ATE109002T1 - Wasserlösliche antineoplastische taxolderivate. - Google Patents

Wasserlösliche antineoplastische taxolderivate.

Info

Publication number
ATE109002T1
ATE109002T1 AT89903659T AT89903659T ATE109002T1 AT E109002 T1 ATE109002 T1 AT E109002T1 AT 89903659 T AT89903659 T AT 89903659T AT 89903659 T AT89903659 T AT 89903659T AT E109002 T1 ATE109002 T1 AT E109002T1
Authority
AT
Austria
Prior art keywords
water soluble
taxol derivatives
soluble antineoplastic
antineoplastic taxol
derivatives
Prior art date
Application number
AT89903659T
Other languages
English (en)
Inventor
Rudiger D Haugwitz
Matthew Suffness
Venkatachala L Narayanan
Leon Zalkow
Howard M Deutsch
Jan A Glinski
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE109002T1 publication Critical patent/ATE109002T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
AT89903659T 1988-03-07 1989-02-28 Wasserlösliche antineoplastische taxolderivate. ATE109002T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/165,173 US4942184A (en) 1988-03-07 1988-03-07 Water soluble, antineoplastic derivatives of taxol

Publications (1)

Publication Number Publication Date
ATE109002T1 true ATE109002T1 (de) 1994-08-15

Family

ID=22597770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89903659T ATE109002T1 (de) 1988-03-07 1989-02-28 Wasserlösliche antineoplastische taxolderivate.

Country Status (9)

Country Link
US (1) US4942184A (de)
EP (1) EP0406274B1 (de)
JP (1) JP2680152B2 (de)
AT (1) ATE109002T1 (de)
AU (1) AU620605B2 (de)
CA (1) CA1330436C (de)
DE (1) DE68917129T2 (de)
IL (1) IL89503A (de)
WO (1) WO1989008453A1 (de)

Families Citing this family (182)

* Cited by examiner, † Cited by third party
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DE68917129T2 (de) 1995-03-02
AU620605B2 (en) 1992-02-20
WO1989008453A1 (en) 1989-09-21
CA1330436C (en) 1994-06-28
AU3286189A (en) 1989-10-05
US4942184A (en) 1990-07-17
EP0406274A4 (en) 1991-08-28
IL89503A (en) 1994-02-27
JPH03505725A (ja) 1991-12-12
EP0406274B1 (de) 1994-07-27
IL89503A0 (en) 1989-09-10
EP0406274A1 (de) 1991-01-09
DE68917129D1 (de) 1994-09-01

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