ATE110789T1 - Vermehrung und nachweis von nukleinsauresequenzen. - Google Patents

Vermehrung und nachweis von nukleinsauresequenzen.

Info

Publication number
ATE110789T1
ATE110789T1 AT89115959T AT89115959T ATE110789T1 AT E110789 T1 ATE110789 T1 AT E110789T1 AT 89115959 T AT89115959 T AT 89115959T AT 89115959 T AT89115959 T AT 89115959T AT E110789 T1 ATE110789 T1 AT E110789T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid sequences
propagation
detection
pair members
Prior art date
Application number
AT89115959T
Other languages
English (en)
Inventor
Thomas G Laffler
Stanley Robert Bouma
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE110789T1 publication Critical patent/ATE110789T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT89115959T 1988-08-30 1989-08-30 Vermehrung und nachweis von nukleinsauresequenzen. ATE110789T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23864988A 1988-08-30 1988-08-30
US39405189A 1989-08-17 1989-08-17

Publications (1)

Publication Number Publication Date
ATE110789T1 true ATE110789T1 (de) 1994-09-15

Family

ID=26931836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89115959T ATE110789T1 (de) 1988-08-30 1989-08-30 Vermehrung und nachweis von nukleinsauresequenzen.

Country Status (8)

Country Link
EP (1) EP0357011B1 (de)
JP (1) JP3001906B2 (de)
KR (1) KR970006389B1 (de)
AT (1) ATE110789T1 (de)
AU (1) AU629845B2 (de)
CA (1) CA1336394C (de)
DE (1) DE68917834T2 (de)
ES (1) ES2063091T3 (de)

Families Citing this family (43)

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US5753433A (en) * 1909-12-05 1998-05-19 Boehringer Mannheim Gmbh Method for the sensitive detection of nucleic acids
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
CA2002076A1 (en) * 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
US5536648A (en) * 1988-12-09 1996-07-16 Amrad Corporation Limited Amplified DNA assay using a double stranded DNA binding protein
CA2004326A1 (en) * 1988-12-23 1990-06-23 Nanibushan Dattagupta Assay of sequences using amplified genes
GB8926269D0 (en) * 1989-11-21 1990-01-10 Dynal As Plasmid
DE4001154A1 (de) * 1990-01-17 1991-07-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von modifizierten nukleinsaeuren
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
EP0519016A1 (de) * 1990-03-07 1992-12-23 F.Hoffmann-La Roche & Co. Aktiengesellschaft Verfahren zur diagnose der lyme-krankheit
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
FR2660925B1 (fr) * 1990-04-11 1994-07-01 Inst Nat Sante Rech Med Procede de fixation d'une sequence nucleotidique sur un support solide, applications et necessaires pour leur mise en óoeuvre.
JPH0491790A (ja) * 1990-08-02 1992-03-25 Shionogi & Co Ltd ２段階ｐｃｒ法
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
FR2669347A1 (fr) * 1990-11-15 1992-05-22 Inst Nat Sante Rech Med Procede permettant d'effectuer au moins deux reactions successives, en evitant les risques de contamination, notamment applicable aux techniques d'amplification de l'adn ou de l'arn.
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
IT1252295B (it) * 1991-11-15 1995-06-08 Schiapparelli Diagnostici Ismu Metodo per rivelare acidi nucleici e relativo kit diagnostico
WO1993015222A1 (fr) * 1992-01-29 1993-08-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procede pour eviter les risques de contamination, notamment applicable aux techniques d'amplification de l'adn ou de l'arn
EP0633944B1 (de) * 1992-03-31 2000-11-08 Abbott Laboratories Verfahren zur mehrfachen ligase-kettenreaktion
US6100099A (en) 1994-09-06 2000-08-08 Abbott Laboratories Test strip having a diagonal array of capture spots
US5869252A (en) * 1992-03-31 1999-02-09 Abbott Laboratories Method of multiplex ligase chain reaction
US5858650A (en) * 1992-04-03 1999-01-12 Abbott Laboratories Methods for inactivating nucleotide sequences and metal chelates for use therein
GB9208000D0 (en) * 1992-04-10 1992-05-27 Univ London Quantitative viral assay
DE4301693A1 (de) * 1993-01-22 1994-07-28 Cytech Biomedical Inc Verfahren zur Amplifikation und Verfahren zum Nachweis von Polynucleotidsequenzen an fester Phase
ATE215993T1 (de) * 1995-05-19 2002-04-15 Abbott Lab Nachweis von nukleinsäuren mit breitem dynamikbereich unter verwendung von aggregat- primer-reihen
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
EP2369007B1 (de) 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Erkennung von Nukleinsäuresequenz-Unterschieden mittels der gleichzeitigen Ligaseerkennungs- und Polymerasekettenreaktion
DE19824900B4 (de) * 1998-06-04 2006-05-04 Roche Diagnostics Gmbh DNA-Nachweis über einen Strangreassoziationskomplex
WO2001079548A2 (en) 2000-04-14 2001-10-25 Cornell Research Foundation, Inc. Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction
EP1385997A2 (de) * 2001-04-09 2004-02-04 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. System und methode zum nachweis und zur quantifizierung von nukleinsäuren unter verwendung kovalenter bindungen
ATE519861T1 (de) 2002-06-14 2011-08-15 Gen Probe Inc Zusammensetzungen zum nachweis von hepatitis-b- virus
CA2498320A1 (en) 2002-09-20 2004-04-01 Integrated Dna Technologies, Inc. Anthraquinone quencher dyes, their methods of preparation and use
EP1618214A4 (de) 2003-04-25 2008-02-13 Becton Dickinson Co Nachweis von herpes-simplex-virus typ 1 und 2 durch nukleinsäureamplifikation
WO2005049849A2 (en) 2003-11-14 2005-06-02 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
EP1737985B1 (de) * 2004-04-07 2015-12-30 Access Bio, Inc. System für den nachweis von nukleinsäuren
JP2008545659A (ja) 2005-05-20 2008-12-18 インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド オリゴヌクレオチドを標識する化合物及び方法
JPWO2009034842A1 (ja) * 2007-09-11 2010-12-24 株式会社カネカ 核酸検出方法、および核酸検出キット
FR2950629B1 (fr) 2009-09-25 2013-12-06 Commissariat Energie Atomique Composes fluorescents, polymerisables, de la 7-hydroxycoumarine, leur preparation, polymeres fluorescents de ceux-ci et capteurs chimiques les comprenant.
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2553123B1 (de) 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Verfahren zur verstärkung einer nukleinsäurehybridisierung
AU2011299233B2 (en) 2010-09-07 2016-09-15 Integrated Dna Technologies, Inc. Modifications for antisense compounds
KR20160127753A (ko) 2014-02-05 2016-11-04 후소 야쿠힝 고교 가부시끼가이샤 마스크 올리고뉴클레오티드를 이용한 핵산의 검출, 정량 방법 및 그 장치

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI72146C (fi) * 1985-01-02 1987-04-13 Orion Yhtymae Oy Foerfarande foer identifiering av nukleinsyror.
ES8706823A1 (es) * 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
FI76119C (fi) * 1986-02-27 1988-09-09 Orion Yhtymae Oy Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet.
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
CA1341584C (en) * 1988-04-06 2008-11-18 Bruce Wallace Method of amplifying and detecting nucleic acid sequences
JP3068848B2 (ja) * 1988-12-09 2000-07-24 アムラド・コーポレイション・リミテッド 増幅ｄｎａ検定
KR920700360A (ko) * 1989-03-22 1992-02-19 하리크 프리드리히 미끄럼 베어링

Also Published As

Publication number Publication date
JP3001906B2 (ja) 2000-01-24
KR900003379A (ko) 1990-03-26
AU629845B2 (en) 1992-10-15
AU4028189A (en) 1990-03-08
DE68917834D1 (de) 1994-10-06
CA1336394C (en) 1995-07-25
EP0357011A3 (de) 1991-06-26
EP0357011A2 (de) 1990-03-07
ES2063091T3 (es) 1995-01-01
KR970006389B1 (en) 1997-04-28
DE68917834T2 (de) 1995-01-26
EP0357011B1 (de) 1994-08-31
JPH02174698A (ja) 1990-07-06

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee