ATE107665T1 - Proteaseresistenter pdgf und dessen verwendungen. - Google Patents

Proteaseresistenter pdgf und dessen verwendungen.

Info

Publication number: ATE107665T1
Authority: AT; Austria
Prior art keywords: pdgf; polypeptides; proteins; chain; protease resistant
Prior art date: 1990-07-23

Application number

AT91913764T

Other languages

English (en)

Inventor

Mark J Murray

Original Assignee

Zymogenetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-23

Filing date

1991-07-22

Publication date

1994-07-15

1991-07-22 Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc

1994-07-15 Application granted granted Critical

1994-07-15 Publication of ATE107665T1 publication Critical patent/ATE107665T1/de

Links

108091005804 Peptidases Proteins 0.000 title 1
239000004365 Protease Substances 0.000 title 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
229920001184 polypeptide Polymers 0.000 abstract 4
102000004196 processed proteins & peptides Human genes 0.000 abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
102000004169 proteins and genes Human genes 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 3
239000004472 Lysine Substances 0.000 abstract 1
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
206010052428 Wound Diseases 0.000 abstract 1
208000027418 Wounds and injury Diseases 0.000 abstract 1
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
239000006143 cell culture medium Substances 0.000 abstract 1
210000004748 cultured cell Anatomy 0.000 abstract 1
230000037430 deletion Effects 0.000 abstract 1
238000012217 deletion Methods 0.000 abstract 1
230000035876 healing Effects 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Enzymes And Modification Thereof (AREA)

AT91913764T 1990-07-23 1991-07-22 Proteaseresistenter pdgf und dessen verwendungen. ATE107665T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US55721990A	1990-07-23	1990-07-23

Publications (1)

Publication Number	Publication Date
ATE107665T1 true ATE107665T1 (de)	1994-07-15

Family

ID=24224518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91913764T ATE107665T1 (de)	1990-07-23	1991-07-22	Proteaseresistenter pdgf und dessen verwendungen.

Country Status (10)

Country	Link
US (2)	US5895755A (de)
EP (1)	EP0547064B1 (de)
JP (1)	JP2823690B2 (de)
AT (1)	ATE107665T1 (de)
AU (1)	AU8294991A (de)
CA (1)	CA2087969C (de)
DE (1)	DE69102651T2 (de)
DK (1)	DK0547064T3 (de)
ES (1)	ES2055611T3 (de)
WO (1)	WO1992001716A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030105007A1 (en) *	1995-06-07	2003-06-05	Andre Beaulieu	PDGF-betabeta and fibronectin combined in a solid wound dressing for the treatment of wounds
ES2293137T3 (es) *	1995-10-11	2008-03-16	Novartis Vaccines And Diagnostics, Inc.	Combinacion de pdgf, kgf,igf e igfbp para curacion de heridas.
EP0948538B1 (de)	1996-12-13	2008-06-11	Novartis Vaccines and Diagnostics, Inc.	Analyse und separation von pdgf-proteinen
EP1584685B1 (de)	1998-02-05	2011-04-13	GlaxoSmithKline Biologicals SA	Tumorassoziierte Antigenderivate der Mage-Familie, zur Herstellung von Fusionsproteinen mit T-Helper Epitope und Zusammensetzungen zur Impfung
US7608258B2 (en) *	2002-04-13	2009-10-27	Allan Mishra	Method for treatment of tendinosis using platelet rich plasma
US6811777B2 (en) *	2002-04-13	2004-11-02	Allan Mishra	Compositions and minimally invasive methods for treating incomplete connective tissue repair
JP2006517586A (ja) *	2003-02-04	2006-07-27	ラドウィグインスティテュートフォーキャンサーリサーチ	幹細胞のｖｅｇｆ−ｂ及びｐｄｇｆ調節
US20070122906A1 (en) *	2003-12-29	2007-05-31	Allan Mishra	Method of culturing cells
US20070110737A1 (en) *	2003-12-29	2007-05-17	Allan Mishra	Compositions and method for decreasing the appearance of skin wrinkles
US7678780B2 (en) *	2003-12-29	2010-03-16	Allan Mishra	Method of treating cancer using platelet releasate
US7462268B2 (en)	2004-08-20	2008-12-09	Allan Mishra	Particle/cell separation device and compositions
FR2891149B1 (fr)	2005-09-26	2007-11-30	Biodex Sarl	Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US20100112081A1 (en)	2008-10-07	2010-05-06	Bioparadox, Llc	Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
US20140356893A1 (en)	2013-06-04	2014-12-04	Allan Mishra	Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
CN105085652B (zh) *	2014-05-16	2021-06-22	中国人民解放军军事医学科学院生物工程研究所	血小板衍生生长因子b突变体、其制备方法及用途
AU2015332556B2 (en)	2014-10-14	2021-04-29	Samuel Lynch	Compositions for treating wounds
US12344666B2 (en)	2021-06-09	2025-07-01	Washington University	PDGF mutants and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4766073A (en) *	1985-02-25	1988-08-23	Zymogenetics Inc.	Expression of biologically active PDGF analogs in eucaryotic cells
US4801542A (en) *	1984-10-12	1989-01-31	Zymogenetics, Inc.	Expression of biologically active PDGF analogs in eucaryotic cells
US5045633A (en) *	1985-02-25	1991-09-03	Zymogenetics, Inc.	Expression of biologically active PDGF analogs in eucaryotic cells
ATE131532T1 (de) *	1986-08-13	1995-12-15	Zymogenetics Inc	Expression von biologisch-aktiven pdgf-analogen in eukaryotischen zellen
WO1988007057A1 (en) *	1987-03-13	1988-09-22	Amgen Inc.	Purified platelet-derived growth factor and methods for purification thereof
DE3834079A1 (de) *	1988-10-06	1990-04-12	Biotechnolog Forschung Gmbh	Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren
GB9101645D0 (en) *	1991-01-25	1991-03-06	British Bio Technology	Compounds

1991
- 1991-07-22 DE DE69102651T patent/DE69102651T2/de not_active Expired - Fee Related
- 1991-07-22 DK DK91913764.6T patent/DK0547064T3/da active
- 1991-07-22 EP EP91913764A patent/EP0547064B1/de not_active Expired - Lifetime
- 1991-07-22 AT AT91913764T patent/ATE107665T1/de not_active IP Right Cessation
- 1991-07-22 AU AU82949/91A patent/AU8294991A/en not_active Abandoned
- 1991-07-22 JP JP3512963A patent/JP2823690B2/ja not_active Expired - Fee Related
- 1991-07-22 WO PCT/US1991/005183 patent/WO1992001716A1/en not_active Ceased
- 1991-07-22 ES ES91913764T patent/ES2055611T3/es not_active Expired - Lifetime
- 1991-07-22 CA CA002087969A patent/CA2087969C/en not_active Expired - Fee Related
1994
- 1994-09-09 US US08/303,594 patent/US5895755A/en not_active Expired - Lifetime
1995
- 1995-05-08 US US08/436,140 patent/US5905142A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0547064B1 (de)	1994-06-22
EP0547064A1 (de)	1993-06-23
DE69102651T2 (de)	1994-10-06
WO1992001716A1 (en)	1992-02-06
CA2087969A1 (en)	1992-01-24
ES2055611T3 (es)	1994-08-16
DK0547064T3 (da)	1995-03-20
AU8294991A (en)	1992-02-18
DE69102651D1 (de)	1994-07-28
JPH05508775A (ja)	1993-12-09
US5905142A (en)	1999-05-18
JP2823690B2 (ja)	1998-11-11
CA2087969C (en)	2001-10-16
US5895755A (en)	1999-04-20

Legal Events

Date	Code	Title	Description
1995-02-15	UEP	Publication of translation of european patent specification
2011-10-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE107665T1 (de)	1994-07-15	Proteaseresistenter pdgf und dessen verwendungen.
ATE198754T1 (de)	2001-02-15	Antikörper gegen saugetier-interleukin-4 und peptide verwendbar als antigenen für deren herstellung
FI852547L (fi)	1985-06-27	Framstaellning av faktor viii och daertill hoerande produkter.
DK0789766T3 (da)	2004-05-24	Kimæriske papillomaviruslignende partikler
DK1115840T3 (da)	2010-04-12	Afstamningsspecifikke celler og progenitorceller
ATE142692T1 (de)	1996-09-15	Herstellung von hämoglobin und analogen davon durch bakterien oder hefen
DE69535328D1 (de)	2007-01-18	In-vitro wachstum von langerhans'schen inseln und ihre verwendungen
EP0434713A4 (en)	1992-05-20	Hiv-1 envelope muteins lacking hypervariable domains
ATE91714T1 (de)	1993-08-15	Transformation von trichoderma.
GR80840B (en)	1985-02-26	Novel polypeptide with a - amylase inhibiting effect, method for the preparation thereof, use and pharmaceutical preparations thereof
ES8600389A1 (es)	1985-10-01	Procedimiento para la produccion de una linea celular humana independiente de suero
GR3025180T3 (en)	1998-02-27	Biomaterial based on collagen and its applications
DE69939330D1 (de)	2008-09-25	Wachstumsfaktor-homologe zvegf-3
ATE125268T1 (de)	1995-08-15	Säureempfindliche subeinheit eines insulinähnlichen wachstumfaktors-bindeprotein- komplexes.
EP0336779A3 (de)	1991-08-21	Durch kovalenten Ersatz von Wasserstoffbrücken stabilisierte Polypeptide
EP1702071A4 (de)	2007-07-25	Transaktivierungssystem für säugerzellen
ES2052513T3 (es)	1994-07-16	Nuevos polipeptidos, su fabricacion y empleo.
ES2047946T3 (es)	1994-03-01	Metodos de cultivos celulares para producir proteina c activada.
DE3667472D1 (de)	1990-01-18	Analoge von hypokalzemischen polypeptiden, welche den kalziumgehalt des koerpers schonen, deren herstellung, deren verwendung als arznei und diese enthaltende zusammensetzungen.
GR3006212T3 (de)	1993-06-21
WO1994011510A3 (en)	1994-09-15	Modulators of hematopoietic progenitor cells
JPS6434371A (en)	1989-02-03	Periosteal bone forming material
裴雪涛	1995	Human primitive hematopoietic progenitor cells are more enriched in CD34^+ CD38^-population than in CD34^+ CD38^+ population