ATE103176T1 - Gepufferte metronidazolmittel zur intravaginalen behandlung vaginaler infektionen. - Google Patents

Gepufferte metronidazolmittel zur intravaginalen behandlung vaginaler infektionen.

Info

Publication number
ATE103176T1
ATE103176T1 AT90306026T AT90306026T ATE103176T1 AT E103176 T1 ATE103176 T1 AT E103176T1 AT 90306026 T AT90306026 T AT 90306026T AT 90306026 T AT90306026 T AT 90306026T AT E103176 T1 ATE103176 T1 AT E103176T1
Authority
AT
Austria
Prior art keywords
metronidazole
agent
vaginal infections
buffered
composition
Prior art date
Application number
AT90306026T
Other languages
English (en)
Inventor
Robert J Borgman
Original Assignee
Curatek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curatek Pharmaceuticals filed Critical Curatek Pharmaceuticals
Application granted granted Critical
Publication of ATE103176T1 publication Critical patent/ATE103176T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90306026T 1989-06-06 1990-06-05 Gepufferte metronidazolmittel zur intravaginalen behandlung vaginaler infektionen. ATE103176T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36227389A 1989-06-06 1989-06-06

Publications (1)

Publication Number Publication Date
ATE103176T1 true ATE103176T1 (de) 1994-04-15

Family

ID=23425444

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90306026T ATE103176T1 (de) 1989-06-06 1990-06-05 Gepufferte metronidazolmittel zur intravaginalen behandlung vaginaler infektionen.

Country Status (21)

Country Link
EP (1) EP0404376B1 (de)
JP (1) JP2999820B2 (de)
KR (1) KR0169487B1 (de)
CN (1) CN1054507C (de)
AT (1) ATE103176T1 (de)
AU (1) AU635752B2 (de)
BR (1) BR9006793A (de)
CA (1) CA1337279C (de)
DE (1) DE69007547T2 (de)
DK (1) DK0404376T3 (de)
ES (1) ES2062366T3 (de)
HU (1) HU207795B (de)
IE (1) IE65413B1 (de)
IL (1) IL94619A (de)
PH (1) PH30718A (de)
PL (1) PL164128B1 (de)
RO (1) RO109156B1 (de)
RU (1) RU2032402C1 (de)
WO (1) WO1990014832A1 (de)
YU (1) YU47950B (de)
ZA (1) ZA904413B (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5592949A (en) * 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
GB9610359D0 (en) * 1996-05-17 1996-07-24 Edko Trading Representation Pharmaceutical compositions
GB9626513D0 (en) * 1996-12-20 1997-02-05 Bioglan Ireland R & D Ltd A pharmaceutical composition
RU2154477C1 (ru) * 1998-12-10 2000-08-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения хронического трихомониаза
RU2195945C2 (ru) * 2000-02-14 2003-01-10 Владивостокский государственный медицинский университет Способ лечения инфекций, передаваемых половым путем
RU2195943C2 (ru) * 2000-02-14 2003-01-10 Владивостокский государственный медицинский университет Способ лечения гонореи
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
IL157771A0 (en) * 2001-03-27 2004-03-28 Galen Chemicals Ltd Intravaginal drug delivery devices for the administration of an antimicrobial agent
RU2180567C1 (ru) * 2001-05-03 2002-03-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения хронического рецидивирующего трихомониаза
RU2212238C2 (ru) * 2001-11-05 2003-09-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения рецидивирующего урогенитального кандидоза на фоне трихомониаза
GB0130666D0 (en) * 2001-12-21 2002-02-06 Accantla Holdings Ltd Absorbent tampons
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
RU2221574C2 (ru) * 2002-03-21 2004-01-20 Саратовский государственный медицинский университет Способ лечения хронического трихомонадного эндоцервицита
MXPA04010890A (es) * 2002-05-01 2005-07-14 Johnson & Johnson Composiciones lubricantes anhidras generadoras de calor y no irritantes.
US7658941B2 (en) 2002-05-01 2010-02-09 Johnson & Johnson Consumer Companies, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
CA2484318C (en) * 2002-05-01 2014-01-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant antifungal gel compositions
US7695730B2 (en) 2002-05-01 2010-04-13 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7005408B2 (en) * 2002-05-01 2006-02-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7417013B2 (en) 2002-05-01 2008-08-26 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US20060140984A1 (en) 2002-10-25 2006-06-29 Foamix Ltd. Cosmetic and pharmaceutical foam
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
RU2240781C1 (ru) * 2003-06-05 2004-11-27 Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии Способ лечения воспалительных процессов вульвы и влагалища
EP1635847B1 (de) * 2003-06-13 2019-07-31 IDH Holding ApS Behandlung von symptomen im zusammenhang mit bakterieller vaginose
RU2236851C1 (ru) * 2003-06-16 2004-09-27 Красноярская государственная медицинская академия Способ местного лечения бактериального вагиноза
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
WO2005027807A1 (en) 2003-09-19 2005-03-31 Drugtech Corporation Pharmaceutical delivery system
RU2249821C1 (ru) * 2004-04-27 2005-04-10 Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского Министерства здравоохранения Российской Федерации" Способ оценки микробиоценоза влагалища
MXPA04007681A (es) * 2004-07-08 2006-01-12 Drugtech Corp Sistema de liberacion.
RU2275918C1 (ru) * 2005-01-11 2006-05-10 ГОУ ВПО "Красноярская государственная медицинская академия Министерства здравоохранения РФ" Способ лечения хронического сальпингоофорита
US7851419B2 (en) 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
US20070059250A1 (en) * 2005-09-12 2007-03-15 Nawaz Ahmad Sprayable personal lubricant
WO2007079389A2 (en) * 2006-01-05 2007-07-12 Drugtech Corporation Composition and method of use thereof
KR20080083190A (ko) * 2006-01-05 2008-09-16 드러그테크 코포레이션 외음질 표면에 생체접착을 위한 약물 전달 시스템
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
RU2356535C2 (ru) * 2007-07-23 2009-05-27 Закрытое Акционерное Общество "Биокад" Суппозитории комбинированного действия для лечения инфекционных гинекологических заболеваний (варианты)
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
AU2009205314A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
EP2385821B1 (de) * 2009-01-09 2016-08-31 Egis Gyógyszergyár Zrt. Verbesserte pharmazeutische formulierung
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
AU2010302350B2 (en) 2009-10-02 2015-06-18 Journey Medical Corporation Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US12661407B2 (en) 2010-04-08 2026-06-23 Journey Medical Corporation Compositions, gels and foams with rheology modulators and uses thereof
RU2428173C1 (ru) * 2010-06-03 2011-09-10 Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") Фармацевтическая композиция для лечения заболеваний нижнего отдела мочеполовой системы
AU2012275292B2 (en) 2011-06-28 2015-11-12 Chemo Research, S.L. High dosage mucoadhesive metronidazole aqueous-based gel formulations their use to treat bacterial vaginosis
EP3013368A1 (de) 2013-06-25 2016-05-04 Mission Pharmacal Company Neuartige formulierungen zur behandlung von vaginalen erkrankungen
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
RU2730021C1 (ru) * 2019-10-08 2020-08-14 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Средство местного применения для лечения инфекционных вагинитов
CN112773780A (zh) * 2019-11-11 2021-05-11 深圳优丽康生物技术有限公司 一种阴道外阴用组合物及其用途
RU2726123C1 (ru) * 2019-12-20 2020-07-09 Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук Способ лечения трихомониаза у женщин
US11529346B2 (en) * 2020-06-18 2022-12-20 National Medical Supply, LLC Vaginal gel
US20210401879A1 (en) * 2020-06-30 2021-12-30 Vireo Systems, Inc. Compositions for controlling odor and itch and methods of and devices for administering same
CN115737551B (zh) * 2022-12-06 2025-08-05 天津市保灵动物保健品有限公司 一种氟苯尼考甲硝唑滴耳液及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3070778D1 (en) * 1979-08-11 1985-07-25 Bayer Ag Antimycotic agents with enhanced release of the active ingredients
US4602040A (en) * 1983-04-18 1986-07-22 Warner-Lambert Company Meclofenamic acid topical pharmaceutical composition
US4837378A (en) * 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
GB8607159D0 (en) * 1986-03-22 1986-04-30 Smith & Nephew Ass Pharmaceutical composition
SE8603338D0 (sv) * 1986-08-07 1986-08-07 Bjorn Andersch Medel for behandling av tillstand i slidan

Also Published As

Publication number Publication date
HUT56490A (en) 1991-09-30
DE69007547T2 (de) 1994-07-14
CN1054507C (zh) 2000-07-19
HU904720D0 (en) 1991-07-29
YU47950B (sh) 1996-07-24
YU170090A (sh) 1994-04-05
CN1049101A (zh) 1991-02-13
KR920700032A (ko) 1992-02-19
ZA904413B (en) 1991-04-24
JPH04500365A (ja) 1992-01-23
AU5829490A (en) 1991-01-07
RO109156B1 (ro) 1994-12-30
KR0169487B1 (ko) 1999-01-15
IL94619A0 (en) 1991-04-15
EP0404376A3 (de) 1991-06-05
BR9006793A (pt) 1991-08-06
RU2032402C1 (ru) 1995-04-10
EP0404376A2 (de) 1990-12-27
CA1337279C (en) 1995-10-10
ES2062366T3 (es) 1994-12-16
AU635752B2 (en) 1993-04-01
EP0404376B1 (de) 1994-03-23
DK0404376T3 (da) 1994-05-24
WO1990014832A1 (en) 1990-12-13
PL164128B1 (pl) 1994-06-30
IE65413B1 (en) 1995-10-18
IE902011L (en) 1990-12-06
HU207795B (en) 1993-06-28
PH30718A (en) 1997-09-23
PL285507A1 (en) 1992-01-13
DE69007547D1 (de) 1994-04-28
IL94619A (en) 1995-01-24
JP2999820B2 (ja) 2000-01-17

Similar Documents

Publication Publication Date Title
DE69007547D1 (de) Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen.
US5905092A (en) Topical antibiotic composition providing optimal moisture environment for rapid wound healing that reduces skin contraction
CN113999406A (zh) 一种多功能抗菌水凝胶敷料的制备方法及应用
IE812025L (en) Composition for treating osteitis
EP0266968A3 (de) Gelierte Salbe mit einem Vasodilator
DE69739792D1 (de) Verfahren zur Behandlung von Augenerkrankungen
WO2000056353A3 (en) A uro-genital condition treatment system
SE8803087L (sv) Ett nytt saett foer behandling av erektil dysfunktion
CA2159730A1 (en) Ionene polymers as anthelmintics in animals
KR900012617A (ko) 혈전증 치료제 및 그 제조방법
KR970705392A (ko) 신규한 항생제 조성물 및 그람-양성 세균 및 마이코플라스마 감염의 치료 방법(novel antibiotic compounds and methods to treat grampositive bacterial and mycoplasmal infections)
FR2542616B1 (fr) Composition pour le traitement des muqueuses a base d'un antibiotique et d'un hydrocolloide formateur de gel
RU2000108461A (ru) Вакцина против урогенитальных инфекций на основе вагинального суппозитория
EP0305744A3 (de) Chinolin-, Naphthyridin- und Benzoxazincarbonsäure-Derivate und ihre Verwendung als antibakterielle Mittel
ATE202924T1 (de) Augentropfen insbesonders zur behandlung des trockenen auges
HU901897D0 (en) Process for producing medical preparations suitable for treating vaginal infection
SU1690767A1 (ru) Способ лечени гнойных ран
GB1538932A (en) Therapeutic method of treating mink infection and bovine mastitis by pseudomonas aeruginosa
RU2180241C2 (ru) Ранозаживляющее средство
Suter et al. Prophylactic antibiotics for hysterectomy
EP0987019A1 (de) Topisches Antibiotikum zur raschen Wundheilung
RU96114051A (ru) Способ лечения экземы у травматолого-ортопедических больных с гнойной инфекцией
UA33121A (uk) Спосіб лікування маститу у корів
UA13697A1 (uk) Спосіб передпосівhої обробки hасіhhя

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time