ATA242786A - Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats - Google Patents

Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Info

Publication number
ATA242786A
ATA242786A AT0242786A AT242786A ATA242786A AT A242786 A ATA242786 A AT A242786A AT 0242786 A AT0242786 A AT 0242786A AT 242786 A AT242786 A AT 242786A AT A242786 A ATA242786 A AT A242786A
Authority
AT
Austria
Prior art keywords
carboxylats
pyridiniummethyl
cephem
methylethoxy
acetamido
Prior art date
Application number
AT0242786A
Other languages
English (en)
Other versions
AT387779B (de
Inventor
W Dr Veit
K Dr Wessely
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0242786A priority Critical patent/AT387779B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Priority to AT87905949T priority patent/ATE74922T1/de
Priority to EP87905949A priority patent/EP0282531B1/de
Priority to DE8787905949T priority patent/DE3778346D1/de
Priority to KR1019880700504A priority patent/KR950010085B1/ko
Priority to PCT/EP1987/000510 priority patent/WO1988002001A1/de
Priority to JP62505355A priority patent/JP2539872B2/ja
Publication of ATA242786A publication Critical patent/ATA242786A/de
Application granted granted Critical
Publication of AT387779B publication Critical patent/AT387779B/de
Priority to US07/494,272 priority patent/US5182383A/en
Priority to HK78195A priority patent/HK78195A/xx
Priority to JP8005639A priority patent/JP2572563B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT0242786A 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats AT387779B (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats
EP87905949A EP0282531B1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporin-zwischenproduktes
DE8787905949T DE3778346D1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporin-zwischenproduktes.
KR1019880700504A KR950010085B1 (ko) 1986-09-10 1987-09-09 안정한 결정형태의 세팔로스포린 중간생성물
AT87905949T ATE74922T1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporinzwischenproduktes.
PCT/EP1987/000510 WO1988002001A1 (fr) 1986-09-10 1987-09-09 Nouvelle forme cristalline stable d'un produit intermediaire de la cephalosporine
JP62505355A JP2539872B2 (ja) 1986-09-10 1987-09-09 セファロスポリン中間生成物の新規安定な結晶形
US07/494,272 US5182383A (en) 1986-09-10 1990-02-23 Stable, crystalline form of a cephalosporin intermediate product
HK78195A HK78195A (en) 1986-09-10 1995-05-18 Stable crystalline form of an intermediate product of cephalosporine
JP8005639A JP2572563B2 (ja) 1986-09-10 1996-01-17 セファロスポリン中間生成物の新規安定な結晶形

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Publications (2)

Publication Number Publication Date
ATA242786A true ATA242786A (de) 1988-08-15
AT387779B AT387779B (de) 1989-03-10

Family

ID=3534157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Country Status (1)

Country Link
AT (1) AT387779B (de)

Also Published As

Publication number Publication date
AT387779B (de) 1989-03-10

Similar Documents

Publication Publication Date Title
ATA276783A (de) Verfahren zur herstellung einer amorphen form des (6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl -2-methoxyiminoacetamido)-ceph-3-em-4-carbonsaeu e-1 acetoxyethylesters
ATA57097A (de) Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung
ES495534A0 (es) Un procedimiento para la preparacion de (6r,7r)-7-((z)-2- (2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetami- do)-3-(1-piridiniometil)cef-3-em-4-carboxilato pentahidrata-do
AR229883A1 (es) Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
DE68909176D1 (de) Verfahren zur Herstellung nahtloser Rohre aus Titan.
DE3888003D1 (de) Verfahren zur Herstellung keramischer Supraleiter.
AT383351B (de) Verfahren zur herstellung der neuen 7beta-(d-2amino-(p-hydroxyphenyl)-acetamido)-3-((z)-1propen-1-yl)-3-cephem-4-carbonsaeure
ATA202886A (de) Verfahren zur herstellung eines kristallinen dimethylformamidsolvats der 7-((d)-2-amino2-(4-hydroxyphenyl)-acetamido)-3-((z)-1propenyl)-ceph-3-em-4-carbons|ure
ATA242886A (de) Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r, 7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2(1-tert.butoxycarbonyl-1-methylethoxy)imino)
ES544410A0 (es) Un procedimiento para la preparacion de dihidrobromuro de acido (6r,7r)-7-((z)-2-(2-tritilaminotiazol-4-il)-2-(2-t-butiloxicarbonil-prop-2-oximino)acetamido)-3-(1piridiniometil)-3-cefem-4-carboxilico cristalino.
ATE17578T1 (de) Verfahren zur herstellung von furanderivaten.
DE60142329D1 (de) Ein verfahren zur herstellung von cephalosporin-derivaten unter verwendung von thiazolverbindungen
FI913951A7 (fi) Menetelmä kiteisen 7- -amino-3-(5-karboksimetyyli-4-metyyli-1,3-tiatsol-2-yyli-tiometyyli)-kef-3-emi-4-karboksyylihapon (TACS) valmistamiseksi
AT387022B (de) Verfahren zur herstellung einer neuen kristallinen form eines cefalosporinderivats
IT8221939A0 (it) Immidazolil-propionitrili, procedimento per la preparazione di questi composti nonche' mezzi biocidi che li contengono.
IL68931A0 (en) Novel process for producing 2-(2-aminothiazol-4-yl)glyoxylic acid derivative or a salt thereof,and intermediates therefor and process for producing the intermediates
ATE11536T1 (de) Verfahren zur herstellung eines furanderivats.
ES531532A0 (es) Un procedimiento para la preparacion de nuevas cefalosporinas.
AT380881B (de) Verfahren zur herstellung des neuen 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-(theophyllin-7-yl)-1-propansulfonats
EP0122584A3 (de) Neue Kristallmodifikation von Ceftazidim
ATE31532T1 (de) Thiazolderivat, verfahren zu seiner herstellung sowie seine verwendung bei der herstellung von beta-lactam-antibiotika.
FI812782A7 (fi) Menetelmä bis-tetratsoyylimetyyli- substituoitujen kefalosporiini-antibioottien valmistamiseksi.
EP0185220A3 (de) Zwischenprodukte zur Herstellung von Cephalosporinen
DK391883A (da) Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e)
ES508833A0 (es) Procedimientos para preparar derivados de acido cefaloesporanico.