ATE102953T1 - Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen. - Google Patents

Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen.

Info

Publication number
ATE102953T1
ATE102953T1 AT89203230T AT89203230T ATE102953T1 AT E102953 T1 ATE102953 T1 AT E102953T1 AT 89203230 T AT89203230 T AT 89203230T AT 89203230 T AT89203230 T AT 89203230T AT E102953 T1 ATE102953 T1 AT E102953T1
Authority
AT
Austria
Prior art keywords
preparation
analogues
thrymopentin
pharmaceutical compositions
group
Prior art date
Application number
AT89203230T
Other languages
English (en)
Inventor
Sabina Mariotti
Alessandro Sisto
Luciano Nencioni
Luigi Villa
Antonio Silvio Verdini
Original Assignee
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo Spa filed Critical Sclavo Spa
Application granted granted Critical
Publication of ATE102953T1 publication Critical patent/ATE102953T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT89203230T 1988-12-23 1989-12-18 Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen. ATE102953T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8823099A IT1227908B (it) 1988-12-23 1988-12-23 Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
EP89203230A EP0375058B1 (de) 1988-12-23 1989-12-18 Retro-Inverso-Thrymopentin-Analoge, Verfahren zu deren Herstellung und deren Verwendung für die Zubereitung von pharmazeutischen Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE102953T1 true ATE102953T1 (de) 1994-04-15

Family

ID=11203770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89203230T ATE102953T1 (de) 1988-12-23 1989-12-18 Retro-inverso-thrymopentin-analoge, verfahren zu deren herstellung und deren verwendung fuer die zubereitung von pharmazeutischen zusammensetzungen.

Country Status (8)

Country Link
US (1) US5091510A (de)
EP (1) EP0375058B1 (de)
JP (1) JPH02247159A (de)
AT (1) ATE102953T1 (de)
CA (1) CA2006561A1 (de)
DE (1) DE68913936T2 (de)
ES (1) ES2061958T3 (de)
IT (1) IT1227908B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218089A (en) * 1988-12-23 1993-06-08 Sclavo S.P.A. Retro-inverso analogues of thymopentin and the method for their synthesis
RU2210382C1 (ru) * 2002-07-09 2003-08-20 Терентьев Александр Александрович Пептид, обладающий иммунорегуляторным свойством, и его композиция
EP1840133A1 (de) 2006-03-29 2007-10-03 Global Biotech Development Corp. Ltd. Neue immunomodulierende Oligopeptide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
US4547489A (en) * 1984-06-11 1985-10-15 Ortho Pharmaceutical Corporation Conformationally restricted thymopentin-like compounds
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.

Also Published As

Publication number Publication date
EP0375058B1 (de) 1994-03-16
IT1227908B (it) 1991-05-14
JPH02247159A (ja) 1990-10-02
IT8823099A0 (it) 1988-12-23
EP0375058A2 (de) 1990-06-27
US5091510A (en) 1992-02-25
CA2006561A1 (en) 1990-06-23
EP0375058A3 (de) 1991-06-12
DE68913936D1 (de) 1994-04-21
DE68913936T2 (de) 1994-07-07
ES2061958T3 (es) 1994-12-16

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties