ATE102956T1 - Polypeptide und deren derivate und deren verwendung in pharmazeutischen und diagnostischen zusammensetzungen. - Google Patents
Polypeptide und deren derivate und deren verwendung in pharmazeutischen und diagnostischen zusammensetzungen.Info
- Publication number
- ATE102956T1 ATE102956T1 AT88203040T AT88203040T ATE102956T1 AT E102956 T1 ATE102956 T1 AT E102956T1 AT 88203040 T AT88203040 T AT 88203040T AT 88203040 T AT88203040 T AT 88203040T AT E102956 T1 ATE102956 T1 AT E102956T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- sequence
- derivatives
- polypeptide
- amino acid
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 206010071155 Autoimmune arthritis Diseases 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 241001467552 Mycobacterium bovis BCG Species 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8703107A NL8703107A (nl) | 1987-12-22 | 1987-12-22 | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
| EP88203040A EP0322990B1 (de) | 1987-12-22 | 1988-12-21 | Polypeptide und deren Derivate und deren Verwendung in pharmazeutischen und diagnostischen Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE102956T1 true ATE102956T1 (de) | 1994-04-15 |
Family
ID=19851135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88203040T ATE102956T1 (de) | 1987-12-22 | 1988-12-21 | Polypeptide und deren derivate und deren verwendung in pharmazeutischen und diagnostischen zusammensetzungen. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5154923A (de) |
| EP (1) | EP0322990B1 (de) |
| JP (1) | JPH02797A (de) |
| AT (1) | ATE102956T1 (de) |
| AU (1) | AU614004B2 (de) |
| CA (1) | CA1325612C (de) |
| DE (1) | DE3888502D1 (de) |
| DK (1) | DK714788A (de) |
| IL (1) | IL88750A (de) |
| NL (1) | NL8703107A (de) |
| NO (1) | NO885664L (de) |
| ZA (1) | ZA889486B (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4976958A (en) * | 1987-02-26 | 1990-12-11 | Scripps Clinic And Research Foundation | Mycobacterial recombinants and peptides |
| NL8703107A (nl) * | 1987-12-22 | 1989-07-17 | Nederlanden Staat | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
| US5114844A (en) * | 1989-03-14 | 1992-05-19 | Yeda Research And Development Co., Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus |
| GB8919321D0 (en) * | 1989-08-25 | 1989-10-11 | Univ London | Treatment of chronic inflammatory conditions |
| US6897287B1 (en) * | 1990-01-31 | 2005-05-24 | Oklahoma Medical Research Foundation | Ro/SSA peptide reagents for diagnosis of autoantibodies |
| US6232522B1 (en) | 1990-01-31 | 2001-05-15 | Oklahoma Medical Research Foundation | Non-human animal model for systemic lupus erythematosis |
| GB2251186A (en) * | 1990-12-04 | 1992-07-01 | Randall Neal Gatz | Polypeptide for use in treatment of autoimmune disease |
| IL102687A (en) * | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| WO1994003478A1 (en) * | 1992-07-31 | 1994-02-17 | Immulogic Pharmaceutical Corporation | Sensitive assay for antigens and antibodies and its use to identify rheumatoid arthritis antigen |
| WO1994007517A1 (en) | 1992-10-02 | 1994-04-14 | Alberta Research Council | Anti-inflammatory tolerogenic and immunoinhibiting properties of carbohydrate binding-peptides |
| US5453272A (en) * | 1992-10-02 | 1995-09-26 | Alberta Research Council | Lectin derived carbohydrate binding-peptide |
| ATE212378T1 (de) | 1993-06-04 | 2002-02-15 | Whitehead Biomedical Inst | Stressproteine und ihre verwendung |
| ES2313719T3 (es) | 1993-11-23 | 2009-03-01 | The Regents Of The University Of California | Productos extracelulares abundantes y procedimiento de produccion y uso de los mismos. |
| US6752993B1 (en) | 1993-11-23 | 2004-06-22 | The Regents Of The University Of California | Abundant extracellular product vaccines and methods for their production and use |
| US7300660B2 (en) * | 1993-11-23 | 2007-11-27 | The Regents Of The University Of California | Abundant extracellular products and methods for their production and use |
| US7888458B1 (en) * | 1993-11-30 | 2011-02-15 | John B. Harley | Diagnostics and therapy of epstein-barr virus in autoimmune disorders |
| ES2216009T3 (es) * | 1994-03-21 | 2004-10-16 | Rijksuniversiteit Utrecht | Fragmentos peptidicos de proteinas de estres microbianas y composicion farmaceutica a base de estos para el tratamiento y la prevencion de enfermedades inflamatorias. |
| US5869058A (en) * | 1994-05-25 | 1999-02-09 | Yeda Research And Development Co. Ltd. | Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines |
| HU220746B1 (hu) * | 1994-06-17 | 2002-05-28 | Instituut Voor Veehouderij En Diergezondheid | Pestivírustörzsekből izolált nukleotidszekvenciák, az általuk kódolt polipeptidek és ezek alkalmazása pestivírus-fertőzések diagnosztizálására és megelőzésére |
| US5776692A (en) * | 1995-05-23 | 1998-07-07 | Baylor College Of Medicine | Mycobacterial genus-specific DNA probe and its expressed product |
| US5843664A (en) * | 1996-06-11 | 1998-12-01 | Institut Pasteur | Method of selection of allelic exchange mutants |
| US6013660A (en) * | 1996-10-02 | 2000-01-11 | The Regents Of The University Of California | Externally targeted prophylactic and chemotherapeutic method and agents |
| US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| US7273613B1 (en) | 1997-01-13 | 2007-09-25 | The Board of Regents, The University of Oklahoma | Diagnostics and therapy of Epstein-Barr virus in autoimmune disorders |
| ATE231917T1 (de) | 1997-08-05 | 2003-02-15 | Stressgen Biotechnologies Corp | Immunresponse gegen hpv antigene erregt von zusammensetzungen die ein hpv antigen und ein stressprotein enthalten oder einen expressionsvektor fähig zur expression dieser proteine |
| US6007821A (en) * | 1997-10-16 | 1999-12-28 | Fordham University | Method and compositions for the treatment of autoimmune disease using heat shock proteins |
| EP0947524A1 (de) * | 1998-03-30 | 1999-10-06 | Upither B.V. | Neue Peptide zur Behandlung von Autoimmunkrankheiten |
| US6497880B1 (en) | 1998-12-08 | 2002-12-24 | Stressgen Biotechnologies Corporation | Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus |
| US6638518B1 (en) | 1999-02-22 | 2003-10-28 | University Of Iowa Research Foundation | Method for inhibiting inflammatory responses |
| EP1196772A2 (de) | 1999-07-08 | 2002-04-17 | Stressgen Biotechnologies Corporation | Induktion einer th1-vermittelten immunantwort in vitro |
| AU1814101A (en) | 2000-01-14 | 2001-07-24 | Massachusetts Institute Of Technology | In vivo CTL elicitation by heat shock protein fusion proteins maps to a discrete ATP binding domain and is CD4+ cell-independent |
| US6812205B2 (en) | 2000-03-15 | 2004-11-02 | The Brigham & Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
| IL153474A0 (en) | 2000-06-26 | 2003-07-06 | Stressgen Biotechnologies Corp | Human papilloma virus treatment |
| WO2002062959A2 (en) | 2001-02-05 | 2002-08-15 | Stressgen Biotechnologies Corp. | Hepatitis b virus treatment |
| EP1386155A4 (de) * | 2001-04-10 | 2006-05-10 | Univ Leland Stanford Junior | Therapeutische und diagnostische verwendungen von antikörperspezifitätsprofilen |
| AU2003230181A1 (en) | 2002-05-21 | 2003-12-02 | Yeda Research And Development Co. Ltd. | Dna vaccines encoding heat shock proteins |
| US20060142251A1 (en) * | 2002-11-15 | 2006-06-29 | Gunther Harth | Anti-microbial agents derived from methionine sulfoximine analogues |
| US20050137156A1 (en) * | 2003-08-09 | 2005-06-23 | Johnston Stephen A. | Methods and compositions for generating an immune response |
| US8389694B2 (en) * | 2003-11-25 | 2013-03-05 | Amanda L. Blasius | Biologically active antibodies recognizing a cell surface molecule selectively expressed on living mouse natural type one (I) interferon producing cells |
| KR20050056799A (ko) * | 2003-12-10 | 2005-06-16 | 엘지.필립스 엘시디 주식회사 | 액정 표시패널의 실 패턴 구조 |
| CU23504A1 (es) | 2004-09-24 | 2010-04-13 | Ct Ingenieria Genetica Biotech | Péptidos y derivados tipo apl de la hsp60 y composiciones farmacéuticas |
| EP1835933A4 (de) | 2005-01-04 | 2015-01-07 | Yeda Res & Dev | Hsp60, hsp60-peptide und t-zellen-impfstoffe zur immunmodulation |
| CA2601518A1 (en) * | 2005-03-14 | 2006-09-21 | Irun R. Cohen | Compositions of hsp60 peptides and viral antigens for vaccination and diagnosis |
| EP2007427A4 (de) | 2006-04-11 | 2012-04-04 | Yeda Res & Dev | Verbesserte impfstoffe mit multimeren hsp60-peptid-trägern |
| JP2008189637A (ja) | 2007-02-08 | 2008-08-21 | Snow Brand Milk Prod Co Ltd | 自己免疫疾患予防剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2487198A1 (fr) * | 1980-07-28 | 1982-01-29 | Berri Balzac Sa | Nouvelle substance immuno-suppressive, son procede d'isolement et son application en therapeutique |
| IL71683A0 (en) * | 1984-04-27 | 1984-09-30 | Yeda Res & Dev | Pharmaceutical compositions for treating arthritis type diseases comprising fractions obtained from mycobacteria |
| GB8508685D0 (en) * | 1985-04-03 | 1985-05-09 | Minor P D | Peptides |
| US4689397A (en) * | 1985-08-12 | 1987-08-25 | Scripps Clinic And Research Foundation | Synthetic polypeptides for detecting mycobacterial infections |
| US4772685A (en) * | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
| US4777239A (en) * | 1986-07-10 | 1988-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic peptides of human papilloma virus |
| NL8701163A (nl) * | 1986-09-09 | 1988-04-05 | Nederlanden Staat | Gebruik van een peptide voor de bereiding van preparaten voor het verlichten, het behandelen en de diagnose van autoimmuunziekten, in het bijzonder arthritische toestanden, verbindingen die met dit peptide verwant zijn, alsmede farmaceutische en diagnostische preparaten en testkits. |
| US4952395A (en) * | 1987-02-26 | 1990-08-28 | Scripps Clinic And Research Foundation | Mycobacterial recombinants and peptides |
| NL8703107A (nl) * | 1987-12-22 | 1989-07-17 | Nederlanden Staat | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
-
1987
- 1987-12-22 NL NL8703107A patent/NL8703107A/nl not_active Application Discontinuation
-
1988
- 1988-12-20 ZA ZA889486A patent/ZA889486B/xx unknown
- 1988-12-21 US US07/288,080 patent/US5154923A/en not_active Expired - Fee Related
- 1988-12-21 CA CA000586746A patent/CA1325612C/en not_active Expired - Fee Related
- 1988-12-21 EP EP88203040A patent/EP0322990B1/de not_active Expired - Lifetime
- 1988-12-21 NO NO88885664A patent/NO885664L/no unknown
- 1988-12-21 DE DE88203040T patent/DE3888502D1/de not_active Expired - Lifetime
- 1988-12-21 AT AT88203040T patent/ATE102956T1/de not_active IP Right Cessation
- 1988-12-21 DK DK714788A patent/DK714788A/da not_active Application Discontinuation
- 1988-12-21 AU AU27327/88A patent/AU614004B2/en not_active Ceased
- 1988-12-21 IL IL8875088A patent/IL88750A/en not_active IP Right Cessation
- 1988-12-22 JP JP63324731A patent/JPH02797A/ja active Pending
-
1992
- 1992-06-05 US US07/893,783 patent/US5354691A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0322990A1 (de) | 1989-07-05 |
| DK714788D0 (da) | 1988-12-21 |
| IL88750A (en) | 1994-01-25 |
| AU2732788A (en) | 1989-06-22 |
| AU614004B2 (en) | 1991-08-15 |
| DK714788A (da) | 1989-06-23 |
| US5154923A (en) | 1992-10-13 |
| CA1325612C (en) | 1993-12-28 |
| JPH02797A (ja) | 1990-01-05 |
| ZA889486B (en) | 1989-09-27 |
| NL8703107A (nl) | 1989-07-17 |
| NO885664L (no) | 1989-06-23 |
| DE3888502D1 (de) | 1994-04-21 |
| NO885664D0 (no) | 1988-12-21 |
| US5354691A (en) | 1994-10-11 |
| EP0322990B1 (de) | 1994-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |