ATE105841T1 - 5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen. - Google Patents

5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen.

Info

Publication number: ATE105841T1
Authority: AT; Austria
Prior art keywords: aminosalicylic acid; acid derivatives; pct; therapy; chronic inflammatory
Prior art date: 1990-09-12

Application number

AT91916335T

Other languages

English (en)

Inventor

Roberto Pellicciari

Aaron Garzon

Carlo Clerici

Camillo Maria Francesc Palazzi

Original Assignee

Depha Team Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-12

Filing date

1991-09-10

Publication date

1994-06-15

1991-09-10 Application filed by Depha Team Srl filed Critical Depha Team Srl

1994-06-15 Application granted granted Critical

1994-06-15 Publication of ATE105841T1 publication Critical patent/ATE105841T1/de

Links

KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical class NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 title abstract 3
230000003187 abdominal effect Effects 0.000 title 1
230000001684 chronic effect Effects 0.000 title 1
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
230000002757 inflammatory effect Effects 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
235000003704 aspartic acid Nutrition 0.000 abstract 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
235000013922 glutamic acid Nutrition 0.000 abstract 1
229960004963 mesalazine Drugs 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Crystallography & Structural Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT91916335T 1990-09-12 1991-09-10 5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen. ATE105841T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT02144390A IT1244873B (it)	1990-09-12	1990-09-12	Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali

Publications (1)

Publication Number	Publication Date
ATE105841T1 true ATE105841T1 (de)	1994-06-15

Family

ID=11181864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91916335T ATE105841T1 (de)	1990-09-12	1991-09-10	5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen.

Country Status (11)

Country	Link
US (1)	US5424292A (de)
EP (1)	EP0548177B1 (de)
JP (1)	JPH06500787A (de)
AT (1)	ATE105841T1 (de)
AU (1)	AU8530891A (de)
CA (1)	CA2091459A1 (de)
DE (1)	DE69102069T2 (de)
DK (1)	DK0548177T3 (de)
ES (1)	ES2052391T3 (de)
IT (1)	IT1244873B (de)
WO (1)	WO1992004369A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5484605A (en) *	1988-11-25	1996-01-16	Henning Berlin Gmbh Chemie-Und Pharmawerk	Agent for treating chronically inflammatory intestinal diseases
JP2002512625A (ja) *	1997-05-29	2002-04-23	メルクエンドカンパニーインコーポレーテッド	細胞接着阻害薬としての複素環アミド化合物
US6903075B1 (en)	1997-05-29	2005-06-07	Merck & Co., Inc.	Heterocyclic amide compounds as cell adhesion inhibitors
US6716452B1 (en) *	2000-08-22	2004-04-06	New River Pharmaceuticals Inc.	Active agent delivery systems and methods for protecting and administering active agents
US8394813B2 (en)	2000-11-14	2013-03-12	Shire Llc	Active agent delivery systems and methods for protecting and administering active agents
US20060014697A1 (en) *	2001-08-22	2006-01-19	Travis Mickle	Pharmaceutical compositions for prevention of overdose or abuse
US7169752B2 (en) *	2003-09-30	2007-01-30	New River Pharmaceuticals Inc.	Compounds and compositions for prevention of overdose of oxycodone
NZ544162A (en) *	2003-05-29	2008-09-26	Shire Llc	Abuse resistant amphetamine compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7008623A (de) *	1969-06-25	1970-12-29
NL7008620A (de) *	1969-06-25	1970-12-29
JPS5569549A (en) *	1978-11-16	1980-05-26	Nitto Boseki Co Ltd	Novel substrate for determination of enzyme activity
WO1981002672A1 (en) *	1980-03-20	1981-10-01	Ferring Farma Lab	Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease
US4505898A (en) *	1982-04-21	1985-03-19	Marks Robert E	Derivatives of acetylsalicylic acid and substituted phenylacetic acids and compositions containing them
IT1196348B (it) *	1984-11-29	1988-11-16	Italfarmaco Spa	Composti ad attivita'antiinfiammatoria
US5120306A (en) *	1990-03-21	1992-06-09	Gosselin Leon F	Direct delivery of anti-inflammatories to the proximal small bowel

1990
- 1990-09-12 IT IT02144390A patent/IT1244873B/it active IP Right Grant
1991
- 1991-09-10 WO PCT/EP1991/001718 patent/WO1992004369A1/en not_active Ceased
- 1991-09-10 US US07/984,575 patent/US5424292A/en not_active Expired - Fee Related
- 1991-09-10 DK DK91916335.2T patent/DK0548177T3/da active
- 1991-09-10 AU AU85308/91A patent/AU8530891A/en not_active Abandoned
- 1991-09-10 ES ES91916335T patent/ES2052391T3/es not_active Expired - Lifetime
- 1991-09-10 AT AT91916335T patent/ATE105841T1/de not_active IP Right Cessation
- 1991-09-10 JP JP3515457A patent/JPH06500787A/ja active Pending
- 1991-09-10 EP EP91916335A patent/EP0548177B1/de not_active Expired - Lifetime
- 1991-09-10 CA CA002091459A patent/CA2091459A1/en not_active Abandoned
- 1991-09-10 DE DE69102069T patent/DE69102069T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU8530891A (en)	1992-03-30
EP0548177A1 (de)	1993-06-30
US5424292A (en)	1995-06-13
CA2091459A1 (en)	1992-03-13
EP0548177B1 (de)	1994-05-18
JPH06500787A (ja)	1994-01-27
DK0548177T3 (da)	1994-08-22
DE69102069D1 (de)	1994-06-23
DE69102069T2 (de)	1994-09-01
IT9021443A1 (it)	1992-03-12
IT9021443A0 (it)	1990-09-12
WO1992004369A1 (en)	1992-03-19
IT1244873B (it)	1994-09-12
ES2052391T3 (es)	1994-07-01

Legal Events

Date	Code	Title	Description
1994-12-15	UEP	Publication of translation of european patent specification
2004-06-15	REN	Ceased due to non-payment of the annual fee

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DE69532760D1 (de)	2004-04-29	Mittel zur verabreichung von antigenen
DK1025124T3 (da)	2008-10-06	Human interferon-alfa-analoge med lav toksicitet
DE69731373D1 (de)	2004-12-02	Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
NO981436D0 (no)	1998-03-30	Farmasöytiske angiostatiske dipeptidsammensetninger og anvendelse derav
DK0975761T3 (da)	2004-02-16	Humant, rekombinant beta-interferon med forbedret opløselighed
DK0770089T3 (da)	2000-10-23	Vækstdifferentieringsfaktor-12
NO940299L (no)	1994-01-28	Peptid med organbeskyttende aktivitet
CA2123315A1 (en)	1993-05-27	Therapeutic agents which are antagonists or partial agonists of human interleukin 4
ATE105841T1 (de)	1994-06-15	5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen.
DK0688226T3 (da)	1999-10-11	Proteinpræparat til forebyggelse og terapi af periodontitis eller andre bakterielle patologier i mundhulen
ES548052A0 (es)	1987-02-16	Procedimiento para preparar peptidos
BG97123A (bg)	1993-12-24	Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
DK1431391T3 (da)	2005-12-19	RANTES-mutanter og terapeutiske anvendelser heraf
BG104801A (en)	2001-04-30	Indole-2,3-dione-3-oxime derivatives for therapeutical use
ES2135398T3 (es)	1999-11-01	Compuesto y composiciones de inhibicion de la resorcion osea.
ES2039402T3 (es)	1993-10-01	Empleo de peptidos n,n'-bis-l-aminoacido-l-cistina en preparados de aminoacidos para alimentacion oral y parenteral.
NO894720D0 (no)	1989-11-27	Farmasoeytisk aktivt protein.
GB2262528B (en)	1995-08-16	Further improvements relating to the radiolabelling of proteins
MX9205978A (es)	1993-04-01	Nuevas proteinas inhibidoras de trombina de garrapatas.
ES2109373T3 (es)	1998-01-16	Nueva proteina inhibidora de trombina a partir de garrapatas.
MX9702895A (es)	1997-07-31	Composiciones para el suministro de antigenos.