ATE105855T1 - Ein dns-resistenzgen gegen pyrimidine analoge und dessen verwendung. - Google Patents

Ein dns-resistenzgen gegen pyrimidine analoge und dessen verwendung.

Info

Publication number: ATE105855T1
Authority: AT; Austria
Prior art keywords: dna; resistance gene; pyrimidine analogues; uridine; plasmid
Prior art date: 1988-02-17

Application number

AT89102479T

Other languages

English (en)

Inventor

Satoru Asahi

Yutaka Tsunemi

Muneharu Doi

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-17

Filing date

1989-02-14

Publication date

1994-06-15

1989-02-14 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1994-06-15 Application granted granted Critical

1994-06-15 Publication of ATE105855T1 publication Critical patent/ATE105855T1/de

Links

229940045688 antineoplastic antimetabolites pyrimidine analogues Drugs 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 abstract 4
DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 abstract 4
241000193830 Bacillus <bacterium> Species 0.000 abstract 2
DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 abstract 2
244000005700 microbiome Species 0.000 abstract 2
239000013612 plasmid Substances 0.000 abstract 2
150000003230 pyrimidines Chemical class 0.000 abstract 2
229940035893 uracil Drugs 0.000 abstract 2
DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 abstract 2
229940045145 uridine Drugs 0.000 abstract 2
241000588722 Escherichia Species 0.000 abstract 1
210000000349 chromosome Anatomy 0.000 abstract 1
239000001963 growth medium Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/385—Pyrimidine nucleosides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)

AT89102479T 1988-02-17 1989-02-14 Ein dns-resistenzgen gegen pyrimidine analoge und dessen verwendung. ATE105855T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP3639888		1988-02-17

Publications (1)

Publication Number	Publication Date
ATE105855T1 true ATE105855T1 (de)	1994-06-15

Family

ID=12468747

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89102479T ATE105855T1 (de)	1988-02-17	1989-02-14	Ein dns-resistenzgen gegen pyrimidine analoge und dessen verwendung.

Country Status (7)

Country	Link
EP (1)	EP0329062B1 (de)
JP (1)	JPH022349A (de)
KR (1)	KR890013180A (de)
CN (1)	CN1035129A (de)
AT (1)	ATE105855T1 (de)
DE (1)	DE68915301T2 (de)
ES (1)	ES2052789T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5213972A (en) *	1989-12-08	1993-05-25	Chemgen Corporation	Fermentation process for the production of pyrimidine deoxyribonucleosides
JPH044881A (ja) *	1990-04-23	1992-01-09	Takeda Chem Ind Ltd	シチジンアナログ耐性化遺伝子ｄｎａおよびその用途
ZA923641B (en) *	1991-05-21	1993-02-24	Iaf Biochem Int	Processes for the diastereoselective synthesis of nucleosides
EP1806405A3 (de) *	1999-07-01	2007-10-03	Glaxo Group Limited	Vektoren, Zellen und Verfahren zur Herstellung pyrimidiner Desoxyribonukleoside
JP2003504029A (ja) *	1999-07-01	2003-02-04	グラクソグループリミテッド	ピリミジンデオキシリボヌクレオシド産生のためのベクター、細胞および方法
EP2540540A1 (de)	2011-07-01	2013-01-02	Behr France Rouffach SAS	Heizkörper mit integrierter elektrischer Zusatzheizung
WO2020071538A1 (en)	2018-10-05	2020-04-09	Ajinomoto Co., Inc.	Method for producing target substance by bacterial fermentation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5889194A (ja) *	1981-11-24	1983-05-27	Ajinomoto Co Inc	微生物によるｌ−トリプトフアンの製造法
JPS61104795A (ja) *	1984-10-26	1986-05-23	Takeda Chem Ind Ltd	ウリジンの製造法

1989
- 1989-01-27 JP JP1018939A patent/JPH022349A/ja active Pending
- 1989-02-14 EP EP89102479A patent/EP0329062B1/de not_active Expired - Lifetime
- 1989-02-14 DE DE68915301T patent/DE68915301T2/de not_active Expired - Fee Related
- 1989-02-14 AT AT89102479T patent/ATE105855T1/de not_active IP Right Cessation
- 1989-02-14 ES ES89102479T patent/ES2052789T3/es not_active Expired - Lifetime
- 1989-02-16 KR KR1019890001797A patent/KR890013180A/ko not_active Withdrawn
- 1989-02-17 CN CN89100889A patent/CN1035129A/zh active Pending

Also Published As

Publication number	Publication date
EP0329062B1 (de)	1994-05-18
DE68915301T2 (de)	1994-09-22
KR890013180A (ko)	1989-09-21
ES2052789T3 (es)	1994-07-16
JPH022349A (ja)	1990-01-08
EP0329062A2 (de)	1989-08-23
CN1035129A (zh)	1989-08-30
DE68915301D1 (de)	1994-06-23
EP0329062A3 (en)	1990-08-16

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Legal Events

Date	Code	Title	Description
1994-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties