ATE102184T1 - Piperazine-derivate. - Google Patents
Piperazine-derivate.Info
- Publication number
- ATE102184T1 ATE102184T1 AT89313371T AT89313371T ATE102184T1 AT E102184 T1 ATE102184 T1 AT E102184T1 AT 89313371 T AT89313371 T AT 89313371T AT 89313371 T AT89313371 T AT 89313371T AT E102184 T1 ATE102184 T1 AT E102184T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- piperazine derivatives
- sterotonin
- isomeres
- aggression
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 102000017911 HTR1A Human genes 0.000 abstract 1
- 101150015707 HTR1A gene Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000016571 aggressive behavior Effects 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000005095 gastrointestinal system Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000005227 renal system Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888830312A GB8830312D0 (en) | 1988-12-28 | 1988-12-28 | Heterocyclic compounds |
| EP89313371A EP0376607B1 (de) | 1988-12-28 | 1989-12-20 | Piperazine-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE102184T1 true ATE102184T1 (de) | 1994-03-15 |
Family
ID=10649223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89313371T ATE102184T1 (de) | 1988-12-28 | 1989-12-20 | Piperazine-derivate. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5002948A (de) |
| EP (1) | EP0376607B1 (de) |
| JP (1) | JP2895121B2 (de) |
| AT (1) | ATE102184T1 (de) |
| AU (1) | AU637991B2 (de) |
| CA (1) | CA2006356C (de) |
| DE (1) | DE68913487T2 (de) |
| DK (1) | DK169266B1 (de) |
| ES (1) | ES2062050T3 (de) |
| FI (1) | FI93005C (de) |
| GB (1) | GB8830312D0 (de) |
| IE (1) | IE62668B1 (de) |
| IL (1) | IL92990A (de) |
| NO (1) | NO174772C (de) |
| NZ (1) | NZ231855A (de) |
| PT (1) | PT92728B (de) |
| ZA (1) | ZA899960B (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3923045A1 (de) * | 1989-07-13 | 1991-01-17 | Merck Patent Gmbh | Indolderivate |
| EP0465254B1 (de) * | 1990-07-06 | 1996-11-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Kondensierte Thiophenverbindungen und deren Verwendung |
| US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
| FR2670491B1 (fr) * | 1990-12-14 | 1993-02-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
| DE4101686A1 (de) | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| DE4127849A1 (de) * | 1991-08-22 | 1993-02-25 | Merck Patent Gmbh | Benzodioxanderivate |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
| DK55192D0 (da) * | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
| FR2692264B1 (fr) * | 1992-06-12 | 1994-08-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| ES2050623B1 (es) * | 1992-11-06 | 1994-12-16 | Merck Patent Gmbh | Derivados de 1,4-benzodioxano. |
| DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
| KR950704252A (ko) * | 1992-12-21 | 1995-11-17 | 우에하라 아키라 | N-치환 이미다졸 유도체 |
| GB9305623D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
| RU2118322C1 (ru) * | 1993-07-05 | 1998-08-27 | Дюфар Интернэшнл Рисерч Б.В. | 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли |
| DE4333254A1 (de) * | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
| US5552402A (en) * | 1994-05-19 | 1996-09-03 | Merck, Sharp & Dohme Ltd. | Five-membered heteroaromatic compounds as 5-HT receptor agonists |
| DE19512639A1 (de) | 1995-04-05 | 1996-10-10 | Merck Patent Gmbh | Benzonitrile und -fluoride |
| EP0829474B1 (de) * | 1995-05-31 | 2003-04-09 | Nisshin Seifun Group Inc. | Indazolderivate mit einer cyclischen aminogruppe |
| JPH09124643A (ja) * | 1995-08-14 | 1997-05-13 | Bristol Myers Squibb Co | 抗うつ作用を有する1−アリールアルキル−4−(アルコキシピリジニル)−又は4−(アルコキシピリミジニル)ピペラジン誘導体 |
| WO1998008816A1 (en) * | 1996-08-26 | 1998-03-05 | Meiji Seika Kaisha, Ltd. | Oxindole derivatives and psychotropic drugs |
| AR013206A1 (es) * | 1997-07-25 | 2000-12-13 | Lundbeck & Co As H | Derivados indol y 2,3-dihidroindol, composiciones farmaceuticas que contienen estos compuestos y el uso de dichos compuestos para la preparacion de un medicamento para el tratamiento de desordenes sensibles a la inhibicion de la reabsorcion de serotonina y antagonismo de receptores 5-ht1a. |
| CZ295937B6 (cs) * | 1997-07-25 | 2005-12-14 | H. Lundbeck A/S | Indolové nebo 2,3-dihydroindolové deriváty |
| JP2002510676A (ja) * | 1998-04-08 | 2002-04-09 | アメリカン・ホーム・プロダクツ・コーポレイション | うつ病治療用のn−アリールオキシエチルアミン誘導体 |
| AR022303A1 (es) * | 1999-01-22 | 2002-09-04 | Lundbeck & Co As H | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion |
| AU772189B2 (en) * | 1999-08-23 | 2004-04-08 | Solvay Pharmaceuticals B.V. | New phenylpiperazines |
| DE60009154D1 (de) * | 1999-12-30 | 2004-04-22 | Lundbeck & Co As H | Phenylpiperazinyl-derivate |
| AR027134A1 (es) * | 1999-12-30 | 2003-03-12 | Lundbeck & Co As H | Derivados de indol. |
| EA006071B1 (ru) * | 1999-12-30 | 2005-08-25 | Х.Лундбекк А/С | Замещенные производные фенилпиперазина, их получение и применение |
| US6897231B2 (en) * | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
| US7211594B2 (en) * | 2000-07-31 | 2007-05-01 | Signal Pharmaceuticals, Llc | Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith |
| AR035521A1 (es) * | 2000-12-22 | 2004-06-02 | Lundbeck & Co As H | Derivados de 3-indolina y composicion farmaceutica que los comprende |
| AR032712A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| US7041683B2 (en) | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
| EP1381600A1 (de) * | 2001-04-24 | 2004-01-21 | Wyeth, A Corporation of the State of Delaware | Azaheterocyclylmethyldeivate von 2,3-dihydro-1,4-benzodioxan als antidepressiva |
| ATE424825T1 (de) | 2001-07-20 | 2009-03-15 | Psychogenics Inc | Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten |
| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| KR20050085472A (ko) * | 2002-12-10 | 2005-08-29 | 메르크 파텐트 게엠베하 | 인돌 유도체 및 5-ht 리간드로서의 이의 용도 |
| US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| DE10326939A1 (de) * | 2003-06-16 | 2005-01-05 | Merck Patent Gmbh | Indol-Derivate |
| DE10326940A1 (de) * | 2003-06-16 | 2005-01-05 | Merck Patent Gmbh | Indol-Derivate |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| MXPA06012059A (es) * | 2004-04-22 | 2007-01-25 | Boehringer Ingelheim Int | Nuevas composiciones farmaceuticas para el tratamiento de los trastornos sexuales ii. |
| WO2005108390A1 (en) * | 2004-05-11 | 2005-11-17 | Egis Gyógyszergyár Nyrt. | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
| EP1751134A1 (de) * | 2004-05-11 | 2007-02-14 | EGIS Gyógyszergyár Nyrt | Pyridinderivate von alkyloxindolen als auf den 5-ht7-rezeptor wirkende mittel |
| RS20060620A (sr) * | 2004-05-11 | 2008-09-29 | Egis Gyogyszergyar Nyrt., | Piperazinski derivati alkil oksindola |
| HUP0400953A3 (en) * | 2004-05-11 | 2008-02-28 | Egis Gyogyszergyar Nyilvanosan | Piperazine derivatives of alkyl-oxindoles, pharmaceutical compositions containing them, process for producing them and their use |
| MXPA06013069A (es) * | 2004-05-11 | 2007-03-30 | Egis Gyogyszergyar Nyrt | Derivados de 3-(((4-fenil) -piperazin-1-il) -alquil)-3 -alquil-1, 3-dihidro-2h -indol-2 -ona y compuestos relacionados para el tratamiento de trastornos del sistema nervioso central. |
| US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
| CA2576812A1 (en) * | 2004-09-03 | 2006-03-09 | Boehringer Ingelheim International Gmbh | Method for the treatment of attention deficit hyperactivity disorder |
| TW200631952A (en) * | 2004-12-07 | 2006-09-16 | Solvay Pharm Bv | Benzdioxan piperazine derivatives with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
| US7371769B2 (en) | 2004-12-07 | 2008-05-13 | Solvay Pharmaceuticals B.V. | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
| US20070072870A2 (en) | 2004-12-08 | 2007-03-29 | Solvay Pharmeceuticals B.V. | Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
| WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
| JP2008538741A (ja) * | 2005-03-04 | 2008-11-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 鬱病の治療用及び/又は予防用の医薬組成物 |
| JP2008531714A (ja) * | 2005-03-04 | 2008-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 不安障害の治療用及び/又は予防用の医薬組成物 |
| US20070004777A1 (en) * | 2005-03-23 | 2007-01-04 | Bhagwat Shripad S | Methods for treating or preventing acute myelogenous leukemia |
| EP1904182A2 (de) * | 2005-05-06 | 2008-04-02 | Boehringer Ingelheim International GmbH | Verfahren zur behandlung von drogenmissbrauch mit flibanserin |
| JP2008540672A (ja) * | 2005-05-19 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 病状に起因する性的機能不全の治療方法 |
| JP2008540673A (ja) * | 2005-05-19 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 薬剤誘発性性機能不全の治療方法 |
| ES2646326T3 (es) | 2005-08-03 | 2017-12-13 | Sprout Pharmaceuticals, Inc. | Uso de flibanserina en el tratamiento de la obesidad |
| CA2626134C (en) | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| BRPI0712039A2 (pt) * | 2006-05-09 | 2011-12-20 | Boehringer Ingelheim Int | uso de flibanserina para o tratamento de distúrbios de desejo sexual pós-menopausa |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| US20090318469A1 (en) * | 2006-07-14 | 2009-12-24 | Boehringer Ingelheim International Gmbh | Use of Flibanserin for the Treatment of Sexual Disorders in Females |
| EP2054041A2 (de) | 2006-08-14 | 2009-05-06 | Boehringer Ingelheim International GmbH | Formulierungen von flibanserin und herstellungsverfahren dafür |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| IL197129A (en) | 2006-08-25 | 2014-08-31 | Boehringer Ingelheim Int | Controlled release system and method for production |
| CL2008002693A1 (es) * | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| CN102574787B (zh) * | 2009-07-30 | 2014-12-31 | 新加坡国立大学 | 具有潜在的抗癌活性的小分子异戊二烯基半胱氨酸羧基甲基转移酶抑制剂 |
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| US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| DE3923045A1 (de) * | 1989-07-13 | 1991-01-17 | Merck Patent Gmbh | Indolderivate |
-
1988
- 1988-12-28 GB GB888830312A patent/GB8830312D0/en active Pending
-
1989
- 1989-12-12 IE IE397689A patent/IE62668B1/en not_active IP Right Cessation
- 1989-12-19 NZ NZ231855A patent/NZ231855A/en unknown
- 1989-12-19 DK DK645689A patent/DK169266B1/da not_active IP Right Cessation
- 1989-12-20 AT AT89313371T patent/ATE102184T1/de not_active IP Right Cessation
- 1989-12-20 DE DE68913487T patent/DE68913487T2/de not_active Expired - Fee Related
- 1989-12-20 EP EP89313371A patent/EP0376607B1/de not_active Expired - Lifetime
- 1989-12-20 ES ES89313371T patent/ES2062050T3/es not_active Expired - Lifetime
- 1989-12-21 CA CA002006356A patent/CA2006356C/en not_active Expired - Lifetime
- 1989-12-22 AU AU47198/89A patent/AU637991B2/en not_active Ceased
- 1989-12-26 US US07/456,938 patent/US5002948A/en not_active Expired - Lifetime
- 1989-12-27 JP JP1336755A patent/JP2895121B2/ja not_active Expired - Fee Related
- 1989-12-27 PT PT92728A patent/PT92728B/pt not_active IP Right Cessation
- 1989-12-27 NO NO895281A patent/NO174772C/no not_active IP Right Cessation
- 1989-12-28 ZA ZA899960A patent/ZA899960B/xx unknown
- 1989-12-28 FI FI896300A patent/FI93005C/fi active IP Right Grant
-
1990
- 1990-01-07 IL IL9299090A patent/IL92990A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB8830312D0 (en) | 1989-02-22 |
| FI93005B (fi) | 1994-10-31 |
| DE68913487D1 (de) | 1994-04-07 |
| DK645689A (da) | 1990-06-29 |
| PT92728B (pt) | 1995-12-29 |
| DE68913487T2 (de) | 1994-08-04 |
| EP0376607B1 (de) | 1994-03-02 |
| IL92990A0 (en) | 1990-09-17 |
| DK169266B1 (da) | 1994-09-26 |
| EP0376607A1 (de) | 1990-07-04 |
| JPH02225460A (ja) | 1990-09-07 |
| IE62668B1 (en) | 1995-02-22 |
| ES2062050T3 (es) | 1994-12-16 |
| ZA899960B (en) | 1990-11-28 |
| FI93005C (fi) | 1995-02-10 |
| NO174772B (no) | 1994-03-28 |
| CA2006356A1 (en) | 1990-06-28 |
| NO895281L (no) | 1990-06-29 |
| NO174772C (no) | 1994-07-06 |
| IE893976L (en) | 1990-06-13 |
| PT92728A (pt) | 1990-06-29 |
| AU4719889A (en) | 1990-07-05 |
| DK645689D0 (da) | 1989-12-19 |
| NZ231855A (en) | 1992-02-25 |
| FI896300A0 (fi) | 1989-12-28 |
| AU637991B2 (en) | 1993-06-17 |
| JP2895121B2 (ja) | 1999-05-24 |
| IL92990A (en) | 1995-01-24 |
| CA2006356C (en) | 1999-09-14 |
| US5002948A (en) | 1991-03-26 |
| NO895281D0 (no) | 1989-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |