ATE108795T1 - Herstellung von diazabicyclischen zwischenprodukten. - Google Patents

Herstellung von diazabicyclischen zwischenprodukten.

Info

Publication number: ATE108795T1
Authority: AT; Austria
Prior art keywords: diazabicyclic; production; intermediate products; diazabicyclo; proline
Prior art date: 1989-05-11

Application number

AT90304442T

Other languages

English (en)

Inventor

Tamin Fehme Braish

Darrell Eugene Fox

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-11

Filing date

1990-04-25

Publication date

1994-08-15

1990-04-25 Application filed by Pfizer filed Critical Pfizer

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE108795T1 publication Critical patent/ATE108795T1/de

Links

239000013067 intermediate product Substances 0.000 title 1
239000000543 intermediate Substances 0.000 abstract 2
AVGHIQUXSVAJBC-UHFFFAOYSA-N 1,2-diazabicyclo[2.2.1]heptane Chemical compound C1C2CCN1NC2 AVGHIQUXSVAJBC-UHFFFAOYSA-N 0.000 abstract 1
LLSRLLPHUVVLQJ-UHFFFAOYSA-N 1-cycloheptyldiazepane Chemical class C1CCCCCC1N1NCCCCC1 LLSRLLPHUVVLQJ-UHFFFAOYSA-N 0.000 abstract 1
PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
PMMYEEVYMWASQN-QWWZWVQMSA-N cis-4-hydroxy-D-proline Chemical compound O[C@H]1C[NH2+][C@@H](C([O-])=O)C1 PMMYEEVYMWASQN-QWWZWVQMSA-N 0.000 abstract 1
229960002591 hydroxyproline Drugs 0.000 abstract 1
150000007660 quinolones Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT90304442T 1989-05-11 1990-04-25 Herstellung von diazabicyclischen zwischenprodukten. ATE108795T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US35042389A	1989-05-11	1989-05-11
US07/423,063 US5036153A (en)	1989-05-11	1989-10-18	Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates

Publications (1)

Publication Number	Publication Date
ATE108795T1 true ATE108795T1 (de)	1994-08-15

Family

ID=26996610

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90304442T ATE108795T1 (de)	1989-05-11	1990-04-25	Herstellung von diazabicyclischen zwischenprodukten.

Country Status (21)

Country	Link
US (1)	US5036153A (de)
EP (1)	EP0397351B1 (de)
JP (1)	JPH035482A (de)
KR (1)	KR920003560B1 (de)
CN (1)	CN1025852C (de)
AT (1)	ATE108795T1 (de)
AU (1)	AU637099B2 (de)
CA (1)	CA2016343C (de)
CZ (1)	CZ279947B6 (de)
DE (1)	DE69010761T2 (de)
DK (1)	DK0397351T3 (de)
ES (1)	ES2056381T3 (de)
FI (1)	FI96682C (de)
HU (1)	HU206718B (de)
IE (1)	IE64185B1 (de)
IL (1)	IL94303A (de)
NO (1)	NO902072L (de)
NZ (1)	NZ233624A (de)
PT (1)	PT93986B (de)
RU (1)	RU2024524C1 (de)
YU (1)	YU48131B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196548A (en) *	1989-05-11	1993-03-23	Pfizer Inc.	Preparation of diazabicyclic Intermediates
US5128483A (en) *	1989-07-19	1992-07-07	American Cyanamid Company	Dibromovinyl and acetylene-1-pyrrolidinecarboxylic acid intermediates
US5254696A (en) *	1990-09-13	1993-10-19	Bayer Aktiengesellschaft	N-acylpyrrolidine derivatives
DE4029054A1 (de) *	1990-09-13	1992-03-19	Bayer Ag	N-acylpyrrolidin-derivate
AT403803B (de)	1996-04-19	1998-05-25	Sanochemia Ltd	Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
US6589978B2 (en) *	2000-06-30	2003-07-08	Hoffman-La Roche Inc.	1-sulfonyl pyrrolidine derivatives
JP4827154B2 (ja) *	2001-07-25	2011-11-30	株式会社オーイズミ	遊技装置
TW200303742A (en) *	2001-11-21	2003-09-16	Novartis Ag	Organic compounds
JP4631262B2 (ja) *	2003-10-07	2011-02-16	東レ・ファインケミカル株式会社	（シス）−４−ヒドロキシプロリン誘導体の製造方法
JP2007244428A (ja) *	2006-03-13	2007-09-27	Olympia:Kk	メダル貸出機
JP4771416B2 (ja) *	2006-03-22	2011-09-14	サミー株式会社	遊技機
CN102180824B (zh) *	2011-02-18	2012-11-14	华东理工大学	吡咯衍生物的制备方法
CN103755710B (zh) *	2014-01-14	2015-08-12	昆明理工大学	一类2,5-二氮杂双环庚烷类化合物及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3083208A (en) *	1961-05-11	1963-03-26	Mead Johnson & Co	1-acyl and 1-carbalkoxy-3-pyrrolidinols
NL124628C (de) *	1963-02-05
US3459768A (en) *	1966-05-24	1969-08-05	Richardson Merrell Inc	Pyrrolidine-2,2-dimethanols and methods of preparing the same
US3947445A (en) *	1974-05-09	1976-03-30	Stanford Research Institute	Diazabicyclooctanes and diazabicycloheptanes
US3905979A (en) *	1974-05-09	1975-09-16	Stanford Research Inst	Diazabicyclooctanes and diazabicycloheptanes
HU184960B (en) *	1981-07-20	1984-11-28	Richter Gedeon Vegyeszet	Process for preparing new derivatives of 3,7-diazabicyclo/3.3.1/ nonane
US4539411A (en) *	1982-02-05	1985-09-03	Hoffmann-La Roche Inc.	Rhodium complexes of chiral phosphines
JPS60190760A (ja) *	1984-03-09	1985-09-28	Mitsubishi Chem Ind Ltd	ピロリジン誘導体及びその製造法
US4571396A (en) *	1984-04-16	1986-02-18	Warner-Lambert Company	Antibacterial agents
IN166416B (de) *	1985-09-18	1990-05-05	Pfizer
JPS63162672A (ja) *	1986-12-25	1988-07-06	Ono Pharmaceut Co Ltd	新規なプロリナ−ル誘導体、それらの製造方法およびそれらを含有する抗健忘症剤
US4923879A (en) *	1987-07-31	1990-05-08	Warner-Lambert Company	1,8-Naphthyridines and their use as antibacterial agents
GB8800694D0 (en) *	1988-01-13	1988-02-10	Pfizer Ltd	Antiarrhythmic agents

1989
- 1989-10-18 US US07/423,063 patent/US5036153A/en not_active Expired - Lifetime
1990
- 1990-04-25 DE DE69010761T patent/DE69010761T2/de not_active Expired - Fee Related
- 1990-04-25 DK DK90304442.8T patent/DK0397351T3/da active
- 1990-04-25 ES ES90304442T patent/ES2056381T3/es not_active Expired - Lifetime
- 1990-04-25 EP EP90304442A patent/EP0397351B1/de not_active Expired - Lifetime
- 1990-04-25 AT AT90304442T patent/ATE108795T1/de not_active IP Right Cessation
- 1990-05-06 IL IL9430390A patent/IL94303A/en not_active IP Right Cessation
- 1990-05-08 CZ CS902279A patent/CZ279947B6/cs not_active IP Right Cessation
- 1990-05-09 PT PT93986A patent/PT93986B/pt not_active IP Right Cessation
- 1990-05-09 CA CA002016343A patent/CA2016343C/en not_active Expired - Lifetime
- 1990-05-09 NZ NZ233624A patent/NZ233624A/en unknown
- 1990-05-10 HU HU902994A patent/HU206718B/hu not_active IP Right Cessation
- 1990-05-10 NO NO90902072A patent/NO902072L/no unknown
- 1990-05-10 FI FI902334A patent/FI96682C/fi active IP Right Grant
- 1990-05-10 IE IE168990A patent/IE64185B1/en not_active IP Right Cessation
- 1990-05-10 CN CN90102798A patent/CN1025852C/zh not_active Expired - Lifetime
- 1990-05-10 KR KR1019900006578A patent/KR920003560B1/ko not_active Expired
- 1990-05-10 AU AU54908/90A patent/AU637099B2/en not_active Ceased
- 1990-05-10 YU YU91390A patent/YU48131B/sh unknown
- 1990-05-10 RU SU904743987A patent/RU2024524C1/ru not_active IP Right Cessation
- 1990-05-11 JP JP2122831A patent/JPH035482A/ja active Pending

Also Published As

Publication number	Publication date
CA2016343A1 (en)	1990-11-11
US5036153A (en)	1991-07-30
NO902072D0 (no)	1990-05-10
CN1025852C (zh)	1994-09-07
KR900018104A (ko)	1990-12-20
YU91390A (en)	1991-10-31
EP0397351A1 (de)	1990-11-14
CZ279947B6 (cs)	1995-09-13
FI902334A0 (fi)	1990-05-10
IL94303A (en)	1995-08-31
AU637099B2 (en)	1993-05-20
CA2016343C (en)	1998-01-27
ES2056381T3 (es)	1994-10-01
DK0397351T3 (da)	1994-08-22
FI96682B (fi)	1996-04-30
HU206718B (en)	1992-12-28
IE64185B1 (en)	1995-07-12
YU48131B (sh)	1997-05-28
EP0397351B1 (de)	1994-07-20
PT93986A (pt)	1991-01-08
FI96682C (fi)	1996-08-12
IL94303A0 (en)	1991-03-10
DE69010761T2 (de)	1994-10-27
KR920003560B1 (ko)	1992-05-04
JPH035482A (ja)	1991-01-11
IE901689L (en)	1990-11-11
HU902994D0 (en)	1990-09-28
NO902072L (no)	1990-11-12
PT93986B (pt)	1996-11-29
HUT59926A (en)	1992-07-28
NZ233624A (en)	1992-04-28
CN1047295A (zh)	1990-11-28
DE69010761D1 (de)	1994-08-25
AU5490890A (en)	1990-11-15
RU2024524C1 (ru)	1994-12-15
CZ227990A3 (en)	1995-04-12

Legal Events

Date	Code	Title	Description
2010-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE200279T1 (de)	2001-04-15	Herstellung von 3,4,4-trisubstituiertem piperidinyl-n-alkylcarboxylaten und zwischenverbindungen, verwendbar als opioid antagonisten
DE69023948D1 (de)	1996-01-18	Herstellung von peroxidhaltigen Perfluorpolyethern.
NO904625D0 (no)	1990-10-25	Fremgangsmaate for fremstilling av 1h-imidazo 4,5-c kinoliner.
DE69022595D1 (de)	1995-10-26	Herstellung von kohlefaser-halbfabrikaten.
DE59410008D1 (de)	2002-01-24	Verfahren zur Herstellung von Perylen-3,4-dicarbonsäurederivaten
ATE108795T1 (de)	1994-08-15	Herstellung von diazabicyclischen zwischenprodukten.
FI921345A0 (fi)	1992-03-27	Piperidinderivat.
DE3885366D1 (de)	1993-12-09	Verfahren zur Herstellung von Pyrrolo-(3,4-c)pyrrolen.
DE59100670D1 (de)	1994-01-13	Bausatz zur herstellung von büro-arbeitstischen.
DE69416219D1 (de)	1999-03-11	Herstellung von pigmentärem 2,9-Dichlorchinacridon
FI945626A0 (fi)	1994-11-29	Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori-beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi
DE69020172D1 (de)	1995-07-27	Verfahren zur Herstellung von epsilon-Caprolactam.
NO911723L (no)	1991-11-04	Pyrido(2,3-f)(1,4)tiazepiner og pyrido(3,2-b)(1,5)benzotiazepiner.
FI945000A0 (fi)	1994-10-24	Menetelmä (S)-amino-1-substituoitujen pyrrolidiinien valmistamiseksi
FI891473A0 (fi)	1989-03-28	Menetelmä terapeuttisesti käyttökelpoisten 4-aryyli-4-piperidiinikarbinolien valmistamiseksi
FI883759A0 (fi)	1988-08-12	C.12-modifierade etromycin a-derivat.
EP0909759A3 (de)	2000-04-26	Individuelle Stereoisomere von 7-(3-(aminoalkyl)-1-pyrrolidinyl)-Chinolonen als antibakterielle Wirkstoffe
FI93454B (fi)	1994-12-30	Menetelmä terapeuttisesti aktiivisten tiasykloalkeno/3,2-b/pyridiinien valmistamiseksi
ATE66812T1 (de)	1991-09-15	Arzneimittel zur heilung von arteriosklerose, enthaltend ein pyrimido(2,1-b)benzothiazolderivat.
DE69015324D1 (de)	1995-02-02	Herstellung von gegebenenfalls substituierten Chinolincopolymeren.
DE59407667D1 (de)	1999-03-04	Verfahren zur Herstellung von Azaphenothiazinen
DE69014692D1 (de)	1995-01-19	Herstellung von beta-Picolin.
DE59004310D1 (de)	1994-03-03	Verfahren zur Herstellung von 2-(2-Halogenethylthio)-phenylsulfonamiden.
DE59008184D1 (de)	1995-02-16	Verfahren zur Herstellung von Isoxazol-4,5-dicarbonsäure-diestern.