ATE100444T1 - Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten. - Google Patents

Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten.

Info

Publication number: ATE100444T1
Authority: AT; Austria
Prior art keywords: alkyl; optically active; preparation; benzenesulfonamide derivatives; group
Prior art date: 1986-07-21

Application number

AT90104584T

Other languages

English (en)

Inventor

Minoru Okada

Koichi Yoshida

Kiyoshi Takanobu

Original Assignee

Yamanouchi Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-21

Filing date

1990-03-10

Publication date

1994-02-15

1990-03-10 Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd

1994-02-15 Application granted granted Critical

1994-02-15 Publication of ATE100444T1 publication Critical patent/ATE100444T1/de

Links

150000008331 benzenesulfonamides Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT90104584T 1986-07-21 1990-03-10 Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten. ATE100444T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP61172285A JPH066565B2 (ja)	1986-07-21	1986-07-21	光学活性なベンゼンスルホンアミド誘導体の製造法
EP90104584A EP0380144B1 (de)	1986-07-21	1987-07-21	Verfahren zur Herstellung von optisch aktiven Benzolsulfonamidderivaten

Publications (1)

Publication Number	Publication Date
ATE100444T1 true ATE100444T1 (de)	1994-02-15

Family

ID=15939091

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT87306453T ATE62667T1 (de)	1986-07-21	1987-07-21	Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten.
AT90104584T ATE100444T1 (de)	1986-07-21	1990-03-10	Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT87306453T ATE62667T1 (de)	1986-07-21	1987-07-21	Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten.

Country Status (8)

Country	Link
EP (2)	EP0380144B1 (de)
JP (1)	JPH066565B2 (de)
KR (1)	KR960003810B1 (de)
AT (2)	ATE62667T1 (de)
CA (1)	CA1340332C (de)
DE (2)	DE3788878T2 (de)
ES (2)	ES2062136T3 (de)
IE (1)	IE63344B1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4971990A (en) *	1988-02-19	1990-11-20	Hokuriku Pharmaceutical Co., Ltd.	Phenoxyethylamine derivatives, for preparing the same and composition for exhibiting excellent α1 -blocking activity containing the same
JPH0345780A (ja) *	1989-07-12	1991-02-27	Minoru Ban	絹繊維製品の化学的加工法
US5288759A (en) *	1992-08-27	1994-02-22	Alcon Laboratories, Inc.	Use of certain sulfamoyl-substituted phenethylamine derivatives to reverse drug-induced mydriasis
JP2002513799A (ja)	1998-05-06	2002-05-14	デューク・ユニバーシティー	膀胱および下部尿路症候群の治療方法
US6835853B2 (en) *	2001-10-31	2004-12-28	Synthon Bv	Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
ES2200699B1 (es) *	2002-07-12	2005-10-01	Ragactives, S.L	Procedimiento para la separacion de r(-) y s(+)-5-(2-((2-(etoxifenoxi)etil)amino)propil-2-metoxibenceno-sulfonamida.
HU225505B1 (en) *	2002-09-09	2007-01-29	Richter Gedeon Vegyeszet	Process for the preparation of r-(-)-tamsulosin hydrochloride and novel intermediates
DE60232201D1 (de) *	2002-12-26	2009-06-10	Cadila Healthcare Ltd	Verfahren zur zubereitung von enantiomerisch reinem (r) oder (s)-5-(2-aminopropyl)-2-methoxybenzensulfonamid
JP2007513943A (ja)	2003-12-09	2007-05-31	シージェイコーポレーション	光学的に純粋なフェネチルアミン誘導体の調製方法
SI21702A (en) *	2004-01-29	2005-08-31	Lek Farmacevtska Druzba Dd	Preparation of amorphous form of tamsulosin
CZ2004197A3 (cs)	2004-02-05	2005-08-17	Zentiva, A. S.	Způsob výroby (R)-(-)-5-(2-aminopropyl)-2-methoxybenzensulfonamidu
US20080033208A1 (en) *	2004-02-23	2008-02-07	Dilipkumar Chandubhai Ramolia	Process for Manufacturing Optically Pure (R) or (S)-5-(2-Aminopropyl)-2-Methoxybenzene Sulfonamide
JP4800213B2 (ja) *	2004-07-07	2011-10-26	浜理薬品工業株式会社	光学活性フェニルプロピルアミン誘導体の製法
CN100545148C (zh) *	2004-08-16	2009-09-30	神隆新加坡私人有限公司	一种抗良性前列腺肥大药物坦索罗辛之合成方法
US7238839B2 (en)	2004-10-07	2007-07-03	Divi's Laboratories Limited	Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)Propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation
KR101144776B1 (ko) *	2004-12-02	2012-05-11	연성정밀화학(주)	광학 활성 벤젠설폰아마이드 유도체의 제조방법
PT103216B (pt)	2004-12-06	2010-05-19	Hovione Farmaciencia S A	Preparação de tamsulosin
US8273918B2 (en)	2005-09-12	2012-09-25	Avrobindo Pharma Ltd.	Process for preparing tamsulosin hydrochloride
EP2026766A1 (de)	2006-05-17	2009-02-25	Synthon B.V.	Tabletten-zusammensetzung mit verlängerter freisetzung von tamsulosin
CN101190890B (zh)	2006-11-30	2011-04-27	江苏豪森药业股份有限公司	5-[(2r)-[2-[2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基]氨基]丙基]-2-甲氧基苯磺酰胺
WO2009005024A1 (ja)	2007-07-03	2009-01-08	Hamari Chemicals, Ltd.	光学活性アミンの製造方法
EP2233465B1 (de)	2008-01-10	2017-06-28	Shanghai Institute of Pharmaceutical Industry	Verfahren zur herstellung von rivastigmin, dessen zwischenprodukte und verfahren zur herstellung der zwischenprodukte
CN101284807B (zh) *	2008-06-11	2010-12-08	药源药物化学（上海）有限公司	盐酸坦索罗辛的制备方法
US8465770B2 (en)	2008-12-24	2013-06-18	Synthon Bv	Low dose controlled release tablet
EP2255793A1 (de)	2009-05-28	2010-12-01	Krka Tovarna Zdravil, D.D., Novo Mesto	Pharmazeutische Zusammensetzung mit Tamsulosin
DE102012022670A1 (de)	2012-11-21	2014-05-22	Friedrich-Alexander-Universität Erlangen-Nürnberg	Verfahren zur Herstellung enantiomerenangereicherter und enantiomerenreiner Nitroalkane und Amine
CN111320559A (zh) *	2018-12-14	2020-06-23	苏州盛迪亚生物医药有限公司	一种盐酸坦索罗辛的制备方法
DE202023102187U1 (de)	2023-04-25	2023-05-02	Nusrath Anjum	Auf Tamsulosin basierende Derivatformulierung
CN117024314B (zh) *	2023-08-09	2025-07-18	常州瑞明药业有限公司	一种(r)-5-(2-氨基丙基)-2-甲氧基苯磺酰胺的合成方法
CN119019296A (zh) *	2024-10-24	2024-11-26	江苏恒瑞医药股份有限公司	一种固载催化剂制备坦索罗辛或其可药用盐的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4000197A (en) *	1973-07-23	1976-12-28	The University Of Iowa Research Foundation	Asymmetric synthesis of phenylisopropylamines
JPS56110665A (en) *	1980-02-08	1981-09-01	Yamanouchi Pharmaceut Co Ltd	Sulfamoyl-substituted phenetylamine derivative and its preparation
US4658060A (en) *	1982-04-26	1987-04-14	Schering Corporation	Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide

1986
- 1986-07-21 JP JP61172285A patent/JPH066565B2/ja not_active Expired - Lifetime
1987
- 1987-07-20 KR KR1019870007809A patent/KR960003810B1/ko not_active Expired - Lifetime
- 1987-07-20 CA CA000542529A patent/CA1340332C/en not_active Expired - Lifetime
- 1987-07-20 IE IE196087A patent/IE63344B1/en not_active IP Right Cessation
- 1987-07-21 EP EP90104584A patent/EP0380144B1/de not_active Expired - Lifetime
- 1987-07-21 ES ES90104584T patent/ES2062136T3/es not_active Expired - Lifetime
- 1987-07-21 EP EP87306453A patent/EP0257787B1/de not_active Expired - Lifetime
- 1987-07-21 DE DE90104584T patent/DE3788878T2/de not_active Expired - Lifetime
- 1987-07-21 DE DE8787306453T patent/DE3769399D1/de not_active Expired - Lifetime
- 1987-07-21 ES ES198787306453T patent/ES2029838T3/es not_active Expired - Lifetime
- 1987-07-21 AT AT87306453T patent/ATE62667T1/de not_active IP Right Cessation
1990
- 1990-03-10 AT AT90104584T patent/ATE100444T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2029838T3 (es)	1992-10-01
IE63344B1 (en)	1995-04-19
JPS6327471A (ja)	1988-02-05
DE3769399D1 (de)	1991-05-23
EP0257787A1 (de)	1988-03-02
EP0380144B1 (de)	1994-01-19
CA1340332C (en)	1999-01-26
KR960003810B1 (ko)	1996-03-22
ATE62667T1 (de)	1991-05-15
DE3788878T2 (de)	1994-05-05
JPH066565B2 (ja)	1994-01-26
IE871960L (en)	1988-01-21
KR880001583A (ko)	1988-04-25
DE3788878D1 (de)	1994-03-03
ES2062136T3 (es)	1994-12-16
EP0380144A1 (de)	1990-08-01
EP0257787B1 (de)	1991-04-17

Legal Events

Date	Code	Title
1994-10-15	UEP	Publication of translation of european patent specification
2006-04-15	EEFA	Change of the company name
2007-10-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE100444T1 (de)	1994-02-15	Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten.
DE69103413D1 (de)	1994-09-15	Verfahren zur enantioselektiven herstellung von phenylisoserinderivaten.
NO306062B1 (no)	1999-09-13	Syremellomprodukter til bruk ved fremstilling av taxanderivater
ATE35417T1 (de)	1988-07-15	Verfahren zur herstellung von phosphorhaltigen cyanhydrinderivaten.
EP0262806A3 (de)	1990-01-17	Organosilikonverbindung
ATE77818T1 (de)	1992-07-15	Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung.
KR890012991A (ko)	1989-09-20	광학활성을 갖는 4-옥소-1-벤조피란-2-카르복시산 유도체 및 중간체의 제법
SE8403268L (sv)	1984-12-22	1,4-dihydropyridinderivat, deras framstellning och farmaceutiska beredningar innehallande dessa
ATE38665T1 (de)	1988-12-15	Verfahren zur herstellung von 5-perfluoralkyl-5,6-dihydrouracyl-derivaten und verwendbare zwischenprodukte.
ATE30718T1 (de)	1987-11-15	Herstellung von 1-benzyl azetidin-3-ol und von dem entsprechenden halid acid.
SE7905330L (sv)	1979-12-21	Nya cykliska acetaler
ATE87307T1 (de)	1993-04-15	Isoindolinderivate und verfahren zu ihrer herstellung.
ATE34740T1 (de)	1988-06-15	(bis(hydroxymethyl)methyl)-isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE36321T1 (de)	1988-08-15	(bis(substituiertes methyl)methyl>isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE113593T1 (de)	1994-11-15	Verfahren zur herstellung von polyalkyl-2-alkoxy- 7-hydroxychromanderivate.
ATE39688T1 (de)	1989-01-15	Verfahren zur herstellung von aminotriazinonderivaten.
MY102457A (en)	1992-06-30	Isoquinoline derivatives
EP0149534A3 (de)	1987-09-09	Thioketen-Derivate und Verfahren zur Herstellung
ATE75747T1 (de)	1992-05-15	Verfahren zur herstellung von antibiotika.
ATE29711T1 (de)	1987-10-15	Verfahren zur herstellung von ethylenglykol.
DK389683D0 (da)	1983-08-25	Fremgangsmade til fremstilling af substituerede 1,3,4-benzotriazepiner eller farmaceutisk acceptable syreadditionssalte deraf
EP0281326A3 (de)	1989-10-18	Norbornadienderivate
ATE90101T1 (de)	1993-06-15	Verfahren zur herstellung von makrolid-derivaten.
DK1056769T3 (da)	2002-10-14	15-methyl-cyclopropanosteroider og fremgangsmåde til deres fremstilling
TH21847A (th)	1996-11-20	สารประกอบบิสฟอสไฟท์ และวิธีการผลิตแอลดีไฮด์