ATE110084T1 - Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. - Google Patents

Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.

Info

Publication number
ATE110084T1
ATE110084T1 AT86906958T AT86906958T ATE110084T1 AT E110084 T1 ATE110084 T1 AT E110084T1 AT 86906958 T AT86906958 T AT 86906958T AT 86906958 T AT86906958 T AT 86906958T AT E110084 T1 ATE110084 T1 AT E110084T1
Authority
AT
Austria
Prior art keywords
monoclonal antibody
human monoclonal
anticytomegaloviral
production
cmv
Prior art date
Application number
AT86906958T
Other languages
English (en)
Inventor
Yasuhiko Masuho
Toru Sugano
Yoh-Ichi Matsumoto
Shigeki Fujinaga
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ATE110084T1 publication Critical patent/ATE110084T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C07K16/085—Orthoherpesviridae (F), e.g. pseudorabies virus or Epstein-Barr virus
    • C07K16/089—Cytomegalovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT86906958T 1985-12-06 1986-12-02 Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. ATE110084T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27350485 1985-12-06

Publications (1)

Publication Number Publication Date
ATE110084T1 true ATE110084T1 (de) 1994-09-15

Family

ID=17528811

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86906958T ATE110084T1 (de) 1985-12-06 1986-12-02 Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.

Country Status (7)

Country Link
US (1) US5043281A (de)
EP (1) EP0248909B1 (de)
KR (1) KR910000736B1 (de)
AT (1) ATE110084T1 (de)
AU (1) AU590656B2 (de)
DE (1) DE3650032T2 (de)
WO (1) WO1987003602A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153311A (en) * 1986-11-24 1992-10-06 The Children's Hospital, Incorporated Immunogenic glycoproteins of human cytomegalovirus gCII
US5126130A (en) * 1986-11-24 1992-06-30 The Childrens Hospital Incorporated Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a
US6511665B1 (en) * 1987-11-25 2003-01-28 Immunex Corporation Antibodies to interleukin-1 receptors
EP0436537A4 (en) 1988-01-29 1992-04-08 Chiron Corporation Recombinant cmv neutralizing proteins
SE9201281L (sv) * 1992-04-23 1993-10-24 Bioinvent Int Ab Nya humana monoklonala antikroppar och förfarande för framställning därav
GB9221654D0 (en) * 1992-10-15 1992-11-25 Scotgen Ltd Recombinant human anti-cytomegalovirus antibodies
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus
AU3993695A (en) * 1994-12-07 1996-06-26 Fujisawa Pharmaceutical Co., Ltd. Method of measuring the concentration of fk506-binding protein
DK0960336T3 (da) 1996-07-12 2003-02-10 Organon Teknika Bv Peptidreagens til påvisning af humant cytomelagovirus (CMV)
JPWO2007094423A1 (ja) * 2006-02-15 2009-07-09 株式会社イーベック ヒトサイトメガロウイルスに結合するヒトのモノクローナル抗体並びにその抗原結合部分
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
WO2009085383A1 (en) * 2007-12-19 2009-07-09 Dcb-Usa Llc Anti-human cytomegalovirus antibodies
PE20141398A1 (es) 2008-07-16 2014-10-18 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano
AU2008359583B2 (en) * 2008-07-16 2012-04-05 Institute For Research In Biomedicine Human cytomegalovirus neutralising antibodies and use thereof
RU2393219C1 (ru) * 2008-12-15 2010-06-27 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) Штамм гибридных клеток животного mus musculus l. 5f10 - продуцент моноклональных антител, используемых для выявления белка рр65 цитомегаловируса человека
SI2420572T1 (sl) 2009-04-01 2015-10-30 Evec Incorporated Monoklonsko protitelo, ki je sposobno vezave na specifični diskontinuirani epitop, ki se pojavi pri regiji ad1 glikoproteina gb človeškega citomegalovirusa, in njegov antigen-vezavni fragment
US20110033389A1 (en) * 2009-04-29 2011-02-10 Zhifeng Chen Modified antibodies for passive immunotherapy
AU2010334809C1 (en) 2009-12-23 2015-02-26 Agenus Inc. Binding members for human cytomegalovirus
WO2019188552A1 (ja) * 2018-03-27 2019-10-03 森永乳業株式会社 微生物の細胞及び／又はウイルスの測定方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4574116A (en) * 1983-01-13 1986-03-04 The Board Of Trustees Of The Leland Stanford Jr. University Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes
FR2543570B1 (fr) * 1983-03-31 1985-08-09 Pasteur Institut Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains
GB8404368D0 (en) * 1984-02-20 1984-03-28 Cogent Ltd Monoclonal antibodies to human cytomegalovirus
EP0198086B1 (de) * 1984-09-28 1991-01-16 Teijin Limited Maus/mensch-hybridoma mit erzeugung von antiviralen menschlichen antikörpern, deren herstellung und antivirale menschliche monoklonale antikörper
JP2933786B2 (ja) * 1992-10-13 1999-08-16 甲南電機株式会社 逃がし弁
JPH06181782A (ja) * 1992-12-21 1994-07-05 Mitsubishi Petrochem Co Ltd 酵素反応方法

Also Published As

Publication number Publication date
EP0248909A4 (de) 1989-11-07
EP0248909A1 (de) 1987-12-16
WO1987003602A1 (fr) 1987-06-18
US5043281A (en) 1991-08-27
DE3650032T2 (de) 1995-03-09
EP0248909B1 (de) 1994-08-17
KR910000736B1 (ko) 1991-02-06
AU6721887A (en) 1987-06-30
AU590656B2 (en) 1989-11-09
KR880700823A (ko) 1988-04-12
DE3650032D1 (de) 1994-09-22

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time