ATE102184T1 - Piperazine-derivate. - Google Patents

Piperazine-derivate.

Info

Publication number
ATE102184T1
ATE102184T1 AT89313371T AT89313371T ATE102184T1 AT E102184 T1 ATE102184 T1 AT E102184T1 AT 89313371 T AT89313371 T AT 89313371T AT 89313371 T AT89313371 T AT 89313371T AT E102184 T1 ATE102184 T1 AT E102184T1
Authority
AT
Austria
Prior art keywords
compounds
piperazine derivatives
sterotonin
isomeres
aggression
Prior art date
Application number
AT89313371T
Other languages
English (en)
Inventor
Jens Perregaard
John Willie Stenberg
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE102184T1 publication Critical patent/ATE102184T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT89313371T 1988-12-28 1989-12-20 Piperazine-derivate. ATE102184T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888830312A GB8830312D0 (en) 1988-12-28 1988-12-28 Heterocyclic compounds
EP89313371A EP0376607B1 (de) 1988-12-28 1989-12-20 Piperazine-Derivate

Publications (1)

Publication Number Publication Date
ATE102184T1 true ATE102184T1 (de) 1994-03-15

Family

ID=10649223

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89313371T ATE102184T1 (de) 1988-12-28 1989-12-20 Piperazine-derivate.

Country Status (17)

Country Link
US (1) US5002948A (de)
EP (1) EP0376607B1 (de)
JP (1) JP2895121B2 (de)
AT (1) ATE102184T1 (de)
AU (1) AU637991B2 (de)
CA (1) CA2006356C (de)
DE (1) DE68913487T2 (de)
DK (1) DK169266B1 (de)
ES (1) ES2062050T3 (de)
FI (1) FI93005C (de)
GB (1) GB8830312D0 (de)
IE (1) IE62668B1 (de)
IL (1) IL92990A (de)
NO (1) NO174772C (de)
NZ (1) NZ231855A (de)
PT (1) PT92728B (de)
ZA (1) ZA899960B (de)

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DE4101686A1 (de) 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
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DE4127849A1 (de) * 1991-08-22 1993-02-25 Merck Patent Gmbh Benzodioxanderivate
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FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
ES2050623B1 (es) * 1992-11-06 1994-12-16 Merck Patent Gmbh Derivados de 1,4-benzodioxano.
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CZ295937B6 (cs) * 1997-07-25 2005-12-14 H. Lundbeck A/S Indolové nebo 2,3-dihydroindolové deriváty
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AR022303A1 (es) * 1999-01-22 2002-09-04 Lundbeck & Co As H Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion
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AR027134A1 (es) * 1999-12-30 2003-03-12 Lundbeck & Co As H Derivados de indol.
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EP2464227A4 (de) * 2009-08-10 2013-02-20 Galenea Corp Verbindungen und anwendungsverfahren dafür
CN102993186B (zh) * 2012-12-20 2015-11-18 北京海步国际医药科技发展有限公司 一种新型的哌嗪衍生物
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CN106065018B (zh) * 2015-04-23 2020-04-21 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
CN106243088B (zh) 2015-06-03 2019-01-04 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途

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Also Published As

Publication number Publication date
GB8830312D0 (en) 1989-02-22
FI93005B (fi) 1994-10-31
DE68913487D1 (de) 1994-04-07
DK645689A (da) 1990-06-29
PT92728B (pt) 1995-12-29
DE68913487T2 (de) 1994-08-04
EP0376607B1 (de) 1994-03-02
IL92990A0 (en) 1990-09-17
DK169266B1 (da) 1994-09-26
EP0376607A1 (de) 1990-07-04
JPH02225460A (ja) 1990-09-07
IE62668B1 (en) 1995-02-22
ES2062050T3 (es) 1994-12-16
ZA899960B (en) 1990-11-28
FI93005C (fi) 1995-02-10
NO174772B (no) 1994-03-28
CA2006356A1 (en) 1990-06-28
NO895281L (no) 1990-06-29
NO174772C (no) 1994-07-06
IE893976L (en) 1990-06-13
PT92728A (pt) 1990-06-29
AU4719889A (en) 1990-07-05
DK645689D0 (da) 1989-12-19
NZ231855A (en) 1992-02-25
FI896300A0 (fi) 1989-12-28
AU637991B2 (en) 1993-06-17
JP2895121B2 (ja) 1999-05-24
IL92990A (en) 1995-01-24
CA2006356C (en) 1999-09-14
US5002948A (en) 1991-03-26
NO895281D0 (no) 1989-12-27

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