DK0469837T3 - Anvendelse af en forbindelse til fremstilling af et lægemiddel til sænkning af blodets urinsyreindhold - Google Patents

Anvendelse af en forbindelse til fremstilling af et lægemiddel til sænkning af blodets urinsyreindhold

Info

Publication number: DK0469837T3
Authority: DK; Denmark
Prior art keywords: compound; uric acid; blood uric; lowering; medicament
Prior art date: 1990-08-02

Application number

DK91306944.9T

Other languages

English (en)

Inventor

Paden C Going

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-02

Filing date

1991-07-29

Publication date

1994-12-27

1991-07-29 Application filed by Pfizer filed Critical Pfizer

1994-12-27 Application granted granted Critical

1994-12-27 Publication of DK0469837T3 publication Critical patent/DK0469837T3/da

Links

LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title abstract 2
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title abstract 2
239000008280 blood Substances 0.000 title abstract 2
210000004369 blood Anatomy 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title abstract 2
229940116269 uric acid Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
201000005569 Gout Diseases 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
206010018634 Gouty Arthritis Diseases 0.000 abstract 1
235000011054 acetic acid Nutrition 0.000 abstract 1
150000001242 acetic acid derivatives Chemical class 0.000 abstract 1
150000001243 acetic acids Chemical class 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
239000000651 prodrug Chemical group 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK91306944.9T 1990-08-02 1991-07-29 Anvendelse af en forbindelse til fremstilling af et lægemiddel til sænkning af blodets urinsyreindhold DK0469837T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/562,096 US5064830A (en)	1990-08-02	1990-08-02	Lowering of blood uric acid levels

Publications (1)

Publication Number	Publication Date
DK0469837T3 true DK0469837T3 (da)	1994-12-27

Family

ID=24244779

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91306944.9T DK0469837T3 (da)	1990-08-02	1991-07-29	Anvendelse af en forbindelse til fremstilling af et lægemiddel til sænkning af blodets urinsyreindhold

Country Status (16)

Country	Link
US (1)	US5064830A (da)
EP (1)	EP0469837B1 (da)
JP (1)	JPH04234321A (da)
KR (1)	KR940002665B1 (da)
AT (1)	ATE113840T1 (da)
AU (1)	AU622590B2 (da)
CA (1)	CA2048235C (da)
DE (1)	DE69105069T2 (da)
DK (1)	DK0469837T3 (da)
HU (1)	HUT61665A (da)
IE (1)	IE64046B1 (da)
IL (1)	IL98979A (da)
MX (1)	MX9100450A (da)
NZ (1)	NZ239215A (da)
PT (1)	PT98509B (da)
ZA (1)	ZA916060B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5391551A (en) *	1993-05-10	1995-02-21	Pfizer Inc.	Method of lowering blood lipid levels
IL120264A0 (en) *	1996-02-29	1997-06-10	Pfizer	Method of reducing tissue damage associated with non-cardiac ischemia
IL124236A (en) *	1997-05-05	2003-01-12	Pfizer	Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor
WO2011046800A1 (en) *	2009-10-13	2011-04-21	Wellstat Therapeutics Corporation	3-substituted compounds for reducing uric acid
WO2017176777A1 (en) *	2016-04-04	2017-10-12	Aviragen Therapeutics, Inc.	Bta-c585 for the treatment and/or prevention of conditions related to or associated with hyperuricemia or hyperuricosuria and other conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4939140A (en) *	1985-11-07	1990-07-03	Pfizer Inc.	Heterocyclic oxophthalazinyl acetic acids
ES2032749T3 (es) *	1985-11-07	1993-03-01	Pfizer Inc.	Acidos oxoftalazinil-aceticos heterociclicos.
GB8704569D0 (en) *	1987-02-26	1987-04-01	Ici America Inc	Therapeutic agent
JPH0676391B2 (ja) *	1987-06-09	1994-09-28	フアイザー・インコーポレイテツド	ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
EP0322153A3 (en) *	1987-12-21	1990-08-16	Pfizer Inc.	Heterocyclic oxophtalazinyl acetic acids

1990
- 1990-08-02 US US07/562,096 patent/US5064830A/en not_active Expired - Lifetime
1991
- 1991-07-27 IL IL9897991A patent/IL98979A/en not_active IP Right Cessation
- 1991-07-29 DK DK91306944.9T patent/DK0469837T3/da active
- 1991-07-29 DE DE69105069T patent/DE69105069T2/de not_active Expired - Fee Related
- 1991-07-29 EP EP91306944A patent/EP0469837B1/en not_active Expired - Lifetime
- 1991-07-29 AT AT91306944T patent/ATE113840T1/de not_active IP Right Cessation
- 1991-07-31 PT PT98509A patent/PT98509B/pt active IP Right Grant
- 1991-07-31 MX MX9100450A patent/MX9100450A/es unknown
- 1991-07-31 CA CA002048235A patent/CA2048235C/en not_active Expired - Fee Related
- 1991-08-01 NZ NZ239215A patent/NZ239215A/en unknown
- 1991-08-01 HU HU912567A patent/HUT61665A/hu unknown
- 1991-08-01 ZA ZA916060A patent/ZA916060B/xx unknown
- 1991-08-01 JP JP3193231A patent/JPH04234321A/ja active Pending
- 1991-08-01 AU AU81560/91A patent/AU622590B2/en not_active Ceased
- 1991-08-01 KR KR1019910013330A patent/KR940002665B1/ko not_active Expired - Fee Related
- 1991-08-01 IE IE272191A patent/IE64046B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69105069T2 (de)	1995-03-09
DE69105069D1 (de)	1994-12-15
PT98509A (pt)	1992-06-30
JPH04234321A (ja)	1992-08-24
IE912721A1 (en)	1992-02-12
KR940002665B1 (ko)	1994-03-28
AU8156091A (en)	1992-02-06
AU622590B2 (en)	1992-04-09
PT98509B (pt)	1999-01-29
EP0469837B1 (en)	1994-11-09
KR920003970A (ko)	1992-03-27
US5064830A (en)	1991-11-12
NZ239215A (en)	1997-07-27
IE64046B1 (en)	1995-06-28
IL98979A0 (en)	1992-07-15
IL98979A (en)	1996-11-14
ATE113840T1 (de)	1994-11-15
CA2048235C (en)	1995-05-30
HU912567D0 (en)	1992-01-28
EP0469837A3 (en)	1992-04-08
EP0469837A2 (en)	1992-02-05
MX9100450A (es)	1992-04-01
HUT61665A (en)	1993-03-01
ZA916060B (en)	1993-03-31

Publication	Publication Date	Title
FI873631A0 (fi)	1987-08-21	--alkyl-4-amino-3-kinolinmetanoler och 1-(4-aralkylamino-3-kinolinyl)alkanoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI904327A0 (fi)	1990-09-03	N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
DE3773660D1 (de)	1991-11-14	Morpholinoethylester von mycophenolsaeure und ihre derivate, ihre herstellung und verwendung in pharmazeutische zusammensetzungen.
NO963450D0 (no)	1996-08-19	Heterocykliske aromatiske oksazolforbindelser og deres anvendelse
DE68920654D1 (de)	1995-03-02	4-Oxochinolin-3-carbonsäure-Derivate, ihre Herstellung und ihre Verwendung.
DE69418789D1 (de)	1999-07-08	2-(Piperidin-4-yl, Pyridin-4-yl und Tetrahydropyridin-4-yl)-benzofuran-7-carbamat Derivate, ihre Herstellung und Verwendung als Acetylcholinesterase Inhibitoren
DK132188A (da)	1988-09-13	Anvendelse af tetrahydrobenz(c,d)indol-6-carboxamider som anxiolytika
SE8802412D0 (sv)	1988-06-28	Thiourea derivatives
DK0469837T3 (da)	1994-12-27	Anvendelse af en forbindelse til fremstilling af et lægemiddel til sænkning af blodets urinsyreindhold
IL78954A (en)	1989-09-28	Hydantoin spirocondensed with benzopyran and quinoline derivatives and pharmaceutical compositions containing them
DK544689D0 (da)	1989-11-01	Terapeutisk aktive forbindelser
DE69110219D1 (de)	1995-07-13	3-(1H-Indazol-3-yl)-4-pyridiname, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DK215886D0 (da)	1986-05-09	1,3-oxathianderivater
DK0676199T3 (da)	1999-02-08	Anvendelse af trovafloxacin eller derivater deraf til fremstilling af et medikament til behandling af H. pylori-infektione
DK369579A (da)	1980-03-09	Hydroxyeddikesyrederivater
ATE63899T1 (de)	1991-06-15	8-(niederalkyl)bicyclo(4.2.0>octanderivate mit wertvollen therapeutischen eigenschaften.
AU5920486A (en)	1987-01-08	6,9-epoxy-7-fluoro-11-hydroxy-prost-5-en-1-oic acid derivatives
FI922482L (fi)	1992-05-29	Foerfarande foer framstaellning av kinolinfoerening.
DE3766236D1 (de)	1990-12-20	Dibenzo(be)oxepinessigsaeure-derivate, deren herstellung und therapeutische verwendung.