ATE105556T1 - Benzopyranverbindungen, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen. - Google Patents
Benzopyranverbindungen, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen.Info
- Publication number
- ATE105556T1 ATE105556T1 AT9090115242T AT90115242T ATE105556T1 AT E105556 T1 ATE105556 T1 AT E105556T1 AT 9090115242 T AT9090115242 T AT 9090115242T AT 90115242 T AT90115242 T AT 90115242T AT E105556 T1 ATE105556 T1 AT E105556T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- alkyl
- substituted
- hydrogen atom
- preparation
- Prior art date
Links
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000006518 morpholino carbonyl group Chemical group [H]C1([H])OC([H])([H])C([H])([H])N(C(*)=O)C1([H])[H] 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20854789 | 1989-08-11 | ||
| JP34152889 | 1989-12-29 | ||
| JP7365490 | 1990-03-23 | ||
| JP7365390 | 1990-03-23 | ||
| EP90115242A EP0412531B1 (de) | 1989-08-11 | 1990-08-08 | Benzopyranverbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE105556T1 true ATE105556T1 (de) | 1994-05-15 |
Family
ID=27465604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT9090115242T ATE105556T1 (de) | 1989-08-11 | 1990-08-08 | Benzopyranverbindungen, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5095016A (de) |
| EP (1) | EP0412531B1 (de) |
| KR (1) | KR910004592A (de) |
| CN (1) | CN1049500A (de) |
| AT (1) | ATE105556T1 (de) |
| AU (1) | AU624526B2 (de) |
| CA (1) | CA2022882A1 (de) |
| CZ (1) | CZ393390A3 (de) |
| DE (1) | DE69008791T2 (de) |
| FI (1) | FI903939A7 (de) |
| HU (1) | HUT54673A (de) |
| NO (1) | NO174050C (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5140031A (en) * | 1989-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Pyranyl cyanoguanidine derivatives |
| US5061813A (en) * | 1990-04-02 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Substituted cyanoimino benzopyranes |
| US5276168A (en) * | 1990-06-18 | 1994-01-04 | E. R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
| JPH05186458A (ja) * | 1991-04-26 | 1993-07-27 | Japan Tobacco Inc | 新規なベンゾピラン誘導体 |
| US5374643A (en) * | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
| US5453421A (en) * | 1992-09-11 | 1995-09-26 | E. R. Squibb & Sons, Inc. | Aryl and heterocyclic substituted propenamide derivatives |
| US5514690A (en) * | 1992-11-17 | 1996-05-07 | E. R. Squibb & Sons, Inc. | Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline |
| IL109229A0 (en) * | 1993-05-11 | 1994-07-31 | Bristol Myers Squibb Co | Heterocyclic compounds and processes for the preparation of pyranyl cyanoguanidine derivatives using the same |
| US5393771A (en) * | 1993-05-12 | 1995-02-28 | Brisol-Myers Squibb Company | 4-substituted benzopyran and related compounds |
| US5837702A (en) * | 1993-10-07 | 1998-11-17 | Bristol-Myers Squibb Co. | 4-arylamino-benzopyran and related compounds |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| US5547966A (en) * | 1993-10-07 | 1996-08-20 | Bristol-Myers Squibb Company | Aryl urea and related compounds |
| US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
| US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
| US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
| US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
| DE19921886A1 (de) * | 1999-05-12 | 2000-11-16 | Bayer Ag | Substituierte N-Cyano-amidine |
| EP1401823B1 (de) * | 2001-06-25 | 2005-10-05 | Nissan Chemical Industries, Ltd. | Substituierte benzopyran derivate gegen arrhythmie |
| WO2003014113A1 (en) * | 2001-08-06 | 2003-02-20 | Glenmark Pharmaceuticals Limited | Novel benzopyran compounds and process for their preparation and use |
| KR100439972B1 (ko) * | 2002-02-19 | 2004-07-14 | 주식회사 심바이오테인 | 공생과 먹이사슬관계를 이용한 수산생물의 육상생산시설 |
| KR100458861B1 (ko) * | 2002-11-07 | 2004-12-03 | 주식회사 심바이오테인 | 미세조류-어류 공생 생산공장 |
| US7241776B2 (en) * | 2004-08-02 | 2007-07-10 | Abbott Laboratories | Cyanoamidine P2X7 antagonists for the treatment of pain |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419515D0 (en) * | 1984-07-31 | 1984-09-05 | Beecham Group Plc | Treatment |
| GB8521857D0 (en) * | 1985-09-03 | 1985-10-09 | Beecham Group Plc | Active compounds |
| IL84809A (en) * | 1987-11-06 | 1992-12-01 | Ciba Geigy | Process for the synthesis of 1-substituted imidazole- 5-carboxylic acids and derivatives thereof |
| EP0373204A1 (de) * | 1988-05-09 | 1990-06-20 | Beecham Group Plc | Verbindungen und behandlung |
| US4988723A (en) * | 1988-06-02 | 1991-01-29 | Fujisawa Pharmaceutical Co., Ltd. | Benzopyran derivatives and their use as anti-hypertensives |
| GB8902118D0 (en) * | 1989-02-01 | 1989-03-22 | Beecham Group Plc | Chemical process |
-
1990
- 1990-08-03 US US07/562,577 patent/US5095016A/en not_active Expired - Fee Related
- 1990-08-08 EP EP90115242A patent/EP0412531B1/de not_active Expired - Lifetime
- 1990-08-08 DE DE69008791T patent/DE69008791T2/de not_active Expired - Fee Related
- 1990-08-08 CA CA002022882A patent/CA2022882A1/en not_active Abandoned
- 1990-08-08 AT AT9090115242T patent/ATE105556T1/de not_active IP Right Cessation
- 1990-08-09 CZ CS903933A patent/CZ393390A3/cs unknown
- 1990-08-09 FI FI903939A patent/FI903939A7/fi not_active IP Right Cessation
- 1990-08-09 AU AU60844/90A patent/AU624526B2/en not_active Ceased
- 1990-08-10 HU HU904956A patent/HUT54673A/hu unknown
- 1990-08-10 NO NO903524A patent/NO174050C/no unknown
- 1990-08-11 KR KR1019900012382A patent/KR910004592A/ko not_active Withdrawn
- 1990-08-11 CN CN90107121A patent/CN1049500A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU624526B2 (en) | 1992-06-11 |
| EP0412531B1 (de) | 1994-05-11 |
| NO174050B (no) | 1993-11-29 |
| NO903524L (no) | 1991-02-12 |
| DE69008791T2 (de) | 1995-01-12 |
| DE69008791D1 (de) | 1994-06-16 |
| EP0412531A1 (de) | 1991-02-13 |
| CA2022882A1 (en) | 1991-02-12 |
| AU6084490A (en) | 1991-02-14 |
| NO903524D0 (no) | 1990-08-10 |
| NO174050C (no) | 1994-03-09 |
| KR910004592A (ko) | 1991-03-29 |
| CZ393390A3 (en) | 1997-02-12 |
| HU904956D0 (en) | 1991-01-28 |
| FI903939A0 (fi) | 1990-08-09 |
| HUT54673A (en) | 1991-03-28 |
| US5095016A (en) | 1992-03-10 |
| CN1049500A (zh) | 1991-02-27 |
| FI903939A7 (fi) | 1991-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |