ATE10804T1 - Ein diphenylhydantoin-derivat enthaltende pharmazeutische zusammensetzung, verwendete derivate und ihre herstellung. - Google Patents

Ein diphenylhydantoin-derivat enthaltende pharmazeutische zusammensetzung, verwendete derivate und ihre herstellung.

Info

Publication number: ATE10804T1
Authority: AT; Austria
Prior art keywords: pharmaceutical composition; diphenylhydantoin; derivative; preparation; composition containing
Prior art date: 1979-02-20

Application number

AT80200137T

Other languages

English (en)

Inventor

Pierre Dumont

Jacques Poupaert

Original Assignee

Region Wallonne Representee Par Le Ministre Des Technologies Nouvelles De La Region Wallonne

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-02-20

Filing date

1980-02-18

Publication date

1985-01-15

1980-02-18 Application filed by Region Wallonne Representee Par Le Ministre Des Technologies Nouvelles De La Region Wallonne filed Critical Region Wallonne Representee Par Le Ministre Des Technologies Nouvelles De La Region Wallonne

1985-01-15 Application granted granted Critical

1985-01-15 Publication of ATE10804T1 publication Critical patent/ATE10804T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
CXOFVDLJLONNDW-UHFFFAOYSA-N Phenytoin Chemical class N1C(=O)NC(=O)C1(C=1C=CC=CC=1)C1=CC=CC=C1 CXOFVDLJLONNDW-UHFFFAOYSA-N 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 2
239000000470 constituent Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
230000000506 psychotropic effect Effects 0.000 abstract 2
MPAFAYXEPQCBPP-UHFFFAOYSA-N 1-phenylimidazolidine-2,4-dione Chemical class O=C1NC(=O)CN1C1=CC=CC=C1 MPAFAYXEPQCBPP-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

AT80200137T 1979-02-20 1980-02-18 Ein diphenylhydantoin-derivat enthaltende pharmazeutische zusammensetzung, verwendete derivate und ihre herstellung. ATE10804T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7904209A FR2449448B1 (fr)	1979-02-20	1979-02-20	Composition pharmaceutique comprenant un derive de phenylhydantoine, derives mis en oeuvre et leur preparation
EP80200137A EP0015038B1 (de)	1979-02-20	1980-02-18	Ein Diphenylhydantoin-Derivat enthaltende pharmazeutische Zusammensetzung, verwendete Derivate und ihre Herstellung

Publications (1)

Publication Number	Publication Date
ATE10804T1 true ATE10804T1 (de)	1985-01-15

Family

ID=9222166

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT80200137T ATE10804T1 (de)	1979-02-20	1980-02-18	Ein diphenylhydantoin-derivat enthaltende pharmazeutische zusammensetzung, verwendete derivate und ihre herstellung.

Country Status (11)

Country	Link
US (1)	US4304782A (de)
EP (1)	EP0015038B1 (de)
JP (1)	JPS55133362A (de)
AT (1)	ATE10804T1 (de)
CA (1)	CA1139672A (de)
DE (1)	DE3069813D1 (de)
DK (1)	DK71780A (de)
ES (1)	ES8200011A1 (de)
FI (1)	FI71556C (de)
FR (1)	FR2449448B1 (de)
NO (1)	NO152047C (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07106837B2 (ja) *	1989-01-31	1995-11-15	シャープ株式会社	シート状体の循環式供給装置
US5411981A (en) *	1991-01-09	1995-05-02	Roussel Uclaf	Phenylimidazolidines having antiandrogenic activity
USRE35956E (en) *	1991-01-09	1998-11-10	Roussel Uclaf	Phenylimidazolidines having antiandrogenic activity
JPH04297461A (ja) *	1991-03-27	1992-10-21	Otsuka Pharmaceut Factory Inc	２−チオヒダントイン誘導体
ES2293638T3 (es) *	1994-03-25	2008-03-16	Isotechnika, Inc.	Mejora de la eficacia de farmacos por deuteracion.
US6334997B1 (en)	1994-03-25	2002-01-01	Isotechnika, Inc.	Method of using deuterated calcium channel blockers
AU1917899A (en) *	1998-03-20	1999-10-18	Warner-Lambert Company	Crystalline sodium phenytoin monohydrate
JP2002507603A (ja) *	1998-03-25	2002-03-12	ブリストル−マイヤーズスクイブカンパニー	イミダゾロン食欲抑制薬：ｉ．非環式誘導体
DE10214228A1 (de) *	2002-03-22	2003-10-02	Bdd Group Holding Ag Zug	Deuterierte substitutierte Indole sowie diese Verbindungen enthaltende Arzneimittel
DE602004031881D1 (de) *	2003-12-19	2011-04-28	Univ California	Verfahren und materialien zur beurteilung von prostatakrebstherapien
US7718684B2 (en) *	2004-02-24	2010-05-18	The Regents Of The University Of California	Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) *	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
EP2656842B1 (de)	2006-03-27	2016-08-10	The Regents of The University of California	Androgenrezeptor-modulator zur behandlung von prostatakrebs und androgenrezeptor-assoziierte erkrankungen
WO2007127010A2 (en) *	2006-03-29	2007-11-08	The Regents Of The University Of California	Diarylthiohydantoin compounds
CA2966280A1 (en)	2007-10-26	2009-04-30	The Regents Of The University Of California	Diarylhydantoin compounds
HUE037389T2 (hu)	2010-02-16	2018-08-28	Aragon Pharmaceuticals Inc	Androgén receptor modulátorok és alkalmazásaik
ES2836424T3 (es)	2012-09-26	2021-06-25	Aragon Pharmaceuticals Inc	Antiandrógenos para tratar el cáncer de próstata no metastásico y resistente a la castración
CA3105575A1 (en)	2013-01-15	2014-07-24	Aragon Pharmaceuticals, Inc.	Androgen receptor modulator and uses thereof
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
UA129105C2 (uk)	2017-10-16	2025-01-15	Арагон Фармасьютикалз, Інк.	Антиандрогени для лікування неметастатичного резистентного до кастрації раку передміхурової залози

1979
- 1979-02-20 FR FR7904209A patent/FR2449448B1/fr not_active Expired
1980
- 1980-02-18 EP EP80200137A patent/EP0015038B1/de not_active Expired
- 1980-02-18 DE DE8080200137T patent/DE3069813D1/de not_active Expired
- 1980-02-18 AT AT80200137T patent/ATE10804T1/de not_active IP Right Cessation
- 1980-02-19 DK DK71780A patent/DK71780A/da not_active Application Discontinuation
- 1980-02-19 NO NO800447A patent/NO152047C/no unknown
- 1980-02-19 CA CA000346003A patent/CA1139672A/en not_active Expired
- 1980-02-20 US US06/122,903 patent/US4304782A/en not_active Expired - Lifetime
- 1980-02-20 FI FI800502A patent/FI71556C/fi not_active IP Right Cessation
- 1980-02-20 JP JP2034780A patent/JPS55133362A/ja active Pending
- 1980-02-20 ES ES488788A patent/ES8200011A1/es not_active Expired

Also Published As

Publication number	Publication date
EP0015038A1 (de)	1980-09-03
NO800447L (no)	1980-08-21
FI71556B (fi)	1986-10-10
JPS55133362A (en)	1980-10-17
FI800502A7 (fi)	1980-08-21
ES488788A0 (es)	1981-10-16
FR2449448B1 (fr)	1983-05-27
US4304782A (en)	1981-12-08
NO152047B (no)	1985-04-15
DE3069813D1 (en)	1985-01-31
EP0015038B1 (de)	1984-12-19
FR2449448A1 (fr)	1980-09-19
FI71556C (fi)	1987-01-19
DK71780A (da)	1980-08-21
NO152047C (no)	1985-07-24
ES8200011A1 (es)	1981-10-16
CA1139672A (en)	1983-01-18

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Legal Events

Date	Code	Title	Description
1985-05-15	UEP	Publication of translation of european patent specification
1987-11-15	REN	Ceased due to non-payment of the annual fee