squibb Co. Beta lactam compounds and their use as inhibitors of tryptase
US6498170B2 (en) * 2000-07-17 2002-12-24 Wyeth Cyclamine sulfonamides as β-3 adrenergic receptor agonists
US7214364B2 (en) * 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
DE122011100043I1 (de) 2000-12-27 2011-12-15 Gilead Sciences Inc Inhalierbares aztreonam zur behandlung und vorbeugung von bakteriellen lungeninfektionen.
AU2002322247A1 (en) * 2001-08-03 2003-02-17 Chirologix Pharmaceutical Inc. Antibacterial oxazinones and methods for their use and synthesis
US20030232820A1 (en) * 2001-08-29 2003-12-18 Saul Wolfe Method for synthesizing oxazinones
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WO2004103999A1 (en) * 2003-05-15 2004-12-02 TEVA Gyógyszergyár Részvénytársaság AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT
AU2004256124B2 (en) * 2003-07-02 2011-04-28 Corus Pharma, Inc. Aztreonam L-lysine and methods for the preparation thereof
US20050005101A1 (en) * 2003-07-03 2005-01-06 Yenduri Bhargava K. Kernel cryptographic module signature verification system and method
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CN100486964C (zh) * 2006-12-15 2009-05-13 北京赛科药业有限责任公司 一种合成（2s-反式）-3-氨基-2-甲基-4-氧代-1-氮杂环丁基磺酸的方法
CN100469777C (zh) * 2006-12-15 2009-03-18 北京赛科药业有限责任公司 氨曲南的制备方法
CN102584811A (zh) * 2011-12-29 2012-07-18 蚌埠丰原涂山制药有限公司 一种氨曲南的制备方法
CN102807519A (zh) * 2012-08-14 2012-12-05 济南瑞丰医药科技有限公司 一种氨曲南侧链小环的制备方法
MX373444B (es) 2014-03-24 2020-04-30 Novartis Ag Compuestos organicos de monobactam para el tratamiento de infecciones bacterianas.
PL3353175T3 (pl) 2015-09-23 2021-02-22 Novartis Ag Sole i postacie stałe antybiotyku monobaktamowego
CN105481731A (zh) * 2015-12-21 2016-04-13 山东金城医药化工股份有限公司 N-磺基-n-苄氧羰基-o-甲烷磺酸基-l-苏氨酸酰胺钠盐的制备方法
CN108341764B (zh) * 2017-01-25 2021-02-09 重庆常捷医药有限公司 一种氨曲南母核的合成方法
JP7235718B2 (ja) 2017-08-02 2023-03-08 ノバルティス アーゲー モノバクタム系抗生物質およびその中間体を製造するための化学的方法
KR102455390B1 (ko) * 2017-10-02 2022-10-17 아릭사 파마슈티컬스 인코포레이티드 아즈트레오남 유도체 및 이의 용도
US11565999B2 (en) 2019-04-25 2023-01-31 Arixa Pharmaceuticals, Inc. Methods of synthesizing aztreonam derivatives
CN112279783B (zh) * 2020-09-27 2022-09-02 山东新和成精化科技有限公司 一种超临界条件下制备3-羟基丙腈的方法
JP2024532211A (ja) * 2021-08-20 2024-09-05 ユニバーシティ・オブ・ノートル・ダム・デュ・ラック 単環式β－ラクタムとシデロフォア模倣体との結合体

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Publication number Priority date Publication date Assignee Title
CN113072475A (zh) * 2021-03-30 2021-07-06 山东金城医药化工有限公司 氨曲南中间体的合成方法

Also Published As

Publication number Publication date
US4775670A (en) 1988-10-04
AT380472B (de) 1986-05-26
AT381089B (de) 1986-08-25
ATA216884A (de) 1986-01-15

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