ATE102953T1 - Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen. - Google Patents

Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen.

Info

Publication number: ATE102953T1
Authority: AT; Austria
Prior art keywords: preparation; analogues; thrymopentin; pharmaceutical compositions; group
Prior art date: 1988-12-23

Application number

AT89203230T

Other languages

English (en)

Inventor

Sabina Mariotti

Alessandro Sisto

Luciano Nencioni

Luigi Villa

Antonio Silvio Verdini

Original Assignee

Sclavo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-23

Filing date

1989-12-18

Publication date

1994-04-15

1989-12-18 Application filed by Sclavo Spa filed Critical Sclavo Spa

1994-04-15 Application granted granted Critical

1994-04-15 Publication of ATE102953T1 publication Critical patent/ATE102953T1/de

Links

238000000034 method Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
PSWFFKRAVBDQEG-YGQNSOCVSA-N thymopentin Chemical class NC(N)=NCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 PSWFFKRAVBDQEG-YGQNSOCVSA-N 0.000 abstract 3
101800001703 Thymopentin Proteins 0.000 abstract 2
102400000160 Thymopentin Human genes 0.000 abstract 2
229960004517 thymopentin Drugs 0.000 abstract 2
239000004215 Carbon black (E152) Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT89203230T 1988-12-23 1989-12-18 Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen. ATE102953T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT8823099A IT1227908B (it)	1988-12-23	1988-12-23	Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
EP89203230A EP0375058B1 (de)	1988-12-23	1989-12-18	Retro-Inverso-Thrymopentin-Analoge, Verfahren zu deren Herstellung und deren Verwendung für die Zubereitung von pharmazeutischen Zusammensetzungen

Publications (1)

Publication Number	Publication Date
ATE102953T1 true ATE102953T1 (de)	1994-04-15

Family

ID=11203770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89203230T ATE102953T1 (de)	1988-12-23	1989-12-18	Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen.

Country Status (8)

Country	Link
US (1)	US5091510A (de)
EP (1)	EP0375058B1 (de)
JP (1)	JPH02247159A (de)
AT (1)	ATE102953T1 (de)
CA (1)	CA2006561A1 (de)
DE (1)	DE68913936T2 (de)
ES (1)	ES2061958T3 (de)
IT (1)	IT1227908B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5218089A (en) *	1988-12-23	1993-06-08	Sclavo S.P.A.	Retro-inverso analogues of thymopentin and the method for their synthesis
RU2210382C1 (ru) *	2002-07-09	2003-08-20	Терентьев Александр Александрович	Пептид, обладающий иммунорегуляторным свойством, и его композиция
EP1840133A1 (de)	2006-03-29	2007-10-03	Global Biotech Development Corp. Ltd.	Neue immunomodulierende Oligopeptide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4505853A (en) *	1983-11-18	1985-03-19	Ortho Pharmaceutical Corporation	Enzyme-resistant immunomodulatory peptides
US4547489A (en) *	1984-06-11	1985-10-15	Ortho Pharmaceutical Corporation	Conformationally restricted thymopentin-like compounds
US4629723A (en) *	1984-06-27	1986-12-16	Ortho Pharmaceutical Corporation	Potent thymopentin analogs
IT1216908B (it) *	1987-03-19	1990-03-14	Eniricerche Spa	Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.

1988
- 1988-12-23 IT IT8823099A patent/IT1227908B/it active
1989
- 1989-12-18 AT AT89203230T patent/ATE102953T1/de not_active IP Right Cessation
- 1989-12-18 ES ES89203230T patent/ES2061958T3/es not_active Expired - Lifetime
- 1989-12-18 DE DE68913936T patent/DE68913936T2/de not_active Expired - Fee Related
- 1989-12-18 EP EP89203230A patent/EP0375058B1/de not_active Expired - Lifetime
- 1989-12-21 US US07/454,282 patent/US5091510A/en not_active Expired - Fee Related
- 1989-12-22 CA CA002006561A patent/CA2006561A1/en not_active Abandoned
- 1989-12-25 JP JP1336183A patent/JPH02247159A/ja active Pending

Also Published As

Publication number	Publication date
JPH02247159A (ja)	1990-10-02
EP0375058A3 (de)	1991-06-12
CA2006561A1 (en)	1990-06-23
DE68913936D1 (de)	1994-04-21
IT8823099A0 (it)	1988-12-23
EP0375058A2 (de)	1990-06-27
IT1227908B (it)	1991-05-14
EP0375058B1 (de)	1994-03-16
DE68913936T2 (de)	1994-07-07
US5091510A (en)	1992-02-25
ES2061958T3 (es)	1994-12-16

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Legal Events

Date	Code	Title	Description
1994-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties