ATA288275A - Verfahren zur herstellung neuer pyridinderivate und ihrer n-oxide und salze - Google Patents

Verfahren zur herstellung neuer pyridinderivate und ihrer n-oxide und salze

Info

Publication number
ATA288275A
ATA288275A AT288275A AT288275A ATA288275A AT A288275 A ATA288275 A AT A288275A AT 288275 A AT288275 A AT 288275A AT 288275 A AT288275 A AT 288275A AT A288275 A ATA288275 A AT A288275A
Authority
AT
Austria
Prior art keywords
oxides
salts
preparation
pyridine derivatives
new pyridine
Prior art date
Application number
AT288275A
Other languages
English (en)
Other versions
AT344170B (de
Original Assignee
Christiaens Sa A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christiaens Sa A filed Critical Christiaens Sa A
Priority to AT189877A priority Critical patent/AT345832B/de
Priority to AT189977A priority patent/AT344175B/de
Priority to AT189777A priority patent/AT344174B/de
Publication of ATA288275A publication Critical patent/ATA288275A/de
Application granted granted Critical
Publication of AT344170B publication Critical patent/AT344170B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT288275A 1974-04-17 1975-04-16 Verfahren zur herstellung neuer pyridinderivate und ihrer n-oxide und salze AT344170B (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT189877A AT345832B (de) 1974-04-17 1975-04-16 Verfahren zur herstellung neuer pyridinderivate und ihrer salze
AT189977A AT344175B (de) 1974-04-17 1977-03-18 Verfahren zur herstellung neuer pyridinderivate und ihrer salze
AT189777A AT344174B (de) 1974-04-17 1977-03-18 Verfahren zur herstellung neuer pyridinderivate und ihrer salze

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1683674A GB1477664A (en) 1974-04-17 1974-04-17 Pyridine derivatives
YU1507/81A YU42409B (en) 1974-04-17 1981-06-15 Process for obtaining new pyridine derivatives

Publications (2)

Publication Number Publication Date
ATA288275A true ATA288275A (de) 1977-11-15
AT344170B AT344170B (de) 1978-07-10

Family

ID=26252269

Family Applications (1)

Application Number Title Priority Date Filing Date
AT288275A AT344170B (de) 1974-04-17 1975-04-16 Verfahren zur herstellung neuer pyridinderivate und ihrer n-oxide und salze

Country Status (19)

Country Link
US (2) US4018929A (de)
JP (1) JPS5951536B2 (de)
AR (4) AR211097A1 (de)
AT (1) AT344170B (de)
BE (1) BE827844A (de)
CA (1) CA1070313A (de)
CH (3) CH612424A5 (de)
DD (2) DD126887A5 (de)
DE (1) DE2516025A1 (de)
ES (4) ES436581A1 (de)
FR (1) FR2267775B1 (de)
GB (1) GB1477664A (de)
HU (1) HU171420B (de)
IL (1) IL47084A (de)
LU (2) LU72284A1 (de)
NL (2) NL183580C (de)
SE (2) SE424320B (de)
YU (1) YU42409B (de)
ZA (1) ZA752243B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
US4776878A (en) * 1978-12-04 1988-10-11 E. I. Du Pont De Nemours And Company Agricultural pyridinesulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
US4853389A (en) * 1987-07-24 1989-08-01 American Home Products Corporation Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
US4914203A (en) * 1987-07-24 1990-04-03 American Home Products Corporation 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
FR2659080B1 (fr) * 1990-03-02 1994-07-08 Adir Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5486530A (en) * 1991-04-27 1996-01-23 Boehringer Mannheim Gmbh Use of torasemide for the treatment of brain oedemas
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
HRP980532B1 (en) * 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) * 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
JP2003527319A (ja) * 1999-08-11 2003-09-16 テバ ファーマシューティカル インダストリーズ リミティド トルセミド多形体
DE60103276T2 (de) 2000-02-17 2005-06-23 Teva Pharmaceutical Industries Ltd. Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält
EP1741429A3 (de) * 2000-03-20 2007-01-17 Teva Pharmaceutical Industries Ltd. Verfahren zur Herstellung von Torsemide
SK14802002A3 (sk) * 2000-03-20 2003-05-02 Teva Pharmaceutical Industries Ltd. Nový spôsob prípravy medziproduktu torsemidu
HRP20000162B1 (en) 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (de) 2001-08-03 2004-03-06 Ranbaxy Lab
IL149771A0 (en) * 2002-05-21 2002-11-10 Fintech Lab Ltd Process for preparation of torsemide
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
EP1545519B1 (de) 2002-08-19 2011-03-23 Pfizer Inc. Kombinationstherapie gegen hyperproliferative erkrankungen
CA2401546C (en) * 2002-09-06 2006-09-19 Brantford Chemicals Inc. Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine
ITMI20022749A1 (it) * 2002-12-23 2004-06-24 Cosma S P A Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20050215600A1 (en) * 2003-10-27 2005-09-29 Arie Gutman Polymorphs of torsemide hydrochloride and process for production thereof
US7378527B2 (en) * 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
JP2009511629A (ja) * 2005-10-17 2009-03-19 ニューロセラピューティクス ファーマ， インコーポレイテッド 中枢神経系疾患の調節に有用な利尿薬様化合物類似体
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) * 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
EP2148861A1 (de) * 2007-05-16 2010-02-03 F. Hoffmann-Roche AG Arylpyridylsulfonamidderivate, ihre herstellung und verwendung als arzneimittel
NL2006622C2 (en) 2011-04-18 2012-10-22 Eurovet Animal Health B V Use of a composition comprising torasemide.
US9616075B2 (en) 2012-07-20 2017-04-11 University Of Rochester Method of treating and preventing brain impairment using Na+-K+-2Cl-cotransporter isoform 1 inhibitors
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
HUE055755T2 (hu) * 2015-02-16 2021-12-28 Univ Queensland Szulfonolkarmabidok és rokon vegyületeik valamint felhasználásuk
KR102669722B1 (ko) 2017-07-07 2024-05-29 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof
US12599616B2 (en) * 2020-02-28 2026-04-14 Zydus Lifesciences Limited Subtituted sulfonylurea and sulfoximineurea derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives

Also Published As

Publication number Publication date
DE2516025A1 (de) 1975-11-06
US4018929A (en) 1977-04-19
CH609045A5 (de) 1979-02-15
SE7504409L (sv) 1975-10-20
CA1070313A (en) 1980-01-22
CH610890A5 (de) 1979-05-15
ES453329A1 (es) 1977-11-16
LU72284A1 (de) 1975-08-20
FR2267775B1 (de) 1978-11-10
USRE30633E (en) 1981-06-02
AT344170B (de) 1978-07-10
NL7504521A (nl) 1975-10-21
GB1477664A (en) 1977-06-22
ES453327A1 (es) 1977-11-16
IL47084A0 (en) 1975-06-25
AU8001675A (en) 1976-10-14
SE7907618L (sv) 1979-09-13
BE827844A (fr) 1975-10-13
YU150781A (en) 1984-02-29
NL940014I1 (nl) 1994-09-16
ES453328A1 (es) 1977-11-01
LU88346I2 (fr) 1994-05-04
SE424320B (sv) 1982-07-12
AR211097A1 (es) 1977-10-31
DD126887A5 (de) 1977-08-17
CH612424A5 (de) 1979-07-31
JPS50142571A (de) 1975-11-17
NL940014I2 (nl) 1997-04-01
IL47084A (en) 1979-01-31
NL183580C (nl) 1988-12-01
AR208768A1 (es) 1977-02-28
AR208769A1 (es) 1977-02-28
DD121936A5 (de) 1976-09-05
NL183580B (nl) 1988-07-01
AR208770A1 (es) 1977-02-28
JPS5951536B2 (ja) 1984-12-14
ZA752243B (en) 1976-03-31
FR2267775A1 (de) 1975-11-14
HU171420B (hu) 1978-01-28
DE2516025C2 (de) 1988-11-03
ES436581A1 (es) 1977-04-01
YU42409B (en) 1988-08-31

Similar Documents

Publication Publication Date Title
AT344170B (de) Verfahren zur herstellung neuer pyridinderivate und ihrer n-oxide und salze
AT352736B (de) Verfahren zur herstellung neuer chinazolon- derivate und ihrer salze
AT333277B (de) Verfahren zur herstellung von neuen oxazolpyridinen und deren n-oxiden und quaternaren pyridiniumsalzen
AT355565B (de) Verfahren zur herstellung neuer thiazolin- derivate und ihrer salze
AT351542B (de) Verfahren zur herstellung neuer homophthalimide und ihrer salze
ATA498876A (de) Verfahren zur herstellung neuer 2-benzopyranon- derivate und ihrer salze
AT316549B (de) Verfahren zur Herstellung neuer Pyridin-Derivate und ihrer Säureadditionssalze
AT342033B (de) Verfahren zur herstellung neuer phenylbutanolderivate und ihrer salze
AT330174B (de) Verfahren zur herstellung neuer piperidin-derivate und von deren salzen
AT353259B (de) Verfahren zur herstellung neuer 3-nitropyrazol- derivate und deren salze
AT344175B (de) Verfahren zur herstellung neuer pyridinderivate und ihrer salze
ATA189877A (de) Verfahren zur herstellung neuer pyridinderivate und ihrer salze
ATA189777A (de) Verfahren zur herstellung neuer pyridinderivate und ihrer salze
ATA8579A (de) Verfahren zur herstellung neuer chinazolon- derivate und ihrer salze
AT341526B (de) Verfahren zur herstellung neuer, in 5-stellung substituierten chinolincarbonsaure-derivate und ihrer salze
AT350745B (de) Verfahren zur herstellung neuer 8- azaprostansaeurederivate und deren salzen
AT350557B (de) Verfahren zur herstellung neuer thiazolderivate und ihrer salze
AT258285B (de) Verfahren zur Herstellung neuer 4,5,6,7-Tetrahydro-thiazolo-[5,4-c]pyridine und ihrer Salze
AT310748B (de) Verfahren zur Herstellung neuer Indeno[1,2-c]pyridine und ihrer Säureadditionssalze
ATA579476A (de) Verfahren zur herstellung neuer 3-iminoalkyl-2 (1h)-pyridone und ihrer saeureadditionssalze
AT312610B (de) Verfahren zur Herstellung neuer (4aRS,5SR,9bRS)-1,3,4,4a,5,9b-Hexahydro-5-phenyl-2H-indeno[1,2-c]pyridine und ihrer Säureadditionssalze
DD130784A1 (de) Verfahren zur herstellung von pyridin und 3-methylpyridin
ATA166377A (de) Verfahren zur herstellung neuer phenyl- butanolderivate und ihrer salze
AT312605B (de) Verfahren zur Herstellung neuer (4aRS, 5SR, 9bSR)- und (4aRS, 5SR, 9bRS)-1,3,4,4a,5,9b-Hexahydro-5-phenyl-2H-indeno[1,2-c]pyridine und ihrer Säureadditionssalze
AT350556B (de) Verfahren zur herstellung neuer thiazolderivate und ihrer salze

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee