ATA308986A - Menschliche mangan-superoxiddismutase cdna, ihre expression in bakterien und verfahren zur gewinnung enzymatisch aktiver, menschlicher mangan-superoxiddismutase - Google Patents

Menschliche mangan-superoxiddismutase cdna, ihre expression in bakterien und verfahren zur gewinnung enzymatisch aktiver, menschlicher mangan-superoxiddismutase

Info

Publication number
ATA308986A
ATA308986A AT0308986A AT308986A ATA308986A AT A308986 A ATA308986 A AT A308986A AT 0308986 A AT0308986 A AT 0308986A AT 308986 A AT308986 A AT 308986A AT A308986 A ATA308986 A AT A308986A
Authority
AT
Austria
Prior art keywords
manganese superoxide
human manganese
disismutase
bacteria
expression
Prior art date
Application number
AT0308986A
Other languages
English (en)
Other versions
AT400443B (de
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of ATA308986A publication Critical patent/ATA308986A/de
Application granted granted Critical
Publication of AT400443B publication Critical patent/AT400443B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT0308986A 1985-11-22 1986-11-19 Menschliche mangan-superoxiddismutase cdna, ihre expression in bakterien und verfahren zur gewinnung enzymatisch aktiver, menschlicher mangan-superoxiddismutase AT400443B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (2)

Publication Number Publication Date
ATA308986A true ATA308986A (de) 1995-05-15
AT400443B AT400443B (de) 1995-12-27

Family

ID=27122291

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0308986A AT400443B (de) 1985-11-22 1986-11-19 Menschliche mangan-superoxiddismutase cdna, ihre expression in bakterien und verfahren zur gewinnung enzymatisch aktiver, menschlicher mangan-superoxiddismutase

Country Status (21)

Country Link
JP (2) JP2609449B2 (de)
AT (1) AT400443B (de)
AU (1) AU607897B2 (de)
BE (1) BE905796A (de)
CA (1) CA1341362C (de)
CH (1) CH676990A5 (de)
DE (1) DE3639725C2 (de)
DK (1) DK534686A (de)
ES (1) ES2003518A6 (de)
FI (1) FI90353C (de)
FR (1) FR2590591B1 (de)
GB (1) GB2183658B (de)
GR (1) GR862713B (de)
HK (1) HK75195A (de)
IE (1) IE59498B1 (de)
IL (2) IL80702A0 (de)
IT (1) IT1205418B (de)
LU (1) LU86676A1 (de)
NL (1) NL8602960A (de)
PT (1) PT83792B (de)
SE (1) SE8604884L (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS62215532A (ja) * 1986-03-18 1987-09-22 Ube Ind Ltd 抗炎症剤
JPH0643341B2 (ja) * 1986-03-27 1994-06-08 宇部興産株式会社 臓器機能改善剤
JPH0643340B2 (ja) * 1986-09-03 1994-06-08 宇部興産株式会社 虚血性心疾患治療薬
JPS6377822A (ja) * 1986-09-18 1988-04-08 Ube Ind Ltd 臓器機能改善剤
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
EP0282899B1 (de) * 1987-03-14 1996-01-10 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Humane Mangan-Superoxiddismutase (hMn-SOD)
EP0691401A1 (de) * 1987-03-27 1996-01-10 Bio-Technology General Corporation Menschliche Mangansuperoxiddismutase-Analogen, diese enthaltende pharmazeutische Zusammensetzungen und deren Verwendung
JPH01233228A (ja) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd 悪性腫瘍細胞転移防止剤
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (de) * 1990-12-04 1992-06-11 Gruenenthal Gmbh Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma
PT587055E (pt) * 1992-09-09 2002-05-31 Bio Technology General Corp Utilizacao de manganes superoxidodismutase (mn-sod) para a preparacao de medicamentos para o tratamento de doencas em pequenas dosagens
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
WO2025178510A1 (ru) * 2024-02-21 2025-08-28 Евгений Владимирович ГРИГОРЬЕВ Способ применения супероксиддисмутазы 2 в качестве антиоксиданта в сверхмалых дозировках

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
DE3486452T2 (de) * 1983-10-03 1997-11-06 Chiron Corp., Emeryville, Calif. Superoxiddismutase und deren Expression in Mikroorganismen

Also Published As

Publication number Publication date
GB2183658A (en) 1987-06-10
IL106449A (en) 1997-02-18
LU86676A1 (fr) 1987-05-04
IT1205418B (it) 1989-03-15
IE59498B1 (en) 1994-03-09
AU6497586A (en) 1987-05-28
PT83792A (en) 1986-12-01
FR2590591A1 (fr) 1987-05-29
DK534686D0 (da) 1986-11-07
IL106449A0 (en) 1993-11-15
GR862713B (en) 1987-03-24
IL80702A0 (en) 1987-02-27
IE862851L (en) 1987-05-22
DE3639725A1 (de) 1987-07-23
FI864756A0 (fi) 1986-11-21
HK75195A (en) 1995-05-26
JP2609449B2 (ja) 1997-05-14
FI90353C (fi) 1994-01-25
JP2967557B2 (ja) 1999-10-25
AT400443B (de) 1995-12-27
CA1341362C (en) 2002-05-28
CH676990A5 (de) 1991-03-28
PT83792B (pt) 1989-01-17
IT8667865A0 (it) 1986-11-21
GB8627294D0 (en) 1986-12-17
SE8604884L (sv) 1987-05-23
SE8604884D0 (sv) 1986-11-14
AU607897B2 (en) 1991-03-21
DE3639725C2 (de) 1998-02-19
NL8602960A (nl) 1987-06-16
JPS62289187A (ja) 1987-12-16
DK534686A (da) 1987-05-23
GB2183658B (en) 1990-04-25
JPH08289792A (ja) 1996-11-05
FI864756A7 (fi) 1987-05-23
FI90353B (fi) 1993-10-15
BE905796A (fr) 1987-03-16
FR2590591B1 (fr) 1989-12-01
ES2003518A6 (es) 1988-11-01

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