ATE111454T1 - 4,5,6,7-tetrahydrobenzimidazol-derivate und ihre herstellung. - Google Patents

4,5,6,7-tetrahydrobenzimidazol-derivate und ihre herstellung.

Info

Publication number
ATE111454T1
ATE111454T1 AT89313415T AT89313415T ATE111454T1 AT E111454 T1 ATE111454 T1 AT E111454T1 AT 89313415 T AT89313415 T AT 89313415T AT 89313415 T AT89313415 T AT 89313415T AT E111454 T1 ATE111454 T1 AT E111454T1
Authority
AT
Austria
Prior art keywords
group
atom
production
hydrogen atom
lower alkyl
Prior art date
Application number
AT89313415T
Other languages
English (en)
Inventor
Mitsuaki Ohta
Tokuo Koide
Takeshi Suzuki
Akira Matsuhisa
Isao Yanagisawa
Keiji Miyata
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26389240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE111454(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE111454T1 publication Critical patent/ATE111454T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Reinforced Plastic Materials (AREA)
  • Adhesive Tapes (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Steroid Compounds (AREA)
AT89313415T 1988-12-22 1989-12-21 4,5,6,7-tetrahydrobenzimidazol-derivate und ihre herstellung. ATE111454T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32532788 1988-12-22
JP4889689 1989-02-28

Publications (1)

Publication Number Publication Date
ATE111454T1 true ATE111454T1 (de) 1994-09-15

Family

ID=26389240

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89313415T ATE111454T1 (de) 1988-12-22 1989-12-21 4,5,6,7-tetrahydrobenzimidazol-derivate und ihre herstellung.

Country Status (15)

Country Link
US (1) US4977175A (de)
EP (1) EP0376624B1 (de)
KR (1) KR900009608A (de)
CN (1) CN1027536C (de)
AT (1) ATE111454T1 (de)
AU (1) AU630397B2 (de)
CA (1) CA2004911A1 (de)
DE (1) DE68918257T2 (de)
DK (1) DK653089A (de)
ES (1) ES2063831T3 (de)
FI (1) FI896075A7 (de)
IE (1) IE65639B1 (de)
NO (1) NO178188C (de)
PT (1) PT92609B (de)
YU (1) YU47216B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0381422B1 (de) * 1989-02-02 1996-10-23 Yamanouchi Pharmaceutical Co. Ltd. Tetrahydrobenzimidazol-Derivate
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
GB9225141D0 (en) * 1992-12-01 1993-01-20 Smithkline Beecham Corp Chemical compounds
US5262537A (en) * 1993-03-19 1993-11-16 Anaquest, Inc. Derivatives of 4,5,6,7-tetrahydroimidazo-[4,5-c]pyridinyl-6-carboxylic acid
WO1997024334A1 (en) 1995-12-28 1997-07-10 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole derivatives
TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
JP2003527395A (ja) * 2000-03-17 2003-09-16 ノボ ノルディスク アクティーゼルスカブ ヒスタミンｈ３受容体リガンドとしての縮環イミダゾール
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
AU2003237881A1 (en) 2002-05-17 2003-12-02 Neurogen Corporation Substituted ring-fused imidazole derivates: gabaa receptor ligands
ES2833251T3 (es) * 2016-08-16 2021-06-14 Bayer Cropscience Ag Procedimiento para producir derivados de 2-(3,6-dihalopiridin-2-il)-3h-imidazol[4,5-c]piridina y compuestos relacionados por reacción del derivado de piridina 3h-imidazol[4,5-c] con una base organometálica de zinc-amina

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1260294A (en) * 1968-03-15 1972-01-12 Rhein Chemie Holding G M B H 4,5,6,7-tetrahydrobenzimidazoles, process for their production and their use as corrosion inhibitors and antioxidants
DE1948795A1 (de) * 1969-09-26 1971-04-08 Rhein Chemie Rheinau Gmbh 4,5,6,7-Tetrahydrobenzimidazole,Verfahren zu ihrer Herstellung und ihre Verwendung als Korrosionsinhibitoren und Alterungsschutzmittel
US3987054A (en) * 1970-09-23 1976-10-19 Pliva Pharmaceutical And Chemical Works 4,5,6,7-tetrahydrobenzimidazoles
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
SE460359B (sv) * 1984-01-25 1989-10-02 Glaxo Group Ltd 3-imidazolylmetyltetrahydrokarbazoloner, foerfarande foer framstaellning av dessa och en farmaceutisk komposition
DE3650772T2 (de) * 1985-04-27 2003-04-03 F. Hoffmann-La Roche Ag, Basel Derivate von Indazole-3-carboxamide und -3-carboxylsäure
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents

Also Published As

Publication number Publication date
EP0376624B1 (de) 1994-09-14
AU630397B2 (en) 1992-10-29
ES2063831T3 (es) 1995-01-16
IE894185L (en) 1990-06-22
DK653089D0 (da) 1989-12-21
DE68918257D1 (de) 1994-10-20
YU243989A (en) 1991-02-28
YU47216B (sh) 1995-01-31
FI896075A0 (fi) 1989-12-19
DK653089A (da) 1990-06-23
PT92609B (pt) 1995-09-12
CA2004911A1 (en) 1990-06-22
NO178188C (no) 1996-02-07
NO895198L (no) 1990-06-25
NO178188B (no) 1995-10-30
PT92609A (pt) 1990-06-29
CN1027536C (zh) 1995-02-01
US4977175A (en) 1990-12-11
EP0376624A1 (de) 1990-07-04
DE68918257T2 (de) 1995-02-02
FI896075A7 (fi) 1990-06-23
IE65639B1 (en) 1995-11-15
KR900009608A (ko) 1990-07-05
CN1043706A (zh) 1990-07-11
AU4714589A (en) 1990-06-28
NO895198D0 (no) 1989-12-21

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