ATE125540T1 - Imidazochinolon-derivate. - Google Patents

Imidazochinolon-derivate.

Info

Publication number: ATE125540T1
Authority: AT; Austria
Prior art keywords: alkyl; cycloalkyl; substituted; hydrogen; aralkenyl
Prior art date: 1989-03-07

Application number

AT90104336T

Other languages

English (en)

Inventor

Fumio Suzuki

Takeshi Kuroda

Yoshisuke Nakazato

Harushiko Manabe

Kenji Ohmori

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-07

Filing date

1990-03-07

Publication date

1995-08-15

1990-03-07 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1995-08-15 Application granted granted Critical

1995-08-15 Publication of ATE125540T1 publication Critical patent/ATE125540T1/de

Links

HOPZBJPSUKPLDT-UHFFFAOYSA-N imidazo[4,5-h]quinolin-2-one Chemical class C1=CN=C2C3=NC(=O)N=C3C=CC2=C1 HOPZBJPSUKPLDT-UHFFFAOYSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 5
125000000753 cycloalkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 3
125000003342 alkenyl group Chemical group 0.000 abstract 2
-1 alkoxyalkly Chemical group 0.000 abstract 2
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
230000003266 anti-allergic effect Effects 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000005239 aroylamino group Chemical group 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
230000003182 bronchodilatating effect Effects 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT90104336T 1989-03-07 1990-03-07 Imidazochinolon-derivate. ATE125540T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP5414889		1989-03-07

Publications (1)

Publication Number	Publication Date
ATE125540T1 true ATE125540T1 (de)	1995-08-15

Family

ID=12962468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90104336T ATE125540T1 (de)	1989-03-07	1990-03-07	Imidazochinolon-derivate.

Country Status (5)

Country	Link
US (1)	US4994468A (de)
EP (1)	EP0386722B1 (de)
AT (1)	ATE125540T1 (de)
CA (1)	CA2011504C (de)
DE (1)	DE69021101T2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8928281D0 (en) *	1989-12-14	1990-02-21	Smith Kline French Lab	Compounds
US5389640A (en)	1991-03-01	1995-02-14	Minnesota Mining And Manufacturing Company	1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
EP0614897A4 (de) *	1991-11-25	1995-02-01	Kyowa Hakko Kogyo Kk	Imidazonaphthyridin derivat.
CA2103660A1 (en) *	1991-12-12	1993-06-13	Fumio Suzuki	Thienoimidazopyridone derivatives
US6608201B2 (en)	1992-08-28	2003-08-19	3M Innovative Properties Company	Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
EP0773219A4 (de) *	1994-07-29	1997-10-29	Mochida Pharm Co Ltd	Imidazochinolin-derivat
GB0211649D0 (en)	2002-05-21	2002-07-03	Novartis Ag	Organic compounds
MD20140130A2 (ro)	2012-06-29	2015-04-30	Pfizer Inc.	4-(amino-substituite)-7H-pirolo[2,3-d]pirimidine noi ca inhibitori de LRRK2
CA2933767C (en)	2013-12-17	2018-11-06	Pfizer Inc.	Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
MX377305B (es) *	2015-09-14	2025-03-07	Pfizer	DERIVADOS DE IMIDAZO[4,5-c]QUINOLINA E IMIDAZO[4,5-c][1,5]NAFTIRIDINA NOVEDOSOS COMO INHIBIDORES DE LRRK2.
WO2018163030A1 (en) *	2017-03-10	2018-09-13	Pfizer Inc.	Cyclic substituted imidazo[4,5-c]quinoline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA848968B (en) *	1983-11-18	1986-06-25	Riker Laboratories Inc	1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
CA1271477A (en) *	1983-11-18	1990-07-10	John F. Gerster	1h-imidazo[4,5-c]quinolin-4-amines
IL73534A (en) *	1983-11-18	1990-12-23	Riker Laboratories Inc	1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds

1990
- 1990-03-05 CA CA002011504A patent/CA2011504C/en not_active Expired - Fee Related
- 1990-03-05 US US07/489,025 patent/US4994468A/en not_active Expired - Fee Related
- 1990-03-07 EP EP90104336A patent/EP0386722B1/de not_active Expired - Lifetime
- 1990-03-07 DE DE69021101T patent/DE69021101T2/de not_active Expired - Fee Related
- 1990-03-07 AT AT90104336T patent/ATE125540T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2011504C (en)	1998-06-02
US4994468A (en)	1991-02-19
EP0386722A1 (de)	1990-09-12
EP0386722B1 (de)	1995-07-26
CA2011504A1 (en)	1990-09-07
DE69021101D1 (de)	1995-08-31
DE69021101T2 (de)	1995-12-21

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Legal Events

Date	Code	Title	Description
1996-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties